sTREM-1 is a specific biomarker of TREM-1 pathway activation
Jolly, Lucie, Carrasco, Kévin, Salcedo-Magguilli, Margarita, Garaud, Jean-Jacques, Lambden, Simon, van der Poll, Tom, Mebazaa, Alexandre, Laterre, Pierre-François, Gibot, Sebastien, Boufenzer, Amir, Derive, Marc
Published in Cellular & molecular immunology (01.08.2021)
Published in Cellular & molecular immunology (01.08.2021)
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Journal Article
A first‐in‐man safety and pharmacokinetics study of nangibotide, a new modulator of innate immune response through TREM‐1 receptor inhibition
Cuvier, Valerie, Lorch, Ulrike, Witte, Stephan, Olivier, Aurelie, Gibot, Sebastien, Delor, Isabelle, Garaud, Jean‐Jacques, Derive, Marc, Salcedo‐Magguilli, Margarita
Published in British journal of clinical pharmacology (01.10.2018)
Published in British journal of clinical pharmacology (01.10.2018)
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Journal Article
Nangibotide in patients with septic shock: a Phase 2a randomized controlled clinical trial
François, Bruno, Wittebole, Xavier, Ferrer, Ricard, Mira, Jean-Paul, Dugernier, Thierry, Gibot, Sébastien, Derive, Marc, Olivier, Aurélie, Cuvier, Valérie, Witte, Stephan, Pickkers, Peter, Vandenhende, François, Garaud, Jean-Jacques, Sánchez, Miguel, Salcedo-Magguilli, Margarita, Laterre, Pierre-François
Published in Intensive care medicine (01.07.2020)
Published in Intensive care medicine (01.07.2020)
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Journal Article
Rationale and protocol for the efficacy, safety and tolerability of nangibotide in patients with septic shock (ASTONISH) phase IIb randomised controlled trial
Francois, Bruno, Lambden, Simon, Gibot, Sebastien, Derive, Marc, Olivier, Aurelie, Cuvier, Valerie, Witte, Stephan, Grouin, Jean-Marie, Garaud, Jean Jacques, Salcedo-Magguilli, Margarita, Levy, Mitchell, Laterre, Pierre-François
Published in BMJ open (07.07.2021)
Published in BMJ open (07.07.2021)
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항염 요법에 반응할 수 있는 대상체를 식별하기 위한 가용성 TREM-1 수준의 용도
DERIVE MARC, OLIVIER AURELIE, JOLLY LUCIE, GARAUD JEAN JACQUES, SALCEDO MAGGUILLI MARGARITA, BOUFENZER AMIR, CARRASCO KEVIN, KOCH MARTIN
Year of Publication 06.09.2021
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Year of Publication 06.09.2021
Patent
Prospective evaluation of the efficacy, safety, and optimal biomarker enrichment strategy for nangibotide, a TREM-1 inhibitor, in patients with septic shock (ASTONISH): a double-blind, randomised, controlled, phase 2b trial
François, Bruno, Lambden, Simon, Fivez, Tom, Gibot, Sebastien, Derive, Marc, Grouin, Jean-Marie, Salcedo-Magguilli, Margarita, Lemarié, Jérémie, De Schryver, Nicolas, Jalkanen, Ville, Hicheur, Tarik, Garaud, Jean-Jacques, Cuvier, Valérie, Ferrer, Ricard, Bestle, Morten, Pettilä, Ville, Mira, Jean-Paul, Bouisse, Camille, Mercier, Emmanuelle, Vermassen, Joris, Huberlant, Vincent, Vinatier, Isabelle, Anguel, Nadia, Levy, Mitchell, Laterre, Pierre-François
Published in The lancet respiratory medicine (01.10.2023)
Published in The lancet respiratory medicine (01.10.2023)
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Evaluation of the efficacy and safety of TREM-1 inhibition with nangibotide in patients with COVID-19 receiving respiratory support: the ESSENTIAL randomised, double-blind trial
