Interacting Resident Epicardium-Derived Fibroblasts and Recruited Bone Marrow Cells Form Myocardial Infarction Scar
Ruiz-Villalba, Adrián, PhD, Simón, Ana M., PhD, Pogontke, Cristina, MSc, Castillo, María I., MSc, Abizanda, Gloria, MSc, Pelacho, Beatriz, PhD, Sánchez-Domínguez, Rebeca, PhD, Segovia, José C., PhD, Prósper, Felipe, MD, PhD, Pérez-Pomares, José M., PhD
Published in Journal of the American College of Cardiology (19.05.2015)
Published in Journal of the American College of Cardiology (19.05.2015)
Get full text
Journal Article
Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL
Lahera, Antonio, Vela-Martín, Laura, López-Nieva, Pilar, Salgado, Rocío N, Rodríguez-Perales, Sandra, Torres-Ruiz, Raúl, López-Lorenzo, José L, Cornago, Javier, Llamas, Pilar, Fernández-Navarro, Pablo, Sánchez-Domínguez, Rebeca, Segovia, José C, Sastre, Isabel, Cobos-Fernández, María Á, Menéndez, Pablo, Santos, Javier, Fernández-Piqueras, José, Villa-Morales, María
Published in British journal of haematology (01.08.2023)
Published in British journal of haematology (01.08.2023)
Get full text
Journal Article
TALEN mediated gene editing in a mouse model of Fanconi anemia
Pino-Barrio, Maria José, Giménez, Yari, Villanueva, Mariela, Hildenbeutel, Marcus, Sánchez-Dominguez, Rebeca, Rodríguez-Perales, Sandra, Pujol, Roser, Surrallés, Jordi, Río, Paula, Cathomen, Toni, Mussolino, Claudio, Bueren, Juan Antonio, Navarro, Susana
Published in Scientific reports (24.04.2020)
Published in Scientific reports (24.04.2020)
Get full text
Journal Article
Enhanced Susceptibility of Galectin-1 Deficient Mice to Experimental Colitis
Fernandez-Perez, Raquel, Lopez-Santalla, Mercedes, Sánchez-Domínguez, Rebeca, Alberquilla, Omaira, Gutiérrez-Cañas, Irene, Juarranz, Yasmina, Bueren, Juan A, Garin, Marina I
Published in Frontiers in immunology (28.06.2021)
Published in Frontiers in immunology (28.06.2021)
Get full text
Journal Article
Mesenchymal stromal cells enhance the engraftment of hematopoietic stem cells in an autologous mouse transplantation model
Fernández-García, María, Yañez, Rosa M, Sánchez-Domínguez, Rebeca, Hernando-Rodriguez, Miriam, Peces-Barba, Miguel, Herrera, Guadalupe, O'Connor, Jose E, Segovia, José C, Bueren, Juan A, Lamana, María L
Published in Stem cell research & therapy (07.09.2015)
Published in Stem cell research & therapy (07.09.2015)
Get full text
Journal Article
In Vitro and In Vivo Genetic Disease Modeling via NHEJ-Precise Deletions Using CRISPR-Cas9
López-Manzaneda, Sergio, Ojeda-Pérez, Isabel, Zabaleta, Nerea, García-Torralba, Aída, Alberquilla, Omaira, Torres, Raúl, Sánchez-Domínguez, Rebeca, Torella, Laura, Olivier, Emmanuel, Mountford, Joanne, Ramírez, Juan C., Bueren, Juan A., González-Aseguinolaza, Gloria, Segovia, Jose-Carlos
Published in Molecular therapy. Methods & clinical development (11.12.2020)
Published in Molecular therapy. Methods & clinical development (11.12.2020)
Get full text
Journal Article
Engraftment and in vivo proliferation advantage of gene-corrected mobilized CD34+ cells from Fanconi anemia patients
Río, Paula, Navarro, Susana, Guenechea, Guillermo, Sánchez-Domínguez, Rebeca, Lamana, Maria Luisa, Yañez, Rosa, Casado, Jose A., Mehta, Parinda A., Pujol, Maria Roser, Surrallés, Jordi, Charrier, Sabine, Galy, Anne, Segovia, José C., Díaz de Heredia, Cristina, Sevilla, Julián, Bueren, Juan A.
