Targeted DNA and RNA Sequencing of Paired Urothelial and Squamous Bladder Cancers Reveals Discordant Genomic and Transcriptomic Events and Unique Therapeutic Implications
Hovelson, Daniel H., Udager, Aaron M., McDaniel, Andrew S., Grivas, Petros, Palmbos, Phillip, Tamura, Shuzo, Lazo de la Vega, Lorena, Palapattu, Ganesh, Veeneman, Brendan, El-Sawy, Layla, Sadis, Seth E., Morgan, Todd M., Montgomery, Jeffrey S., Weizer, Alon Z., Day, Kathleen C., Neamati, Nouri, Liebert, Monica, Keller, Evan T., Day, Mark L., Mehra, Rohit, Tomlins, Scott A.
Published in European urology (01.12.2018)
Published in European urology (01.12.2018)
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Identification of targetable FGFR gene fusions in diverse cancers
Wu, Yi-Mi, Su, Fengyun, Kalyana-Sundaram, Shanker, Khazanov, Nickolay, Ateeq, Bushra, Cao, Xuhong, Lonigro, Robert J, Vats, Pankaj, Wang, Rui, Lin, Su-Fang, Cheng, Ann-Joy, Kunju, Lakshmi P, Siddiqui, Javed, Tomlins, Scott A, Wyngaard, Peter, Sadis, Seth, Roychowdhury, Sameek, Hussain, Maha H, Feng, Felix Y, Zalupski, Mark M, Talpaz, Moshe, Pienta, Kenneth J, Rhodes, Daniel R, Robinson, Dan R, Chinnaiyan, Arul M
Published in Cancer discovery (01.06.2013)
Published in Cancer discovery (01.06.2013)
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Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors
Hovelson, Daniel H, McDaniel, Andrew S, Cani, Andi K, Johnson, Bryan, Rhodes, Kate, Williams, Paul D, Bandla, Santhoshi, Bien, Geoffrey, Choppa, Paul, Hyland, Fiona, Gottimukkala, Rajesh, Liu, Guoying, Manivannan, Manimozhi, Schageman, Jeoffrey, Ballesteros-Villagrana, Efren, Grasso, Catherine S, Quist, Michael J, Yadati, Venkata, Amin, Anmol, Siddiqui, Javed, Betz, Bryan L, Knudsen, Karen E, Cooney, Kathleen A, Feng, Felix Y, Roh, Michael H, Nelson, Peter S, Liu, Chia-Jen, Beer, David G, Wyngaard, Peter, Chinnaiyan, Arul M, Sadis, Seth, Rhodes, Daniel R, Tomlins, Scott A
Published in Neoplasia (New York, N.Y.) (01.04.2015)
Published in Neoplasia (New York, N.Y.) (01.04.2015)
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Next-Gen Sequencing Exposes Frequent MED12 Mutations and Actionable Therapeutic Targets in Phyllodes Tumors
Cani, Andi K, Hovelson, Daniel H, McDaniel, Andrew S, Sadis, Seth, Haller, Michaela J, Yadati, Venkata, Amin, Anmol M, Bratley, Jarred, Bandla, Santhoshi, Williams, Paul D, Rhodes, Kate, Liu, Chia-Jen, Quist, Michael J, Rhodes, Daniel R, Grasso, Catherine S, Kleer, Celina G, Tomlins, Scott A
Published in Molecular cancer research (01.04.2015)
Published in Molecular cancer research (01.04.2015)
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Monoclonal antibodies against macrophage colony-stimulating factor diminish the number of circulating intermediate and nonclassical (CD14++CD16+/CD14+CD16++) monocytes in rheumatoid arthritis patient
Korkosz, Mariusz, Bukowska-Strakova, Karolina, Sadis, Seth, Grodzicki, Tomasz, Siedlar, Maciej
Published in Blood (31.05.2012)
Published in Blood (31.05.2012)
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Multisite verification of the accuracy of a multi-gene next generation sequencing panel for detection of mutations and copy number alterations in solid tumours
Bartlett, John, Amemiya, Yutaka, Arts, Heleen, Bayani, Jane, Eng, Barry, Grafodatskaya, Daria, Kamel Reid, Suzanne, Lariviere, Mathieu, Lo, Bryan, McClure, Rebecca, Mittal, Vinay, Sadikovic, Bekim, Sadis, Seth, Seth, Arun, Smith, Jeff, Zhang, Xiao, Feilotter, Harriet
Published in PloS one (01.10.2021)
Published in PloS one (01.10.2021)
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A scalable solution for tumor mutational burden from formalin-fixed, paraffin-embedded samples using the Oncomine Tumor Mutation Load Assay
Chaudhary, Ruchi, Quagliata, Luca, Martin, Jermann Philip, Alborelli, Ilaria, Cyanam, Dinesh, Mittal, Vinay, Tom, Warren, Au-Young, Janice, Sadis, Seth, Hyland, Fiona
Published in Translational lung cancer research (01.12.2018)
Published in Translational lung cancer research (01.12.2018)
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Journal Article
Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity
Marzec, Michal, Kasprzycka, Monika, Lai, Raymond, Gladden, Andrew B., Wlodarski, Pawel, Tomczak, Ewa, Nowell, Peter, DePrimo, Samuel E., Sadis, Seth, Eck, Stephen, Schuster, Stephen J., Diehl, J. Alan, Wasik, Mariusz A.
