Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription
Duplan, Eric, Sevalle, Jean, Viotti, Julien, Goiran, Thomas, Bauer, Charlotte, Renbaum, Paul, Levy-Lahad, Ephrat, Gautier, Clément A, Corti, Olga, Leroudier, Nathalie, Checler, Frédéric, da Costa, Cristine Alves
Published in Journal of molecular cell biology (01.04.2013)
Published in Journal of molecular cell biology (01.04.2013)
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TREM 2 shedding by cleavage at the H157‐S158 bond is accelerated for the Alzheimer's disease‐associated H157Y variant
Thornton, Peter, Sevalle, Jean, Deery, Michael J, Fraser, Graham, Zhou, Ye, Ståhl, Sara, Franssen, Elske H, Dodd, Roger B, Qamar, Seema, Gomez Perez‐Nievas, Beatriz, Nicol, Louise SC, Eketjäll, Susanna, Revell, Jefferson, Jones, Clare, Billinton, Andrew, St George‐Hyslop, Peter H, Chessell, Iain, Crowther, Damian C
Published in EMBO molecular medicine (01.10.2017)
Published in EMBO molecular medicine (01.10.2017)
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Journal Article
Further characterization of a putative serine protease contributing to the [gamma]-secretase cleavage of [beta]-amyloid precursor protein
Peuchmaur, Marine, Lacour, Marie-Agnes, Sevalle, Jean, Lisowski, Vincent, Touati-Jallabe, Youness, Rodier, Fabien, Martinez, Jean, Checler, Frederic, Hernandez, Jean-Francois
Published in Bioorganic & medicinal chemistry (15.02.2013)
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Published in Bioorganic & medicinal chemistry (15.02.2013)
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Further characterization of a putative serine protease contributing to the I3-secretase cleavage of I2-amyloid precursor protein
Peuchmaur, Marine, Lacour, Marie-AgnA"s, Sevalle, Jean, Lisowski, Vincent, Touati-Jallabe, Youness, Rodier, Fabien, Martinez, Jean, Checler, Frederic, Hernandez, Jean-Francois
Published in Bioorganic & medicinal chemistry (01.02.2013)
Published in Bioorganic & medicinal chemistry (01.02.2013)
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Journal Article
NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42
Buggia-Prevot, Virginie, Sevalle, Jean, Rossner, Steffen, Checler, Frédéric
Published in The Journal of biological chemistry (11.04.2008)
Published in The Journal of biological chemistry (11.04.2008)
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Journal Article
p53-dependent Aph-1 and Pen-2 Anti-apoptotic Phenotype Requires the Integrity of the γ-Secretase Complex but Is Independent of Its Activity
Dunys, Julie, Kawarai, Toshitaka, Sevalle, Jean, Dolcini, Virginia, George-Hyslop, Peter St, Da Costa, Cristine Alves, Checler, Frédéric
Published in The Journal of biological chemistry (06.04.2007)
Published in The Journal of biological chemistry (06.04.2007)
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Journal Article
NFκB-dependent Control of BACE1 Promoter Transactivation by Aβ42
Virginie Buggia-Prevot, Jean Sevalle, Steffen Rossner, Frédéric Checler
Published in The Journal of biological chemistry (11.04.2008)
Published in The Journal of biological chemistry (11.04.2008)
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Journal Article
TMP21 regulates Abeta production but does not affect caspase-3, p53, and neprilysin
Dolcini, Virginia, Dunys, Julie, Sevalle, Jean, Chen, Fusheng, Guillot-Sestier, Marie-Victoire, St George-Hyslop, Peter, Fraser, Paul E, Checler, Frédéric
Published in Biochemical and biophysical research communications (20.06.2008)
Published in Biochemical and biophysical research communications (20.06.2008)
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Journal Article
TMP21 regulates Aβ production but does not affect caspase-3, p53, and neprilysin
Dolcini, Virginia, Dunys, Julie, Sevalle, Jean, Chen, Fusheng, Guillot-Sestier, Marie-Victoire, St. George-Hyslop, Peter, Fraser, Paul E., Checler, Frédéric
Published in Biochemical and biophysical research communications (20.06.2008)
Published in Biochemical and biophysical research communications (20.06.2008)
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Journal Article
p53-dependent Aph-1 and Pen-2 Anti-apoptotic Phenotype Requires the Integrity of the γ-Secretase Complex but Is Independent of Its Activity
Julie Dunys, Toshitaka Kawarai, Jean Sevalle, Virginia Dolcini, Peter St. George-Hyslop, Cristine Alves Da Costa, Frédéric Checler
Published in The Journal of biological chemistry (06.04.2007)
Published in The Journal of biological chemistry (06.04.2007)
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Journal Article
Presenilin-Dependent {gamma}-Secretase-Mediated Control of p53-Associated Cell Death in Alzheimer's Disease
Alves da Costa, Cristine, Sunyach, Claire, Pardossi-Piquard, Raphaelle, Sevalle, Jean, Vincent, Bruno, Boyer, Nicole, Kawarai, Toshitaka, Girardot, Nadege, St. George-Hyslop, Peter, Checler, Frederic
Published in The Journal of neuroscience (07.06.2006)
Published in The Journal of neuroscience (07.06.2006)
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Journal Article
P3-225: Role of presenilin-dependent gamma-secretase activity in the control of P53-mediated cell death in Alzheimer’s disease
Alves da Costa, Cristine, Sunyach, Claire, Pardossi-Piquard, Raphaelle, Vincent, Bruno, Sevalle, Jean, Kawarai, Toshitaka, St. George-Hyslop, Peter, Shen, Jie, Checler, Frédéric
Published in Alzheimer's & dementia (01.07.2006)
Published in Alzheimer's & dementia (01.07.2006)
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Journal Article
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, while the Alzheimer’s R47H mutant does the opposite
Vilalta, Anna, Zhou, Ye, Sevalle, Jean, Griffin, Jennifer K, Satoh, Kanayo, Allendorf, David H, De, Suman, Mar Puigdellívol, Bruzas, Arturas, Burguillos, Miguel A, Dodd, Roger B, Chen, Fusheng, Zhang, Yalun, Flagmeier, Patrick, Lisa-Maria Needham, Enomoto, Masahiro, Qamar, Seema, Henderson, James, Walter, Jochen, Fraser, Paul E, Klenerman, David, Lee, Steven F, Peter St George-Hyslop, Brown, Guy C
Published in bioRxiv (04.12.2020)
Published in bioRxiv (04.12.2020)
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Paper
Galanthamine derivatives, methods for their obtaining and use
DANALEV, DANCHO LUBENOV, VEZENKOV, LUBOMIR TODOROV, GEORGIEVA, MARIYA GEORGIEVA, MITEV, VANYO IVANOV, HRISTOV, KRUM KRUMOV, IVANOV, CHAVDAR BORISOV, SEVALLE, JEAN, CHECLER, FREDERIC, BAKALOVA, ANASTASSIA TODOROVA
Year of Publication 31.10.2011
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Year of Publication 31.10.2011
Patent
Galanthamine derivatives, methods for their obtaining and use
CHECLER FREDERIC, SEVALLE JEAN, MITEV VANYO IVANOV, GEORGIEVA MARIYA GEORGIEVA, BAKALOVA ANASTASSIA TODOROVA, HRISTOV KRUM KRUMOV, DANALEV DANCHO LUBENOV, IVANOV CHAVDAR BORISOV, VEZENKOV LUBOMIR TODOROV
Year of Publication 31.08.2011
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Year of Publication 31.08.2011
Patent