Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in mice
Stowell, Nicole C, Seideman, Jonathan, Raymond, Holly A, Smalley, Karen A, Lamb, Roberta J, Egenolf, Devon D, Bugelski, Peter J, Murray, Lynne A, Marsters, Paul A, Bunting, Rachel A, Flavell, Richard A, Alexopoulou, Lena, San Mateo, Lani R, Griswold, Don E, Sarisky, Robert T, Mbow, M Lamine, Das, Anuk M
Published in Respiratory research (01.06.2009)
Published in Respiratory research (01.06.2009)
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Effects of Single Nucleotide Polymorphisms on Toll-like Receptor 3 Activity and Expression in Cultured Cells
Ranjith-Kumar, C.T., Miller, William, Sun, Jingchuan, Xiong, Jin, Santos, Jon, Yarbrough, Ian, Lamb, Roberta J., Mills, Juliane, Duffy, Karen E., Hoose, Scott, Cunningham, Mark, Holzenburg, Andreas, Mbow, M. Lamine, Sarisky, Robert T., Kao, C. Cheng
Published in The Journal of biological chemistry (15.06.2007)
Published in The Journal of biological chemistry (15.06.2007)
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Deleterious role of TLR3 during hyperoxia-induced acute lung injury
Murray, Lynne A, Knight, Darryl A, McAlonan, Laura, Argentieri, Rochelle, Joshi, Amrita, Shaheen, Furquan, Cunningham, Mark, Alexopolou, Lena, Flavell, Richard A, Sarisky, Robert T, Hogaboam, Cory M
Published in American journal of respiratory and critical care medicine (15.12.2008)
Published in American journal of respiratory and critical care medicine (15.12.2008)
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3-(1,1-Dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, Potent Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase
Tedesco, Rosanna, Shaw, Antony N, Bambal, Ramesh, Chai, Deping, Concha, Nestor O, Darcy, Michael G, Dhanak, Dashyant, Fitch, Duke M, Gates, Adam, Gerhardt, Warren G, Halegoua, Dina L, Han, Chao, Hofmann, Glenn A, Johnston, Victor K, Kaura, Arun C, Liu, Nannan, Keenan, Richard M, Lin-Goerke, Juili, Sarisky, Robert T, Wiggall, Kenneth J, Zimmerman, Michael N, Duffy, Kevin J
Published in Journal of medicinal chemistry (09.02.2006)
Published in Journal of medicinal chemistry (09.02.2006)
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Journal Article
Structural and Functional Analyses of the Human Toll-like Receptor 3: ROLE OF GLYCOSYLATION
Sun, Jingchuan, Duffy, Karen E, Ranjith-Kumar, C. T, Xiong, Jin, Lamb, Roberta J, Santos, Jon, Masarapu, Hema, Cunningham, Mark, Holzenburg, Andreas, Sarisky, Robert T, Mbow, M. Lamine, Kao, Cheng
Published in The Journal of biological chemistry (21.04.2006)
Published in The Journal of biological chemistry (21.04.2006)
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Members of the NF90/NFAR protein group are involved in the life cycle of a positive-strand RNA virus
Isken, Olaf, Grassmann, Claus W., Sarisky, Robert T., Kann, Michael, Zhang, Suisheng, Grosse, Frank, Kao, Peter N., Behrens, Sven-Erik
Published in The EMBO journal (03.11.2003)
Published in The EMBO journal (03.11.2003)
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Toll-Like Receptor 9 Can Be Expressed at the Cell Surface of Distinct Populations of Tonsils and Human Peripheral Blood Mononuclear Cells
EATON-BASSIRI, Ashlyn, DILLON, Susan B, CUNNINGHAM, Mark, RYCYZYN, Michael A, MILLS, Juliane, SARISKY, Robert T, LAMINE MBOW, M
Published in Infection and Immunity (01.12.2004)
Published in Infection and Immunity (01.12.2004)
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Journal Article
Biochemical and Functional Analyses of the Human Toll-like Receptor 3 Ectodomain
Ranjith-Kumar, C.T., Miller, William, Xiong, Jin, Russell, William K., Lamb, Roberta, Santos, Jonathan, Duffy, Karen E., Cleveland, Larissa, Park, Mary, Bhardwaj, Kanchan, Wu, Zhaoxiang, Russell, David H., Sarisky, Robert T., Mbow, M. Lamine, Kao, C. Cheng
Published in The Journal of biological chemistry (09.03.2007)
Published in The Journal of biological chemistry (09.03.2007)
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Journal Article
Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase
Shaw, Antony N., Tedesco, Rosanna, Bambal, Ramesh, Chai, Deping, Concha, Nestor O., Darcy, Michael G., Dhanak, Dashyant, Duffy, Kevin J., Fitch, Duke M., Gates, Adam, Johnston, Victor K., Keenan, Richard M., Lin-Goerke, Juili, Liu, Nannan, Sarisky, Robert T., Wiggall, Kenneth J., Zimmerman, Michael N.
