A hypermorphic missense mutation in PLCG2, encoding phospholipase Cγ2, causes a dominantly inherited autoinflammatory disease with immunodeficiency
Zhou, Qing, Lee, Geun-Shik, Brady, Jillian, Datta, Shrimati, Katan, Matilda, Sheikh, Afzal, Martins, Marta S, Bunney, Tom D, Santich, Brian H, Moir, Susan, Kuhns, Douglas B, Long Priel, Debra A, Ombrello, Amanda, Stone, Deborah, Ombrello, Michael J, Khan, Javed, Milner, Joshua D, Kastner, Daniel L, Aksentijevich, Ivona
Published in American journal of human genetics (05.10.2012)
Published in American journal of human genetics (05.10.2012)
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Journal Article
Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals
Kardava, Lela, Moir, Susan, Shah, Naisha, Wang, Wei, Wilson, Richard, Buckner, Clarisa M, Santich, Brian H, Kim, Leo J Y, Spurlin, Emily E, Nelson, Amy K, Wheatley, Adam K, Harvey, Christopher J, McDermott, Adrian B, Wucherpfennig, Kai W, Chun, Tae-Wook, Tsang, John S, Li, Yuxing, Fauci, Anthony S
Published in The Journal of clinical investigation (01.07.2014)
Published in The Journal of clinical investigation (01.07.2014)
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Journal Article
Heterodimerization of T cell engaging bispecific antibodies to enhance specificity against pancreatic ductal adenocarcinoma
Long, Alan W, Xu, Hong, Santich, Brian H, Guo, Hongfen, Hoseini, Sayed Shahabuddin, de Stanchina, Elisa, Cheung, Nai-Kong V
Published in Journal of hematology and oncology (23.04.2024)
Published in Journal of hematology and oncology (23.04.2024)
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Journal Article
Impaired B cell immunity in acute myeloid leukemia patients after chemotherapy
Goswami, Meghali, Prince, Gabrielle, Biancotto, Angelique, Moir, Susan, Kardava, Lela, Santich, Brian H, Cheung, Foo, Kotliarov, Yuri, Chen, Jinguo, Shi, Rongye, Zhou, Huizhi, Golding, Hana, Manischewitz, Jody, King, Lisa, Kunz, Lauren M, Noonan, Kimberly, Borrello, Ivan M, Smith, B Douglas, Hourigan, Christopher S
Published in Journal of translational medicine (10.07.2017)
Published in Journal of translational medicine (10.07.2017)
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Journal Article
Editorial: Bispecific Antibodies for T-Cell Based Immunotherapy
Santich, Brian H, Cheung, Nai-Kong V, Klein, Christian
Published in Frontiers in oncology (09.12.2020)
Published in Frontiers in oncology (09.12.2020)
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Journal Article
TCR-mimic bispecific antibodies targeting LMP2A show potent activity against EBV malignancies
Ahmed, Mahiuddin, Lopez-Albaitero, Andres, Pankov, Dmitry, Santich, Brian H, Liu, Hong, Yan, Su, Xiang, Jingyi, Wang, Pei, Hasan, Aisha N, Selvakumar, Annamalai, O'Reilly, Richard J, Liu, Cheng, Cheung, Nai-Kong V
Published in JCI insight (22.02.2018)
Published in JCI insight (22.02.2018)
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A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy
Santich, Brian H, Cheal, Sarah M, Ahmed, Mahiuddin, McDevitt, Michael R, Ouerfelli, Ouathek, Yang, Guangbin, Veach, Darren R, Fung, Edward K, Patel, Mitesh, Burnes Vargas, Daniela, Malik, Aiza A, Guo, Hong-Fen, Zanzonico, Pat B, Monette, Sebastien, Michel, Adam O, Rudin, Charles M, Larson, Steven M, Cheung, Nai K
Published in Clinical cancer research (15.01.2021)
Published in Clinical cancer research (15.01.2021)
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Journal Article
Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection
Cubas, Rafael, van Grevenynghe, Julien, Wills, Saintedym, Kardava, Lela, Santich, Brian H, Buckner, Clarisa M, Muir, Roshell, Tardif, Virginie, Nichols, Carmen, Procopio, Francesco, He, Zhong, Metcalf, Talibah, Ghneim, Khader, Locci, Michela, Ancuta, Petronella, Routy, Jean-Pierre, Trautmann, Lydie, Li, Yuxing, McDermott, Adrian B, Koup, Rick A, Petrovas, Constantinos, Migueles, Steven A, Connors, Mark, Tomaras, Georgia D, Moir, Susan, Crotty, Shane, Haddad, Elias K
Published in The Journal of immunology (1950) (15.12.2015)
Published in The Journal of immunology (1950) (15.12.2015)
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Journal Article
