Targeting MYC dependence in cancer by inhibiting BET bromodomains
Mertz, Jennifer A, Conery, Andrew R, Bryant, Barbara M, Sandy, Peter, Balasubramanian, Srividya, Mele, Deanna A, Bergeron, Louise, Sims, Robert J., III
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2011)
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Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials
Albrecht, Brian K, Gehling, Victor S, Hewitt, Michael C, Vaswani, Rishi G, Côté, Alexandre, Leblanc, Yves, Nasveschuk, Christopher G, Bellon, Steve, Bergeron, Louise, Campbell, Robert, Cantone, Nico, Cooper, Michael R, Cummings, Richard T, Jayaram, Hariharan, Joshi, Shivangi, Mertz, Jennifer A, Neiss, Adrianne, Normant, Emmanuel, O’Meara, Michael, Pardo, Eneida, Poy, Florence, Sandy, Peter, Supko, Jeffrey, Sims, Robert J, Harmange, Jean-Christophe, Taylor, Alexander M, Audia, James E
Published in Journal of medicinal chemistry (25.02.2016)
Published in Journal of medicinal chemistry (25.02.2016)
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Journal Article
Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors
Ceribelli, Michele, Kelly, Priscilla N., Shaffer, Arthur L., Wright, George W., Xiao, Wenming, Yang, Yibin, Griner, Lesley A. Mathews, Guha, Rajarshi, Shinn, Paul, Keller, Jonathan M., Liu, Dongbo, Patel, Paresma R., Ferrer, Marc, Joshi, Shivangi, Nerle, Sujata, Sandy, Peter, Normant, Emmanuel, Thomas, Craig J., Staudt, Louis M.
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2014)
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Journal Article
Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells
Scholl, Claudia, Fröhling, Stefan, Dunn, Ian F., Schinzel, Anna C., Barbie, David A., Kim, So Young, Silver, Serena J., Tamayo, Pablo, Wadlow, Raymond C., Ramaswamy, Sridhar, Döhner, Konstanze, Bullinger, Lars, Sandy, Peter, Boehm, Jesse S., Root, David E., Jacks, Tyler, Hahn, William C., Gilliland, D. Gary
Published in Cell (29.05.2009)
Published in Cell (29.05.2009)
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Journal Article
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
Conery, Andrew R, Centore, Richard C, Neiss, Adrianne, Keller, Patricia J, Joshi, Shivangi, Spillane, Kerry L, Sandy, Peter, Hatton, Charlie, Pardo, Eneida, Zawadzke, Laura, Bommi-Reddy, Archana, Gascoigne, Karen E, Bryant, Barbara M, Mertz, Jennifer A, Sims, Robert J
Published in eLife (05.01.2016)
Published in eLife (05.01.2016)
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Journal Article
Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance
Crawford, Terry D., Vartanian, Steffan, Côté, Alexandre, Bellon, Steve, Duplessis, Martin, Flynn, E. Megan, Hewitt, Michael, Huang, Hon-Ren, Kiefer, James R., Murray, Jeremy, Nasveschuk, Christopher G., Pardo, Eneida, Romero, F. Anthony, Sandy, Peter, Tang, Yong, Taylor, Alexander M., Tsui, Vickie, Wang, Jian, Wang, Shumei, Zawadzke, Laura, Albrecht, Brian K., Magnuson, Steven R., Cochran, Andrea G., Stokoe, David
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
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Journal Article
Paramedic students' confidence and satisfaction with clinical simulations of an emergency medical care programme in South Africa: A cross-sectional study
Sandy, Peter T, Meyer, John T, Oduniyi, Oluwaseun S, Mavhandu-Mudzusi, Azwihangwisi H
Published in Health SA = SA Gesondheid (2021)
Published in Health SA = SA Gesondheid (2021)
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Journal Article
Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors
Gehling, Victor S, Hewitt, Michael C, Vaswani, Rishi G, Leblanc, Yves, Côté, Alexandre, Nasveschuk, Christopher G, Taylor, Alexander M, Harmange, Jean-Christophe, Audia, James E, Pardo, Eneida, Joshi, Shivangi, Sandy, Peter, Mertz, Jennifer A, Sims, Robert J, Bergeron, Louise, Bryant, Barbara M, Bellon, Steve, Poy, Florence, Jayaram, Hariharan, Sankaranarayanan, Ravichandran, Yellapantula, Sreegouri, Bangalore Srinivasamurthy, Nandana, Birudukota, Swarnakumari, Albrecht, Brian K
Published in ACS medicinal chemistry letters (12.09.2013)
Published in ACS medicinal chemistry letters (12.09.2013)
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Journal Article
495 Trial of SNX281, a systemically delivered small molecule STING agonist, in solid tumors and lymphomas
Wang, Judy, Falchook, Gerald, Nabhan, Salah, Kulkarni, Meghana, Sandy, Peter, Dosunmu, Ololade, Gardner, Humphrey, Bendell, Johanna, Johnson, Melissa
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Drug Resistance Pattern of M. tuberculosis Complex in Oromia Region of Ethiopia
Bedru, Hussien, Fikru, Melaku, Niguse, Wardofa, Jemal, Aman, Getinet, Garoma, Gobena, Ameni, Hailu, Awraris, Peter, Sandy
Published in Infection and drug resistance (01.01.2021)
Published in Infection and drug resistance (01.01.2021)
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Journal Article
Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1
Gostissa, Monica, Hengstermann, Arnd, Fogal, Valentina, Sandy, Peter, Schwarz, Sylvia E., Scheffner, Martin, Del Sal, Giannino
Published in The EMBO journal (15.11.1999)
Published in The EMBO journal (15.11.1999)
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Journal Article
Discovery of Benzotriazolo[4,3‑d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains
Taylor, Alexander M, Vaswani, Rishi G, Gehling, Victor S, Hewitt, Michael C, Leblanc, Yves, Audia, James E, Bellon, Steve, Cummings, Richard T, Côté, Alexandre, Harmange, Jean-Christophe, Jayaram, Hari, Joshi, Shivangi, Lora, Jose M, Mertz, Jennifer A, Neiss, Adrianne, Pardo, Eneida, Nasveschuk, Christopher G, Poy, Florence, Sandy, Peter, Setser, Jeremy W, Sims, Robert J, Tang, Yong, Albrecht, Brian K
Published in ACS medicinal chemistry letters (11.02.2016)
Published in ACS medicinal chemistry letters (11.02.2016)
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