Amyloid‐β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's disease
Sanchez‐Mico, Maria V., Jimenez, Sebastian, Gomez‐Arboledas, Angela, Muñoz‐Castro, Clara, Romero‐Molina, Carmen, Navarro, Victoria, Sanchez‐Mejias, Elisabeth, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Galea, Elena, Davila, José C., Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in Glia (01.04.2021)
Published in Glia (01.04.2021)
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Journal Article
Neuronally Derived Soluble Abeta Evokes Cell-Wide Astrocytic Calcium Dysregulation in Absence of Amyloid Plaques in Vivo
Kelly, Patricia, Sanchez-Mico, Maria V, Hou, Steven S, Whiteman, Sara, Russ, Alyssa, Hudry, Eloise, Arbel-Ornath, Michal, Greenberg, Steven M, Bacskai, Brian J
Published in The Journal of neuroscience (28.06.2023)
Published in The Journal of neuroscience (28.06.2023)
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Journal Article
Should We Open Fire on Microglia? Depletion Models as Tools to Elucidate Microglial Role in Health and Alzheimer's Disease
Romero-Molina, Carmen, Navarro, Victoria, Jimenez, Sebastian, Muñoz-Castro, Clara, Sanchez-Mico, Maria V, Gutierrez, Antonia, Vitorica, Javier, Vizuete, Marisa
Published in International journal of molecular sciences (08.09.2021)
Published in International journal of molecular sciences (08.09.2021)
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Journal Article
Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s disease
Baglietto-Vargas, David, Sánchez-Mejias, Elisabeth, Navarro, Victoria, Jimenez, Sebastián, Trujillo-Estrada, Laura, Gómez-Arboledas, Angela, Sánchez-Mico, Maria, Sánchez-Varo, Raquel, Vizuete, Marisa, Dávila, José Carlos, García-Verdugo, José Manuel, Vitorica, Javier, Gutierrez, Antonia
Published in Scientific reports (30.08.2017)
Published in Scientific reports (30.08.2017)
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Journal Article
Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease
Gomez‐Arboledas, Angela, Davila, Jose C., Sanchez‐Mejias, Elisabeth, Navarro, Victoria, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Sanchez‐Mico, Maria Virtudes, Trujillo‐Estrada, Laura, Fernandez‐Valenzuela, Juan Jose, Vizuete, Marisa, Comella, Joan X., Galea, Elena, Vitorica, Javier, Gutierrez, Antonia
Published in Glia (01.03.2018)
Published in Glia (01.03.2018)
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Journal Article
Cytotoxicity and Effects on the Synapsis Induced by Pure Cylindrospermopsin in an E17 Embryonic Murine Primary Neuronal Culture in a Concentration- and Time-Dependent Manner
Hinojosa, María G, Prieto, Ana I, Muñoz-Castro, Clara, Sánchez-Mico, María V, Vitorica, Javier, Cameán, Ana M, Jos, Ángeles
Published in Toxins (26.02.2022)
Published in Toxins (26.02.2022)
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Journal Article
Hypoxia compromises the mitochondrial metabolism of Alzheimer's disease microglia via HIF1
March-Diaz, Rosana, Lara-Ureña, Nieves, Romero-Molina, Carmen, Heras-Garvin, Antonio, Ortega-de San Luis, Clara, Alvarez-Vergara, Maria I, Sanchez-Garcia, Manuel A, Sanchez-Mejias, Elisabeth, Davila, Jose C, Rosales-Nieves, Alicia E, Forja, Cristina, Navarro, Victoria, Gomez-Arboledas, Angela, Sanchez-Mico, Maria V, Viehweger, Adrian, Gerpe, Almudena, Hodson, Emma J, Vizuete, Marisa, Bishop, Tammie, Serrano-Pozo, Alberto, Lopez-Barneo, Jose, Berra, Edurne, Gutierrez, Antonia, Vitorica, Javier, Pascual, Alberto
Published in Nature aging (01.04.2021)
Published in Nature aging (01.04.2021)
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Journal Article
Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology
Romero-Molina, Carmen, Navarro, Victoria, Sanchez-Varo, Raquel, Jimenez, Sebastian, Fernandez-Valenzuela, Juan J, Sanchez-Mico, Maria V, Muñoz-Castro, Clara, Gutierrez, Antonia, Vitorica, Javier, Vizuete, Marisa
Published in Frontiers in cellular neuroscience (14.11.2018)
Published in Frontiers in cellular neuroscience (14.11.2018)
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Journal Article
Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages
Taddei, Raquel N, Sanchez-Mico, Maria V, Bonnar, Orla, Connors, Theresa, Gaona, Angelica, Denbow, Dominique, Frosch, Matthew P, Gómez-Isla, Teresa
Published in Acta neuropathologica communications (09.05.2022)
Published in Acta neuropathologica communications (09.05.2022)
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Journal Article
Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration
