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Transcription Factor Activities Enhance Markers of Drug Sensitivity in Cancer
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Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability
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TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells
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Published in Cell death & disease (23.09.2021)
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Dissecting the DNA binding landscape and gene regulatory network of p63 and p53
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Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification
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Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil
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Published in Nucleic acids research (01.10.2024)
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Sessler, Tamas, Quinn, Gerard P., Wappett, Mark, Rogan, Emily, Sharkey, David, Ahmaderaghi, Baharak, Lawler, Mark, Longley, Daniel B., McDade, Simon S.
Published in Scientific reports (13.12.2023)
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classifieR a flexible interactive cloud-application for functional annotation of cancer transcriptomes
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BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability
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Evidence for Alteration of EZH2, BMI1, and KDM6A and Epigenetic Reprogramming in Human Papillomavirus Type 16 E6/E7-Expressing Keratinocytes
HYLAND, Paula L, MCDADE, Simon S, MCCLOSKEY, Rachel, DICKSON, Glenda J, ARTHUR, Ken, MCCANCE, Dennis J, PATEL, Daksha
Published in Journal of Virology (01.11.2011)
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Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML
Smith, James S, Lappin, Katrina M, Craig, Stephanie G, Liberante, Fabio G, Crean, Clare M, McDade, Simon S, Thompson, Alexander, Mills, Ken I, Savage, Kienan I
Published in Journal of translational medicine (03.09.2020)
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Comparison of Molecular Assays for HPV Testing in Oropharyngeal Squamous Cell Carcinomas: A Population-Based Study in Northern Ireland
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Published in Cancer epidemiology, biomarkers & prevention (01.01.2020)
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Autocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells
Steiner, Ivana, Flores-Tellez, Teresita del N.J., Mevel, Renaud, Ali, Amin, Wang, Pengbo, Schofield, Pieta, Behan, Caron, Forsythe, Nicholas, Ashton, Garry, Taylor, Catherine, Mills, Ian G., Oliveira, Pedro, McDade, Simon S., Zaiss, Dietmar M., Choudhury, Ananya, Lacaud, Georges, Baena, Esther
Published in Cell reports (Cambridge) (25.04.2023)
Published in Cell reports (Cambridge) (25.04.2023)
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MicroRNA 203 Expression in Keratinocytes Is Dependent on Regulation of p53 Levels by E6
MCKENNA, Declan J, MCDADE, Simon S, PATEL, Daksha, MCCANCE, Dennis J
Published in Journal of Virology (01.10.2010)
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Investigating Radiotherapy Response in a Novel Syngeneic Model of Prostate Cancer
Haughey, Charles M, Mukherjee, Debayan, Steele, Rebecca E, Popple, Amy, Dura-Perez, Lara, Pickard, Adam, Patel, Mehjabin, Jain, Suneil, Mullan, Paul B, Williams, Rich, Oliveira, Pedro, Buckley, Niamh E, Honeychurch, Jamie, S McDade, Simon, Illidge, Timothy, Mills, Ian G, Eddie, Sharon L
Published in Cancers (29.09.2020)
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A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence
Brien, Gerard L, Healy, Evan, Jerman, Emilia, Conway, Eric, Fadda, Elisa, O'Donovan, Darragh, Krivtsov, Andrei V, Rice, Alan M, Kearney, Conor J, Flaus, Andrew, McDade, Simon S, Martin, Seamus J, McLysaght, Aoife, O'Connell, David J, Armstrong, Scott A, Bracken, Adrian P
Published in Genes & development (01.11.2015)
Published in Genes & development (01.11.2015)
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Molecular Subtyping Resource: a user-friendly tool for rapid biological discovery from transcriptional data
Ahmaderaghi, Baharak, Amirkhah, Raheleh, Jackson, James, Lannagan, Tamsin R M, Gilroy, Kathryn, Malla, Sudhir B, Redmond, Keara L, Quinn, Gerard, McDade, Simon S, ACRCelerate Consortium, Maughan, Tim, Leedham, Simon, Campbell, Andrew S D, Sansom, Owen J, Lawler, Mark, Dunne, Philip D
Published in Disease models & mechanisms (01.03.2022)
Published in Disease models & mechanisms (01.03.2022)
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HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures
Pickard, Adam, McDade, Simon S, McFarland, Marie, McCluggage, W Glenn, Wheeler, Cosette M, McCance, Dennis J
Published in PLoS pathogens (01.06.2015)
Published in PLoS pathogens (01.06.2015)
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