A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition
Benslimane, Yahya, Sánchez‐Osuna, María, Coulombe‐Huntington, Jasmin, Bertomeu, Thierry, Henry, Danielle, Huard, Caroline, Bonneil, Éric, Thibault, Pierre, Tyers, Mike, Harrington, Lea
Published in Aging cell (01.04.2021)
Published in Aging cell (01.04.2021)
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PRMT5 inhibition disrupts splicing and stemness in glioblastoma
Sachamitr, Patty, Ho, Jolene C, Ciamponi, Felipe E, Ba-Alawi, Wail, Coutinho, Fiona J, Guilhamon, Paul, Kushida, Michelle M, Cavalli, Florence M G, Lee, Lilian, Rastegar, Naghmeh, Vu, Victoria, Sánchez-Osuna, María, Coulombe-Huntington, Jasmin, Kanshin, Evgeny, Whetstone, Heather, Durand, Mathieu, Thibault, Philippe, Hart, Kirsten, Mangos, Maria, Veyhl, Joseph, Chen, Wenjun, Tran, Nhat, Duong, Bang-Chi, Aman, Ahmed M, Che, Xinghui, Lan, Xiaoyang, Whitley, Owen, Zaslaver, Olga, Barsyte-Lovejoy, Dalia, Richards, Laura M, Restall, Ian, Caudy, Amy, Röst, Hannes L, Bonday, Zahid Quyoom, Bernstein, Mark, Das, Sunit, Cusimano, Michael D, Spears, Julian, Bader, Gary D, Pugh, Trevor J, Tyers, Mike, Lupien, Mathieu, Haibe-Kains, Benjamin, Artee Luchman, H, Weiss, Samuel, Massirer, Katlin B, Prinos, Panagiotis, Arrowsmith, Cheryl H, Dirks, Peter B
Published in Nature communications (12.02.2021)
Published in Nature communications (12.02.2021)
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Chemical Genetics Screen Identifies COPB2 Tool Compounds That Alters ER Stress Response and Induces RTK Dysregulation in Lung Cancer Cells
Saraon, Punit, Snider, Jamie, Schormann, Wiebke, Rai, Ankit, Radulovich, Nikolina, Sánchez-Osuna, Maria, Coulombe-Huntington, Jasmin, Huard, Caroline, Mohammed, Mohammed, Lima-Fernandes, Evelyne, Thériault, Brigitte, Halabelian, Levon, Chan, Manuel, Joshi, Dhananjay, Drecun, Luka, Yao, Zhong, Pathmanathan, Shivanthy, Wong, Victoria, Lyakisheva, Anna, Aboualizadeh, Farzaneh, Niu, Li, Li, Fengling, Kiyota, Taira, Subramanian, Ratheesh, Joseph, Babu, Aman, Ahmed, Prakesch, Michael, Isaac, Methvin, Mamai, Ahmed, Poda, Gennady, Vedadi, Masoud, Marcellus, Richard, Uehling, David, Leighl, Natasha, Sacher, Adrian, Samaržija, Miroslav, Jakopović, Marko, Arrowsmith, Cheryl, Tyers, Mike, Tsao, Ming-Sound, Andrews, David, Al-awar, Rima, Stagljar, Igor
Published in Journal of molecular biology (19.11.2021)
Published in Journal of molecular biology (19.11.2021)
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Chromatin Collapse during Caspase-dependent Apoptotic Cell Death Requires DNA Fragmentation Factor, 40-kDa Subunit-/Caspase-activated Deoxyribonuclease-mediated 3′-OH Single-strand DNA Breaks
Iglesias-Guimarais, Victoria, Gil-Guiñon, Estel, Sánchez-Osuna, María, Casanelles, Elisenda, García-Belinchón, Mercè, Comella, Joan X., Yuste, Victor J.
Published in The Journal of biological chemistry (29.03.2013)
Published in The Journal of biological chemistry (29.03.2013)
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Gossypol Treatment Restores Insufficient Apoptotic Function of DFF40/CAD in Human Glioblastoma Cells
Martínez-Escardó, Laura, Alemany, Montse, Sánchez-Osuna, María, Sánchez-Chardi, Alejandro, Roig-Martínez, Meritxell, Suárez-García, Salvio, Ruiz-Molina, Daniel, Vidal, Noemi, Plans, Gerard, Majós, Carles, Ribas, Judit, Baltrons, María Antonia, Bayascas, Jose R., Barcia, Carlos, Bruna, Jordi, Yuste, Victor J.
Published in Cancers (08.11.2021)
Published in Cancers (08.11.2021)
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Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells
Benslimane, Yahya, Bertomeu, Thierry, Coulombe-Huntington, Jasmin, McQuaid, Mary, Sánchez-Osuna, María, Papadopoli, David, Avizonis, Daina, Russo, Mariana De Sa Tavares, Huard, Caroline, Topisirovic, Ivan, Wurtele, Hugo, Tyers, Mike, Harrington, Lea
Published in Molecular cell (03.09.2020)
Published in Molecular cell (03.09.2020)
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Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response
Szewczyk, Magdalena M, Ishikawa, Yoshinori, Organ, Shawna, Sakai, Nozomu, Li, Fengling, Halabelian, Levon, Ackloo, Suzanne, Couzens, Amber L, Eram, Mohammad, Dilworth, David, Fukushi, Hideto, Harding, Rachel, Dela Seña, Carlo C, Sugo, Tsukasa, Hayashi, Kozo, McLeod, David, Zepeda, Carlos, Aman, Ahmed, Sánchez-Osuna, Maria, Bonneil, Eric, Takagi, Shinji, Al-Awar, Rima, Tyers, Mike, Richard, Stephane, Takizawa, Masayuki, Gingras, Anne-Claude, Arrowsmith, Cheryl H, Vedadi, Masoud, Brown, Peter J, Nara, Hiroshi, Barsyte-Lovejoy, Dalia
Published in Nature communications (14.05.2020)
Published in Nature communications (14.05.2020)
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An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death
Garcia-Belinchón, Mercè, Sánchez-Osuna, María, Martínez-Escardó, Laura, Granados-Colomina, Carla, Pascual-Guiral, Sònia, Iglesias-Guimarais, Victoria, Casanelles, Elisenda, Ribas, Judit, Yuste, Victor J.
