Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder
Edmondson, Scott D, Zhu, Cheng, Kar, Nam Fung, Di Salvo, Jerry, Nagabukuro, Hiroshi, Sacre-Salem, Beatrice, Dingley, Karen, Berger, Richard, Goble, Stephen D, Morriello, Gregori, Harper, Bart, Moyes, Christopher R, Shen, Dong-Ming, Wang, Liping, Ball, Richard, Fitzmaurice, Aileen, Frenkl, Tara, Gichuru, Loise N, Ha, Sookhee, Hurley, Amanda L, Jochnowitz, Nina, Levorse, Dorothy, Mistry, Shruty, Miller, Randy R, Ormes, James, Salituro, Gino M, Sanfiz, Anthony, Stevenson, Andra S, Villa, Katherine, Zamlynny, Beata, Green, Stuart, Struthers, Mary, Weber, Ann E
Published in Journal of medicinal chemistry (28.01.2016)
Published in Journal of medicinal chemistry (28.01.2016)
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Design, Synthesis, and Evaluation of Conformationally Restricted Acetanilides as Potent and Selective β3 Adrenergic Receptor Agonists for the Treatment of Overactive Bladder
Moyes, Christopher R, Berger, Richard, Goble, Stephen D, Harper, Bart, Shen, Dong-Ming, Wang, Liping, Bansal, Alka, Brown, Patricia N, Chen, Airu S, Dingley, Karen H, Di Salvo, Jerry, Fitzmaurice, Aileen, Gichuru, Loise N, Hurley, Amanda L, Jochnowitz, Nina, Miller, Randall R, Mistry, Shruty, Nagabukuro, Hiroshi, Salituro, Gino M, Sanfiz, Anthony, Stevenson, Andra S, Villa, Katherine, Zamlynny, Beata, Struthers, Mary, Weber, Ann E, Edmondson, Scott D
Published in Journal of medicinal chemistry (27.02.2014)
Published in Journal of medicinal chemistry (27.02.2014)
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Tyrosine Sulfation of CCR5 N-Terminal Peptide by Tyrosylprotein Sulfotransferases 1 and 2 Follows a Discrete Pattern and Temporal Sequence
Seibert, Christoph, Cadene, Martine, Sanfiz, Anthony, Chait, Brian T., Sakmar, Thomas P.
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (20.08.2002)
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Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human β₃ adrenergic receptor agonists
Morriello, Gregori J, Wendt, Harvey R, Bansal, Alka, Salvo, Jerry Di, Feighner, Scott, He, Jiafang, Hurley, Amanda L, Hreniuk, Donna L, Salituro, Gino M, Reddy, Marat Vijay, Galloway, Sheila M, McGettigan, Katherine K, Laws, George, McKnight, Crystal, Doss, George A, Tsou, Nancy N, Black, Regina M, Morris, Judy, Ball, Richard G, Sanfiz, Anthony T, Streckfuss, Eric, Struthers, Mary, Edmondson, Scott D
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Development and validation of an in vitro 3D model of NASH with severe fibrotic phenotype
Mukherjee, Sumanta, Zhelnin, Leonid, Sanfiz, Anthony, Pan, Jie, Li, Zhuyin, Yarde, Melissa, McCarty, Jean, Jarai, Gabor
Published in American journal of translational research (01.01.2019)
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Published in American journal of translational research (01.01.2019)
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Discovery of Vibegron: A Potent and Selective beta(3) Adrenergic Receptor Agonist for the Treatment of Overactive Bladder
Edmondson, Scott D., Zhu, Cheng, Kar, Nam Fung, Di Salvo, Jerry, Nagabukuro, Hiroshi, Sacre-Salem, Beatrice, Dingley, Karen, Berger, Richard, Goble, Stephen D., Morriello, Gregori, Harper, Bart, Moyes, Christopher R., Shen, Dong-Ming, Wang, Liping, Ball, Richard, Fitzmaurice, Aileen, Frenkl, Tara, Gichuru, Loise N., Ha, Sookhee, Hurley, Amanda L., Jochnowitz, Nina, Levorse, Dorothy, Mistry, Shruty, Miller, Randy R., Ormes, James, Salituro, Gino M., Sanfiz, Anthony, Stevenson, Andra S., Villa, Katherine, Zamlynny, Beata, Green, Stuart, Struthers, Mary, Weber, Ann E.
