T-Cells Expressing a Highly Potent PRAME-Specific T-Cell Receptor in Combination with a Chimeric PD1-41BB Co-Stimulatory Receptor Show a Favorable Preclinical Safety Profile and Strong Anti-Tumor Reactivity
Sailer, Nadja, Fetzer, Ina, Salvermoser, Melanie, Braun, Monika, Brechtefeld, Doris, Krendl, Christian, Geiger, Christiane, Mutze, Kathrin, Noessner, Elfriede, Schendel, Dolores J, Bürdek, Maja, Wilde, Susanne, Sommermeyer, Daniel
Published in Cancers (14.04.2022)
Published in Cancers (14.04.2022)
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Journal Article
614 Co-stimulation via PD1–41BB chimeric switch receptor enhances function of TCR-T cells in an immune-suppressive milieu and under chronic antigen stimulation
Salvermoser, Melanie, Gerget, Maria, Hasselmann, Franziska, Noessner, Elfriede, Ellinger, Christian, Braun, Monika, Schendel, Dolores, Sommermeyer, Daniel, Sailer, Nadja
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
Abstract 3231: The chimeric co-stimulatory receptor PD1-41BB enhances the function of T cell receptor (TCR)-modified T cells targeting solid tumors
Sailer, Nadja, Salvermoser, Melanie, Gerget, Maria, Thome, Sarah, Fischbeck, Angelika J., Ruehland, Svenja, Olguín-Contreras, Luis F., Buerdek, Maja, Ellinger, Christian, Noessner, Elfriede, Schendel, Dolores J., Kehler, Patrik
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 1521: Combining a PRAME-specific TCR showing potent in vitro and in vivo anti-tumor reactivity and a favorable preclinical safety profile with a PD1-41BB switch receptor results in highly efficient T cells
Fetzer, Ina, Sailer, Nadja, Salvermoser, Melanie, Weis, Manon, Krendl, Christian, Bürdek, Maja, Brechtefeld, Doris, Rampp, Isabella, Rydzek-Wiesner, Julian, Braun, Monika, Ellinger, Christian, Geiger, Christiane, Sommermeyer, Daniel, Wilde, Susanne
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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PRAME 특이적 T 세포 수용체 및 키메라 공동 자극 수용체의 조합
SALVERMOSER MELANIE, BUERDEK MAJA, SOMMERMEYER DANIEL, SAILER NADJA, WILDE SUSANNE, FETZER INA
Year of Publication 12.01.2024
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Year of Publication 12.01.2024
Patent
Abstract 2749: iPSC-derived natural killer cells as the front-runner program of the EVO cells Oncology platform: From inception to translational validation using patient samples
Esquerré, Michael, Holtzinger, Audrey, Pichery, Mélanie, Pfaender, Stefanie, Yumlu, Saniye, Richter, Mandy, Betous, Delphine, Bombarde, Oriane, Gador, Mylène, Sailer, Nadja, Paillasse, Michael, Ysebaert, Loïc, Despas, Fabien, Austen, Matthias, Scheel, Andreas, Dangl, Markus
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Generation of tumor antigen-specific CD4+ and CD8+ T cells by simultaneous MHC-I and -II epitope presentation in vitro and in vivo
Wehner, Carina, Ellinger, Christian, Raffegerst, Silke, Wilde, Susanne, Mosetter, Barbara, Eckl, Judith, Frankenberger, Bernhard, Weis, Manon, Longinotti, Giulia, Sailer, Nadja, Schendel, Dolores J, Milosevic, Slavoljub
Published in Journal for immunotherapy of cancer (06.11.2014)
Published in Journal for immunotherapy of cancer (06.11.2014)
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Journal Article
COMBINATION OF PRAME SPECIFIC T CELL RECEPTORS AND CHIMERIC CO-STIMULATORY RECEPTORS
SAILER, Nadja, SOMMERMEYER, Daniel, WILDE, Susanne, FETZER, Ina, BÜRDEK, Maja, SALVERMOSER, Melanie
Year of Publication 22.08.2024
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Year of Publication 22.08.2024
Patent
COMBINATION OF PRAME SPECIFIC T CELL RECEPTORS AND CHIMERIC CO-STIMULATORY RECEPTORS
SAILER, Nadja, SOMMERMEYER, Daniel, WILDE, Susanne, FETZER, Ina, BÜRDEK, Maja, SALVERMOSER, Melanie
Year of Publication 13.03.2024
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Year of Publication 13.03.2024
Patent
COMBINATION OF PRAME SPECIFIC T CELL RECEPTORS AND CHIMERIC CO-STIMULATORY RECEPTORS
SAILER, Nadja, SOMMERMEYER, Daniel, WILDE, Susanne, FETZER, Ina, BÜRDEK, Maja, SALVERMOSER, Melanie
Year of Publication 16.11.2023
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Year of Publication 16.11.2023
Patent
COMBINATION OF PRAME SPECIFIC T CELL RECEPTORS AND CHIMERIC CO-STIMULATORY RECEPTORS
BURDEK, MAJA, SALVERMOSER, MELANIE, FETZER, INA, SOMMERMEYER, DANIEL, WILDE, SUSANNE, SAILER, NADJA
Year of Publication 10.11.2022
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Year of Publication 10.11.2022
Patent
COMBINATION OF PRAME SPECIFIC T CELL RECEPTORS AND CHIMERIC CO-STIMULATORY RECEPTORS
SAILER, Nadja, SOMMERMEYER, Daniel, WILDE, Susanne, FETZER, Ina, BÜRDEK, Maja, SALVERMOSER, Melanie
Year of Publication 10.11.2022
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Year of Publication 10.11.2022
Patent