Curcuma longa extract reduces inflammatory and oxidative stress biomarkers in osteoarthritis of knee: a four-month, double-blind, randomized, placebo-controlled trial
Srivastava, Shobhit, Saksena, Anil K., Khattri, Sanjay, Kumar, Santosh, Dagur, Raghubendra Singh
Published in Inflammopharmacology (01.12.2016)
Published in Inflammopharmacology (01.12.2016)
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Journal Article
Effect of Boswellia serrata extract on acute inflammatory parameters and tumor necrosis factor-α in complete Freund's adjuvant-induced animal model of rheumatoid arthritis
Kumar, Rajendra, Singh, Sarvesh, Saksena, Anil, Pal, Rishi, Jaiswal, Riddhi, Kumar, Rahul
Published in International journal of applied and basic medical research (01.04.2019)
Published in International journal of applied and basic medical research (01.04.2019)
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Journal Article
Discovery of (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor: A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection
Venkatraman, Srikanth, Bogen, Stéphane L, Arasappan, Ashok, Bennett, Frank, Chen, Kevin, Jao, Edwin, Liu, Yi-Tsung, Lovey, Raymond, Hendrata, Siska, Huang, Yuhua, Pan, Weidong, Parekh, Tejal, Pinto, Patrick, Popov, Veljko, Pike, Russel, Ruan, Sumei, Santhanam, Bama, Vibulbhan, Bancha, Wu, Wanli, Yang, Weiying, Kong, Jianshe, Liang, Xiang, Wong, Jesse, Liu, Rong, Butkiewicz, Nancy, Chase, Robert, Hart, Andrea, Agrawal, Sony, Ingravallo, Paul, Pichardo, John, Kong, Rong, Baroudy, Bahige, Malcolm, Bruce, Guo, Zhuyan, Prongay, Andrew, Madison, Vincent, Broske, Lisa, Cui, Xiaoming, Cheng, Kuo-Chi, Hsieh, Yunsheng, Brisson, Jean-Marc, Prelusky, Danial, Korfmacher, Walter, White, Ronald, Bogdanowich-Knipp, Susan, Pavlovsky, Anastasia, Bradley, Prudence, Saksena, Anil K, Ganguly, Ashit, Piwinski, John, Girijavallabhan, Viyyoor, Njoroge, F. George
Published in Journal of medicinal chemistry (05.10.2006)
Published in Journal of medicinal chemistry (05.10.2006)
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Journal Article
Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor
Arasappan, Ashok, Bennett, Frank, Bogen, Stephane L, Venkatraman, Srikanth, Blackman, Melissa, Chen, Kevin X, Hendrata, Siska, Huang, Yuhua, Huelgas, Regina M, Nair, Latha, Padilla, Angela I, Pan, Weidong, Pike, Russell, Pinto, Patrick, Ruan, Sumei, Sannigrahi, Mousumi, Velazquez, Francisco, Vibulbhan, Bancha, Wu, Wanli, Yang, Weiying, Saksena, Anil K, Girijavallabhan, Viyyoor, Shih, Neng-Yang, Kong, Jianshe, Meng, Tao, Jin, Yan, Wong, Jesse, McNamara, Paul, Prongay, Andrew, Madison, Vincent, Piwinski, John J, Cheng, Kuo-Chi, Morrison, Richard, Malcolm, Bruce, Tong, Xiao, Ralston, Robert, Njoroge, F. George
Published in ACS medicinal chemistry letters (13.05.2010)
Published in ACS medicinal chemistry letters (13.05.2010)
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Journal Article
Discovery of the HCV NS3/4A Protease Inhibitor (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key Steps in Structure-Based Optimization
Prongay, Andrew J, Guo, Zhuyan, Yao, Nanhua, Pichardo, John, Fischmann, Thierry, Strickland, Corey, Myers, Joseph, Weber, Patricia C, Beyer, Brian M, Ingram, Richard, Hong, Zhi, Prosise, Winifred W, Ramanathan, Lata, Taremi, S. Shane, Yarosh-Tomaine, Taisa, Zhang, Rumin, Senior, Mary, Yang, Rong-Sheng, Malcolm, Bruce, Arasappan, Ashok, Bennett, Frank, Bogen, Stephane L, Chen, Kevin, Jao, Edwin, Liu, Yi-Tsung, Lovey, Raymond G, Saksena, Anil K, Venkatraman, Srikanth, Girijavallabhan, Viyyoor, Njoroge, F. George, Madison, Vincent