Intraperitoneal Pretargeted Radioimmunotherapy for Colorectal Peritoneal Carcinomatosis
Chandler, Christopher S, Bell, Meghan M, Chung, Sebastian K, Veach, Darren R, Fung, Edward K, Punzalan, Blesida, Burnes Vargas, Daniela, Patel, Mitesh, Xu, Hong, Guo, Hong-Fen, Santich, Brian H, Zanzonico, Pat B, Monette, Sébastien, Nash, Garrett M, Cercek, Andrea, Jungbluth, Achim, Pandit-Taskar, Neeta, Cheung, Nai Kong V, Larson, Steven M, Cheal, Sarah M
Published in Molecular cancer therapeutics (01.01.2022)
Published in Molecular cancer therapeutics (01.01.2022)
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Journal Article
Engineered Cells as a Test Platform for Radiohaptens in Pretargeted Imaging and Radioimmunotherapy Applications
Dacek, Megan M, Veach, Darren R, Cheal, Sarah M, Carter, Lukas M, McDevitt, Michael R, Punzalan, Blesida, Burnes Vargas, Daniela, Kubik, Thomas Z, Monette, Sebastien, Santich, Brian H, Yang, Guangbin, Ouerfelli, Ouathek, Kesner, Adam L, Cheung, Nai-Kong V, Scheinberg, David A, Larson, Steven M, Krebs, Simone
Published in Bioconjugate chemistry (21.04.2021)
Published in Bioconjugate chemistry (21.04.2021)
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Journal Article
Successful engineering of a highly potent single-chain variable-fragment (scFv) bispecific antibody to target disialoganglioside (GD2) positive tumors
Cheng, Ming, Santich, Brian H., Xu, Hong, Ahmed, Mahiuddin, Huse, Morgan, Cheung, Nai-Kong V.
Published in Oncoimmunology (02.06.2016)
Published in Oncoimmunology (02.06.2016)
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Journal Article
Gravesʹ disease as immune reconstitution disease in HIV-positive patients is associated with naive and primary thymic emigrant CD4+ T-cell recovery
SHEIKH, Virginia, DERSIMONIAN, Rebecca, MOIR, Susan, SERETI, Irini, RICHTERMAN, Aaron G, PORTER, Brian O, NATARAJAN, Ven, BURBELO, Peter D, RUPERT, Adam, SANTICH, Brian H, KARDAVA, Lela, MICAN, JoAnn M
Published in AIDS (London) (02.01.2014)
Published in AIDS (London) (02.01.2014)
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Generation of TCR-Like Antibodies Using Phage Display
Santich, Brian H, Liu, Hong, Liu, Cheng, Cheung, Nai-Kong V
Published in Methods in molecular biology (Clifton, N.J.) (2015)
Published in Methods in molecular biology (Clifton, N.J.) (2015)
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Journal Article
Humans with chronic granulomatous disease maintain humoral immunologic memory despite low frequencies of circulating memory B cells
Moir, Susan, De Ravin, Suk See, Santich, Brian H., Kim, Jin Young, Posada, Jacqueline G., Ho, Jason, Buckner, Clarisa M., Wang, Wei, Kardava, Lela, Garofalo, Mary, Marciano, Beatriz E., Manischewitz, Jody, King, Lisa R., Khurana, Surender, Chun, Tae-Wook, Golding, Hana, Fauci, Anthony S., Malech, Harry L.
Published in Blood (06.12.2012)
Published in Blood (06.12.2012)
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Journal Article
Bone marrow plasma cells are a primary source of serum HIV-1-specific antibodies in chronically infected individuals
Montezuma-Rusca, Jairo M, Moir, Susan, Kardava, Lela, Buckner, Clarisa M, Louie, Aaron, Kim, Leo J Y, Santich, Brian H, Wang, Wei, Fankuchen, Olivia R, Diaz, Gabriella, Daub, Janine R, Rosenzweig, Sergio D, Chun, Tae-Wook, Li, Yuxing, Braylan, Raul C, Calvo, Katherine R, Fauci, Anthony S
Published in The Journal of immunology (1950) (15.03.2015)
Published in The Journal of immunology (1950) (15.03.2015)
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Alpha radioimmunotherapy using 225 Ac-proteus-DOTA for solid tumors - safety at curative doses
Cheal, Sarah M, McDevitt, Michael R, Santich, Brian H, Patel, Mitesh, Yang, Guangbin, Fung, Edward K, Veach, Darren R, Bell, Meghan, Ahad, Afruja, Vargas, Daniela Burnes, Punzalan, Blesida, Pillarsetty, Naga Vara Kishore, Xu, Hong, Guo, Hong-Fen, Monette, Sébastien, Michel, Adam O, Piersigilli, Alessandra, Scheinberg, David A, Ouerfelli, Ouathek, Cheung, Nai-Kong V, Larson, Steven M
Published in Theranostics (2020)
Published in Theranostics (2020)
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