Published in Blood (28.09.2017)
Published in Blood (28.09.2017)
Get full text
Journal Article
Improved Hematopoietic Gene Therapy in a Mouse Model of Fanconi Anemia Mediated by Mesenchymal Stromal Cells
Fernández-García, María, Luisa Lamana, Maria, Hernando-Rodríguez, Miriam, Sánchez-Domínguez, Rebeca, Bueren, Juan, Yañez, Rosa
Published in Human gene therapy (01.03.2018)
Published in Human gene therapy (01.03.2018)
Get more information
Journal Article
Midkine signaling maintains the self-renewal and tumorigenic capacity of glioma initiating cells
López-Valero, Israel, Dávila, David, González-Martínez, José, Salvador-Tormo, Nélida, Lorente, Mar, Saiz-Ladera, Cristina, Torres, Sofía, Gabicagogeascoa, Estibaliz, Hernández-Tiedra, Sonia, García-Taboada, Elena, Mendiburu-Eliçabe, Marina, Rodríguez-Fornés, Fátima, Sánchez-Domínguez, Rebeca, Segovia, José Carlos, Sánchez-Gómez, Pilar, Matheu, Ander, Sepúlveda, Juan M, Velasco, Guillermo
Published in Theranostics (01.01.2020)
Published in Theranostics (01.01.2020)
Get full text
Journal Article
Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia
Casado, Jose A, Valeri, Antonio, Sanchez-Domínguez, Rebeca, Vela, Paula, Lopez, Andrea, Navarro, Susana, Alberquilla, Omaira, Hanenberg, Helmut, Pujol, Roser, Segovia, Jose C, Minguillón, Jordi, Surrallés, Jordi, Diaz-de-Heredia, Cristina, Sevilla, Julián, Rio, Paula, Bueren, Juan A
Published in The Journal of clinical investigation (01.08.2022)
Published in The Journal of clinical investigation (01.08.2022)
Get full text
Journal Article
Lentivirus-mediated gene therapy corrects ribosomal biogenesis and shows promise for Diamond Blackfan anemia
Giménez, Yari, Palacios, Manuel, Sánchez-Domínguez, Rebeca, Zorbas, Christiane, Peral, Jorge, Puzik, Alexander, Ugalde, Laura, Alberquilla, Omaira, Villanueva, Mariela, Río, Paula, Gálvez, Eva, Da Costa, Lydie, Strullu, Marion, Catala, Albert, Ruiz-Llobet, Anna, Segovia, Jose Carlos, Sevilla, Julián, Strahm, Brigitte, Niemeyer, Charlotte M, Beléndez, Cristina, Leblanc, Thierry, Lafontaine, Denis Lj, Bueren, Juan, Navarro, Susana
Published in JCI insight (22.05.2024)
Published in JCI insight (22.05.2024)
Get full text
Journal Article
Toward Tumor Fight and Tumor Microenvironment Remodeling: PBA Induces Cell Cycle Arrest and Reduces Tumor Hybrid Cells' Pluripotency in Bladder Cancer
Rubio, Carolina, Avendaño-Ortiz, José, Ruiz-Palomares, Raquel, Karaivanova, Viktoriya, Alberquilla, Omaira, Sánchez-Domínguez, Rebeca, Casalvilla-Dueñas, José Carlos, Montalbán-Hernández, Karla, Lodewijk, Iris, Rodríguez-Izquierdo, Marta, Munera-Maravilla, Ester, Nunes, Sandra P, Suárez-Cabrera, Cristian, Pérez-Crespo, Miriam, Martínez, Víctor G, Morales, Lucía, Pérez-Escavy, Mercedes, Alonso-Sánchez, Miguel, Lozano-Rodríguez, Roberto, Cueto, Francisco J, Aguirre, Luis A, Guerrero-Ramos, Félix, Paramio, Jesús M, López-Collazo, Eduardo, Dueñas, Marta
Published in Cancers (07.01.2022)
Published in Cancers (07.01.2022)
Get full text
Journal Article
Clinically relevant gene editing in hematopoietic stem cells for the treatment of pyruvate kinase deficiency
Fañanas-Baquero, Sara, Quintana-Bustamante, Oscar, Dever, Daniel P., Alberquilla, Omaira, Sanchez-Dominguez, Rebeca, Camarena, Joab, Ojeda-Perez, Isabel, Dessy-Rodriguez, Mercedes, Turk, Rolf, Schubert, Mollie S., Lattanzi, Annalisa, Xu, Liwen, Lopez-Lorenzo, Jose L., Bianchi, Paola, Bueren, Juan A., Behlke, Mark A., Porteus, Matthew, Segovia, Jose-Carlos
Published in Molecular therapy. Methods & clinical development (10.09.2021)
Published in Molecular therapy. Methods & clinical development (10.09.2021)
Get full text
Journal Article
Improved collection of hematopoietic stem cells and progenitors from Fanconi anemia patients for gene therapy purposes
Sevilla, Julián, Navarro, Susana, Rio, Paula, Sánchez-Domínguez, Rebeca, Zubicaray, Josune, Gálvez, Eva, Merino, Eva, Sebastián, Elena, Azqueta, Carmen, Casado, José A., Segovia, José C., Alberquilla, Omaira, Bogliolo, Massimo, Román-Rodríguez, Francisco J., Giménez, Yari, Larcher, Lise, Salgado, Rocío, Pujol, Roser M., Hladun, Raquel, Castillo, Ana, Soulier, Jean, Querol, Sergi, Fernández, Jesús, Schwartz, Jonathan, García de Andoín, Nagore, López, Ricardo, Catalá, Albert, Surralles, Jordi, Díaz-de-Heredia, Cristina, Bueren, Juan A.
