A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015): A Potential Treatment for Spinal Muscular Atrophy
Barrett, Doreen, Bilic, Sanela, Chyung, Yung, Cote, Shaun M., Iarrobino, Ryan, Kacena, Katherine, Kalra, Ashish, Long, Kimberly, Nomikos, George, Place, Amy, Still, James Gordon, Vrishabhendra, Leela
Published in Advances in therapy (01.06.2021)
Published in Advances in therapy (01.06.2021)
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Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclones
Denisenko, Elena, de Kock, Leanne, Tan, Adeline, Beasley, Aaron B., Beilin, Maria, Jones, Matthew E., Hou, Rui, Muirí, Dáithí Ó, Bilic, Sanela, Mohan, G. Raj K. A., Salfinger, Stuart, Fox, Simon, Hmon, Khaing P. W., Yeow, Yen, Kim, Youngmi, John, Rhea, Gilderman, Tami S., Killingbeck, Emily, Gray, Elin S., Cohen, Paul A., Yu, Yu, Forrest, Alistair R. R.
Published in Nature communications (03.04.2024)
Published in Nature communications (03.04.2024)
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Bioanalysis of antibody-drug conjugates: American Association of Pharmaceutical Scientists Antibody-Drug Conjugate Working Group position paper
Gorovits, Boris, Alley, Stephen C, Bilic, Sanela, Booth, Brian, Kaur, Surinder, Oldfield, Phillip, Purushothama, Shobha, Rao, Chetana, Shord, Stacy, Siguenza, Patricia
Published in Bioanalysis (01.05.2013)
Published in Bioanalysis (01.05.2013)
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Journal Article
Nonclinical Development of SRK-181: An Anti-Latent TGFβ1 Monoclonal Antibody for the Treatment of Locally Advanced or Metastatic Solid Tumors
Welsh, Brian T., Faucette, Ryan, Bilic, Sanela, Martin, Constance J., Schürpf, Thomas, Chen, David, Nicholls, Samantha, Lansita, Janice, Kalra, Ashish
Published in International journal of toxicology (01.05.2021)
Published in International journal of toxicology (01.05.2021)
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Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies
Ettenberg, Seth A., Charlat, Olga, Daley, Michael P., Liu, Shanming, Vincent, Karen J., Stuart, Darrin D., Schuller, Alwin G., Yuan, Jing, Ospina, Beatriz, Green, John, Yu, Qunyan, Walsh, Renee, Li, Sharon, Schmitz, Rita, Heine, Holger, Bilic, Sanela, Ostrom, Lance, Mosher, Rebecca, Hartlepp, K. Felix, Zhu, Zhenping, Fawell, Stephen, Yao, Yung-Mae, Stover, David, Finan, Peter M., Porter, Jeffery A., Sellers, William R., Klagge, Ingo M., Cong, Feng, Nusse, Roeland
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (31.08.2010)
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Transcriptomic analysis of patient plasma reveals circulating miR200c as a potential biomarker for high-grade serous ovarian cancer
Hannan, Natalie J., Cohen, Paul A., Beard, Sally, Bilic, Sanela, Zhang, Bonnie, Tong, Stephen, Whitehead, Clare, Hui, Lisa
Published in Gynecologic oncology reports (01.02.2022)
Published in Gynecologic oncology reports (01.02.2022)
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801 PRIME™ IL-15 (RPTR-147): Preliminary clinical results and biomarker analysis from a first-in-human Phase 1 study of IL-15 loaded peripherally-derived autologous T cell therapy in solid tumor patients
Hamilton, Erika, Nikiforow, Sarah, Bardwell, Philip, McInnis, Christine, Zhang, Jeffrey, Blumenschein, George, Cristea, Mihaela, Osman, Keren, Shields, Anthony, Motta, Marlyane, Bilic, Sanela, Schoenborn-Kellenberger, Oliver, Rakestraw, James, Carey, Shawn, Geretti, Elena, Sauer, Karsten, Harris, Tim, Maniar, Tap, Hewes, Becker, Andresen, Thomas, Fitzgerald, Jonathan, Kluger, Harriet
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Compartmental Pharmacokinetic Analysis of Oral Amprenavir with Secondary Peaks
