HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML
Zhou, L, Ruvolo, V R, McQueen, T, Chen, W, Samudio, I J, Conneely, O, Konopleva, M, Andreeff, M
Published in Leukemia (01.06.2013)
Published in Leukemia (01.06.2013)
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The dual PI3 kinase mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML
Kojima, K, Shimanuki, M, Shikami, M, Samudio, I J, Ruvolo, V, Corn, P, Hanaoka, N, Konopleva, M, Andreeff, M, Nakakuma, H
Published in Leukemia (01.09.2008)
Published in Leukemia (01.09.2008)
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MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy
Kojima, Kensuke, Konopleva, Marina, Samudio, Ismael J., Shikami, Masato, Cabreira-Hansen, Maria, McQueen, Teresa, Ruvolo, Vivian, Tsao, Twee, Zeng, Zhihong, Vassilev, Lyubomir T., Andreeff, Michael
Published in Blood (01.11.2005)
Published in Blood (01.11.2005)
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The dual Pl3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML
KOJIMA, K, SHIMANUKI, M, SHIKAMI, M, SAMUDIO, I. J, RUVOLO, V, CORN, P, HANAOKA, N, KONOPLEVA, M, ANDREEFF, M, NAKAKUMA, H
Published in Leukemia (2008)
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Published in Leukemia (2008)
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A novel ring-substituted diindolylmethane, 1,1-bis[3'-(5-Methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia
CONTRACTOR, Rooha, SAMUDIO, Ismael J, ESTROV, Zeev, HARRIS, David, MCCUBREY, James A, SAFE, Stephen H, ANDREEFF, Michael, KONOPLEVA, Marina
Published in Cancer research (Chicago, Ill.) (01.04.2005)
Published in Cancer research (Chicago, Ill.) (01.04.2005)
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Simultaneous inhibition of PDK1/AKT and fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia
ZHIHONG ZENG, SAMUDIO, Ismael J, PENG HUANG, YILING LU, MILLS, Gordon B, ANDREEFF, Michael, KONOPLEVA, Marina, WEIGUO ZHANG, ESTROV, Zeev, PELICANO, Hélène, HARRIS, David, FROLOVA, Olga, HAIL, Numsen, WENJING CHEN, KORNBLAU, Steven M
Published in Cancer research (Chicago, Ill.) (01.04.2006)
Published in Cancer research (Chicago, Ill.) (01.04.2006)
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