Published in The Journal of biological chemistry (21.08.2015)
Published in The Journal of biological chemistry (21.08.2015)
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An intrinsic DFF40/CAD endonuclease deficiency impairs oligonucleosomal DNA hydrolysis during caspase-dependent cell death: a common trait in human glioblastoma cells
Sánchez-Osuna, María, Martínez-Escardó, Laura, Granados-Colomina, Carla, Martínez-Soler, Fina, Pascual-Guiral, Sònia, Iglesias-Guimarais, Victoria, Velasco, Roser, Plans, Gerard, Vidal, Noemi, Tortosa, Avelina, Barcia, Carlos, Bruna, Jordi, Yuste, Victor J
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2016)
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Apoptotic DNA Degradation into Oligonucleosomal Fragments, but Not Apoptotic Nuclear Morphology, Relies on a Cytosolic Pool of DFF40/CAD Endonuclease
Iglesias-Guimarais, Victoria, Gil-Guiñon, Estel, Gabernet, Gisela, García-Belinchón, Mercè, Sánchez-Osuna, María, Casanelles, Elisenda, Comella, Joan X., Yuste, Victor J.
Published in The Journal of biological chemistry (02.03.2012)
Published in The Journal of biological chemistry (02.03.2012)
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Caspase-activated DNase Is Necessary and Sufficient for Oligonucleosomal DNA Breakdown, but Not for Chromatin Disassembly during Caspase-dependent Apoptosis of LN-18 Glioblastoma Cells
Sánchez-Osuna, María, Garcia-Belinchón, Mercè, Iglesias-Guimarais, Victoria, Gil-Guiñón, Estel, Casanelles, Elisenda, Yuste, Victor J.
Published in The Journal of biological chemistry (04.07.2014)
Published in The Journal of biological chemistry (04.07.2014)
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NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w
Casanelles, Elisenda, Gozzelino, Raffaella, Marqués-Fernández, Fernando, Iglesias-Guimarais, Victoria, Garcia-Belinchón, Mercè, Sánchez-Osuna, María, Solé, Carme, Moubarak, Rana S., Comella, Joan X., Yuste, Victor J.
Published in Biochimica et biophysica acta (01.05.2013)
Published in Biochimica et biophysica acta (01.05.2013)
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Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response
Szewczyk, Magdalena M, Ishikawa, Yoshinori, Organ, Shawna, Sakai, Nozomu, Li, Fengling, Halabelian, Levon, Ackloo, Suzanne, Couzens, Amber L, Eram, Mohammad, Dilworth, David, Fukushi, Hideto, Harding, Rachel, Dela Seña, Carlo C, Sugo, Tsukasa, Hayashi, Kozo, McLeod, David, Zepeda, Carlos, Aman, Ahmed, Sánchez-Osuna, Maria, Bonneil, Eric, Takagi, Shinji, Al-Awar, Rima, Tyers, Mike, Richard, Stephane, Takizawa, Masayuki, Gingras, Anne-Claude, Arrowsmith, Cheryl H, Vedadi, Masoud, Brown, Peter J, Nara, Hiroshi, Barsyte-Lovejoy, Dalia
Published in Nature communications (26.05.2020)
Published in Nature communications (26.05.2020)
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Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
Michealraj, Kulandaimanuvel Antony, Kumar, Sachin A., Kim, Leo J.Y., Cavalli, Florence M.G., Przelicki, David, Wojcik, John B., Delaidelli, Alberto, Bajic, Andrea, Saulnier, Olivier, MacLeod, Graham, Vellanki, Ravi N., Vladoiu, Maria C., Guilhamon, Paul, Ong, Winnie, Lee, John J.Y., Jiang, Yanqing, Holgado, Borja L., Rasnitsyn, Alex, Malik, Ahmad A., Tsai, Ricky, Richman, Cory M., Juraschka, Kyle, Haapasalo, Joonas, Wang, Evan Y., De Antonellis, Pasqualino, Suzuki, Hiromichi, Farooq, Hamza, Balin, Polina, Kharas, Kaitlin, Van Ommeren, Randy, Sirbu, Olga, Rastan, Avesta, Krumholtz, Stacey L., Ly, Michelle, Ahmadi, Moloud, Deblois, Geneviève, Srikanthan, Dilakshan, Luu, Betty, Loukides, James, Wu, Xiaochong, Garzia, Livia, Ramaswamy, Vijay, Kanshin, Evgeny, Sánchez-Osuna, María, El-Hamamy, Ibrahim, Coutinho, Fiona J., Prinos, Panagiotis, Singh, Sheila, Donovan, Laura K., Daniels, Craig, Schramek, Daniel, Tyers, Mike, Weiss, Samuel, Stein, Lincoln D., Lupien, Mathieu, Wouters, Bradly G., Garcia, Benjamin A., Arrowsmith, Cheryl H., Sorensen, Poul H., Angers, Stephane, Jabado, Nada, Dirks, Peter B., Mack, Stephen C., Agnihotri, Sameer, Rich, Jeremy N., Taylor, Michael D.
Published in Cell (11.06.2020)
Published in Cell (11.06.2020)
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