Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279
Leit, Silvana, Greenwood, Jeremy, Carriero, Samantha, Mondal, Sayan, Abel, Robert, Ashwell, Mark, Blanchette, Heather, Boyles, Nicholas A., Cartwright, Mark, Collis, Alan, Feng, Shulu, Ghanakota, Phani, Harriman, Geraldine C., Hosagrahara, Vinayak, Kaila, Neelu, Kapeller, Rosanna, Rafi, Salma B., Romero, Donna L., Tarantino, Paul M., Timaniya, Jignesh, Toms, Angela V., Wester, Ronald T., Westlin, William, Srivastava, Bhaskar, Miao, Wenyan, Tummino, Peter, McElwee, Joshua J., Edmondson, Scott D., Masse, Craig E.
Published in Journal of medicinal chemistry (10.08.2023)
Published in Journal of medicinal chemistry (10.08.2023)
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Journal Article
Reliable and Accurate Solution to the Induced Fit Docking Problem for Protein–Ligand Binding
Miller, Edward B, Murphy, Robert B, Sindhikara, Daniel, Borrelli, Kenneth W, Grisewood, Matthew J, Ranalli, Fabio, Dixon, Steven L, Jerome, Steven, Boyles, Nicholas A, Day, Tyler, Ghanakota, Phani, Mondal, Sayan, Rafi, Salma B, Troast, Dawn M, Abel, Robert, Friesner, Richard A
Published in Journal of chemical theory and computation (13.04.2021)
Published in Journal of chemical theory and computation (13.04.2021)
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Journal Article
Predicting and Improving the Membrane Permeability of Peptidic Small Molecules
Rafi, Salma B, Hearn, Brian R, Vedantham, Punitha, Jacobson, Matthew P, Renslo, Adam R
Published in Journal of medicinal chemistry (12.04.2012)
Published in Journal of medicinal chemistry (12.04.2012)
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Journal Article
Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni
Ingram, Jessica R, Rafi, Salma B, Eroy-Reveles, A Alegra, Ray, Manisha, Lambeth, Laura, Hsieh, Ivy, Ruelas, Debbie, Lim, K C, Sakanari, Judy, Craik, Charles S, Jacobson, Matthew P, McKerrow, James H
Published in PLoS neglected tropical diseases (01.04.2012)
Published in PLoS neglected tropical diseases (01.04.2012)
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Journal Article
Structure of Acyl Carrier Protein Bound to FabI, the FASII Enoyl Reductase from Escherichia coli
Rafi, Salma, Novichenok, Polina, Kolappan, Subramaniapillai, Zhang, Xujie, Stratton, Christopher F., Rawat, Richa, Kisker, Caroline, Simmerling, Carlos, Tonge, Peter J.
Published in The Journal of biological chemistry (22.12.2006)
Published in The Journal of biological chemistry (22.12.2006)
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Journal Article
Insight through Molecular Mechanics Poisson−Boltzmann Surface Area Calculations into the Binding Affinity of Triclosan and Three Analogues for FabI, the E. coli Enoyl Reductase
Rafi, Salma B, Cui, Guanglei, Song, Kun, Cheng, Xiaolin, Tonge, Peter J, Simmerling, Carlos
Published in Journal of medicinal chemistry (27.07.2006)
Published in Journal of medicinal chemistry (27.07.2006)
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Journal Article
An allosteric mechanism for potent inhibition of human ATP-citrate lyase
Wei, Jia, Leit, Silvana, Kuai, Jun, Therrien, Eric, Rafi, Salma, Harwood, H. James, DeLaBarre, Byron, Tong, Liang
Published in Nature (London) (01.04.2019)
Published in Nature (London) (01.04.2019)
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Journal Article
Cryo-EM structure of human ATP-citrate lyase in complex with a potent inhibitor
Wei, Jia, Leit, Silvana, Kuai, Jun, Therrien, Eric, Rafi, Salma, Harwood Jr, H. James, DeLaBarre, Byron, Tong, Liang
Published in Acta crystallographica. Section A, Foundations and advances (20.07.2019)
Published in Acta crystallographica. Section A, Foundations and advances (20.07.2019)