OKUSANYA, Olanrewaju, FORREST, Alan, DIFRANCESCO, Robin, BILIC, Sanela, ROSENKRANZ, Susan, PARA, Michael F, ADAMS, Elizabeth, YARASHESKI, Kevin E, REICHMAN, Richard C, MORSE, Gene D
Published in Antimicrobial Agents and Chemotherapy (01.05.2007)
Published in Antimicrobial Agents and Chemotherapy (01.05.2007)
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392-P: Phase 1, Randomized, Controlled Trial of GFB-024, a Once-Monthly CB1 Inverse Agonist, in Healthy Overweight and Obese Participants and in Participants with Type 2 Diabetes Mellitus
GAICH, GREGORY, BILIC, SANELA, DAGON, YOSSI, GUSTAFSON, THOMAS, LAWLER, JOHN, JOHNSON, LESLIE, RUDOLPH-OWEN, LORI
Published in Diabetes (New York, N.Y.) (01.06.2022)
Published in Diabetes (New York, N.Y.) (01.06.2022)
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A Phase IB multicentre dose‐determination study of BHQ880 in combination with anti‐myeloma therapy and zoledronic acid in patients with relapsed or refractory multiple myeloma and prior skeletal‐related events
Iyer, Swaminathan P., Beck, Joseph Taddeus, Stewart, A. Keith, Shah, Jatin, Kelly, Kevin R., Isaacs, Randi, Bilic, Sanela, Sen, Suman, Munshi, Nikhil C.
Published in British journal of haematology (01.11.2014)
Published in British journal of haematology (01.11.2014)
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Journal Article
Unexpected hepatotoxicity in a phase I study of TAS266, a novel tetravalent agonistic Nanobody® targeting the DR5 receptor
Papadopoulos, Kyriakos P., Isaacs, Randi, Bilic, Sanela, Kentsch, Kerstin, Huet, Heather A., Hofmann, Matthias, Rasco, Drew, Kundamal, Nicole, Tang, Zhongwhen, Cooksey, Jennifer, Mahipal, Amit
Published in Cancer chemotherapy and pharmacology (01.05.2015)
Published in Cancer chemotherapy and pharmacology (01.05.2015)
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MYTX-011 in patients with previously treated locally advanced or metastatic NSCLC: Initial dose escalation results in the phase 1 KisMET-01 study
Johnson, Melissa Lynne, Burns, Timothy F., Thompson, Jonathan Robert, Spira, Alexander I., Alexander, Mariam, Blumenschein, George R., Michalski, Joel, Bilic, Sanela, Teh, Aza, Lai, Katharine C., McGann, Shane, Chalk, Helen, Haystrand, Lisa, Wu, Ting-Hui, Gallant, Gilles, Heist, Rebecca Suk
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Prognostic gene expression signature for high-grade serous ovarian cancer
Intermaggio, M.P., Leong, H.S., Chen, S., Elatre, W., Gilks, B., Volchek, M., Wang, C., Mackenzie, R., George, J., Bowtell, D., Chenevix-Trench, G., Green, A., Gertig, D., Fereday, S., Moore, S., Hung, J., Harrap, K., Malt, M., Robertson, R., Maidens, J., Jayde, V., Mamers, P., Schmidt, T., Ball, C., Bilic, Sanela, Stuart-Harris, R., Clingan, P., Glasgow, A., Shannon, J., Young, B., Robertson, G., Carter, J., Dalrymple, C., Russell, P., Links, M., Jaworski, R., Crandon, A., Horwood, K., Obermair, A., Wyld, D., Davy, M., Dodd, T., Healy, T., Pittman, K., Henderson, D., Pierdes, J., Brown, B., Hyde, S., Healy, D., McNealage, J., Simpson, I., Fox, S., Lade, S., Loughrey, M., Neesham, D., Bell, R., Ng, L.F., Whiteman, D., Fereday, S., Steed, H., Koziak, J.M., Goranova, T., Silva De Silva, D., Ramón y Cajal, T., García-Donas, J., Rodriguez, G.C., Harris, H.R., Greene, C.S., Zelaya, R.A., Sinn, P., Menkiszak, J., Pearce, C.L., Rhenius, V., Piskorz, A.M., Sharma, R., Johnatty, S.E., Larson, M.C., Luk, H., Hernandez, B.Y., Thompson, P.J., Sherman, M.E., Bodelon, C., Lewsley, L.A., Banerjee, S.N., Stronach, E.A., Haluska, P., Ray-Coquard, I., Winterhoff, B., Slamon, D., Levine, D.A., Menon, U., Goodman, M.T., Schildkraut, J.M., Brown, R., Berchuck, A., Chenevix-Trench, G., deFazio, A., Beeghly-Fadiel, A., Fasching, P.A., Orsulic, S.
