Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
Schneider, William M., Luna, Joseph M., Hoffmann, H.-Heinrich, Sánchez-Rivera, Francisco J., Leal, Andrew A., Ashbrook, Alison W., Le Pen, Jérémie, Ricardo-Lax, Inna, Michailidis, Eleftherios, Peace, Avery, Stenzel, Ansgar F., Lowe, Scott W., MacDonald, Margaret R., Rice, Charles M., Poirier, John T.
Published in Cell (07.01.2021)
Published in Cell (07.01.2021)
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Rapid modelling of cooperating genetic events in cancer through somatic genome editing
Sánchez-Rivera, Francisco J, Papagiannakopoulos, Thales, Romero, Rodrigo, Tammela, Tuomas, Bauer, Matthew R, Bhutkar, Arjun, Joshi, Nikhil S, Subbaraj, Lakshmipriya, Bronson, Roderick T, Xue, Wen, Jacks, Tyler
Published in Nature (London) (18.12.2014)
Published in Nature (London) (18.12.2014)
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Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
Hoffmann, H.-Heinrich, Sánchez-Rivera, Francisco J., Schneider, William M., Luna, Joseph M., Soto-Feliciano, Yadira M., Ashbrook, Alison W., Le Pen, Jérémie, Leal, Andrew A., Ricardo-Lax, Inna, Michailidis, Eleftherios, Hao, Yuan, Stenzel, Ansgar F., Peace, Avery, Zuber, Johannes, Allis, C. David, Lowe, Scott W., MacDonald, Margaret R., Poirier, John T., Rice, Charles M.
Published in Cell Host & Microbe (10.02.2021)
Published in Cell Host & Microbe (10.02.2021)
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Targeting the De Novo Purine Synthesis Pathway Through Adenylosuccinate Lyase Depletion Impairs Liver Cancer Growth by Perturbing Mitochondrial Function
Jiang, Tingting, Sánchez‐Rivera, Francisco J., Soto‐Feliciano, Yadira M., Yang, Qiyuan, Song, Chun‐Qing, Bhuatkar, Arjun, Haynes, Cole M, Hemann, Michael T., Xue, Wen
Published in Hepatology (Baltimore, Md.) (01.07.2021)
Published in Hepatology (Baltimore, Md.) (01.07.2021)
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SOAT1 promotes mevalonate pathway dependency in pancreatic cancer
Oni, Tobiloba E, Biffi, Giulia, Baker, Lindsey A, Hao, Yuan, Tonelli, Claudia, Somerville, Tim D D, Deschênes, Astrid, Belleau, Pascal, Hwang, Chang-Il, Sánchez-Rivera, Francisco J, Cox, Hilary, Brosnan, Erin, Doshi, Abhishek, Lumia, Rebecca P, Khaledi, Kimia, Park, Youngkyu, Trotman, Lloyd C, Lowe, Scott W, Krasnitz, Alexander, Vakoc, Christopher R, Tuveson, David A
Published in The Journal of experimental medicine (07.09.2020)
Published in The Journal of experimental medicine (07.09.2020)
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Somatic tissue engineering in mouse models reveals an actionable role for WNT pathway alterations in prostate cancer metastasis
Leibold, Josef, Ruscetti, Marcus, Cao, Zhen, Ho, Yu-Jui, Baslan, Timour, Zou, Min, Abida, Wassim, Feucht, Judith, Han, Teng, Barriga, Francisco M, Tsanov, Kaloyan M, Zamechek, Leah, Kulick, Amanda, Amor, Corina, Tian, Sha, Rybczyk, Katarzyna, Salgado, Nelson R, Sanchez-Rivera, Francisco J, Watson, Philip A, de Stanchina, Elisa, Wilkinson, John E, Dow, Lukas E, Abate-Shen, Cory, Sawyers, Charles L, Lowe, Scott W
Published in Cancer discovery (01.07.2020)
Published in Cancer discovery (01.07.2020)
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A Gain-of-Function p53-Mutant Oncogene Promotes Cell Fate Plasticity and Myeloid Leukemia through the Pluripotency Factor FOXH1
Loizou, Evangelia, Banito, Ana, Livshits, Geulah, Ho, Yu-Jui, Koche, Richard P, Sánchez-Rivera, Francisco J, Mayle, Allison, Chen, Chi-Chao, Kinalis, Savvas, Bagger, Frederik O, Kastenhuber, Edward R, Durham, Benjamin H, Lowe, Scott W
Published in Cancer discovery (01.07.2019)
Published in Cancer discovery (01.07.2019)
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Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma
Chen, Xiao, Li, Yinglu, Zhu, Fang, Xu, Xinjing, Estrella, Brian, Pazos, 2nd, Manuel A, McGuire, John T, Karagiannis, Dimitris, Sahu, Varun, Mustafokulov, Mustafo, Scuoppo, Claudio, Sánchez-Rivera, Francisco J, Soto-Feliciano, Yadira M, Pasqualucci, Laura, Ciccia, Alberto, Amengual, Jennifer E, Lu, Chao