Published in Molecular therapy. Methods & clinical development (10.09.2021)
Published in Molecular therapy. Methods & clinical development (10.09.2021)
Get full text
Journal Article
Preclinical studies of efficacy thresholds and tolerability of a clinically ready lentiviral vector for pyruvate kinase deficiency treatment
Navarro, Susana, Quintana-Bustamante, Oscar, Sanchez-Dominguez, Rebeca, Lopez-Manzaneda, Sergio, Ojeda-Perez, Isabel, Garcia-Torralba, Aida, Alberquilla, Omaira, Law, Kenneth, Beard, Brian C., Bastone, Antonella, Rothe, Michael, Villanueva, Mariela, Ramirez, Juan C., Fañanas-Baquero, Sara, Nieto-Romero, Virginia, Molinos-Vicente, Andrea, Gutierrez, Sonia, Nicoletti, Eileen, García-Bravo, María, Bueren, Juan A., Schwartz, Jonathan D., Segovia, Jose-Carlos
Published in Molecular therapy. Methods & clinical development (10.09.2021)
Published in Molecular therapy. Methods & clinical development (10.09.2021)
Get full text
Journal Article
Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia
Río, Paula, Navarro, Susana, Wang, Wei, Sánchez-Domínguez, Rebeca, Pujol, Roser M., Segovia, José C., Bogliolo, Massimo, Merino, Eva, Wu, Ning, Salgado, Rocío, Lamana, María L., Yañez, Rosa M., Casado, José A., Giménez, Yari, Román-Rodríguez, Francisco J., Álvarez, Lara, Alberquilla, Omaira, Raimbault, Anna, Guenechea, Guillermo, Lozano, M. Luz, Cerrato, Laura, Hernando, Miriam, Gálvez, Eva, Hladun, Raquel, Giralt, Irina, Barquinero, Jordi, Galy, Anne, García de Andoín, Nagore, López, Ricardo, Catalá, Albert, Schwartz, Jonathan D., Surrallés, Jordi, Soulier, Jean, Schmidt, Manfred, Díaz de Heredia, Cristina, Sevilla, Julián, Bueren, Juan A.
Published in Nature medicine (01.09.2019)
Published in Nature medicine (01.09.2019)
Get full text
Journal Article
Correction of the Energetic Defects in Pyruvate Kinase Deficiency through Genome Editing in Hematopoietic Stem and Progenitor Cells
Fañanas-Baquero, Sara, Quintana Bustamante, Oscar, Dever, Daniel P., Alberquilla, Omaira, Sanchez-Dominguez, Rebeca, Camarena, Joab, Turk, Rolf, López Lorenzo, José Luis, Bianchi, Paola, Behlke, Mark, Bueren, Juan A, Porteus, Matt, Segovia, José C
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
Get full text
Journal Article
Efficient CRISPR/Cas9-Mediated Gene Editing of Pklr in Human Hematopoietic Progenitors and Stem Cells for the Gene Therapy of Pyruvate Kinase Deficiency
Quintana Bustamante, Oscar, Fañanas-Baquero, Sara, Dever, Daniel P., Omaira, Alberquilla, Camarena, Joab, Sanchez-Dominguez, Rebeca, Morin, Matias, Fernandez, Val, Moreno-Pelayo, Miguel Angel, Bueren, Juan A., Porteus, Matthew, Segovia, Jose C
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
Get full text
Journal Article
Hematopoietic Engraftment of Fanconi Anemia Patients through 3 Years after Gene Therapy
Rio, Paula, Navarro, Susana, Sanchez-Dominguez, Rebeca, Segovia, Jose C, Wang, Wei, Merino, Eva, Yañez, Rosa M, Casado, Jose Antonio, Gimenez, Yari A., Roman-Rodriguez, Francisco J, Alberquilla, Omaira, Galvez, Eva, Hladun, Raquel, Barquinero, Jordi, Galy, Anne, García de Andoín, Nagore, López, Ricardo, Catalá, Albert, Cavazzana, Marina, Lefrere, Francois, Leblanc, Thierry, Schwartz, Jonathan D, Pujol, Roser, Surrallés, Jordi, Soulier, Jean, Schmidt, Manfred, Díaz de Heredia, Cristina, Sevilla, Julian, Bueren, Juan A.
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
Get full text
Journal Article
Advances in the Gene Therapy of Patients with Fanconi Anemia
Bueren, Juan A., Navarro, Susana, Wang, Wei, Sanchez-Dominguez, Rebeca, Merino, Eva, Segovia, Jose C, Galy, Anne, Lamana, María L., Yañez, Rosa M, Casado, Jose A, Gimenez, Yari A., Roman-Rodriguez, Francisco J, Alvarez, Lara A., Pujol, Roser, Surralles, Jordi, López, Ricardo, García de Andoín, Nagore, Catala, Albert, Galvez, Eva, Hladun, Raquel, Schwartz, Jonathan D, Schmidt, Manfred, Díaz de Heredia, Cristina, Rio, Paula, Sevilla, Julian
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
Get full text
Journal Article