Published in Annals of oncology (01.09.2020)
Published in Annals of oncology (01.09.2020)
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8 A single arm pilot observational study to evaluate the safety and feasibility of a pre-operative very low calorie diet in severely obese patients with endometrial cancer
Ayres, Chloe, Burbidge, Hanna, Garrett, Jayna-Lee, Mohan, Ganendra Raj, Leung, Yee, Jeffares, Stephanie, Bilic, Sanela, Cohen, Paul A
Published in International journal of gynecological cancer (10.03.2024)
Published in International journal of gynecological cancer (10.03.2024)
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Dose expansion results of the bifunctional EGFR/TGFβ inhibitor BCA101 with pembrolizumab in patients with recurrent, metastatic head and neck squamous cell carcinoma
Hanna, Glenn J., Kaczmar, John M., Zandberg, Dan Paul, Wong, Deborah J.L., Yilmaz, Emrullah, Sherman, Eric Jeffrey, Hernando-Calvo, Alberto, Sacco, Assuntina G., Chung, Christine H., Bohr, David, Reiners, Ralf, Salazar, Rachel, Gharakhani, Elham, Bilic, Sanela, Muzaffar, Jameel
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Initial results of dose finding in a first-in-human phase 1 study of a novel Claudin 6 (CLDN6) targeted antibody drug conjugate (ADC) TORL-1-23 in patients with advanced solid tumors
Konecny, Gottfried E., Wahner Hendrickson, Andrea Elisabeth, Winterhoff, Boris, Chander, Cinthiya, Bilic, Sanela, Davenport, Simon, Chung, Adrine, Miller, Lei-Lani, Press, Michael F., Letrent, Stephen P., Slamon, Dennis J.
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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PR062/#686 First-in-human phase 1 study of torl-1–23, a novel claudin 6 (CLDN6) targeted antibody drug conjugate (ADC) in patients with ovarian cancer
Konecny, Gottfried, Hendrickson, Andrea Wahner, Winterhoff, Boris, Chander, Cinthiya, Bilic, Sanela, Davenport, Simon, Chung, Adrine, Miller, Lei-Lani, Press, Michael, Letrent, Stephen, Slamon, Dennis
Published in International journal of gynecological cancer (07.11.2023)
Published in International journal of gynecological cancer (07.11.2023)
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Safety and Efficacy of Apitegromab in Patients With Spinal Muscular Atrophy Types 2 and 3: The Phase 2 TOPAZ Study
Crawford, Thomas O, Darras, Basil T, Day, John W, Dunaway Young, Sally, Duong, Tina, Nelson, Leslie L, Barrett, Doreen, Song, Guochen, Bilic, Sanela, Cote, Shaun, Sadanowicz, Mara, Iarrobino, Ryan, Xu, Tiina J, O'Neil, Janet, Rossello, José, Place, Amy, Kertesz, Nathalie, Nomikos, George, Chyung, Yung
Published in Neurology (12.03.2024)
Published in Neurology (12.03.2024)
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Safety and Efficacy of Apitegromab in Patients With Spinal Muscular Atrophy Types 2 and 3: The Phase 2 TOPAZ Study
Published in Neurology
(09.07.2024)
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