Targeting cancer metabolism in the era of precision oncology
Stine, Zachary E., Schug, Zachary T., Salvino, Joseph M., Dang, Chi V.
Published in Nature reviews. Drug discovery (01.02.2022)
Published in Nature reviews. Drug discovery (01.02.2022)
Get full text
Journal Article
Elevated pre-mRNA 3′ end processing activity in cancer cells renders vulnerability to inhibition of cleavage and polyadenylation
Cui, Yange, Wang, Luyang, Ding, Qingbao, Shin, Jihae, Cassel, Joel, Liu, Qin, Salvino, Joseph M., Tian, Bin
Published in Nature communications (01.08.2023)
Published in Nature communications (01.08.2023)
Get full text
Journal Article
The Natural Stilbenoid (–)-Hopeaphenol Inhibits Cellular Entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7, and B.1.351 Variants
Tietjen, Ian, Cassel, Joel, Register, Emery T, Zhou, Xiang Yang, Messick, Troy E, Keeney, Frederick, Lu, Lily D, Beattie, Karren D, Rali, Topul, Tebas, Pablo, Ertl, Hildegund C. J, Salvino, Joseph M, Davis, Rohan A, Montaner, Luis J
Published in Antimicrobial agents and chemotherapy (17.11.2021)
Published in Antimicrobial agents and chemotherapy (17.11.2021)
Get full text
Journal Article
Recent Advances in Metal-Catalyzed Approaches for the Synthesis of Quinazoline Derivatives
Nandwana, Nitesh K, Patel, Om P S, Mehra, Manish K, Kumar, Anil, Salvino, Joseph M
Published in Molecules (Basel, Switzerland) (01.05.2024)
Published in Molecules (Basel, Switzerland) (01.05.2024)
Get full text
Journal Article
Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells
Shen, Fei, Zhang, Yun, Jernigan, Danielle L, Feng, Xin, Yan, Jie, Garcia, Fernando U, Meucci, Olimpia, Salvino, Joseph M, Fatatis, Alessandro
Published in Molecular cancer research (01.06.2016)
Published in Molecular cancer research (01.06.2016)
Get full text
Journal Article
Increased glucose availability sensitizes pancreatic cancer to chemotherapy
Vaziri-Gohar, Ali, Hue, Jonathan J., Abbas, Ata, Graor, Hallie J., Hajihassani, Omid, Zarei, Mehrdad, Titomihelakis, George, Feczko, John, Rathore, Moeez, Chelstowska, Sylwia, Loftus, Alexander W., Wang, Rui, Zarei, Mahsa, Goudarzi, Maryam, Zhang, Renliang, Willard, Belinda, Zhang, Li, Kresak, Adam, Willis, Joseph E., Wang, Gi-Ming, Tatsuoka, Curtis, Salvino, Joseph M., Bederman, Ilya, Brunengraber, Henri, Lyssiotis, Costas A., Brody, Jonathan R., Winter, Jordan M.
Published in Nature communications (28.06.2023)
Published in Nature communications (28.06.2023)
Get full text
Journal Article
A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors
Barnoud, Thibaut, Leung, Jessica C, Leu, Julia I-Ju, Basu, Subhasree, Poli, Adi Narayana Reddy, Parris, Joshua L D, Indeglia, Alexandra, Martynyuk, Tetyana, Good, Madeline, Gnanapradeepan, Keerthana, Sanseviero, Emilio, Moeller, Rebecca, Tang, Hsin-Yao, Cassel, Joel, Kossenkov, Andrew V, Liu, Qin, Speicher, David W, Gabrilovich, Dmitry I, Salvino, Joseph M, George, Donna L, Murphy, Maureen E
Published in Cancer research (Chicago, Ill.) (01.12.2020)
Published in Cancer research (Chicago, Ill.) (01.12.2020)
Get full text
Journal Article
Identification of Novel Allosteric Modulators of Glutamate Transporter EAAT2
Kortagere, Sandhya, Mortensen, Ole V, Xia, Jingsheng, Lester, William, Fang, Yuhong, Srikanth, Yellamelli, Salvino, Joseph M, Fontana, Andréia C. K
Published in ACS chemical neuroscience (21.03.2018)
Published in ACS chemical neuroscience (21.03.2018)
Get full text
