Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis
Schoors, Sandra, De Bock, Katrien, Cantelmo, Anna Rita, Georgiadou, Maria, Ghesquière, Bart, Cauwenberghs, Sandra, Kuchnio, Anna, Wong, Brian W., Quaegebeur, Annelies, Goveia, Jermaine, Bifari, Francesco, Wang, Xingwu, Blanco, Raquel, Tembuyser, Bieke, Cornelissen, Ivo, Bouché, Ann, Vinckier, Stefan, Diaz-Moralli, Santiago, Gerhardt, Holger, Telang, Sucheta, Cascante, Marta, Chesney, Jason, Dewerchin, Mieke, Carmeliet, Peter
Published in Cell metabolism (07.01.2014)
Published in Cell metabolism (07.01.2014)
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Journal Article
Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3‑(5-Fluoro‑1H‑indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate
Crosignani, Stefano, Bingham, Patrick, Bottemanne, Pauline, Cannelle, Hélène, Cauwenberghs, Sandra, Cordonnier, Marie, Dalvie, Deepak, Deroose, Frederik, Feng, Jun Li, Gomes, Bruno, Greasley, Samantha, Kaiser, Stephen E, Kraus, Manfred, Négrerie, Michel, Maegley, Karen, Miller, Nichol, Murray, Brion W, Schneider, Manfred, Soloweij, James, Stewart, Albert E, Tumang, Joseph, Torti, Vince R, Van Den Eynde, Benoit, Wythes, Martin
Published in Journal of medicinal chemistry (14.12.2017)
Published in Journal of medicinal chemistry (14.12.2017)
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Journal Article
Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy
Gomes, Bruno, Driessens, Gregory, Bartlett, Derek, Cai, Danying, Cauwenberghs, Sandra, Crosignani, Stefano, Dalvie, Deepak, Denies, Sofie, Dillon, Christopher P, Fantin, Valeria R, Guo, Jie, Letellier, Marie-Claire, Li, Wenlin, Maegley, Karen, Marillier, Reece, Miller, Nichol, Pirson, Romain, Rabolli, Virginie, Ray, Chad, Streiner, Nicole, Torti, Vince R, Tsaparikos, Konstantinos, Van den Eynde, Benoit J, Wythes, Martin, Yao, Li-Chin, Zheng, Xianxian, Tumang, Joseph, Kraus, Manfred
Published in Molecular cancer therapeutics (01.12.2018)
Published in Molecular cancer therapeutics (01.12.2018)
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Journal Article
Contribution of Platelet CX3CR1 to Platelet–Monocyte Complex Formation and Vascular Recruitment During Hyperlipidemia
Postea, Otilia, Vasina, Elena M, Cauwenberghs, Sandra, Projahn, Delia, Liehn, Elisa A, Lievens, Dirk, Theelen, Wendy, Kramp, Birgit K, Butoi, Elena D, Soehnlein, Oliver, Heemskerk, Johan W.M, Ludwig, Andreas, Weber, Christian, Koenen, Rory R
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2012)
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Journal Article
Shedding of procoagulant microparticles from unstimulated platelets by integrin-mediated destabilization of actin cytoskeleton
Cauwenberghs, Sandra, Feijge, Marion A.H., Harper, Alan G.S., Sage, Stewart O., Curvers, Joyce, Heemskerk, Johan W.M.
Published in FEBS letters (02.10.2006)
Published in FEBS letters (02.10.2006)
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Journal Article
Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation
Frommhold, David, Ludwig, Andreas, Bixel, M Gabriele, Zarbock, Alexander, Babushkina, Inna, Weissinger, Melitta, Cauwenberghs, Sandra, Ellies, Lesley G, Marth, Jamey D, Beck-Sickinger, Annette G, Sixt, Michael, Lange-Sperandio, Bärbel, Zernecke, Alma, Brandt, Ernst, Weber, Christian, Vestweber, Dietmar, Ley, Klaus, Sperandio, Markus
Published in The Journal of experimental medicine (09.06.2008)
Published in The Journal of experimental medicine (09.06.2008)
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Journal Article
Factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation
Daubie, Valéry, Cauwenberghs, Sandra, Senden, Nicole H.M., Pochet, Roland, Lindhout, Theo, Buurman, Wim A., Heemskerk, Johan W.M.
