Combining antibody–drug conjugates and immune-mediated cancer therapy: What to expect?
Gerber, Hans-Peter, Sapra, Puja, Loganzo, Frank, May, Chad
Published in Biochemical pharmacology (15.02.2016)
Published in Biochemical pharmacology (15.02.2016)
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Journal Article
A general approach to site-specific antibody drug conjugates
Tian, Feng, Lu, Yingchun, Manibusan, Anthony, Sellers, Aaron, Tran, Hon, Sun, Ying, Phuong, Trung, Barnett, Richard, Hehli, Brad, Song, Frank, DeGuzman, Michael J., Ensari, Semsi, Pinkstaff, Jason K., Sullivan, Lorraine M., Biroc, Sandra L., Ho Cho, Schultz, Peter G., DiJoseph, John, Dougher, Maureen, Ma, Dangshe, Dushin, Russell, Leal, Mauricio, Tchistiakova, Lioudmila, Feyfant, Eric, Gerber, Hans-Peter, Sapra, Puja
Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (04.02.2014)
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Journal Article
A PTK7-targeted antibody-drug conjugate reduces tumor-initiating cells and induces sustained tumor regressions
Damelin, Marc, Bankovich, Alexander, Bernstein, Jeffrey, Lucas, Justin, Chen, Liang, Williams, Samuel, Park, Albert, Aguilar, Jorge, Ernstoff, Elana, Charati, Manoj, Dushin, Russell, Aujay, Monette, Lee, Christina, Ramoth, Hanna, Milton, Milly, Hampl, Johannes, Lazetic, Sasha, Pulito, Virginia, Rosfjord, Edward, Sun, Yongliang, King, Lindsay, Barletta, Frank, Betts, Alison, Guffroy, Magali, Falahatpisheh, Hadi, O'Donnell, Christopher J, Stull, Robert, Pysz, Marybeth, Escarpe, Paul, Liu, David, Foord, Orit, Gerber, Hans Peter, Sapra, Puja, Dylla, Scott J
Published in Science translational medicine (11.01.2017)
Published in Science translational medicine (11.01.2017)
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Journal Article
Antibody-drug conjugates: an emerging modality for the treatment of cancer
Leal, Mauricio, Sapra, Puja, Hurvitz, Sara A., Senter, Peter, Wahl, Alan, Schutten, Melissa, Shah, Dhaval K., Haddish-Berhane, Nahor, Kabbarah, Omar
Published in Annals of the New York Academy of Sciences (01.08.2014)
Published in Annals of the New York Academy of Sciences (01.08.2014)
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Journal Article
Novel Prodrugs of SN38 Using Multiarm Poly(ethylene glycol) Linkers
Zhao, Hong, Rubio, Belen, Sapra, Puja, Wu, Dechun, Reddy, Prasanna, Sai, Prakash, Martinez, Anthony, Gao, Ying, Lozanguiez, Yoany, Longley, Clifford, Greenberger, Lee M, Horak, Ivan D
Published in Bioconjugate chemistry (01.04.2008)
Published in Bioconjugate chemistry (01.04.2008)
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Journal Article
Multivalent peptidic linker enables identification of preferred sites of conjugation for a potent thialanstatin antibody drug conjugate
Puthenveetil, Sujiet, He, Haiyin, Loganzo, Frank, Musto, Sylvia, Teske, Jesse, Green, Michael, Tan, Xingzhi, Hosselet, Christine, Lucas, Judy, Tumey, L Nathan, Sapra, Puja, Subramanyam, Chakrapani, O'Donnell, Christopher J, Graziani, Edmund I
Published in PloS one (30.05.2017)
Published in PloS one (30.05.2017)
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Journal Article
Novel Delivery of SN38 Markedly Inhibits Tumor Growth in Xenografts, Including a Camptothecin-11–Refractory Model
SAPRA, Puja, HONG ZHAO, MEHLIG, Mary, MALABY, Jennifer, KRAFT, Patricia, LONGLEY, Clifford, GREENBERGER, Lee M, HORAK, Ivan D
Published in Clinical cancer research (15.03.2008)
Published in Clinical cancer research (15.03.2008)
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Gemtuzumab Ozogamicin (GO) Inclusion to Induction Chemotherapy Eliminates Leukemic Initiating Cells and Significantly Improves Survival in Mouse Models of Acute Myeloid Leukemia
Zhang, Cathy C, Yan, Zhengming, Pascual, Bernadette, Jackson-Fisher, Amy, Huang, Donghui Stephen, Zong, Qing, Elliott, Mark, Fan, Conglin, Huser, Nanni, Lee, Joseph, Sung, Matthew, Sapra, Puja