Published in Blood (01.09.2006)
Published in Blood (01.09.2006)
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Journal Article
Complementary Whole-Genome Technologies Reveal the Cellular Response to Proteasome Inhibition by PS-341
Fleming, James A., Lightcap, Eric S., Sadis, Seth, Thoroddsen, Vala, Bulawa, Christine E., Blackman, Ronald K.
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2002)
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Journal Article
The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover
Nocker, Steven van, Sadis, Seth, Rubin, David M., Glickman, Michael, Fu, Hongyong, Coux, Olivier, Wefes, Inge, Finley, Daniel, Vierstra, Richard D.
Published in Molecular and Cellular Biology (01.11.1996)
Published in Molecular and Cellular Biology (01.11.1996)
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Multiubiquitin Chain Binding and Protein Degradation Are Mediated by Distinct Domains within the 26 S Proteasome Subunit Mcb1
Fu, Hongyong, Sadis, Seth, Rubin, David M., Glickman, Michael, van Nocker, Steven, Finley, Daniel, Vierstra, Richard D.
Published in The Journal of biological chemistry (23.01.1998)
Published in The Journal of biological chemistry (23.01.1998)
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Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs
Fleischmann, Roy, Cutolo, Maurizio, Genovese, Mark C., Lee, Eun Bong, Kanik, Keith S., Sadis, Seth, Connell, Carol A., Gruben, David, Krishnaswami, Sriram, Wallenstein, Gene, Wilkinson, Bethanie E., Zwillich, Samuel H.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2012)
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Detection of KMT2A Partial Tandem Duplications ( KMT2A-PTDs) in Healthy Donors Using Next Generation Sequencing
Huang, Jiajie, Gu, Haigang, Orton, Janet, Sedova, Marina, Marcovitz, Amir, Burke, Jennifer, Brozio, Sarah, Williams, Paul, Myrand, Scott, Olowo, Nate, Broomer, Adam, Deal, Brendan, Seeger, Collyn, Sadis, Seth, Rozenzhak, Sophie, Hyland, Fiona, Liu, Guang
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Abstract 3492: A targeted semi-conductor based next-generation sequencing (NGS) test to characterize microsatellite instability in FFPE tumor samples
Kraltcheva, Anelia, El-Difrawy, Sameh, Kamat, Asha, Au-Young, Janice, Cawley, Simon, Sadis, Seth
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Abstract 5472: Development of customizable targeted RNA fusion panels using a novel automated high-multiplexing primer design strategy
LI, NA, Martinez-Alcantara, Antonio, Ewing, Aren, Gottimukkala, Rajesh, Hyland, Fiona, Sadis, Seth
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Monoclonal antibodies against macrophage colony-stimulating factor diminish the number of circulating intermediate and nonclassical (CD14(++)CD16(+)/CD14(+)CD16(++)) monocytes in rheumatoid arthritis patient
Korkosz, Mariusz, Bukowska-Strakova, Karolina, Sadis, Seth, Grodzicki, Tomasz, Siedlar, Maciej
Published in Blood (31.05.2012)
Published in Blood (31.05.2012)
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Journal Article
Genomic Profiling of Penile Squamous Cell Carcinoma Reveals New Opportunities for Targeted Therapy
McDaniel, Andrew S, Hovelson, Daniel H, Cani, Andi K, Liu, Chia-Jen, Zhai, Yali, Zhang, Yajia, Weizer, Alon Z, Mehra, Rohit, Feng, Felix Y, Alva, Ajjai S, Morgan, Todd M, Montgomery, Jeffrey S, Siddiqui, Javed, Sadis, Seth, Bandla, Santhoshi, Williams, Paul D, Cho, Kathleen R, Rhodes, Daniel R, Tomlins, Scott A
Published in Cancer research (Chicago, Ill.) (15.12.2015)
Published in Cancer research (Chicago, Ill.) (15.12.2015)
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Abstract 580: A method for estimating mutation load from tumor research samples using a targeted next-generation sequencing panel
Chaudhary, Ruchi, Cyanam, Dinesh, Mittal, Vinay, Tom, Warren, Au-Young, Janice, Sadis, Seth, Hyland, Fiona
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 5132: Assessing tumor mutational burden and profiling variants from FFPE samples using a PCR-based next-generation sequencing assay
Chaudhary, Ruchi, Scafe, Charles, Cyanam, Dinesh, Mittal, Vinay, Tom, Warren, Au-Young, Janice, Sadis, Seth, Hyland, Fiona
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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