Published in Biochimica et biophysica acta (01.08.2006)
Published in Biochimica et biophysica acta (01.08.2006)
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Journal Article
Role of membrane cholesterol in platelet calcium signalling in response to VWF and collagen under stasis and flow
van Lier, Marjolijn, Verhoef, Sandra, Cauwenberghs, Sandra, Heemskerk, Johan W M, Akkerman, Jan-Willem N, Heijnen, Harry F G
Published in Thrombosis and haemostasis (01.06.2008)
Published in Thrombosis and haemostasis (01.06.2008)
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Journal Article
Role of PFKFB3-Driven Glycolysis in Vessel Sprouting
De Bock, Katrien, Georgiadou, Maria, Schoors, Sandra, Kuchnio, Anna, Wong, Brian W., Cantelmo, Anna Rita, Quaegebeur, Annelies, Ghesquière, Bart, Cauwenberghs, Sandra, Eelen, Guy, Phng, Li-Kun, Betz, Inge, Tembuyser, Bieke, Brepoels, Katleen, Welti, Jonathan, Geudens, Ilse, Segura, Inmaculada, Cruys, Bert, Bifari, Franscesco, Decimo, Ilaria, Blanco, Raquel, Wyns, Sabine, Vangindertael, Jeroen, Rocha, Susana, Collins, Russel T., Munck, Sebastian, Daelemans, Dirk, Imamura, Hiromi, Devlieger, Roland, Rider, Mark, Van Veldhoven, Paul P., Schuit, Frans, Bartrons, Ramon, Hofkens, Johan, Fraisl, Peter, Telang, Sucheta, DeBerardinis, Ralph J., Schoonjans, Luc, Vinckier, Stefan, Chesney, Jason, Gerhardt, Holger, Dewerchin, Mieke, Carmeliet, Peter
Published in Cell (01.08.2013)
Published in Cell (01.08.2013)
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Journal Article
Incomplete and transitory decrease of glycolysis: A new paradigm for anti-angiogenic therapy?
Schoors, Sandra, Cantelmo, Anna Rita, Georgiadou, Maria, Stapor, Peter, Wang, Xingwu, Quaegebeur, Annelies, Cauwenberghs, Sandra, Wong, Brian W, Bifari, Francesco, Decimo, Ilaria, Schoonjans, Luc, De Bock, Katrien, Dewerchin, Mieke, Carmeliet, Peter
Published in Cell cycle (Georgetown, Tex.) (01.01.2014)
Published in Cell cycle (Georgetown, Tex.) (01.01.2014)
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Journal Article
Contribution of platelet CX(3)CR1 to platelet-monocyte complex formation and vascular recruitment during hyperlipidemia
Postea, Otilia, Vasina, Elena M, Cauwenberghs, Sandra, Projahn, Delia, Liehn, Elisa A, Lievens, Dirk, Theelen, Wendy, Kramp, Birgit K, Butoi, Elena D, Soehnlein, Oliver, Heemskerk, Johan W M, Ludwig, Andreas, Weber, Christian, Koenen, Rory R
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2012)
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Journal Article
Loss or Inhibition of Stromal-Derived PlGF Prolongs Survival of Mice with Imatinib-Resistant Bcr-Abl1 + Leukemia
Schmidt, Thomas, Masouleh, Behzad Kharabi, Loges, Sonja, Cauwenberghs, Sandra, Fraisl, Peter, Maes, Christa, Jonckx, Bart, De Keersmaecker, Kim, Kleppe, Maria, Tjwa, Marc, Schenk, Thomas, Vinckier, Stefan, Fragoso, Rita, De Mol, Maria, Beel, Karolien, Dias, Sérgio, Verfaillie, Catherine, Clark, Richard E., Brümmendorf, Tim H., Vandenberghe, Peter, Rafii, Shahin, Holyoake, Tessa, Hochhaus, Andreas, Cools, Jan, Karin, Michael, Carmeliet, Geert, Dewerchin, Mieke, Carmeliet, Peter