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Journal Article
INHIBITING HUMAN INTEGRIN (ALPHA-4) (BETA-7)
BLAISE S LIPPA, CUI DAN, BRYCE A HARRISON, KIM BYUNGCHAN, EUGENE HICKEY, ROBERT ZAHLER, TYLER DAY, EVELYNE HOUANG, ALEKSEY I GERASYUTO, MATTHEW G BURSAVICH, KYLE D KONZE, BRUCE N ROGERS, JAMES E DOWLING, SALMA RAFI, KRISTOPHER N HAHN, LIN FU-YANG, DAWN M TROAST, ZHONG CHENG
Year of Publication 16.04.2024
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Year of Publication 16.04.2024
Patent
INHIBITING HUMAN INTEGRIN α4β7
BLAISE S LIPPA, CUI DAN, BRYCE A HARRISON, KIM BYUNGCHAN, EUGENE HICKEY, ROBERT ZAHLER, TYLER DAY, EVELYNE HOUANG, ALEKSEY I GERASYUTO, MATTHEW G BURSAVICH, KYLE D KONZE, BRUCE N ROGERS, JAMES E DOWLING, SALMA RAFI, KRISTOPHER N HAHN, LIN FU-YANG, DAWN M TROAST, ZHONG CHENG
Year of Publication 16.04.2024
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Year of Publication 16.04.2024
Patent
Microfaunal Assemblage of the Sui Main Limestone from Sui Gas Field, Pakistan
Rafi, Salma, Khursheed, S.H., Mohsin, Syed Iqbal
Published in Journal of basic and applied sciences (25.01.2012)
Published in Journal of basic and applied sciences (25.01.2012)
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Journal Article
CBL-B MODULATORS AND USES THEREOF
LEIT DE MORADEI, Silvana Marcel, RAFI, Salma B, WEST, Angela V, CAMPOS, Sebastien, GREENWOOD, Jeremy Robert, FEYFANT, Eric René Pierre, GRAVES, Alan
Year of Publication 25.07.2024
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Year of Publication 25.07.2024
Patent
CBL-B MODULATORS AND USES THEREOF
LEIT DE MORADEI, Silvana Marcel, RAFI, Salma B, WEST, Angela V, CAMPOS, Sebastien, GREENWOOD, Jeremy Robert, FEYFANT, Eric René Pierre, GRAVES, Alan
Year of Publication 27.06.2024
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Year of Publication 27.06.2024
Patent
CBL-B MODULATORS AND USES THEREOF
LEIT DE MORADEI, Silvana Marcel, RAFI, Salma, BAKER, Thomas, WEST, Angela V, ZHANG, Yan, ARREGUI, Jokin Carrillo, CASTAGNA, Diana, GREENWOOD, Jeremy Robert, MCROBB, Fiona
Year of Publication 01.05.2024
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Year of Publication 01.05.2024
Patent
CBL-B MODULATORS AND USES THEREOF
LEIT DE MORADEI, Silvana Marcel, RAFI, Salma B, WEST, Angela V, CAMPOS, Sebastien, FEYFANT, Eric René Pierre, GRAVES, Alan
Year of Publication 18.04.2024
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Year of Publication 18.04.2024
Patent
CBL-B MODULATORS AND USES THEREOF
LEIT DE MORADEI, Silvana Marcel, RAFI, Salma, BAKER, Thomas, WEST, Angela V, ZHANG, Yan, ARREGUI, Jokin Carrillo, CASTAGNA, Diana, GREENWOOD, Jeremy Robert, MCROBB, Fiona
Year of Publication 14.02.2024
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Year of Publication 14.02.2024
Patent
Cbl-b modulators and uses thereof
WEST Angela V, ARREGUI Jokin Carrillo, ZHANG Yan, MCROBB Fiona, LEIT DE MORADEI Silvana Marcel, BAKER Thomas, CASTAGNA Diana, RAFI Salma, GREENWOOD Jeremy Robert
Year of Publication 01.12.2023
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Year of Publication 01.12.2023
Patent
CBL-B MODULATORS AND USES THEREOF
LEIT DE MORADEI, Silvana Marcel, RAFI, Salma, BAKER, Thomas, WEST, Angela V, ZHANG, Yan, ARREGUI, Jokin Carrillo, CASTAGNA, Diana, GREENWOOD, Jeremy Robert, MCROBB, Fiona
Year of Publication 02.11.2023
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Year of Publication 02.11.2023
Patent
CBL-B MODULATORS AND USES THEREOF
LEIT DE MORADEI, Silvana Marcel, RAFI, Salma, BAKER, Thomas, WEST, Angela V, ZHANG, Yan, ARREGUI, Jokin Carrillo, CASTAGNA, Diana, GREENWOOD, Jeremy Robert, MCROBB, Fiona
Year of Publication 01.06.2023
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Year of Publication 01.06.2023
Patent