eNAMPT neutralization reduces preclinical ARDS severity via rectified NFkB and Akt/mTORC2 signaling
Bermudez, Tadeo, Sammani, Saad, Song, Jin H., Hernon, Vivian Reyes, Kempf, Carrie L., Garcia, Alexander N., Burt, Jessica, Hufford, Matthew, Camp, Sara M., Cress, Anne E., Desai, Ankit A., Natarajan, Viswanathan, Jacobson, Jeffrey R., Dudek, Steven M., Cancio, Leopoldo C., Alvarez, Julie, Rafikov, Ruslan, Li, Yansong, Zhang, Donna D., Casanova, Nancy G., Bime, Christian, Garcia, Joe G. N.
Published in Scientific reports (13.01.2022)
Published in Scientific reports (13.01.2022)
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Journal Article
RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE–dependent repression
Liu, Pengfei, de la Vega, Montserrat Rojo, Sammani, Saad, Mascarenhas, Joseph B., Kerins, Michael, Dodson, Matthew, Sun, Xiaoguang, Wang, Ting, Ooi, Aikseng, Garcia, Joe G. N., Zhang, Donna D.
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2018)
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Journal Article
Imatinib attenuates inflammation and vascular leak in a clinically relevant two-hit model of acute lung injury
Rizzo, Alicia N, Sammani, Saad, Esquinca, Adilene E, Jacobson, Jeffrey R, Garcia, Joe G N, Letsiou, Eleftheria, Dudek, Steven M
Published in American journal of physiology. Lung cellular and molecular physiology (01.12.2015)
Published in American journal of physiology. Lung cellular and molecular physiology (01.12.2015)
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Journal Article
The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension
Chen, Jiwang, Tang, Haiyang, Sysol, Justin R, Moreno-Vinasco, Liliana, Shioura, Krystyna M, Chen, Tianji, Gorshkova, Irina, Wang, Lichun, Huang, Long Shuang, Usatyuk, Peter V, Sammani, Saad, Zhou, Guofei, Raj, J Usha, Garcia, Joe G N, Berdyshev, Evgeny, Yuan, Jason X-J, Natarajan, Viswanathan, Machado, Roberto F
Published in American journal of respiratory and critical care medicine (01.11.2014)
Published in American journal of respiratory and critical care medicine (01.11.2014)
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Journal Article
Pathologic mechanical stress and endotoxin exposure increases lung endothelial microparticle shedding
Letsiou, Eleftheria, Sammani, Saad, Zhang, Wei, Zhou, Tong, Quijada, Hector, Moreno-Vinasco, Liliana, Dudek, Steven M, Garcia, Joe G N
Published in American journal of respiratory cell and molecular biology (01.02.2015)
Published in American journal of respiratory cell and molecular biology (01.02.2015)
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Journal Article
Circadian disruption dysregulates lung gene expression associated with inflammatory lung injury
Casanova, Nancy G, De Armond, Richard L, Sammani, Saad, Sun, Xiaoguang, Sun, Belinda, Kempf, Carrie, Bime, Christian, Garcia, Joe G N, Parthasarathy, Sairam
Published in Frontiers in immunology (2024)
Published in Frontiers in immunology (2024)
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Journal Article
Differential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung
Sammani, Saad, Moreno-Vinasco, Liliana, Mirzapoiazova, Tamara, Singleton, Patrick A, Chiang, Eddie T, Evenoski, Carrie L, Wang, Ting, Mathew, Biji, Husain, Aliya, Moitra, Jaideep, Sun, Xiaoguang, Nunez, Luis, Jacobson, Jeffrey R, Dudek, Steven M, Natarajan, Viswanathan, Garcia, Joe G N
Published in American journal of respiratory cell and molecular biology (01.10.2010)
Published in American journal of respiratory cell and molecular biology (01.10.2010)
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Journal Article
An eNAMPT-neutralizing mAb reduces post-infarct myocardial fibrosis and left ventricular dysfunction
Liu, Zhonglin, Sammani, Saad, Barber, Christy J., Kempf, Carrie L., Li, Feng, Yang, Zhen, Bermudez, Rosendo T., Camp, Sara M., Herndon, Vivian Reyes, Furenlid, Lars R., Martin, Diego R., Garcia, Joe G.N.
Published in Biomedicine & pharmacotherapy (01.01.2024)
Published in Biomedicine & pharmacotherapy (01.01.2024)
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Journal Article
eNAMPT Neutralization Preserves Lung Fluid Balance and Reduces Acute Renal Injury in Porcine Sepsis/VILI-Induced Inflammatory Lung Injury
Sammani, Saad, Bermudez, Tadeo, Kempf, Carrie L, Song, Jin H, Fleming, Justin C, Reyes Hernon, Vivian, Hufford, Matthew, Tang, Lin, Cai, Hua, Camp, Sara M, Natarajan, Viswanathan, Jacobson, Jeffrey R, Dudek, Steven M, Martin, Diego R, Karmonik, Christof, Sun, Xiaoguang, Sun, Belinda, Casanova, Nancy G, Bime, Christian, Garcia, Joe G N
Published in Frontiers in physiology (22.06.2022)
Published in Frontiers in physiology (22.06.2022)
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Journal Article
Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb
Ahmed, Mohamed, Zaghloul, Nahla, Zimmerman, Prisca, Casanova, Nancy G., Sun, Xiaoguang, Song, Jin H., Hernon, Vivian Reyes, Sammani, Saad, Rischard, Franz, Rafikova, Olga, Rafikov, Ruslan, Makino, Ayako, Kempf, Carrie L., Camp, Sara M., Wang, Jian, Desai, Ankit A., Lussier, Yves, Yuan, Jason X.-J., Garcia, Joe G.N.