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Journal Article
Resistance Profile of a Hepatitis C Virus RNA-Dependent RNA Polymerase Benzothiadiazine Inhibitor
NGUYEN, Tammy T, GATES, Adam T, GUTSHALL, Lester L, JOHNSTON, Victor K, BAOHUA GU, DUFFY, Kevin J, SARISKY, Robert T
Published in Antimicrobial Agents and Chemotherapy (01.11.2003)
Published in Antimicrobial Agents and Chemotherapy (01.11.2003)
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Journal Article
Identification of small molecule inhibitors of the hepatitis C virus RNA-dependent RNA polymerase from a pyrrolidine combinatorial mixture
Burton, George, Ku, Thomas W., Carr, Thomas J., Kiesow, Terry, Sarisky, Robert T., Lin-Goerke, Juili, Baker, Audrey, Earnshaw, David L., Hofmann, Glenn A., Keenan, Richard M., Dhanak, Dashyant
Published in Bioorganic & medicinal chemistry letters (15.03.2005)
Published in Bioorganic & medicinal chemistry letters (15.03.2005)
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Journal Article
A pathway analysis of poly(I:C)-induced global gene expression change in human peripheral blood mononuclear cells
Huang, C. Chris, Duffy, Karen E, San Mateo, Lani R, Amegadzie, Bernard Y, Sarisky, Robert T, Mbow, M. Lamine
Published in Physiological genomics (12.07.2006)
Published in Physiological genomics (12.07.2006)
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Journal Article
Mechanism of De Novo Initiation by the Hepatitis C Virus RNA-Dependent RNA Polymerase: Role of Divalent Metals
Ranjith-Kumar, C. T., Kim, Young-Chan, Gutshall, Les, Silverman, Carol, Khandekar, Sanjay, Sarisky, Robert T., Kao, C. Cheng
Published in Journal of Virology (01.12.2002)
Published in Journal of Virology (01.12.2002)
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Journal Article
Arresting Initiation of Hepatitis C Virus RNA Synthesis Using Heterocyclic Derivatives
Gu, Baohua, Johnston, Victor K., Gutshall, Lester L., Nguyen, Tammy T., Gontarek, Richard R., Darcy, Michael G., Tedesco, Rosanna, Dhanak, Dashyant, Duffy, Kevin J., Kao, C. Cheng, Sarisky, Robert T.
Published in The Journal of biological chemistry (09.05.2003)
Published in The Journal of biological chemistry (09.05.2003)
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Sustained and specific in vitro inhibition of HIV-1 replication by a protease inhibitor encapsulated in gp120-targeted liposomes
Clayton, Reginald, Ohagen, Asa, Nicol, Francois, Del Vecchio, Alfred M., Jonckers, Tim H.M., Goethals, Olivia, Van Loock, Marnix, Michiels, Lieve, Grigsby, John, Xu, Zheng, Zhang, Yuan Peng, Gutshall, Lester L., Cunningham, Mark, Jiang, Haiyan, Bola, Sharon, Sarisky, Robert T., Hertogs, Kurt
Published in Antiviral research (01.11.2009)
Published in Antiviral research (01.11.2009)
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