François, Bruno, Lambden, Simon, Garaud, Jean-Jacques, Derive, Marc, Grouin, Jean-Marie, Asfar, Pierre, Darreau, Cédric, Mira, Jean-Paul, Quenot, Jean-Pierre, Lemarié, Jérémie, Mercier, Emmanuelle, Lacherade, Jean-Claude, Vinsonneau, Christophe, Fivez, Tom, Helms, Julie, Badie, Julio, Levy, Mitchell, Cuvier, Valérie, Salcedo-Magguilli, Margarita, Laszlo-Pouvreau, Anne-Lise, Laterre, Pierre-François, Gibot, Sébastien
Published in EClinicalMedicine (01.06.2023)
Published in EClinicalMedicine (01.06.2023)
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Journal Article
SOLUBLE TREM-1 AS A MARKER OF SEVERITY OR COMPLICATIONS FOR A SUBJECT SUFFERING FROM A CORONAVIRUS INFECTION
GARAUD, Jean-Jacques, JOLLY, Lucie, GIBOT, Sébastien, MOULIN, David, DE NOOIJER, Aline, SALCEDO-MAGGUILLI, Margarita, NETEA, Mihai, DERIVE, Marc
Year of Publication 31.08.2023
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Year of Publication 31.08.2023
Patent
SOLUBLE TREM-1 AS A MARKER OF SEVERITY OR COMPLICATIONS FOR A SUBJECT SUFFERING FROM A CORONAVIRUS INFECTION
GARAUD, Jean-Jacques, JOLLY, Lucie, GIBOT, Sébastien, MOULIN, David, DE NOOIJER, Aline, SALCEDO-MAGGUILLI, Margarita, NETEA, Mihai, DERIVE, Marc
Year of Publication 12.04.2023
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Year of Publication 12.04.2023
Patent
USE OF SOLUBLE TREM-1 LEVELS FOR IDENTIFYING SUBJECTS SUSCEPTIBLE TO RESPOND TO AN ANTI-INFLAMMATORY THERAPY
BOUFENZER, Amir, KOCH, Martin, CARRASCO, Kevin, GARAUD, Jean-Jacques, JOLLY, Lucie, OLIVIER, Aurelie, SALCEDO-MAGGUILLI, Margarita, DERIVE, Marc
Year of Publication 25.11.2021
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Year of Publication 25.11.2021
Patent
USE OF SOLUBLE TREM-1 LEVELS FOR IDENTIFYING SUBJECTS SUSCEPTIBLE TO RESPOND TO AN ANTI-INFLAMMATORY THERAPY
BOUFENZER, Amir, KOCH, Martin, CARRASCO, Kevin, GARAUD, Jean-Jacques, JOLLY, Lucie, OLIVIER, Aurelie, SALCEDO-MAGGUILLI, Margarita, DERIVE, Marc
Year of Publication 04.08.2021
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Year of Publication 04.08.2021
Patent
Use of soluble TREM-1 levels for identifying subjects susceptible to respond to an anti-inflammatory therapy
BOUFENZER, Amir, KOCH, Martin, CARRASCO, Kevin, GARAUD, Jean-Jacques, JOLLY, Lucie, OLIVIER, Aurelie, SALCEDO-MAGGUILLI, Margarita, DERIVE, Marc
Year of Publication 06.05.2021
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Year of Publication 06.05.2021
Patent
SOLUBLE TREM-1 AS A MARKER OF SEVERITY OR COMPLICATIONS FOR A SUBJECT SUFFERING FROM A CORONAVIRUS INFECTION
DERIVE, MARC, DE NOOIJER, ALINE, SALCEDO-MAGGUILLI, MARGARITA, JOLLY, LUCIE, GIBOT, SEBASTIEN, GARAUD, JEAN-JACQUES, NETEA, MIHAI, MOULIN, DAVID
Year of Publication 09.12.2021
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Year of Publication 09.12.2021
Patent
SOLUBLE TREM-1 AS A MARKER OF SEVERITY OR COMPLICATIONS FOR A SUBJECT SUFFERING FROM A CORONAVIRUS INFECTION
GARAUD, Jean-Jacques, JOLLY, Lucie, GIBOT, Sébastien, MOULIN, David, DE NOOIJER, Aline, SALCEDO-MAGGUILLI, Margarita, NETEA, Mihai, DERIVE, Marc
Year of Publication 09.12.2021
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Year of Publication 09.12.2021
Patent