Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids
Grein, Fabian, Müller, Anna, Scherer, Katharina M., Liu, Xinliang, Ludwig, Kevin C., Klöckner, Anna, Strach, Manuel, Sahl, Hans-Georg, Kubitscheck, Ulrich, Schneider, Tanja
Published in Nature communications (19.03.2020)
Published in Nature communications (19.03.2020)
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Journal Article
Insights into the Mode of Action of Chitosan as an Antibacterial Compound
Raafat, Dina, von Bargen, Kristine, Haas, Albert, Sahl, Hans-Georg
Published in Applied and Environmental Microbiology (01.06.2008)
Published in Applied and Environmental Microbiology (01.06.2008)
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Journal Article
Small cationic antimicrobial peptides delocalize peripheral membrane proteins
Wenzel, Michaela, Chiriac, Alina Iulia, Otto, Andreas, Zweytick, Dagmar, May, Caroline, Schumacher, Catherine, Gust, Ronald, Albada, H Bauke, Penkova, Maya, Kraemer, Ute, Erdmann, Ralf, Metzler-Nolte, Nils, Straus, Suzana K, Bremer, Erhard, Becher, Dorte, Brotz-Oesterhelt, Heike, Sahl, Hans-Georg, Bandow, Julia Elisabeth
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2014)
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Journal Article
Metagenome Mining Reveals Polytheonamides as Posttranslationally Modified Ribosomal Peptides
Freeman, Michael F., Gurgui, Cristian, Helf, Maximilian J., Morinaka, Brandon I., Uria, Agustinus R., Oldham, Neil J., Sahl, Hans-Georg, Matsunaga, Shigeki, Piel, Jörn
Published in Science (American Association for the Advancement of Science) (19.10.2012)
Published in Science (American Association for the Advancement of Science) (19.10.2012)
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Journal Article
Human β-Defensin 3 Inhibits Cell Wall Biosynthesis in Staphylococci
Sass, Vera, Schneider, Tanja, Wilmes, Miriam, Körner, Christian, Tossi, Alessandro, Novikova, Natalia, Shamova, Olga, Sahl, Hans-Georg
Published in Infection and Immunity (01.06.2010)
Published in Infection and Immunity (01.06.2010)
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Journal Article
Antibiotic acyldepsipeptides activate ClpP peptidase to degrade the cell division protein FtsZ
Sass, Peter, Josten, Michaele, Famulla, Kirsten, Schiffer, Guido, Sahl, Hans-Georg, Hamoen, Leendert, Brötz-Oesterhelt, Heike
Published in Proceedings of the National Academy of Sciences - PNAS (18.10.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (18.10.2011)
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Journal Article
Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II
Schneider, Tanja, Kruse, Thomas, Wimmer, Reinhard, Wiedemann, Imke, Sass, Vera, Pag, Ulrike, Jansen, Andrea, Nielsen, Allan K, Mygind, Per H, Raventós, Dorotea S, Neve, Søren, Ravn, Birthe, Bonvin, Alexandre M.J.J, De Maria, Leonardo, Andersen, Anders S, Gammelgaard, Lora K, Sahl, Hans-Georg, Kristensen, Hans-Henrik
Published in Science (American Association for the Advancement of Science) (28.05.2010)
Published in Science (American Association for the Advancement of Science) (28.05.2010)
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Journal Article
Analysis of the Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrum of Staphylococcus aureus Identifies Mutations That Allow Differentiation of the Main Clonal Lineages
Josten, Michaele, Reif, Marion, Szekat, Christiane, Al-Sabti, Nahed, Roemer, Terry, Sparbier, Katrin, Kostrzewa, Markus, Rohde, Holger, Sahl, Hans-Georg, Bierbaum, Gabriele
Published in Journal of Clinical Microbiology (01.06.2013)
Published in Journal of Clinical Microbiology (01.06.2013)
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Journal Article
Production of the novel two-peptide lantibiotic lichenicidin by Bacillus licheniformis DSM 13
Dischinger, Jasmin, Josten, Michaele, Szekat, Christiane, Sahl, Hans-Georg, Bierbaum, Gabriele
Published in PloS one (26.08.2009)
Published in PloS one (26.08.2009)
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Journal Article
Lipid Requirements for the Enzymatic Activity of MraY Translocases and in Vitro Reconstitution of the Lipid II Synthesis Pathway
Henrich, Erik, Ma, Yi, Engels, Ina, Münch, Daniela, Otten, Christian, Schneider, Tanja, Henrichfreise, Beate, Sahl, Hans-Georg, Dötsch, Volker, Bernhard, Frank
Published in The Journal of biological chemistry (29.01.2016)
Published in The Journal of biological chemistry (29.01.2016)
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Journal Article
Failures in Clinical Treatment of Staphylococcus aureus Infection with Daptomycin Are Associated with Alterations in Surface Charge, Membrane Phospholipid Asymmetry, and Drug Binding
JONES, Tiffanny, YEAMAN, Michael R, SAKOULAS, George, YANG, Soo-Jin, PROCTOR, Richard A, SAHL, Hans-Georg, SCHRENZEL, Jacques, XIONG, Yan Q, BAYER, Arnold S
Published in Antimicrobial Agents and Chemotherapy (01.01.2008)
Published in Antimicrobial Agents and Chemotherapy (01.01.2008)
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Journal Article
The mode of action of the lantibiotic lacticin 3147 – a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II
Wiedemann, Imke, Böttiger, Tim, Bonelli, Raquel R., Wiese, Andre, Hagge, Sven O., Gutsmann, Thomas, Seydel, Ulrich, Deegan, Lucy, Hill, Colin, Ross, Paul, Sahl, Hans‐Georg
Published in Molecular microbiology (01.07.2006)
Published in Molecular microbiology (01.07.2006)
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