The tyrosine kinase inhibitors imatinib and dasatinib reduce myeloid suppressor cells and release effector lymphocyte responses
Christiansson, Lisa, Söderlund, Stina, Mangsbo, Sara, Hjorth-Hansen, Henrik, Höglund, Martin, Markevärn, Berit, Richter, Johan, Stenke, Leif, Mustjoki, Satu, Loskog, Angelica, Olsson-Strömberg, Ulla
Published in Molecular cancer therapeutics (01.05.2015)
Published in Molecular cancer therapeutics (01.05.2015)
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Molecular status 36 months after TKI discontinuation in CML is highly predictive for subsequent loss of MMR-final report from AFTER-SKI
Richter, Johan, Lübking, Anna, Söderlund, Stina, Lotfi, Kourosh, Markevärn, Berit, Själander, Anders, Stenke, Leif, Deneberg, Stefan, Ahlstrand, Erik, Myhr-Eriksson, Kristina, Panayiotidis, Panayiotis, Gedde-Dahl, Tobias, Žáčková, Daniela, Mayer, Jiří, Olsson-Strömberg, Ulla, Mahon, Francois-Xavier, Saussele, Susanne, Hjorth-Hansen, Henrik, Koskenvesa, Perttu
Published in Leukemia (01.08.2021)
Published in Leukemia (01.08.2021)
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Musculoskeletal pain in patients with chronic myeloid leukemia after discontinuation of imatinib: a tyrosine kinase inhibitor withdrawal syndrome?
Richter, Johan, Söderlund, Stina, Lübking, Anna, Dreimane, Arta, Lotfi, Kourosh, Markevärn, Berit, Själander, Anders, Saussele, Susanne, Olsson-Strömberg, Ulla, Stenke, Leif
Published in Journal of clinical oncology (01.09.2014)
Published in Journal of clinical oncology (01.09.2014)
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Proteomic and transcriptomic screening demonstrates increased mast cell–derived CCL23 in systemic mastocytosis
Söderlund, Stina, Boey, Daryl, van Midden, Wouter, Kjellander, Matilda, Ax, Kajsa, Qian, Hong, Dahlin, Joakim S., Ungerstedt, Johanna
Published in Journal of allergy and clinical immunology (01.07.2023)
Published in Journal of allergy and clinical immunology (01.07.2023)
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Plasma Proteomics in CML patients before and after initiation of tyrosine kinase inhibitor therapy reveals induced Th1 immunity and loss of angiogenic stimuli
Söderlund, Stina, MD, Christiansson, Lisa, Persson, Inger, Hjorth-Hansen, Henrik, Richter, Johan, Simonsson, Bengt, Mustjoki, Satu, Olsson-Strömberg, Ulla, Loskog, Angelica
Published in Leukemia research (01.11.2016)
Published in Leukemia research (01.11.2016)
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IFN-[alpha] with dasatinib broadens the immune repertoire in patients with chronic-phase chronic myeloid leukemia
Huuhtanen, Jani, Ilander, Mette, Yadav, Bhagwan, Dufva, Olli M.J, Lahteenmaki, Hanna, Kasanen, Tiina, Klievink, Jay, Olsson-Stromberg, Ulla, Stentoft, Jesper, Richter, Johan, Koskenvesa, Perttu, Hoglund, Martin, Soderlund, Stina, Dreimane, Arta, Porkka, Kimmo, Gedde-Dahl, Tobias, Gjertsen, Bjorn T, Stenke, Leif, Myhr-Eriksson, Kristina, Markevarn, Berit, Lubking, Anna, Dimitrijevic, Andreja, Udby, Lene, Bjerrum, Ole Weis, Hjorth-Hansen, Henrik, Mustjoki, Satu
Published in The Journal of clinical investigation (01.09.2022)
Published in The Journal of clinical investigation (01.09.2022)
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Successful tyrosine kinase inhibitor discontinuation outside clinical trials — data from the population‐based Swedish chronic myeloid leukaemia registry
Flygt, Hjalmar, Sandin, Fredrik, Dahlén, Torsten, Dremaine, Arta, Lübking, Anna, Markevärn, Berit, Myhr‐Eriksson, Kristina, Olsson, Karin, Olsson‐Strömberg, Ulla, Själander, Anders, Söderlund, Stina, Wennström, Lovisa, Wadenvik, Hans, Stenke, Leif, Höglund, Martin, Richter, Johan