Published in Cancer cell (14.06.2011)
Published in Cancer cell (14.06.2011)
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Abstract 4612: Development and validation of a screening platform for the identification of novel immuno-oncology targets
Scoumanne, Ariane, Rabolli, Virginie, Legrand, Lea, Martini, Murielle, Letellier, marie-claire, Crosignani, Stefano, Quéva, Christophe, Detheux, Michel, Cauwenberghs, Sandra, Swiercz, Jakub
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Loss or Inhibition of Stromal-Derived PlGF Prolongs Survival of Mice with Imatinib-Resistant Bcr-Abl1+ Leukemia
Schmidt, Thomas, Kharabi Masouleh, Behzad, Loges, Sonja, Cauwenberghs, Sandra, Fraisl, Peter, Maes, Christa, Jonckx, Bart, De Keersmaecker, Kim, Kleppe, Maria, Tjwa, Marc, Schenk, Thomas, Vinckier, Stefan, Fragoso, Rita, De Mol, Maria, Beel, Karolien, Dias, Sérgio, Verfaillie, Catherine, Clark, Richard E., Brümmendorf, Tim H., Vandenberghe, Peter, Rafii, Shahin, Holyoake, Tessa, Hochhaus, Andreas, Cools, Jan, Karin, Michael, Carmeliet, Geert, Dewerchin, Mieke, Carmeliet, Peter
Published in Cancer cell (13.01.2020)
Published in Cancer cell (13.01.2020)
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Journal Article
Vessel abnormalization: another hallmark of cancer?
De Bock, Katrien, Cauwenberghs, Sandra, Carmeliet, Peter
Published in Current opinion in genetics & development (2011)
Published in Current opinion in genetics & development (2011)
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Journal Article
Abstract 4863: PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune checkpoint inhibitors
Tumang, Joseph, Gomes, Bruno, Wythes, Martin, Crosignani, Stefano, Bingham, Patrick, Bottemanne, Pauline, Cannelle, Hélène, Cauwenberghs, Sandra, Chaplin, Jenny, Dalvie, Deepak, Denies, Sofie, De Maeseneire, Coraline, Folger, Peter, Frederix, Kim, Guo, Jie, Hardwick, James, Hook, Ken, Jessen, Katti, Kindt, Erick, Letellier, Marie-Claire, Liao, Kai-Hsin, Li, Wenlin, Maegley, Karen, Marillier, Reece, Miller, Nichol, Murray, Brion, Pirson, Romain, Preillon, Julie, Rabolli, Virginie, Ray, Chad, Scales, Stephanie, Srirangam, Jay, Solowiej, Jim, Streiner, Nicole, Torti, Vince, Tsaparikos, Konstantinos, Vicini, Paolo, Driessens, Gregory, Kraus, Manfred
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Aging- and activation-induced platelet microparticles suppress apoptosis in monocytic cells and differentially signal to proinflammatory mediator release
Vasina, Elena M, Cauwenberghs, Sandra, Staudt, Mareike, Feijge, Marion Ah, Weber, Christian, Koenen, Rory R, Heemskerk, Johan Wm
Published in American journal of blood research (01.01.2013)
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Published in American journal of blood research (01.01.2013)
Journal Article
Hemostatic and Signaling Functions of Transfused Platelets
Cauwenberghs, Sandra, van Pampus, Elisabeth, Curvers, Joyce, Akkerman, Jan-Willem N, Heemskerk, Johan W.M
Published in Transfusion medicine reviews (01.10.2007)
Published in Transfusion medicine reviews (01.10.2007)
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