Published in Journal of medicinal chemistry (17.05.2007)
Published in Journal of medicinal chemistry (17.05.2007)
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Journal Article
A comparative assessment of intranasal and oral dexmedetomidine for procedural sedation in pediatric dental patients
Patel, Vinod, Singh, Neerja, Saksena, Anil, Singh, Subash, Sonkar, S, Jolly, S
Published in Journal of the Indian Society of Pedodontics and Preventive Dentistry (01.10.2018)
Published in Journal of the Indian Society of Pedodontics and Preventive Dentistry (01.10.2018)
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Journal Article
Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations
Yi, MinKyung, Tong, Xiao, Skelton, Angela, Chase, Robert, Chen, Tong, Prongay, Andrew, Bogen, Stephane L, Saksena, Anil K, Njoroge, F George, Veselenak, Ronald L, Pyles, Richard B, Bourne, Nigel, Malcolm, Bruce A, Lemon, Stanley M
Published in The Journal of biological chemistry (24.03.2006)
Published in The Journal of biological chemistry (24.03.2006)
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Journal Article
The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir®: A change in direction in the search for a second generation HCV NS3 protease inhibitor
Bennett, Frank, Huang, Yuhua, Hendrata, Siska, Lovey, Raymond, Bogen, Stephane L., Pan, Weidong, Guo, Zhuyan, Prongay, Andrew, Chen, Kevin X., Arasappan, Ashok, Venkatraman, Srikanth, Velazquez, Francisco, Nair, Latha, Sannigrahi, Mousumi, Tong, Xiao, Pichardo, John, Cheng, Kuo-Chi, Girijavallabhan, Viyyoor M., Saksena, Anil K., Njoroge, F. George
Published in Bioorganic & medicinal chemistry letters (15.04.2010)
Published in Bioorganic & medicinal chemistry letters (15.04.2010)
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Journal Article
Toward the Back-Up of Boceprevir (SCH 503034): Discovery of New Extended P4-Capped Ketoamide Inhibitors of Hepatitis C Virus NS3 Serine Protease with Improved Potency and Pharmacokinetic Profiles
Bogen, Stéphane L, Pan, Weidong, Ruan, Sumei, Nair, Latha G, Arasappan, Ashok, Bennett, Frank, Chen, Kevin X, Jao, Edwin, Venkatraman, Srikanth, Vibulbhan, Bancha, Liu, Rong, Cheng, Kuo-Chi, Guo, Zhuyan, Tong, Xiao, Saksena, Anil K, Girijavallabhan, Viyyoor, Njoroge, F. George
Published in Journal of medicinal chemistry (25.06.2009)
Published in Journal of medicinal chemistry (25.06.2009)
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Journal Article
Toward Second Generation Hepatitis C Virus NS3 Serine Protease Inhibitors: Discovery of Novel P4 Modified Analogues with Improved Potency and Pharmacokinetic Profile
Arasappan, Ashok, Padilla, Angela I, Jao, Edwin, Bennett, Frank, Bogen, Stephane L, Chen, Kevin X, Pike, Russell E, Sannigrahi, Mousumi, Soares, Joana, Venkatraman, Srikanth, Vibulbhan, Bancha, Saksena, Anil K, Girijavallabhan, Viyyoor, Tong, Xiao, Cheng, Kuo-Chi, Njoroge, F. George
Published in Journal of medicinal chemistry (14.05.2009)
Published in Journal of medicinal chemistry (14.05.2009)
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Journal Article
Opinions, Attitudes, and Prescribing Practices of Oral Contraceptive Pills of General Practitioners and Gynecologists in India
Kumar, Sandeep, Dwivedi, Varsha, Pradeep, Yashodhara, Pakhare, Abhijeet, Agrawal, Girdhar Gopal, Saksena, Anil Kumar, Kumar, Vishwajeet
Published in Annals of the National Academy of Medical Sciences (India) (01.01.2022)