Published in British journal of haematology (01.06.2021)
Published in British journal of haematology (01.06.2021)
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IFN-α with dasatinib broadens the immune repertoire in patients with chronic-phase chronic myeloid leukemia
Huuhtanen, Jani, Ilander, Mette, Yadav, Bhagwan, Dufva, Olli M.J., Lähteenmäki, Hanna, Kasanen, Tiina, Klievink, Jay, Olsson-Strömberg, Ulla, Stentoft, Jesper, Richter, Johan, Koskenvesa, Perttu, Höglund, Martin, Söderlund, Stina, Dreimane, Arta, Porkka, Kimmo, Gedde-Dahl, Tobias, Gjertsen, Björn T., Stenke, Leif, Myhr-Eriksson, Kristina, Markevärn, Berit, Lübking, Anna, Dimitrijevic, Andreja, Udby, Lene, Bjerrum, Ole Weis, Hjorth-Hansen, Henrik, Mustjoki, Satu
Published in The Journal of clinical investigation (01.09.2022)
Published in The Journal of clinical investigation (01.09.2022)
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Immunological monitoring of newly diagnosed CML patients treated with bosutinib or imatinib first-line
Kreutzman, Anna, Yadav, Bhagwan, Brummendorf, Tim H., Gjertsen, Bjorn Tore, Hee Lee, Moon, Janssen, Jeroen, Kasanen, Tiina, Koskenvesa, Perttu, Lotfi, Kourosh, Markevärn, Berit, Olsson-Strömberg, Ulla, Stentoft, Jesper, Stenke, Leif, Söderlund, Stina, Udby, Lene, Richter, Johan, Hjorth-Hansen, Henrik, Mustjoki, Satu
Published in Oncoimmunology (2019)
Published in Oncoimmunology (2019)
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Increased level of myeloid-derived suppressor cells, programmed death receptor ligand 1/programmed death receptor 1, and soluble CD25 in Sokal high risk chronic myeloid leukemia
Christiansson, Lisa, Söderlund, Stina, Svensson, Emma, Mustjoki, Satu, Bengtsson, Mats, Simonsson, Bengt, Olsson-Strömberg, Ulla, Loskog, Angelica S I
Published in PloS one (31.01.2013)
Published in PloS one (31.01.2013)
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Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: clinical results from a randomised phase-2 study (NordCML006)
Hjorth-Hansen, Henrik, Stenke, Leif, Söderlund, Stina, Dreimane, Arta, Ehrencrona, Hans, Gedde-Dahl, Tobias, Gjertsen, Bjørn Tore, Höglund, Martin, Koskenvesa, Perttu, Lotfi, Kourosh, Majeed, Waleed, Markevärn, Berit, Ohm, Lotta, Olsson-Strömberg, Ulla, Remes, Kari, Suominen, Merja, Simonsson, Bengt, Porkka, Kimmo, Mustjoki, Satu, Richter, Johan
Published in European journal of haematology (01.03.2015)
Published in European journal of haematology (01.03.2015)
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Long‐term tolerability and efficacy after initial PegIFN‐α addition to dasatinib in CML‐CP: Five‐year follow‐up of the NordCML007 study
Flygt, Hjalmar, Söderlund, Stina, Stentoft, Jesper, Richter, Johan, Koskenvesa, Perttu, Mustjoki, Satu, Majeed, Waleed, Lübking, Anna, Dreimane, Arta, Markevärn, Berit, Stenke, Leif, Myhr Eriksson, Kristina, Gjertsen, Bjørn Tore, Gedde‐Dahl, Tobias, Dimitrijevic, Andreja, Udby, Lene, Olsson‐Strömberg, Ulla, Hjorth‐Hansen, Henrik
Published in European journal of haematology (01.12.2021)
Published in European journal of haematology (01.12.2021)
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Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis
Grootens, Jennine, Ungerstedt, Johanna S., Ekoff, Maria, Rönnberg, Elin, Klimkowska, Monika, Amini, Rose-Marie, Arock, Michel, Söderlund, Stina, Mattsson, Mattias, Nilsson, Gunnar, Dahlin, Joakim S.
