Synthesis and oral antiallergic activity of carboxylic acids derived from imidazo[2,1-c][1,4]benzoxazines, imidazo[1,2-a]quinolines, imidazo[1,2-a]quinoxalines, imidazo[1,2-a]quinoxalinones, pyrrolo[1,2-a]quinoxalinones, pyrrolo[2,3-a]quinoxalinones, and imidazo[2,1-b]benzothiazoles
Ager, Ian R, Barnes, Alan C, Danswan, Geoffrey W, Hairsine, Peter W, Kay, David P, Kennewell, Peter D, Matharu, Saroop S, Miller, Peter, Robson, Peter
Published in Journal of medicinal chemistry (01.06.1988)
Published in Journal of medicinal chemistry (01.06.1988)
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Journal Article
Synthesis, Structure−Activity Relationships, and Pharmacokinetic Properties of Dihydroorotate Dehydrogenase Inhibitors: 2-Cyano-3-cyclopropyl-3-hydroxy- N-[3‘-methyl-4‘-(trifluoromethyl)phenyl]propenamide and Related Compounds
Kuo, Elizabeth A, Hambleton, Philip T, Kay, David P, Evans, Phillip L, Matharu, Saroop S, Little, Edward, McDowall, Neil, Jones, C. Beth, Hedgecock, Charles J. R, Yea, Christopher M, Chan, A. W. Edith, Hairsine, Peter W, Ager, Ian R, Tully, W. Roger, Williamson, Richard A, Westwood, Robert
Published in Journal of medicinal chemistry (08.11.1996)
Published in Journal of medicinal chemistry (08.11.1996)
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Journal Article
(Imidazo[1,2-a]pyrimidin-2-yl)phenylmethanones and related compounds as potential nonsedative anxiolytics
Clements-Jewery, Stephen, Danswan, Geoffrey, Gardner, Colin R, Matharu, Saroop S, Murdoch, Robert, Tully, W. Roger, Westwood, Robert
Published in Journal of medicinal chemistry (01.06.1988)
Published in Journal of medicinal chemistry (01.06.1988)
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Journal Article
Synthesis and antitussive activity of aminotetra- (and -hexa-) hydrodibenzofurans
Matharu, Saroop S, Rowlands, David A, Taylor, John B, Westwood, Robert
Published in Journal of medicinal chemistry (01.02.1977)
Published in Journal of medicinal chemistry (01.02.1977)
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Journal Article
The synthesis and evaluation of peptidyl aspartyl aldehydes as inhibitors of ice
Mullican, Michael D., Lauffer, David J., Gillespie, Roger J., Matharu, Saroop S., Kay, David, Porritt, Geoffrey M., Evans, Phillip L., Golec, Julian M.C., Murcko, Mark A., Luong, Yu-Ping, Raybuck, Scott A., Livingston, David J.
Published in Bioorganic & medicinal chemistry letters (06.10.1994)
Published in Bioorganic & medicinal chemistry letters (06.10.1994)
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inibidores de enzima conversora de interleucina-1beta, bem como composição farmacêutica
David Bebbington, Wolf Herman Fridman, Keith P. Wilson, Andrea L. C. Robidoux, Philip L. Nyce, Michael D. Mullican, Robert E. Zelle, M. Woods Wannamaker, Michael Su, Roger J. Gillespie, Julian M. C. Golec, David J. Lauffer, David J. Livingston, Mark A. Murcko, Mark J. Batchelor, Robert Murdoch, Saroop S. Matharu, Yong Gu, Guy W. Bemis
Year of Publication 17.04.2018
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Year of Publication 17.04.2018
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Inhibitors of interleukin-1beta converting enzyme
BEBBINGTON, DAVID, FRIDMAN, WOLF HERMAN, NYCE, PHILIP L, ROBIDOUX, ANDREA L.C, MURCKO, MARK A, GILLESPIE, ROGER J, LAUFFER, DAVID J, MURDOCH, ROBERT, GU, YONG, BATCHELOR, MARK J, WANNAMAKER, M. WOODS, SU, MICHAEL, ZELLE, ROBERT E, MULLICAN, MICHAEL D, LIVINGSTON, DAVID J, GOLEC, JULIAN M.C, MATHARU, SAROOP S, WILSON, KEITH P, BEMIS, GUY W
Year of Publication 06.04.2011
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Year of Publication 06.04.2011
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Inhibitors of interleukin-1beta converting enzyme
BEBBINGTON, DAVID, FRIDMAN, WOLF HERMAN, NYCE, PHILIP L, ROBIDOUX, ANDREA L.C, MURCKO, MARK A, GILLESPIE, ROGER J, LAUFFER, DAVID J, MURDOCH, ROBERT, GU, YONG, BATCHELOR, MARK J, WANNAMAKER, M. WOODS, SU, MICHAEL, ZELLE, ROBERT E, MULLICAN, MICHAEL D, LIVINGSTON, DAVID J, GOLEC, JULIAN M.C, MATHARU, SAROOP S, WILSON, KEITH P, BEMIS, GUY W
Year of Publication 16.03.2011
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Year of Publication 16.03.2011
