In Vitro Activities of a New Lipopeptide Antifungal Agent, FK463, against a Variety of Clinically Important Fungi
TAWARA, S, IKEDA, F, KAWABATA, K, TAKASUGI, H, SAKANE, K, TANAKA, H, MATSUMOTO, F, KUWAHARA, S, MAKI, K, MORISHITA, Y, OTOMO, K, TERATANI, N, GOTO, T, TOMISHIMA, M, OHKI, H, YAMADA, A
Published in Antimicrobial Agents and Chemotherapy (01.01.2000)
Published in Antimicrobial Agents and Chemotherapy (01.01.2000)
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Design, Synthesis and Biological Evaluation of a Novel Series of Potent, Orally Active Adenosine A1 Receptor Antagonists with High Blood-Brain Barrier Permeability
KURODA, Satoru, TAKAMURA, Fujiko, TENDA, Yoshiyuki, ITANI, Hiromichi, TOMISHIMA, Yasuyo, AKAHANE, Atsushi, SAKANE, Kazuo
Published in Chemical & pharmaceutical bulletin (01.08.2001)
Published in Chemical & pharmaceutical bulletin (01.08.2001)
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Discovery of FR166124, a novel water-soluble pyrazolo-[1,5-a]pyridine adenosine A1 receptor antagonist
KURODA, S, AKAHANE, A, ITANI, H, NISHIMURA, S, DURKIN, K, KINOSHITA, T, TENDA, Y, SAKANE, K
Published in Bioorganic & medicinal chemistry letters (19.07.1999)
Published in Bioorganic & medicinal chemistry letters (19.07.1999)
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New reagents for controlled release of nitric oxide. Structure-stability relationships
Kato, Masayuki, Nishino, Shigetaka, Ohno, Mitsuko, Fukuyama, Shinichi, Kita, Yasuhiro, Hirasawa, Yoshimi, Nakanishi, Isao, Takasugi, Hisashi, Sakane, Kazuo
Published in Bioorganic & medicinal chemistry letters (01.01.1996)
Published in Bioorganic & medicinal chemistry letters (01.01.1996)
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Synthesis of the water-soluble adenosine A1 receptor antagonist FR166124 through a novel sequential Horner-Emmons / isomerization reaction
Kuroda, Satoru, Akahane, Atsushi, Itani, Hiromichi, Nishimura, Shintaro, Durkin, Kieran, Kinoshita, Takayoshi, Nakanishi, Isao, Sakane, Kazuo
Published in Tetrahedron (01.08.1999)
Published in Tetrahedron (01.08.1999)
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Novel adenosine A 1 receptor antagonists. Synthesis and structure–activity relationships of a novel series of 3-(2-cyclohexenyl-3-oxo-2,3-dihydropyridazin-6-yl)-2-phenylpyrazolo[1,5- a ]pyridines
Kuroda, Satoru, Akahane, Atsushi, Itani, Hiromichi, Nishimura, Shintaro, Durkin, Kieran, Tenda, Yoshiyuki, Sakane, Kazuo
Published in Bioorganic & medicinal chemistry (01.01.2000)
Published in Bioorganic & medicinal chemistry (01.01.2000)
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A novel synthesis of the pyrazolo[1,5- a]quinoline ring system. New N1-C2 bridged DNA gyrase inhibitors via a novel tandem 1,4-conjugate addition-Michael [3+2] annulation process
Barrett, David, Sasaki, Hiroshi, Kinoshita, Takayoshi, Fujikawa, Akihiko, Sakane, Kazuo
Published in Tetrahedron (01.06.1996)
Published in Tetrahedron (01.06.1996)
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FR109615, A NEW ANTIFUNGAL ANTIBIOTIC FROM STREPTOMYCES SETONII: TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITY
IWAMOTO, TOSHIRO, TSUJII, EISAKU, EZAKI, MASAMI, FUJIE, AKIHIKO, HASHIMOTO, SEIJI, OKUHARA, MASAKUNI, KOHSAKA, MASANOBU, IMANAKA, HIROSHI, KAWABATA, KOHJI, INAMOTO, YOSHIKO, SAKANE, KAZUO
Published in Journal of antibiotics (1990)
Published in Journal of antibiotics (1990)
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Alkylation of 1-[N-(Hydroxymethyl)-N-methylamino]-4-quinolones. An Improved Preparation of Intermediates for Novel Potent Tricyclic Quinolone Antibacterial Agents
Barrett, David, Sasaki, Hiroshi, Kinoshita, Takayoshi, Tsutsumi, Hideo, Sakane, Kazuo
Published in Bulletin of the Chemical Society of Japan (01.05.1996)
Published in Bulletin of the Chemical Society of Japan (01.05.1996)
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Synthesis and Biological Properties of a Novel Cephalosporin FR86521 Having Potent Activity Against Methicillin-resistant Staphylococcus aureus (MRSA)
KISHI, KOHEI, OHKI, HIDENORI, OKUDA, SHINYA, KAWABATA, KOHJI, SAKANE, KAZUO, MATSUMOTO, YOSHIMI, MATSUMOTO, SATORU, TAWARA, SHUICHI
Published in Journal of antibiotics (1999)
Published in Journal of antibiotics (1999)
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Studies on 3'-Quaternary Ammonium Cephalosporins II. Synthesis and Antibacterial Activity of 7.BETA.-((Z)-2-(2-Aminothiazol-4-yl)-2- methoxyiminoacetamido)cephalosporin Derivatives Bearing Various Quaternary Ammonium Methyl Groups at the 3 Position
OHKI, HIDENORI, KAWABATA, KOHJI, OKUDA, SHINYA, KAMIMURA, TOSHIAKI, SAKANE, KAZUO
Published in Journal of antibiotics (1995)
Published in Journal of antibiotics (1995)
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Studies on β-Lactam Antibiotics: Synthesis and Antibacterial Activity of Novel C-3 Alkyne-substituted Cephalosporins
BARRETT, DAVID, TERASAWA, TAKESHI, OKUDA, SHINYA, KAWABATA, KOHJI, YASUDA, NOBUYOSHI, KAMIMURA, TOSHIAKI, SAKANE, KAZUO, TAKAYA, TAKAO
Published in Journal of antibiotics (01.01.1997)
Published in Journal of antibiotics (01.01.1997)
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Epimerization Induced by a Remote Cationic Center in Potent New Carbapenems
AZAMI, Hidenori, BARRETT, David, CHIBA, Toshiyuki, FUJIKAWA, Akihiko, SAKANE, Kazuo, SHIRAI, Fumiyuki
Published in Chemical & pharmaceutical bulletin (01.01.1997)
Published in Chemical & pharmaceutical bulletin (01.01.1997)
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Synthesis and antifungal activity of FR 109615 analogs
OHKI, HIDENORI, INAMOTO, YOSHIKO, KAWABATA, KOHJI, KAMIMURA, TOSHIAKI, SAKANE, KAZUO
Published in Journal of antibiotics (1991)
Published in Journal of antibiotics (1991)
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STUDIES ON β-LACTAM ANTIBIOTICS: XIX. STRUCTURE-ACTIVITY RELATIONSHIPS OF CEPHALOSPORINS HAVING A THIADIAZOLYLTHIOMETHYL GROUP AT THE C-3 SIDE CHAIN
INAMOTO, YOSHIKO, GOTO, JIRO, SAKANE, KAZUO, KAMIMURA, TOSHIAKI, TAKAYA, TAKAO
Published in Journal of antibiotics (1991)
Published in Journal of antibiotics (1991)
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