Published in Pulmonary circulation (01.10.2021)
Published in Pulmonary circulation (01.10.2021)
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Journal Article
Protective Effects of Sphingosine 1-Phosphate in Murine Endotoxin-induced Inflammatory Lung Injury
Peng, Xinqi, Hassoun, Paul M, Sammani, Saad, McVerry, Bryan J, Burne, Melissa J, Rabb, Hamid, Pearse, David, Tuder, Rubin M, Garcia, Joe G. N
Published in American journal of respiratory and critical care medicine (01.06.2004)
Published in American journal of respiratory and critical care medicine (01.06.2004)
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Journal Article
The eNAMPT/TLR4 inflammatory cascade drives the severity of intra-amniotic inflammation in pregnancy and predicts infant outcomes
Ahmed, Mohamed, Casanova, Nancy G, Zaghloul, Nahla, Gupta, Akash, Rodriguez, Marisela, Robbins, Ian R, Kempf, Carrie L, Sun, Xiaoguang, Song, Jin H, Hernon, Vivian Reyes, Sammani, Saad, Camp, Sara M, Moreira, Alvaro, Hsu, Chaur-Dong, Garcia, Joe G N
Published in Frontiers in physiology (20.06.2023)
Published in Frontiers in physiology (20.06.2023)
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Journal Article
Nicotinamide phosphoribosyltransferase inhibitor is a novel therapeutic candidate in murine models of inflammatory lung injury
Moreno-Vinasco, Liliana, Quijada, Hector, Sammani, Saad, Siegler, Jessica, Letsiou, Eleftheria, Deaton, Ryan, Saadat, Laleh, Zaidi, Rafe S, Messana, Joe, Gann, Peter H, Machado, Roberto F, Ma, Wenli, Camp, Sara M, Wang, Ting, Garcia, Joe G N
Published in American journal of respiratory cell and molecular biology (01.08.2014)
Published in American journal of respiratory cell and molecular biology (01.08.2014)
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Journal Article
High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness
Singleton, Patrick A, Mirzapoiazova, Tamara, Guo, Yurong, Sammani, Saad, Mambetsariev, Nurbek, Lennon, Frances E, Moreno-Vinasco, Liliana, Garcia, Joe G N
Published in American journal of physiology. Lung cellular and molecular physiology (01.11.2010)
Published in American journal of physiology. Lung cellular and molecular physiology (01.11.2010)
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Journal Article
Pleiotropic effects of interleukin-6 in a “two-hit” murine model of acute respiratory distress syndrome
Goldman, Julia L., Sammani, Saad, Kempf, Carrie, Saadat, Laleh, Letsiou, Eleftheria, Wang, Ting, Moreno-Vinasco, Liliana, Rizzo, Alicia N., Fortman, Jeffrey D., Garcia, Joe G. N.
Published in Pulmonary circulation (01.06.2014)
Published in Pulmonary circulation (01.06.2014)
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Journal Article
Hyaluronic Acid Binding Protein 2 Is a Novel Regulator of Vascular Integrity
Mambetsariev, Nurbek, Mirzapoiazova, Tamara, Mambetsariev, Bolot, Sammani, Saad, Lennon, Frances E, Garcia, Joe G.N, Singleton, Patrick A
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2010)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2010)
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Journal Article
Differential regulation of sphingosine kinases 1 and 2 in lung injury
Wadgaonkar, Raj, Patel, Vipul, Grinkina, Natalia, Romano, Carol, Liu, Jing, Zhao, Yutong, Sammani, Saad, Garcia, Joe G. N, Natarajan, Viswanathan
Published in American journal of physiology. Lung cellular and molecular physiology (01.04.2009)
Published in American journal of physiology. Lung cellular and molecular physiology (01.04.2009)
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Journal Article
Hydrogen sulfide attenuates particulate matter-induced human lung endothelial barrier disruption via combined reactive oxygen species scavenging and Akt activation
Wang, Ting, Wang, Lichun, Zaidi, Syed R, Sammani, Saad, Siegler, Jessica, Moreno-Vinasco, Liliana, Mathew, Biji, Natarajan, Viswanathan, Garcia, Joe G N
Published in American journal of respiratory cell and molecular biology (01.10.2012)
Published in American journal of respiratory cell and molecular biology (01.10.2012)
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Journal Article
Targeting SELPLG/P‐selectin glycoprotein ligand 1 in preclinical ARDS: Genetic and epigenetic regulation of the SELPLG promoter
Sun, Xiaoguang, Sammani, Saad, Hufford, Matthew, Sun, Belinda L., Kempf, Carrie L., Camp, Sara M., Garcia, Joe G. N., Bime, Christian
Published in Pulmonary circulation (01.01.2023)
Published in Pulmonary circulation (01.01.2023)
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Journal Article