Calcium Channels and Oxidative Stress Mediate a Synergistic Disruption of Tight Junctions by Ethanol and Acetaldehyde in Caco-2 Cell Monolayers
Samak, Geetha, Gangwar, Ruchika, Meena, Avtar S., Rao, Roshan G., Shukla, Pradeep K., Manda, Bhargavi, Narayanan, Damodaran, Jaggar, Jonathan H., Rao, RadhaKrishna
Published in Scientific reports (13.12.2016)
Published in Scientific reports (13.12.2016)
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Journal Article
ALDH2 Deficiency Promotes Ethanol-Induced Gut Barrier Dysfunction and Fatty Liver in Mice
Chaudhry, Kamaljit K., Samak, Geetha, Shukla, Pradeep K., Mir, Hina, Gangwar, Ruchika, Manda, Bhargavi, Isse, Toyohi, Kawamoto, Toshihiro, Salaspuro, Mikko, Kaihovaara, Pertti, Dietrich, Paula, Dragatsis, Ioannis, Nagy, Laura E., Rao, Radha Krishna
Published in Alcoholism, clinical and experimental research (01.08.2015)
Published in Alcoholism, clinical and experimental research (01.08.2015)
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Journal Article
Protein kinase Cζ phosphorylates occludin and promotes assembly of epithelial tight junctions
Jain, Suneet, Suzuki, Takuya, Seth, Ankur, Samak, Geetha, Rao, Radhakrishna
Published in Biochemical journal (15.07.2011)
Published in Biochemical journal (15.07.2011)
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Journal Article
Calcium/Ask1/MKK7/JNK2/c-Src signalling cascade mediates disruption of intestinal epithelial tight junctions by dextran sulfate sodium
Samak, Geetha, Chaudhry, Kamaljit K, Gangwar, Ruchika, Narayanan, Damodaran, Jaggar, Jonathan H, Rao, RadhaKrishna
Published in Biochemical journal (01.02.2015)
Published in Biochemical journal (01.02.2015)
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Journal Article
Cyclic stretch disrupts apical junctional complexes in Caco-2 cell monolayers by a JNK-2-, c-Src-, and MLCK-dependent mechanism
Samak, Geetha, Gangwar, Ruchika, Crosby, Lynn M, Desai, Leena P, Wilhelm, Kristina, Waters, Christopher M, Rao, RadhaKrishna
Published in American journal of physiology: Gastrointestinal and liver physiology (01.06.2014)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.06.2014)
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Journal Article
CaV1.3 channels and intracellular calcium mediate osmotic stress-induced N-terminal c-Jun kinase activation and disruption of tight junctions in Caco-2 cell monolayers
Samak, Geetha, Narayanan, Damodaran, Jaggar, Jonathan H., Rao, RadhaKrishna
Published in The Journal of biological chemistry (01.02.2012)
Published in The Journal of biological chemistry (01.02.2012)
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Journal Article
Superoxide and hydroxyl radical scavenging actions of botanical extracts of Wagatea spicata
Samak, Geetha, Shenoy, Revathi P., Manjunatha, S.M., Vinayak, K.S.
Published in Food chemistry (15.07.2009)
Published in Food chemistry (15.07.2009)
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Journal Article
Lactobacillus Casei Prevents Osmotic Stress-Induced Disruption of Tight Junctions (TJ) and Adherens Junctions (AJ) in CACO-2 Cell Monolayers by a PKC-Dependent Mechanism, but Independent of EGF Receptor Tyrosine Kinase Activity
Rao, Rupa, Samak, Geetha, Rao, Radhakrishna (RK)
Published in Gastroenterology (New York, N.Y. 1943) (2011)
Published in Gastroenterology (New York, N.Y. 1943) (2011)
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Journal Article
988 Lipopolysaccharide Primes Bile Duct Epithelial Monolayers for Tumor Necrosis Factor-a-Induced Tight Junction Disruption by an NfkB-Dependent Mechanism
Tombazzi, Claudio R, Samak, Geetha, Rao, Radhakrishna (RK)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
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Journal Article
CaV1.3 Channels and Intracellular Calcium Mediate Osmotic Stress-induced N-terminal c-Jun Kinase Activation and Disruption of Tight Junctions in Caco-2 Cell Monolayers
Samak, Geetha, Narayanan, Damodaran, Jaggar, Jonathan H., Rao, RadhaKrishna
Published in The Journal of biological chemistry (26.08.2011)
Published in The Journal of biological chemistry (26.08.2011)
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Journal Article
CA V 1.3, the Apical Membrane Calcium Channel, Mediates Osmotic Stress-Induced Calcium Influx, JNK2 Activation and Tight Junction (TJ) Disruption in CACO-2 Cell Monolayers
Samak, Geetha, Narayanan, Damodaran, Jaggar, Jonathan H., Rao, Radhakrishna (RK)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2011)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2011)
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Journal Article
CAV 1.3, the Apical Membrane Calcium Channel, Mediates Osmotic Stress-Induced Calcium Influx, JNK2 Activation and Tight Junction (TJ) Disruption in CACO-2 Cell Monolayers
Samak, Geetha, Narayanan, Damodaran, Jaggar, Jonathan H, Rao, Radhakrishna (RK)
Published in Gastroenterology (New York, N.Y. 1943) (2011)
Published in Gastroenterology (New York, N.Y. 1943) (2011)
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Journal Article