US FDA 505(b)(2) NDA clinical, CMC and regulatory strategy concepts to expedite drug development
Salminen, William F., Aloba, Olu, Drew, Angela, Marcinowicz, Agnieszka, Huang, Madelyn
Published in Drug discovery today (01.07.2023)
Published in Drug discovery today (01.07.2023)
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Streamlining nonclinical drug development using the FDA 505(b)(2) new drug application regulatory pathway
Salminen, William F., Wiles, Marc E., Stevens, Ruth E.
Published in Drug discovery today (01.01.2019)
Published in Drug discovery today (01.01.2019)
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Inhibition of cytochrome P450s enhances (+)-usnic acid cytotoxicity in primary cultured rat hepatocytes
Shi, Qiang, Greenhaw, James, Salminen, William F.
Published in Journal of applied toxicology (01.08.2014)
Published in Journal of applied toxicology (01.08.2014)
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Journal Article
Effects of 31 FDA approved small-molecule kinase inhibitors on isolated rat liver mitochondria
Zhang, Jun, Salminen, Alec, Yang, Xi, Luo, Yong, Wu, Qiangen, White, Matthew, Greenhaw, James, Ren, Lijun, Bryant, Matthew, Salminen, William, Papoian, Thomas, Mattes, William, Shi, Qiang
Published in Archives of toxicology (01.08.2017)
Published in Archives of toxicology (01.08.2017)
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Journal Article
Potential of extracellular microRNAs as biomarkers of acetaminophen toxicity in children
Yang, Xi, Salminen, William F., Shi, Qiang, Greenhaw, James, Gill, Pritmohinder S., Bhattacharyya, Sudeepa, Beger, Richard D., Mendrick, Donna L., Mattes, William B., James, Laura P.
Published in Toxicology and applied pharmacology (15.04.2015)
Published in Toxicology and applied pharmacology (15.04.2015)
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Identification of Urinary microRNA Profiles in Rats That May Diagnose Hepatotoxicity
Yang, Xi, Greenhaw, James, Shi, Qiang, Su, Zhenqiang, Qian, Feng, Davis, Kelly, Mendrick, Donna L., Salminen, William F.
Published in Toxicological sciences (01.02.2012)
Published in Toxicological sciences (01.02.2012)
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Metabolomics evaluation of the effects of green tea extract on acetaminophen-induced hepatotoxicity in mice
Lu, Yihong, Sun, Jinchun, Petrova, Katya, Yang, Xi, Greenhaw, James, Salminen, William F., Beger, Richard D., Schnackenberg, Laura K.
Published in Food and chemical toxicology (01.12.2013)
Published in Food and chemical toxicology (01.12.2013)
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Green tea extract can potentiate acetaminophen-induced hepatotoxicity in mice
Salminen, William F., Yang, Xi, Shi, Qiang, Greenhaw, James, Davis, Kelly, Ali, Akhtar A.
Published in Food and chemical toxicology (01.05.2012)
Published in Food and chemical toxicology (01.05.2012)
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Journal Article
Green tea epigallocatechin gallate binds to and inhibits respiratory complexes in swelling but not normal rat hepatic mitochondria
Weng, Zuquan, Zhou, Peng, Salminen, William F., Yang, Xi, Harrill, Alison H., Cao, Zhijun, Mattes, William B., Mendrick, Donna L., Shi, Qiang
Published in Biochemical and biophysical research communications (17.01.2014)
Published in Biochemical and biophysical research communications (17.01.2014)
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A randomized controlled laboratory study on the long-term effects of methylphenidate on cardiovascular function and structure in rhesus monkeys
Wilkinson, James D, Callicott, Ralph, Salminen, William F, Sandhu, Satinder K, Greenhaw, James, Paredes, Angel, Davis, Kelly, Jones, Yvonne, Paule, Merle G, Slikker, Jr, William, Rusconi, Paolo G, Czachor, Jason, Bodien, Amy, Westphal, Joslyn A, Dauphin, Danielle D, Lipshultz, Steven E
Published in Pediatric research (01.02.2019)
Published in Pediatric research (01.02.2019)
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Mechanisms for epigallocatechin gallate induced inhibition of drug metabolizing enzymes in rat liver microsomes
Weng, Zuquan, Greenhaw, James, Salminen, William F., Shi, Qiang
Published in Toxicology letters (15.11.2012)
Published in Toxicology letters (15.11.2012)
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Journal Article
Proteomic analysis of acetaminophen‐induced hepatotoxicity and identification of heme oxygenase 1 as a potential plasma biomarker of liver injury
Gao, Yuan, Cao, Zhijun, Yang, Xi, Abdelmegeed, Mohamed A., Sun, Jinchun, Chen, Si, Beger, Richard D., Davis, Kelly, Salminen, William F., Song, Byoung‐Joon, Mendrick, Donna L., Yu, Li‐Rong
Published in Proteomics. Clinical applications (01.01.2017)
Published in Proteomics. Clinical applications (01.01.2017)
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Journal Article
Mouse liver protein sulfhydryl depletion after acetaminophen exposure
Yang, Xi, Greenhaw, James, Shi, Qiang, Roberts, Dean W, Hinson, Jack A, Muskhelishvili, Levan, Davis, Kelly, Salminen, William F
Published in The Journal of pharmacology and experimental therapeutics (01.01.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2013)
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A Unique Formulation of Cardioprotective Bio-Actives: An Overview of Their Safety Profile
Salminen, William, Agbaje-Williams, Mayowa, Ajayi, Funmilayo O
Published in Medicines (Basel, Switzerland) (22.10.2019)
Published in Medicines (Basel, Switzerland) (22.10.2019)
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Journal Article
Changes in mouse liver protein glutathionylation after acetaminophen exposure
Yang, Xi, Greenhaw, James, Ali, Akhtar, Shi, Qiang, Roberts, Dean W, Hinson, Jack A, Muskhelishvili, Levan, Beger, Richard, Pence, Lisa M, Ando, Yosuke, Sun, Jinchun, Davis, Kelly, Salminen, William F
Published in The Journal of pharmacology and experimental therapeutics (01.02.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2012)
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Comprehensive analysis of alterations in lipid and bile acid metabolism by carbon tetrachloride using integrated transcriptomics and metabolomics
Sun, Jinchun, Schmitt, Thomas, Schnackenberg, Laura K., Pence, Lisa, Ando, Yosuke, Greenhaw, James, Yang, Xi, Slavov, Svetoslav, Davis, Kelly, Salminen, William F., Mendrick, Donna L., Beger, Richard D.
Published in Metabolomics (01.12.2014)
Published in Metabolomics (01.12.2014)
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Identification of a metabolic biomarker panel in rats for prediction of acute and idiosyncratic hepatotoxicity
Sun, Jinchun, Slavov, Svetoslav, Schnackenberg, Laura K., Ando, Yosuke, Greenhaw, James, Yang, Xi, Salminen, William, Mendrick, Donna L., Beger, Richard
Published in Computational and structural biotechnology journal (01.07.2014)
Published in Computational and structural biotechnology journal (01.07.2014)
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