Published in Annals of the National Academy of Medical Sciences (India) (01.01.2022)
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Journal Article
Discovery of SCH446211 (SCH6): A New Ketoamide Inhibitor of the HCV NS3 Serine Protease and HCV Subgenomic RNA Replication
Bogen, Stéphane L, Arasappan, Ashok, Bennett, Frank, Chen, Kevin, Jao, Edwin, Liu, Yi-Tsung, Lovey, Raymond G, Venkatraman, Srikanth, Pan, Weidong, Parekh, Tajel, Pike, Russel E, Ruan, Sumei, Liu, Rong, Baroudy, Bahige, Agrawal, Sony, Chase, Robert, Ingravallo, Paul, Pichardo, John, Prongay, Andrew, Brisson, Jean-Marc, Hsieh, Tony Y, Cheng, Kuo-Chi, Kemp, Scott J, Levy, Odile E, Lim-Wilby, Marguerita, Tamura, Susan Y, Saksena, Anil K, Girijavallabhan, Viyyoor, Njoroge, F. George
Published in Journal of medicinal chemistry (04.05.2006)
Published in Journal of medicinal chemistry (04.05.2006)
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Journal Article
Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048 ( 1), and the discovery of posaconazole [Sch 56592; 2 or ( S, S)- 5]
Bennett, Frank, Saksena, Anil K., Lovey, Raymond G., Liu, Yi-Tsung, Patel, Naginbhai M., Pinto, Patrick, Pike, Russel, Jao, Edwin, Girijavallabhan, Viyyoor M., Ganguly, Ashit K., Loebenberg, David, Wang, Haiyan, Cacciapuoti, Anthony, Moss, Eugene, Menzel, Fred, Hare, Roberta S., Nomeir, Amin
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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Journal Article
Depeptidization efforts on P3–P2′ α-ketoamide inhibitors of HCV NS3-4A serine protease: Effect on HCV replicon activity
Bogen, Stéphane L., Ruan, Sumei, Liu, Rong, Agrawal, Sony, Pichardo, John, Prongay, Andrew, Baroudy, Bahige, Saksena, Anil K., Girijavallabhan, Viyyoor, Njoroge, F. George
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
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Journal Article
Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034
Madison, Vincent, Prongay, Andrew J., Guo, Zhuyan, Yao, Nanhua, Pichardo, John, Fischmann, Thierry, Strickland, Corey, Myers Jr, Joseph, Weber, Patricia C., Beyer, Brian M., Ingram, Richard, Hong, Zhi, Prosise, Winifred W., Ramanathan, Lata, Taremi, S. Shane, Yarosh-Tomaine, Taisa, Zhang, Rumin, Senior, Mary, Yang, Rong-Sheng, Malcolm, Bruce, Arasappan, Ashok, Bennett, Frank, Bogen, Stephane L., Chen, Kevin, Jao, Edwin, Liu, Yi-Tsung, Lovey, Raymond G., Saksena, Anil K., Venkatraman, Srikanth, Girijavallabhan, Viyyoor, Njoroge, F. George
Published in Journal of synchrotron radiation (01.05.2008)
Published in Journal of synchrotron radiation (01.05.2008)
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Journal Article
Novel inhibitors of the hepatitis C virus NS3 proteinase
Bennett, Frank, Liu, Yi-Tsung, Saksena, Anil K., Arasappan, Ashok, Butkiewicz, Nancy, Dasmahapatra, Bimalendu, Pichardo, John S., Njoroge, F. George, Patel, Naginbhai M., Huang, Yuhua, Yang, Xiaozheng
Published in Bioorganic & medicinal chemistry letters (01.10.2005)
Published in Bioorganic & medicinal chemistry letters (01.10.2005)
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Journal Article
Multiple-stage mass spectrometric analysis of complex oligosaccharide antibiotics (everninomicins) in a quadrupole ion trap
Chen, Guodong, Pramanik, Birendra N, Bartner, Peter L, Saksena, Anil K, Gross, Michael L
Published in Journal of the American Society for Mass Spectrometry (01.11.2002)
Published in Journal of the American Society for Mass Spectrometry (01.11.2002)
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