Published in Journal of medicinal chemistry (28.01.2016)
Published in Journal of medicinal chemistry (28.01.2016)
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749 COLLAGEN NEO-EPITOPE RATIOS ARE ASSOCIATED WITH SIGNIFICANT WEIGHT LOSS, AND IMPROVEMENT OF NON-INVASIVE TEST (NIT) IN PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH)
Younossi, Zobair M., Karrar, Azza, Stepanova, Maria, Lam, Brian P., Rajput, Bijal, Felix, Sean C., Jeffers, Thomas, Hellings, Samuel, Brown, Elizabeth, Sanfiz, Anthony, Nielsen, Mette Juul, Gudmann, Natasja, Leeming, Diana J., Spires, Thomas E., Yarde, Melissa, Luo, Yi, Zhelnin, Leonid, Cvijic, Mary Ellen, Charles, Edgar, Mukherjee, Sumanta, Zhao, Lei, Karsdal, Morten Asser, Gordon, David, Nader, Fatema, Goodman, Zachary
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2020)
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SAT-335-A simple biomarker panel predictive of advanced fibrosis in patients with non-alcoholic steatohepatitis
Younossi, Zobair, Karrar, Azza, Stepanova, Maria, Lam, Brian, Felix, Sean, Jeffers, Thomas, Hellings, Samuel, Brown, Elizabeth, Spires, Thomas, Yarde, Melissa, Luo, Yi, Sanfiz, Anthony, Zhelnin, Leonid, Jarai, Gabor, Cvijic, Mary Ellen, Charles, Edgar, Mukherjee, Sumanta, Zhao, Lei, Gordon, David, Nader, Fatema, Goodman, Zachary
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Journal Article
Design, Synthesis, and Evaluation of Conformationally Restricted Acetanilides as Potent and Selective beta(3) Adrenergic Receptor Agonists for the Treatment of Overactive Bladder
Moyes, Christopher R., Berger, Richard, Goble, Stephen D., Harper, Bart, Shen, Dong-Ming, Wang, Liping, Bansal, Alka, Brown, Patricia N., Chen, Airu S., Dingley, Karen H., Di Salvo, Jerry, Fitzmaurice, Aileen, Gichuru, Loise N., Hurley, Amanda L., Jochnowitz, Nina, Miller, Randall R., Mistry, Shruty, Nagabukuro, Hiroshi, Salituro, Gino M., Sanfiz, Anthony, Stevenson, Andra S., Villa, Katherine, Zamlynny, Beata, Struthers, Mary, Weber, Ann E., Edmondson, Scott D.
Published in Journal of medicinal chemistry (27.02.2014)
Published in Journal of medicinal chemistry (27.02.2014)
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Journal Article
Discovery of Vibegron: A Potent and Selective β 3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder
Edmondson, Scott D., Zhu, Cheng, Kar, Nam Fung, Di Salvo, Jerry, Nagabukuro, Hiroshi, Sacre-Salem, Beatrice, Dingley, Karen, Berger, Richard, Goble, Stephen D., Morriello, Gregori, Harper, Bart, Moyes, Christopher R., Shen, Dong-Ming, Wang, Liping, Ball, Richard, Fitzmaurice, Aileen, Frenkl, Tara, Gichuru, Loise N., Ha, Sookhee, Hurley, Amanda L., Jochnowitz, Nina, Levorse, Dorothy, Mistry, Shruty, Miller, Randy R., Ormes, James, Salituro, Gino M., Sanfiz, Anthony, Stevenson, Andra S., Villa, Katherine, Zamlynny, Beata, Green, Stuart, Struthers, Mary, Weber, Ann E.
Published in Journal of medicinal chemistry (28.01.2016)
Published in Journal of medicinal chemistry (28.01.2016)
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Journal Article
Design, Synthesis, and Evaluation of Conformationally Restricted Acetanilides as Potent and Selective β 3 Adrenergic Receptor Agonists for the Treatment of Overactive Bladder
Moyes, Christopher R., Berger, Richard, Goble, Stephen D., Harper, Bart, Shen, Dong-Ming, Wang, Liping, Bansal, Alka, Brown, Patricia N., Chen, Airu S., Dingley, Karen H., Di Salvo, Jerry, Fitzmaurice, Aileen, Gichuru, Loise N., Hurley, Amanda L., Jochnowitz, Nina, Miller, Randall R., Mistry, Shruty, Nagabukuro, Hiroshi, Salituro, Gino M., Sanfiz, Anthony, Stevenson, Andra S., Villa, Katherine, Zamlynny, Beata, Struthers, Mary, Weber, Ann E., Edmondson, Scott D.