Published in Neoplasia (New York, N.Y.) (01.01.2018)
Published in Neoplasia (New York, N.Y.) (01.01.2018)
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Journal Article
Biodistribution and Targeting of Anti-5T4 Antibody-Drug Conjugate Using Fluorescence Molecular Tomography
Giddabasappa, Anand, Gupta, Vijay R, Norberg, Rand, Gupta, Parul, Spilker, Mary E, Wentland, Joann, Rago, Brian, Eswaraka, Jeetendra, Leal, Mauricio, Sapra, Puja
Published in Molecular cancer therapeutics (01.10.2016)
Published in Molecular cancer therapeutics (01.10.2016)
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Journal Article
Tumor Regression and Curability of Preclinical Neuroblastoma Models by PEGylated SN38 (EZN-2208), a Novel Topoisomerase I Inhibitor
PASTORINO, Fabio, LOI, Monica, SAPRA, Puja, BECHERINI, Pamela, CILLI, Michele, EMIONITE, Laura, RIBATTI, Domenico, GREENBERGER, Lee M, HORAK, Ivan D, PONZONI, Mirco
Published in Clinical cancer research (01.10.2010)
Published in Clinical cancer research (01.10.2010)
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Journal Article
Preclinical Development of an anti-5T4 Antibody–Drug Conjugate: Pharmacokinetics in Mice, Rats, and NHP and Tumor/Tissue Distribution in Mice
Leal, Mauricio, Wentland, JoAnn, Han, Xiaogang, Zhang, Yanhua, Rago, Brian, Duriga, Nicole, Spriggs, Franklin, Kadar, Eugene, Song, Wei, McNally, James, Shakey, Quazi, Lorello, Leslie, Lucas, Judy, Sapra, Puja
Published in Bioconjugate chemistry (18.11.2015)
Published in Bioconjugate chemistry (18.11.2015)
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Journal Article
Targeting and pharmacology of an anti-IL13Rα2 antibody and antibody-drug conjugate in a melanoma xenograft model
Gupta, Parul, Jiang, Ziyue Karen, Yang, Bing, Manzuk, Lisa, Rosfjord, Edward, Yao, Johnny, Lemon, Luanna, Noorbehesht, Kavon, David, John, Puthenveetil, Sujiet, Casavant, Jeffrey M, Muszynska, Elwira, Li, Fengping, Leal, Mauricio, Sapra, Puja, Giddabasappa, Anand
Published in mAbs (2021)
Published in mAbs (2021)
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Journal Article
On translation of antibody drug conjugates efficacy from mouse experimental tumors to the clinic: a PK/PD approach
Haddish-Berhane, Nahor, Shah, Dhaval K., Ma, Dangshe, Leal, Mauricio, Gerber, Hans-Peter, Sapra, Puja, Barton, Hugh A., Betts, Alison M.
Published in Journal of pharmacokinetics and pharmacodynamics (01.10.2013)
Published in Journal of pharmacokinetics and pharmacodynamics (01.10.2013)
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Journal Article
Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors
Root, Adam R, Guntas, Gurkan, Katragadda, Madan, Apgar, James R, Narula, Jatin, Chang, Chew Shun, Hanscom, Sara, McKenna, Matthew, Wade, Jason, Meade, Caryl, Ma, Weijun, Guo, Yongjing, Liu, Yan, Duan, Weili, Hendershot, Claire, King, Amy C, Zhang, Yan, Sousa, Eric, Tam, Amy, Benard, Susan, Yang, Han, Kelleher, Kerry, Jin, Fang, Piche-Nicholas, Nicole, Keating, Sinead E, Narciandi, Fernando, Lawrence-Henderson, Rosemary, Arai, Maya, Stochaj, Wayne R, Svenson, Kristine, Mosyak, Lidia, Lam, Khetemcnee, Francis, Christopher, Marquette, Kimberly, Wroblewska, Liliana, Zhu, H Lily, Sheehan, Alfredo Darmanin, LaVallie, Edward R, D'Antona, Aaron M, Betts, Alison, King, Lindsay, Rosfjord, Edward, Cunningham, Orla, Lin, Laura, Sapra, Puja, Tchistiakova, Lioudmila, Mathur, Divya, Bloom, Laird
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
Targeting the 5T4 oncofetal glycoprotein with an antibody drug conjugate (A1mcMMAF) improves survival in patient-derived xenograft models of acute lymphoblastic leukemia
McGinn, Owen J, Krishnan, Shekhar, Bourquin, Jean-Pierre, Sapra, Puja, Dempsey, Clare, Saha, Vaskar, Stern, Peter L
Published in Haematologica (Roma) (01.06.2017)
Published in Haematologica (Roma) (01.06.2017)
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