Gene therapy for neurological disorders: progress and prospects
Deverman, Benjamin E., Ravina, Bernard M., Bankiewicz, Krystof S., Paul, Steven M., Sah, Dinah W. Y.
Published in Nature reviews. Drug discovery (01.09.2018)
Published in Nature reviews. Drug discovery (01.09.2018)
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Journal Article
Blockade of Nogo-66, Myelin-Associated Glycoprotein, and Oligodendrocyte Myelin Glycoprotein by Soluble Nogo-66 Receptor Promotes Axonal Sprouting and Recovery after Spinal Injury
Li, Shuxin, Liu, Betty P, Budel, Stephane, Li, Mingwei, Ji, Benxiu, Walus, Lee, Li, Weiwei, Jirik, Adrienna, Rabacchi, Sylvia, Choi, Eugene, Worley, Dane, Sah, Dinah W. Y, Pepinsky, Blake, Lee, Daniel, Relton, Jane, Strittmatter, Stephen M
Published in The Journal of neuroscience (17.11.2004)
Published in The Journal of neuroscience (17.11.2004)
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Journal Article
Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
Iwamoto, Naoki, Butler, David C D, Svrzikapa, Nenad, Mohapatra, Susovan, Zlatev, Ivan, Sah, Dinah W Y, Meena, Standley, Stephany M, Lu, Genliang, Apponi, Luciano H, Frank-Kamenetsky, Maria, Zhang, Jason Jingxin, Vargeese, Chandra, Verdine, Gregory L
Published in Nature biotechnology (01.09.2017)
Published in Nature biotechnology (01.09.2017)
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Journal Article
Widespread suppression of huntingtin with convection-enhanced delivery of siRNA
Stiles, David K., Zhang, Zhiming, Ge, Pei, Nelson, Brian, Grondin, Richard, Ai, Yi, Hardy, Peter, Nelson, Peter T., Guzaev, Andrei P., Butt, Mark T., Charisse, Klaus, Kosovrasti, Verbena, Tchangov, Lubomir, Meys, Michael, Maier, Martin, Nechev, Lubomir, Manoharan, Muthiah, Kaemmerer, William F., Gwost, Douglas, Stewart, Gregory R., Gash, Don M., Sah, Dinah W.Y.
Published in Experimental neurology (01.01.2012)
Published in Experimental neurology (01.01.2012)
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Journal Article
RNAi therapeutics: a potential new class of pharmaceutical drugs
Sah, Dinah W Y, Bumcrot, David, Manoharan, Muthiah, Koteliansky, Victor
Published in Nature chemical biology (01.12.2006)
Published in Nature chemical biology (01.12.2006)
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Journal Article
Gene therapy for neurological disorders: progress and prospects
Deverman, Benjamin E, Ravina, Bernard M, Bankiewicz, Krystof S, Paul, Steven M, Sah, Dinah W Y
Published in Nature reviews. Drug discovery (01.10.2018)
Published in Nature reviews. Drug discovery (01.10.2018)
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Journal Article
Lipophilic siRNAs mediate efficient gene silencing in oligodendrocytes with direct CNS delivery
Chen, Qingmin, Butler, David, Querbes, William, Pandey, Rajendra K., Ge, Pei, Maier, Martin A., Zhang, Ligang, Rajeev, Kallanthottathil G., Nechev, Lubomir, Kotelianski, Victor, Manoharan, Muthiah, Sah, Dinah W.Y.
Published in Journal of controlled release (01.06.2010)
Published in Journal of controlled release (01.06.2010)
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Journal Article
Lipid-like materials for low-dose, in vivo gene silencing
Love, Kevin T, Mahon, Kerry P, Levins, Christopher G, Whitehead, Kathryn A, Querbes, William, Dorkin, J. Robert, Qin, June, Cantley, William, Qin, Liu Liang, Racie, Timothy, Frank-Kamenetsky, Maria, Yip, Ka Ning, Alvarez, Rene, Sah, Dinah W.Y, de Fougerolles, Antonin, Fitzgerald, Kevin, Koteliansky, Victor, Akinc, Akin, Langer, Robert, Anderson, Daniel G
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2010)
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Journal Article
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
Anderson, Daniel G, Akinc, Akin, Zumbuehl, Andreas, Goldberg, Michael, Leshchiner, Elizaveta S, Busini, Valentina, Hossain, Naushad, Bacallado, Sergio A, Nguyen, David N, Fuller, Jason, Alvarez, Rene, Borodovsky, Anna, Borland, Todd, Constien, Rainer, de Fougerolles, Antonin, Dorkin, J Robert, Narayanannair Jayaprakash, K, Jayaraman, Muthusamy, John, Matthias, Koteliansky, Victor, Manoharan, Muthiah, Nechev, Lubomir, Qin, June, Racie, Timothy, Raitcheva, Denitza, Rajeev, Kallanthottathil G, Sah, Dinah W Y, Soutschek, Jürgen, Toudjarska, Ivanka, Vornlocher, Hans-Peter, Zimmermann, Tracy S, Langer, Robert
Published in Nature biotechnology (01.05.2008)
