Design, Synthesis, and Discovery of a Novel CCR1 Antagonist
Naya, Akira, Sagara, Yufu, Ohwaki, Kenji, Saeki, Toshihiko, Ichikawa, Daisuke, Iwasawa, Yoshikazu, Noguchi, Kazuhito, Ohtake, Norikazu
Published in Journal of medicinal chemistry (26.04.2001)
Published in Journal of medicinal chemistry (26.04.2001)
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Structure–Activity Relationships of 2-(Benzothiazolylthio)acetamide Class of CCR3 Selective Antagonist
Naya, Akira, Kobayashi, Kensuke, Ishikawa, Makoto, Ohwaki, Kenji, Saeki, Toshihiko, Noguchi, Kazuhito, Ohtake, Norikazu
Published in Chemical & Pharmaceutical Bulletin (2003)
Published in Chemical & Pharmaceutical Bulletin (2003)
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Discovery of a novel CCR3 selective antagonist
Naya, Akira, Kobayashi, Kensuke, Ishikawa, Makoto, Ohwaki, Kenji, Saeki, Toshihiko, Noguchi, Kazuhito, Ohtake, Norikazu
Published in Bioorganic & medicinal chemistry letters (07.05.2001)
Published in Bioorganic & medicinal chemistry letters (07.05.2001)
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An endothelin receptor (ET A) antagonist isolated from Streptomyces misakiensis
Ihara, Masaki, Fukuroda, Takahiro, Saeki, Toshihiko, Nishikibe, Masaru, Kojiri, Katsuhisa, Suda, Hiroyuki, Yano, Mitsuo
Published in Biochemical and biophysical research communications (15.07.1991)
Published in Biochemical and biophysical research communications (15.07.1991)
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Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala 1,3,11,15]ET-1
Nakamichi, Kyoko, Ihara, Masaki, Kobayashi, Masahiko, Saeki, Toshihiko, Ishikawa, Kiyofumi, Yano, Mitsuo
Published in Biochemical and biophysical research communications (15.01.1992)
Published in Biochemical and biophysical research communications (15.01.1992)
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Supportive therapies for prevention of hepatocellular carcinoma recurrence and preservation of liver function
Takami, Taro, Yamasaki, Takahiro, Saeki, Issei, Matsumoto, Toshihiko, Suehiro, Yutaka, Sakaida, Isao
Published in World journal of gastroenterology : WJG (28.08.2016)
Published in World journal of gastroenterology : WJG (28.08.2016)
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Suppressive effects of the endothelin receptor (ETA) antagonist BQ-123 on ET-1-induced reduction of lipoprotein lipase activity in 3T3-L1 adipocytes
Ishida, F, Saeki, K, Saeki, T, Ishikawa, K, Ihara, M, Kamei, T, Yano, M
Published in Biochemical pharmacology (06.10.1992)
Published in Biochemical pharmacology (06.10.1992)
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Biochemical and Pharmacological Profile of a Potent and Selective Endothelin B-Receptor Antagonist, BQ-788
Ishikawa, Kiyofumi, Ihara, Masaki, Noguchi, Kazuhito, Mase, Toshiaki, Mino, Nobuyuki, Saeki, Toshihiko, Fukuroda, Takahiro, Fukami, Takehiro, Ozaki, Satoshi, Nagase, Toshio, Nishikibe, Masaru, Yano, Mitsuo
Published in Proceedings of the National Academy of Sciences - PNAS (24.05.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (24.05.1994)
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In vitro biological profile of a highly potent novel endothelin (ET) antagonist BQ-123 selective for the ETA receptor
Ihara, M, Ishikawa, K, Fukuroda, T, Saeki, T, Funabashi, K, Fukami, T, Suda, H, Yano, M
Published in Journal of cardiovascular pharmacology (01.04.1992)
Published in Journal of cardiovascular pharmacology (01.04.1992)
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[Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity
SAEKI, T, IHARA, M, FUKURODA, T, YAMAGIWA, M, YANO, M
Published in Biochemical and biophysical research communications (30.08.1991)
Published in Biochemical and biophysical research communications (30.08.1991)
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Endothelin Receptor Subtypes in Porcine Tissues
Ihara, Masaki, Saeki, Toshihiko, Kimura, Sachiyo, Yano, Mitsuo
Published in Japanese Journal of Pharmacology (1990)
Published in Japanese Journal of Pharmacology (1990)
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CHEMOKINE RECEPTOR ANTAGONISTS
NAYA, AKIRA, OHWAKI, KENJI, SAEKI, TOSHIHIKO, IWASAWA, YOSHIKAZU, OWADA, YUFU
Year of Publication 05.02.1998
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Year of Publication 05.02.1998
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A novel radioligand [125I]BQ-3020 selective for endothelin (ETB) receptors
Ihara, M, Saeki, T, Fukuroda, T, Kimura, S, Ozaki, S, Patel, A C, Yano, M
Published in Life sciences (1973) (1992)
Published in Life sciences (1973) (1992)
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NOVEL PIPERIDINE DERIVATIVES
OTAKE, NORIKAZU, NAYA, AKIRA, ISHIKAWA, MAKOTO, KOBAYASHI, KENSUKE, OHWAKI, KENJI, NOGUCHI, KAZUHITO, SAEKI, TOSHIHIKO
Year of Publication 14.09.2000
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Year of Publication 14.09.2000
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VASORELAXANT PEPTIDE
IHARA, MASAKI, FUKURODA, TAKAHIRO, NAKAMICHI, KYOKO, SAEKI, TOSHIHIKO
Year of Publication 12.11.1992
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Year of Publication 12.11.1992
Patent