The role of the PI3K pathway in colorectal cancer
Papadatos-Pastos, Dionysios, Rabbie, Roy, Ross, Paul, Sarker, Debashis
Published in Critical reviews in oncology/hematology (01.04.2015)
Published in Critical reviews in oncology/hematology (01.04.2015)
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Journal Article
USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer
Nelson, Jessica K, Thin, May Zaw, Evan, Theodore, Howell, Steven, Wu, Mary, Almeida, Bruna, Legrave, Nathalie, Koenis, Duco S, Koifman, Gabriela, Sugimoto, Yoichiro, Llorian Sopena, Miriam, MacRae, James, Nye, Emma, Howell, Michael, Snijders, Ambrosius P, Prachalias, Andreas, Zen, Yoh, Sarker, Debashis, Behrens, Axel
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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Journal Article
Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer
Kocher, Hemant M, Basu, Bristi, Froeling, Fieke E M, Sarker, Debashis, Slater, Sarah, Carlin, Dominic, deSouza, Nandita M, De Paepe, Katja N, Goulart, Michelle R, Hughes, Christine, Imrali, Ahmet, Roberts, Rhiannon, Pawula, Maria, Houghton, Richard, Lawrence, Cheryl, Yogeswaran, Yathushan, Mousa, Kelly, Coetzee, Carike, Sasieni, Peter, Prendergast, Aaron, Propper, David J
Published in Nature communications (24.09.2020)
Published in Nature communications (24.09.2020)
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Journal Article
First-in-human study of the PARP/tankyrase inhibitor E7449 in patients with advanced solid tumours and evaluation of a novel drug-response predictor
Plummer, Ruth, Dua, Divyanshu, Cresti, Nicola, Drew, Yvette, Stephens, Peter, Foegh, Marie, Knudsen, Steen, Sachdev, Pallavi, Mistry, Bipin M, Dixit, Vaishali, McGonigle, Sharon, Hall, Nancy, Matijevic, Mark, McGrath, Shannon, Sarker, Debashis
Published in British journal of cancer (01.08.2020)
Published in British journal of cancer (01.08.2020)
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Journal Article
Targeting the PI3K/AKT Pathway for the Treatment of Prostate Cancer
Sarker, Debashis, Reid, Alison H M, Yap, Timothy A, de Bono, Johann S
Published in Clinical cancer research (01.08.2009)
Published in Clinical cancer research (01.08.2009)
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Journal Article
Efficacy and Safety Results from a Phase 2, Randomized, Double-Blind Study of Enzalutamide Versus Placebo in Advanced Hepatocellular Carcinoma
Ryoo, Baek-Yeol, Palmer, Daniel H., Park, Sook Ryun, Rimassa, Lorenza, Debashis Sarker, Daniele, Bruno, Steinberg, Joyce, López, Beatriz, Lim, Ho Yeong
Published in Clinical drug investigation (01.09.2021)
Published in Clinical drug investigation (01.09.2021)
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Journal Article
Pharmacodynamic Biomarkers for Molecular Cancer Therapeutics
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Book Chapter
Journal Article
Hepatocellular Carcinoma as a Complication of Vascular Disease of the Liver After Fontan Procedure
Mazzarelli, Chiara, Cannon, Mary D., Hudson, Mark, Heaton, Nigel, Sarker, Debashis, Kane, Pauline, Quaglia, Alberto, Suddle, Abid
Published in Hepatology (Baltimore, Md.) (01.02.2019)
Published in Hepatology (Baltimore, Md.) (01.02.2019)
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Journal Article
PAK4 pathway as a potential therapeutic target in pancreatic cancer
Thillai, Kiruthikah, Sarker, Debashis, Wells, Claire
Published in Future oncology (London, England) (01.03.2018)
Published in Future oncology (London, England) (01.03.2018)
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Journal Article
Deciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?
Thillai, Kiruthikah, Lam, Hoyin, Sarker, Debashis, Wells, Claire M
Published in Oncotarget (21.02.2017)
Published in Oncotarget (21.02.2017)
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Journal Article
Chronic inflammation markers are associated with risk of pancreatic cancer in the Swedish AMORIS cohort study
Sollie, Sam, Michaud, Dominique S, Sarker, Debashis, Karagiannis, Sophia N, Josephs, Debra H, Hammar, Niklas, Santaolalla, Aida, Walldius, Goran, Garmo, Hans, Holmberg, Lars, Jungner, Ingmar, Van Hemelrijck, Mieke
Published in BMC cancer (29.08.2019)
Published in BMC cancer (29.08.2019)
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Journal Article
Histological heterogeneity in primary and metastatic classic combined hepatocellular-cholangiocarcinoma: a case series
De Vito, Claudio, Sarker, Debashis, Ross, Paul, Heaton, Nigel, Quaglia, Alberto
Published in Virchows Archiv : an international journal of pathology (01.11.2017)
Published in Virchows Archiv : an international journal of pathology (01.11.2017)
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Journal Article
Quantification of pancreatic cancer proteome and phosphorylome: indicates molecular events likely contributing to cancer and activity of drug targets
Britton, David, Zen, Yoh, Quaglia, Alberto, Selzer, Stefan, Mitra, Vikram, Löβner, Christopher, Jung, Stephan, Böhm, Gitte, Schmid, Peter, Prefot, Petra, Hoehle, Claudia, Koncarevic, Sasa, Gee, Julia, Nicholson, Robert, Ward, Malcolm, Castellano, Leandro, Stebbing, Justin, Zucht, Hans Dieter, Sarker, Debashis, Heaton, Nigel, Pike, Ian
Published in PloS one (26.03.2014)
Published in PloS one (26.03.2014)
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Journal Article
Effect of Patient Socioeconomic Status on Access to Early-Phase Cancer Trials
MOHD NOOR, Aisyah, SARKER, Debashis, VIZOR, Suzanne, MCLENNAN, Blair, HUNTER, Sarah, SUDER, Aneta, MOLLER, Henrik, SPICER, James F, PAPA, Sophie
Published in Journal of clinical oncology (10.01.2013)
Published in Journal of clinical oncology (10.01.2013)
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Journal Article
A Phase I Pharmacokinetic and Pharmacodynamic Study of TKI258, an Oral, Multitargeted Receptor Tyrosine Kinase Inhibitor in Patients with Advanced Solid Tumors
Sarker, Debashis, Molife, Rhoda, Evans, T R Jeffrey, Hardie, Maryon, Marriott, Cheryl, Butzberger-Zimmerli, Priska, Morrison, Rosemary, Fox, Judith A, Heise, Carla, Louie, Sharianne, Aziz, Natasha, Garzon, Felix, Michelson, Glenn, Judson, Ian R, Jadayel, Dalal, Braendle, Edgar, de Bono, Johann S
Published in Clinical cancer research (01.04.2008)
Published in Clinical cancer research (01.04.2008)
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Journal Article
Serum Immunoglobulin G Is Associated With Decreased Risk of Pancreatic Cancer in the Swedish AMORIS Study
Sollie, Sam, Santaolalla, Aida, Michaud, Dominique S, Sarker, Debashis, Karagiannis, Sophia N, Josephs, Debra H, Hammar, Niklas, Walldius, Goran, Garmo, Hans, Holmberg, Lars, Jungner, Ingmar, Van Hemelrijck, Mieke
Published in Frontiers in oncology (28.02.2020)
Published in Frontiers in oncology (28.02.2020)
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Journal Article