Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cells
Mimitou, Eleni P., Lareau, Caleb A., Chen, Kelvin Y., Zorzetto-Fernandes, Andre L., Hao, Yuhan, Takeshima, Yusuke, Luo, Wendy, Huang, Tse-Shun, Yeung, Bertrand Z., Papalexi, Efthymia, Thakore, Pratiksha I., Kibayashi, Tatsuya, Wing, James Badger, Hata, Mayu, Satija, Rahul, Nazor, Kristopher L., Sakaguchi, Shimon, Ludwig, Leif S., Sankaran, Vijay G., Regev, Aviv, Smibert, Peter
Published in Nature biotechnology (01.10.2021)
Published in Nature biotechnology (01.10.2021)
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Journal Article
Foxp3⁺ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
Onishi, Yasushi, Fehervari, Zoltan, Yamaguchi, Tomoyuki, Sakaguchi, Shimon
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.2008)
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Journal Article
New Treg cell-based therapies of autoimmune diseases: towards antigen-specific immune suppression
Mikami, Norihisa, Kawakami, Ryoji, Sakaguchi, Shimon
Published in Current opinion in immunology (01.12.2020)
Published in Current opinion in immunology (01.12.2020)
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Journal Article
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
Klocke, Katrin, Sakaguchi, Shimon, Holmdahl, Rikard, Wing, Kajsa
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.2016)
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Journal Article
Regulatory T cells: how do they suppress immune responses?
Sakaguchi, Shimon, Wing, Kajsa, Onishi, Yasushi, Prieto-Martin, Paz, Yamaguchi, Tomoyuki
Published in International immunology (01.10.2009)
Published in International immunology (01.10.2009)
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Journal Article
Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation
Matsumoto, Masanori, Baba, Akemi, Yokota, Takafumi, Nishikawa, Hiroyoshi, Ohkawa, Yasuyuki, Kayama, Hisako, Kallies, Axel, Nutt, Stephen L., Sakaguchi, Shimon, Takeda, Kiyoshi, Kurosaki, Tomohiro, Baba, Yoshihiro
Published in Immunity (Cambridge, Mass.) (18.12.2014)
Published in Immunity (Cambridge, Mass.) (18.12.2014)
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Journal Article
Anti-CCR4 mAb selectively depletes effector-type FoxP3⁺CD4⁺ regulatory T cells, evoking antitumor immune responses in humans
Sugiyama, Daisuke, Nishikawa, Hiroyoshi, Maeda, Yuka, Nishioka, Megumi, Tanemura, Atsushi, Katayama, Ichiro, Ezoe, Sachiko, Kanakura, Yuzuru, Sato, Eiichi, Fukumori, Yasuo, Karbach, Julia, Jäger, Elke, Sakaguchi, Shimon
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (29.10.2013)
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Journal Article
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis
Hirota, Keiji, Hashimoto, Motomu, Ito, Yoshinaga, Matsuura, Mayumi, Ito, Hiromu, Tanaka, Masao, Watanabe, Hitomi, Kondoh, Gen, Tanaka, Atsushi, Yasuda, Keiko, Kopf, Manfred, Potocnik, Alexandre J., Stockinger, Brigitta, Sakaguchi, Noriko, Sakaguchi, Shimon
Published in Immunity (Cambridge, Mass.) (19.06.2018)
Published in Immunity (Cambridge, Mass.) (19.06.2018)
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Journal Article
VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data
Yasumizu, Yoshiaki, Hara, Atsushi, Sakaguchi, Shimon, Ohkura, Naganari
Published in Bioinformatics (05.10.2020)
Published in Bioinformatics (05.10.2020)
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Journal Article
Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota
Atarashi, Koji, Tanoue, Takeshi, Oshima, Kenshiro, Suda, Wataru, Nagano, Yuji, Nishikawa, Hiroyoshi, Fukuda, Shinji, Saito, Takuro, Narushima, Seiko, Hase, Koji, Kim, Sangwan, Fritz, Joëlle V., Wilmes, Paul, Ueha, Satoshi, Matsushima, Kouji, Ohno, Hiroshi, Olle, Bernat, Sakaguchi, Shimon, Taniguchi, Tadatsugu, Morita, Hidetoshi, Hattori, Masahira, Honda, Kenya
Published in Nature (London) (08.08.2013)
Published in Nature (London) (08.08.2013)
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Journal Article