Published in Journal of medicinal chemistry (27.02.2014)
Published in Journal of medicinal chemistry (27.02.2014)
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Journal Article
Regulation of PTEN binding to MAGI-2 by two putative phosphorylation sites at threonine 382 and 383
TOLKACHEVA, Tatyana, BODDAPATI, Manoranjan, SANFIZ, Anthony, TSUCHIDA, Kunihiro, KIMMELMAN, Alec C, CHAN, Andrew M-L
Published in Cancer research (Chicago, Ill.) (01.07.2001)
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Published in Cancer research (Chicago, Ill.) (01.07.2001)
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Heterocyclic acetamide and benzamide derivatives as potent and selective β3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles
GOBLE, Stephen D, LIPING WANG, HURLEY, Amanda, HRENIUK, Donna, PARMEE, Emma, ROBBINS, Michael, SALITURO, Gino, SANFIZ, Anthony, STRECKFUSS, Eric, WATKINS, Eloisa, WEBER, Ann E, STRUTHERS, Mary, LULU HOWELL, K, EDMONDSON, Scott D, BANSAL, Alka, BERGER, Richard, BROCKUNIER, Linda, DISALVO, Jerry, FEIGHNER, Scott, HARPER, Bart, JIAFANG HE
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
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Journal Article
Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human beta sub(3 adrenergic receptor agonists)
Morriello, Gregori J, Wendt, Harvey R, Bansal, Alka, Di Salvo, Jerry, Feighner, Scott, He, Jiafang, Hurley, Amanda L, Hreniuk, Donna L, Salituro, Gino M, Reddy, Marat Vijay, Galloway, Sheila M, McGettigan, Katherine K, Laws, George, McKnight, Crystal, Doss, George A, Tsou, Nancy N, Black, Regina M, Morris, Judy, Ball, Richard G, Sanfiz, Anthony T, Streckfuss, Eric, Struthers, Mary, Edmondson, Scott D
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Journal Article
Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human β 3 adrenergic receptor agonists
Morriello, Gregori J., Wendt, Harvey R., Bansal, Alka, Salvo, Jerry Di, Feighner, Scott, He, Jiafang, Hurley, Amanda L., Hreniuk, Donna L., Salituro, Gino M., Reddy, Marat Vijay, Galloway, Sheila M., McGettigan, Katherine K., Laws, George, McKnight, Crystal, Doss, George A., Tsou, Nancy N., Black, Regina M., Morris, Judy, Ball, Richard G., Sanfiz, Anthony T., Streckfuss, Eric, Struthers, Mary, Edmondson, Scott D.
Published in Bioorganic & medicinal chemistry letters (2011)
Published in Bioorganic & medicinal chemistry letters (2011)
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Journal Article
Heterocyclic acetamide and benzamide derivatives as potent and selective b sub(3)-adrenergic receptor agonists with improved rodent pharmacokinetic profiles
Goble, Stephen D, Wang, Liping, Howell, KLulu, Bansal, Alka, Berger, Richard, Brockunier, Linda, DiSalvo, Jerry, Feighner, Scott, Harper, Bart, He, Jiafang, Hurley, Amanda, Hreniuk, Donna, Parmee, Emma, Robbins, Michael, Salituro, Gino, Sanfiz, Anthony, Streckfuss, Eric, Watkins, Eloisa, Weber, Ann E, Struthers, Mary, Edmondson, Scott D
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
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Journal Article
Heterocyclic acetamide and benzamide derivatives as potent and selective β 3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles
Goble, Stephen D., Wang, Liping, Howell, K. Lulu, Bansal, Alka, Berger, Richard, Brockunier, Linda, DiSalvo, Jerry, Feighner, Scott, Harper, Bart, He, Jiafang, Hurley, Amanda, Hreniuk, Donna, Parmee, Emma, Robbins, Michael, Salituro, Gino, Sanfiz, Anthony, Streckfuss, Eric, Watkins, Eloisa, Weber, Ann E., Struthers, Mary, Edmondson, Scott D.
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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Journal Article
Heterocyclic acetamide and benzamide derivatives as potent and selective beta3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles
Goble, Stephen D, Wang, Liping, Howell, K Lulu, Bansal, Alka, Berger, Richard, Brockunier, Linda, DiSalvo, Jerry, Feighner, Scott, Harper, Bart, He, Jiafang, Hurley, Amanda, Hreniuk, Donna, Parmee, Emma, Robbins, Michael, Salituro, Gino, Sanfiz, Anthony, Streckfuss, Eric, Watkins, Eloisa, Weber, Ann E, Struthers, Mary, Edmondson, Scott D
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
Published in Bioorganic & medicinal chemistry letters (15.03.2010)
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Journal Article