Published in EBioMedicine (01.05.2019)
Published in EBioMedicine (01.05.2019)
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Intestinal flora in very low-birth weight infants
Björkström, Markus V., Hall, Lina, Söderlund, Stina, Håkansson, Eva Grahn, Håkansson, Stellan, Domellöf, Magnus
Published in Acta Paediatrica (01.11.2009)
Published in Acta Paediatrica (01.11.2009)
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Advanced phase chronic myeloid leukaemia (CML) in the tyrosine kinase inhibitor era – a report from the Swedish CML register
Söderlund, Stina, Dahlén, Torsten, Sandin, Fredrik, Olsson‐Strömberg, Ulla, Creignou, Maria, Dreimane, Arta, Lübking, Anna, Markevärn, Berit, Själander, Anders, Wadenvik, Hans, Stenke, Leif, Richter, Johan, Höglund, Martin
Published in European journal of haematology (01.01.2017)
Published in European journal of haematology (01.01.2017)
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In Vivo Cytochrome P450 3A Isoenzyme Activity and Pharmacokinetics of Imatinib in Relation to Therapeutic Outcome in Patients With Chronic Myeloid Leukemia
Skoglund, Karin, Richter, Johan, Olsson-Strömberg, Ulla, Bergquist, Jonas, Aluthgedara, Warunika, Ubhayasekera, S J Kumari A, Vikingsson, Svante, Svedberg, Anna, Söderlund, Stina, Sandstedt, Anna, Johnsson, Anders, Aagesen, Jesper, Alsenhed, Jonas, Hägg, Staffan, Peterson, Curt, Lotfi, Kourosh, Gréen, Henrik
Published in Therapeutic drug monitoring (01.04.2016)
Published in Therapeutic drug monitoring (01.04.2016)
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Increased Levels of Myeloid-Derived Suppressor Cells (MDSCs) in Chronic Myeloid Leukemia and the Effect of Tyrosine Kinase Inhibitors on MDSCs in Vitro
Christiansson, Lisa H, Söderlund, Stina, Svensson, Emma, Bengtsson, Mats, Simonsson, Bengt, Olsson-Strömberg, Ulla, Loskog, Angelica
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Disease Relapse After TKI Discontinuation In CML Is Related Both To Low Number and Impaired Function Of NK-Cells:Data From Euro-SKI
Ilander, Mette Matilda, Olsson-Strömberg, Ulla, Lähteenmäki, Hanna, Kasanen, Tiina, Koskenvesa, Perttu, Söderlund, Stina, Hoglund, Martin, Markevärn, Berit, Själander, Anders, Lofti, Kourosh, Malm, Claes, Lubking, Anna, Ekblom, Marja, Holm, Elena, Björeman, Mats, Lehmann, Sören, Stenke, Leif, Ohm, Lotta, Hjorth-Hansen, Henrik, Saussele, Susanne, Mahon, Francois-Xavier, Porkka, Kimmo, Richter, Johan, Mustjoki, Satu
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Disease Relapse After Tyrosine Kinase Inhibitor Treatment Discontinuation in Chronic Myeloid Leukaemia is Related to Both Low Number and Impaired Function of NK Cells
Ilander, Mette, Olsson-Stromberg, Ulla, Lahteenmaki, Hanna, Kasanen, Tiina, Koskenvesa, Perttu, Soderlund, Stina, Hoglund, Martin, Markevärn, Berit, Själander, Anders, Lofti, Kouros, Malm, Claes, Lubking, Anna, Ekblom, Marja, Holm, Elena, Bjoreman, Mats, Lehmann, Soren, Stenke, Leif, Ohm, Lotta, Hjorth-Hansen, Henrik, Saussele, Susanne, Mahon, Francois-Xavier, Porkka, Kimmo, Richter, Johan, Mustjoki, Satu
Published in Scandinavian journal of immunology (2014)
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Published in Scandinavian journal of immunology (2014)
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Discontinuation of tyrosine kinase inhibitor therapy in chronic myeloid leukaemia (EURO-SKI): a prespecified interim analysis of a prospective, multicentre, non-randomised, trial
Saussele, Susanne, Richter, Johan, Guilhot, Joelle, Gruber, Franz X, Hjorth-Hansen, Henrik, Almeida, Antonio, Janssen, Jeroen J W M, Mayer, Jiri, Koskenvesa, Perttu, Panayiotidis, Panayiotis, Olsson-Strömberg, Ulla, Martinez-Lopez, Joaquin, Rousselot, Philippe, Vestergaard, Hanne, Ehrencrona, Hans, Kairisto, Veli, Machová Poláková, Katerina, Müller, Martin C, Mustjoki, Satu, Berger, Marc G, Fabarius, Alice, Hofmann, Wolf-Karsten, Hochhaus, Andreas, Pfirrmann, Markus, Mahon, Francois-Xavier, Ossenkoppele, Gert, Pagoni, Maria N., Söderlund, Stina, Escoffre-Barbe, Martine, Etienne, Gabriel, Dengler, Jolanta, Huguet, Francoise, von Bubnoff, Nikolas, Klamova, Hana, Faber, Edgar, Guilhot, Francois, Lotfi, Kourosh, Rea, Delphine, Brümmendorf, Tim H., de Greef, Gorgine E., Stenke, Leif, Nicolini, Franck E., Legros, Laurence, Burchert, Andreas, Voglova, Jaroslava, Charbonnier, Aude, Gyan, Emmanuel, Kunzmann, Volker, Westerweel, Peter E.
Published in The lancet oncology (01.06.2018)
Published in The lancet oncology (01.06.2018)
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