Published in Nature biotechnology (01.05.2008)
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Journal Article
Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis
Coelho, Teresa, Adams, David, Silva, Ana, Lozeron, Pierre, Hawkins, Philip N, Mant, Timothy, Perez, Javier, Chiesa, Joseph, Warrington, Steve, Tranter, Elizabeth, Munisamy, Malathy, Falzone, Rick, Harrop, Jamie, Cehelsky, Jeffrey, Bettencourt, Brian R, Geissler, Mary, Butler, James S, Sehgal, Alfica, Meyers, Rachel E, Chen, Qingmin, Borland, Todd, Hutabarat, Renta M, Clausen, Valerie A, Alvarez, Rene, Fitzgerald, Kevin, Gamba-Vitalo, Christina, Nochur, Saraswathy V, Vaishnaw, Akshay K, Sah, Dinah W.Y, Gollob, Jared A, Suhr, Ole B
Published in The New England journal of medicine (29.08.2013)
Published in The New England journal of medicine (29.08.2013)
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Journal Article
Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
Akinc, Akin, Querbes, William, De, Soma, Qin, June, Frank-Kamenetsky, Maria, Jayaprakash, K. Narayanannair, Jayaraman, Muthusamy, Rajeev, Kallanthottathil G, Cantley, William L, Dorkin, J Robert, Butler, James S, Qin, LiuLiang, Racie, Timothy, Sprague, Andrew, Fava, Eugenio, Zeigerer, Anja, Hope, Michael J, Zerial, Marino, Sah, Dinah WY, Fitzgerald, Kevin, Tracy, Mark A, Manoharan, Muthiah, Koteliansky, Victor, Fougerolles, Antonin de, Maier, Martin A
Published in Molecular therapy (01.07.2010)
Published in Molecular therapy (01.07.2010)
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Journal Article
Targeting the Nogo Receptor to Treat Central Nervous System Injuries
Lee, Daniel H. S, Strittmatter, Stephen M, Sah, Dinah W. Y
Published in Nature reviews. Drug discovery (01.11.2003)
Published in Nature reviews. Drug discovery (01.11.2003)
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Journal Article
Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma
Inda, Maria-del-Mar, Bonavia, Rudy, Mukasa, Akitake, Narita, Yoshitaka, Sah, Dinah W Y, Vandenberg, Scott, Brennan, Cameron, Johns, Terrance G, Bachoo, Robert, Hadwiger, Philipp, Tan, Pamela, Depinho, Ronald A, Cavenee, Webster, Furnari, Frank
Published in Genes & development (15.08.2010)
Published in Genes & development (15.08.2010)
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Journal Article
siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells
Hewett, Jeffrey W., Nery, Flávia C., Niland, Brian, Ge, Pei, Tan, Pamela, Hadwiger, Philipp, Tannous, Bakhos A., Sah, Dinah W.Y., Breakefield, Xandra O.
Published in Human molecular genetics (15.05.2008)
Published in Human molecular genetics (15.05.2008)
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Journal Article
Artemin induced functional recovery and reinnervation after partial nerve injury
Wang, Ruizhong, Rossomando, Anthony, Sah, Dinah W.Y., Ossipov, Michael H., King, Tamara, Porreca, Frank
Published in Pain (Amsterdam) (01.03.2014)
Published in Pain (Amsterdam) (01.03.2014)
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Journal Article
Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury
Cariani, Peter, Vanderah, Todd W, Porreca, Frank, Wang, Ruizhong, Frank, Eric, Ossipov, Michael H, Harvey, Pamela, King, Tamara, Rossomando, Anthony J, Sah, Dinah W Y
Published in Nature neuroscience (01.04.2008)
Published in Nature neuroscience (01.04.2008)
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Journal Article
Tissue-specific gene silencing monitored in circulating RNA
Sehgal, Alfica, Chen, Qingmin, Gibbings, Derrick, Sah, Dinah W Y, Bumcrot, David
Published in RNA (Cambridge) (01.02.2014)
Published in RNA (Cambridge) (01.02.2014)
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Journal Article
First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement
Tabernero, Josep, Shapiro, Geoffrey I, LoRusso, Patricia M, Cervantes, Andres, Schwartz, Gary K, Weiss, Glen J, Paz-Ares, Luis, Cho, Daniel C, Infante, Jeffrey R, Alsina, Maria, Gounder, Mrinal M, Falzone, Rick, Harrop, Jamie, White, Amy C Seila, Toudjarska, Iva, Bumcrot, David, Meyers, Rachel E, Hinkle, Gregory, Svrzikapa, Nenad, Hutabarat, Renta M, Clausen, Valerie A, Cehelsky, Jeffrey, Nochur, Saraswathy V, Gamba-Vitalo, Christina, Vaishnaw, Akshay K, Sah, Dinah W Y, Gollob, Jared A, Burris, 3rd, Howard A
Published in Cancer discovery (01.04.2013)
Published in Cancer discovery (01.04.2013)
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