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Inhibitors of interleukin-1beta converting enzyme, pharmaceutical composition containing thereof and process for their preparation
BEMIS GUY W, GILLESPIE ROGER J, MATHARU SAROOP S, LIVINGSTON DAVID J, WILSON KEITH P, GOLEC JULIAN M. C, MULLICAN MICHAEL D, NYCE PHILIP L, ROBIDOUX ANDREA L. C, GU YONG, SU MICHAEL, LAUFFER DAVID J, ZELLE ROBERT E, MURDOCH ROBERT, FRIDMAN WOLF HERMAN, BEBBINGTON DAVID, WANNAMAKER M. WOODS, BATCHELOR MARK J, MURCKO MARK A
Year of Publication 08.03.2010
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Year of Publication 08.03.2010
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INHIBITORS OF INTERLEUKIN-1.BETA. CONVERTING ENZYME
BEBBINGTON, DAVID, FRIDMAN, WOLF HERMAN, NYCE, PHILIP L, MURCKO, MARK A, GILLESPIE, ROGER J, MURDOCH, ROBERT, LAUFFER, DAVID J, GU, YONG, GOLEC, JULIAN M. C, ROBIDOUX, ANDREA L. C, BATCHELOR, MARK J, WANNAMAKER, M. WOODS, SU, MICHAEL, ZELLE, ROBERT E, MULLICAN, MICHAEL D, LIVINGSTON, DAVID J, WILSON, KEITH P, MATHARU, SAROOP S, BEMIS, GUY W
Year of Publication 19.01.2010
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Year of Publication 19.01.2010
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Inhibitors of interleukin-1ß converting enzyme
BEBBINGTON, DAVID, NYCE, PHILIP L, GILLESPIE, ROGER, J, MURCKO, MARK A, ROBIDOUX, ANDREA L, BEMIS, GUY, W, MURDOCH, ROBERT, GU, YONG, GOLEC, JULIAN M. C, BATCHELOR, MARK J, WANNAMAKER, M. WOODS, FRIDMAN, WOLF, HERMAN, SU, MICHAEL, ZELLE, ROBERT E, LAUFER, DAVID J, MULLICAN, MICHAEL D, LIVINGSTON, DAVID J, MATHARU, SAROOP S, WILSON, KEITH P
Year of Publication 06.01.2010
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Year of Publication 06.01.2010
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Inhibitors of interleukin-1beta converting enzyme
BEMIS GUY W, GOLEC JULIAN M, GILLESPIE ROGER J, MATHARU SAROOP S, LIVINGSTON DAVID J, FRIDMAN WOLF H, MULLICAN MICHAEL D, LAUFFER DAVID J, ZELLE ROBERT E, MURDOCH ROBERT, BEBBINGTON DAVID, BATCHELOR MARK J, MURCKO MARK A
Year of Publication 14.02.2008
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Year of Publication 14.02.2008
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Inhibitors of interleukin-1ß converting enzyme
BEBBINGTON, DAVID, NYCE, PHILIP L, GILLESPIE, ROGER, J, MURCKO, MARK A, ROBIDOUX, ANDREA L, BEMIS, GUY, W, MURDOCH, ROBERT, GU, YONG, GOLEC, JULIAN M. C, BATCHELOR, MARK J, WANNAMAKER, M. WOODS, FRIDMAN, WOLF, HERMAN, SU, MICHAEL, ZELLE, ROBERT E, LAUFER, DAVID J, MULLICAN, MICHAEL D, LIVINGSTON, DAVID J, MATHARU, SAROOP S, WILSON, KEITH P
Year of Publication 29.07.2009
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Year of Publication 29.07.2009
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Inhibitorer for interleukin-1 konverterende enzym
BEMIS GUY W, GILLESPIE ROGER J, MATHARU SAROOP S, LIVINGSTON DAVID J, ROBINDOUX ANDREA L. C, WILSON KEITH P, GOLEC JULIAN M C, MULLICAN MICHAEL D, BEBBINGTON DAVID JOHN, NYCE PHILIP L, GU YONG, SU MICHAEL, ZELLE ROBERT E, MURDOCH ROBERT, FRIDMAN WOLF HERMAN, WANNAMAKER M. WOODS, BATCHELOR MARK J, LAUFFER DAVID JEFFREY, MURCKO MARK A
Year of Publication 09.03.2009
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Year of Publication 09.03.2009
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INHIBITOR OF INTERLEUKIN-1beta CONVERTING ENZYME
BEMIS GUY W, GILLESPIE ROGER J, MATHARU SAROOP S, LIVINGSTON DAVID J, WILSON KEITH P, GOLEC JULIAN M C, MULLICAN MICHAEL D, NYCE PHILIP L, GU YONG, WANNAMAKER M WOODS, SU MICHAEL, ROBIDOUX ANDREA L C, LAUFFER DAVID J, ZELLE ROBERT E, MURDOCH ROBERT, FRIDMAN WOLF HERMAN, BEBBINGTON DAVID, BATCHELOR MARK J, MURCKO MARK A
Year of Publication 27.11.2008
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Year of Publication 27.11.2008
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Inhibitors of interleukin-1beta converting enzyme
BATCHELOR MARK J.,BEBBINGTON DAVID,BEMIS GUY W.,FRIDMAN WOLF H.,GILLESPIE ROGER J.,GOLEC JULIAN M.,LAUFFER DAVID J.,LIVINGSTON DAVID J.,MATHARU SAROOP S.,MULLICAN MICHAEL D.,MURCKO MARK A.,MURDOCH ROB
Year of Publication 01.03.2006
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Year of Publication 01.03.2006
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