Journal Article
Small molecule perturbation of the CAND1-Cullin1-ubiquitin cycle stabilizes p53 and triggers Epstein-Barr virus reactivation
Tikhmyanova, Nadezhda, Tutton, Steve, Martin, Kayla A, Lu, Fang, Kossenkov, Andrew V, Paparoidamis, Nicholas, Kenney, Shannon, Salvino, Joseph M, Lieberman, Paul M
Published in PLoS pathogens (17.07.2017)
Published in PLoS pathogens (17.07.2017)
Get full text
Journal Article
Elucidation of the Structure and Synthesis of Neuroprotective Low Molecular Mass Components of the Parawixia bistriata Spider Venom
Forster, Yvonne M, Green, Jennifer Leigh, Khatiwada, Apeksha, Liberato, José Luiz, Narayana Reddy, Poli Adi, Salvino, Joseph M, Bienz, Stefan, Bigler, Laurent, Dos Santos, Wagner Ferreira, Karklin Fontana, Andréia Cristina
Published in ACS chemical neuroscience (03.06.2020)
Published in ACS chemical neuroscience (03.06.2020)
Get full text
Journal Article
Knowledge-based chemoinformatic approaches to drug discovery
Ghose, Arup K., Herbertz, Torsten, Salvino, Joseph M., Mallamo, John P.
Published in Drug discovery today (01.12.2006)
Published in Drug discovery today (01.12.2006)
Get full text
Journal Article
Targeted MDM2 Degradation Reveals a New Vulnerability for p53-Inactivated Triple-Negative Breast Cancer
Adams, Clare M, Mitra, Ramkrishna, Xiao, Youcai, Michener, Peter, Palazzo, Juan, Chao, Allen, Gour, Jitendra, Cassel, Joel, Salvino, Joseph M, Eischen, Christine M
Published in Cancer discovery (04.05.2023)
Published in Cancer discovery (04.05.2023)
Get full text
Journal Article
Rapid Optimization of the Metabolic Stability of a Human Immunodeficiency Virus Type‑1 Capsid Inhibitor Using a Multistep Computational Workflow
Meuser, Megan E, Reddy, Poli Adi Narayana, Dick, Alexej, Maurancy, Jean Marc, Salvino, Joseph M, Cocklin, Simon
Published in Journal of medicinal chemistry (08.04.2021)
Published in Journal of medicinal chemistry (08.04.2021)
Get full text
Journal Article
Selective inhibition of Ph-positive ALL cell growth through kinase-dependent and -independent effects by CDK6-specific PROTACs
De Dominici, Marco, Porazzi, Patrizia, Xiao, Youcai, Chao, Allen, Tang, Hsin-Yao, Kumar, Gaurav, Fortina, Paolo, Spinelli, Orietta, Rambaldi, Alessandro, Peterson, Luke F., Petruk, Svetlana, Barletta, Camilla, Mazo, Alexander, Cingolani, Gino, Salvino, Joseph M., Calabretta, Bruno
Published in Blood (30.04.2020)
Published in Blood (30.04.2020)
Get full text
Journal Article
IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance
Singh, Kumar Sachin, Sharma, Rishabh, Reddy, Poli Adi Narayana, Vonteddu, Prashanthi, Good, Madeline, Sundarrajan, Anjana, Choi, Hyeree, Muthumani, Kar, Kossenkov, Andrew, Goldman, Aaron R, Tang, Hsin-Yao, Totrov, Maxim, Cassel, Joel, Murphy, Maureen E, Somasundaram, Rajasekharan, Herlyn, Meenhard, Salvino, Joseph M, Dotiwala, Farokh
Published in Nature (London) (28.01.2021)
Published in Nature (London) (28.01.2021)
Get full text
Journal Article
Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth
Miller, Katelyn D, Pniewski, Katherine, Perry, Caroline E, Papp, Sara B, Shaffer, Joshua D, Velasco-Silva, Jesse N, Casciano, Jessica C, Aramburu, Tomas M, Srikanth, Yellamelli V V, Cassel, Joel, Skordalakes, Emmanuel, Kossenkov, Andrew V, Salvino, Joseph M, Schug, Zachary T
Published in Cancer research (Chicago, Ill.) (01.03.2021)
Published in Cancer research (Chicago, Ill.) (01.03.2021)
Get full text
Journal Article