Sanchez-Mejias, Elisabeth, Navarro, Victoria, Jimenez, Sebastian, Sanchez-Mico, Maria, Sanchez-Varo, Raquel, Nuñez-Diaz, Cristina, Trujillo-Estrada, Laura, Davila, Jose Carlos, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in Acta neuropathologica (01.12.2016)
Published in Acta neuropathologica (01.12.2016)
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Journal Article
Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer's disease
Calvo-Rodriguez, Maria, Kharitonova, Elizabeth K, Snyder, Austin C, Hou, Steven S, Sanchez-Mico, Maria Virtudes, Das, Sudeshna, Fan, Zhanyun, Shirani, Hamid, Nilsson, K Peter R, Serrano-Pozo, Alberto, Bacskai, Brian J
Published in Molecular neurodegeneration (18.01.2024)
Published in Molecular neurodegeneration (18.01.2024)
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Journal Article
Disruption of amyloid plaques integrity affects the soluble oligomers content from Alzheimer disease brains
Jimenez, Sebastian, Navarro, Victoria, Moyano, Javier, Sanchez-Mico, María, Torres, Manuel, Davila, Jose Carlos, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in PloS one (08.12.2014)
Published in PloS one (08.12.2014)
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Journal Article
Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis
Sanchez-Varo, Raquel, Sanchez-Mejias, Elisabeth, Fernandez-Valenzuela, Juan Jose, De Castro, Vanessa, Mejias-Ortega, Marina, Gomez-Arboledas, Angela, Jimenez, Sebastian, Sanchez-Mico, Maria Virtudes, Trujillo-Estrada, Laura, Moreno-Gonzalez, Ines, Baglietto-Vargas, David, Vizuete, Marisa, Davila, Jose Carlos, Vitorica, Javier, Gutierrez, Antonia
Published in Frontiers in neuroscience (04.11.2021)
Published in Frontiers in neuroscience (04.11.2021)
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Journal Article
Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer's disease hippocampus
Muñoz-Castro, Clara, Mejias-Ortega, Marina, Sanchez-Mejias, Elisabeth, Navarro, Victoria, Trujillo-Estrada, Laura, Jimenez, Sebastian, Garcia-Leon, Juan Antonio, Fernandez-Valenzuela, Juan Jose, Sanchez-Mico, Maria Virtudes, Romero-Molina, Carmen, Moreno-Gonzalez, Ines, Baglietto-Vargas, David, Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in Acta neuropathologica communications (28.02.2023)
Published in Acta neuropathologica communications (28.02.2023)
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Journal Article
Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease
Taddei, Raquel N, Perbet, Romain, Mate de Gerando, Anastasie, Wiedmer, Anne E, Sanchez-Mico, Maria, Connors Stewart, Theresa, Gaona, Angelica, Melloni, Alexandra, Amaral, Ana C, Duff, Karen, Frosch, Matthew P, Gómez-Isla, Teresa
Published in Archives of neurology (Chicago) (01.11.2023)
Published in Archives of neurology (Chicago) (01.11.2023)
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Journal Article
Soluble Abeta produces an increase in cytosolic and mitochondrial calcium in astrocytes in vivo, in part by direct effect in astroglial cells
Sanchez‐Mico, Maria V., Calvo‐Rodriguez, Maria, Kelly, Patricia H., Whiteman, Sara, Kharitonova, Elizabeth K., Hou, Steven S., Bacskai, Brian J.
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid [beta] aggregates in vivo in a mouse model of Alzheimer's disease
Calvo-Rodriguez, Maria, Kharitonova, Elizabeth K, Snyder, Austin C, Hou, Steven S, Sanchez-Mico, Maria Virtudes, Das, Sudeshna, Fan, Zhanyun, Shirani, Hamid, Nilsson, K. Peter R, Serrano-Pozo, Alberto, Bacskai, Brian J
Published in Molecular neurodegeneration (18.01.2024)
Published in Molecular neurodegeneration (18.01.2024)
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Journal Article
Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid ß aggregates in vivo in a mouse model of Alzheimer's disease
Calvo-Rodriguez, Maria, Kharitonova, Elizabeth K., Snyder, Austin C., Hou, Steven S., Sanchez-Mico, Maria Virtudes, Das, Sudeshna, Fan, Zhanyun, Shirani, Hamid, Nilsson, Peter, Serrano-Pozo, Alberto, Bacskai, Brian J.
Published in Molecular neurodegeneration (2024)
Published in Molecular neurodegeneration (2024)
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Journal Article
Cover Image, Volume 69, Issue 4
Sanchez‐Mico, Maria V., Jimenez, Sebastian, Gomez‐Arboledas, Angela, Muñoz‐Castro, Clara, Romero‐Molina, Carmen, Navarro, Victoria, Sanchez‐Mejias, Elisabeth, Nuñez‐Diaz, Cristina, Sanchez‐Varo, Raquel, Galea, Elena, Davila, José C., Vizuete, Marisa, Gutierrez, Antonia, Vitorica, Javier
Published in Glia (01.04.2021)
Published in Glia (01.04.2021)
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