Published in Nature communications (17.07.2023)
Published in Nature communications (17.07.2023)
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Phase and context shape the function of composite oncogenic mutations
Gorelick, Alexander N, Sánchez-Rivera, Francisco J, Cai, Yanyan, Bielski, Craig M, Biederstedt, Evan, Jonsson, Philip, Richards, Allison L, Vasan, Neil, Penson, Alexander V, Friedman, Noah D, Ho, Yu-Jui, Baslan, Timour, Bandlamudi, Chaitanya, Scaltriti, Maurizio, Schultz, Nikolaus, Lowe, Scott W, Reznik, Ed, Taylor, Barry S
Published in Nature (London) (01.06.2020)
Published in Nature (London) (01.06.2020)
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Metabolic reprogramming by histone deacetylase inhibition preferentially targets NRF2-activated tumors
Karagiannis, Dimitris, Wu, Warren, Li, Albert, Hayashi, Makiko, Chen, Xiao, Yip, Michaela, Mangipudy, Vaibhav, Xu, Xinjing, Sánchez-Rivera, Francisco J., Soto-Feliciano, Yadira M., Ye, Jiangbin, Papagiannakopoulos, Thales, Lu, Chao
Published in Cell reports (Cambridge) (23.01.2024)
Published in Cell reports (Cambridge) (23.01.2024)
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PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes
Soto-Feliciano, Yadira M, Bartlebaugh, Jordan M E, Liu, Yunpeng, Sánchez-Rivera, Francisco J, Bhutkar, Arjun, Weintraub, Abraham S, Buenrostro, Jason D, Cheng, Christine S, Regev, Aviv, Jacks, Tyler E, Young, Richard A, Hemann, Michael T
Published in Genes & development (15.05.2017)
Published in Genes & development (15.05.2017)
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Optimized base editors enable efficient editing in cells, organoids and mice
Zafra, Maria Paz, Schatoff, Emma M, Katti, Alyna, Foronda, Miguel, Breinig, Marco, Schweitzer, Anabel Y, Simon, Amber, Han, Teng, Goswami, Sukanya, Montgomery, Emma, Thibado, Jordana, Kastenhuber, Edward R, Sánchez-Rivera, Francisco J, Shi, Junwei, Vakoc, Christopher R, Lowe, Scott W, Tschaharganeh, Darjus F, Dow, Lukas E
Published in Nature biotechnology (01.10.2018)
Published in Nature biotechnology (01.10.2018)
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α-Ketoglutarate links p53 to cell fate during tumour suppression
Morris, 4th, John P, Yashinskie, Jossie J, Koche, Richard, Chandwani, Rohit, Tian, Sha, Chen, Chi-Chao, Baslan, Timour, Marinkovic, Zoran S, Sánchez-Rivera, Francisco J, Leach, Steven D, Carmona-Fontaine, Carlos, Thompson, Craig B, Finley, Lydia W S, Lowe, Scott W
Published in Nature (London) (26.09.2019)
Published in Nature (London) (26.09.2019)
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Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis
Romero, Rodrigo, Sayin, Volkan I, Davidson, Shawn M, Bauer, Matthew R, Singh, Simranjit X, LeBoeuf, Sarah E, Karakousi, Triantafyllia R, Ellis, Donald C, Bhutkar, Arjun, Sánchez-Rivera, Francisco J, Subbaraj, Lakshmipriya, Martinez, Britney, Bronson, Roderick T, Prigge, Justin R, Schmidt, Edward E, Thomas, Craig J, Goparaju, Chandra, Davies, Angela, Dolgalev, Igor, Heguy, Adriana, Allaj, Viola, Poirier, John T, Moreira, Andre L, Rudin, Charles M, Pass, Harvey I, Vander Heiden, Matthew G, Jacks, Tyler, Papagiannakopoulos, Thales
Published in Nature medicine (01.11.2017)
Published in Nature medicine (01.11.2017)
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STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma
Hu, Jing, Sánchez-Rivera, Francisco J, Wang, Zhenghan, Johnson, Gabriela N, Ho, Yu-Jui, Ganesh, Karuna, Umeda, Shigeaki, Gan, Siting, Mujal, Adriana M, Delconte, Rebecca B, Hampton, Jessica P, Zhao, Huiyong, Kottapalli, Sanjay, de Stanchina, Elisa, Iacobuzio-Donahue, Christine A, Pe'er, Dana, Lowe, Scott W, Sun, Joseph C, Massagué, Joan
Published in Nature (London) (27.04.2023)
Published in Nature (London) (27.04.2023)
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Deconstructing cancer with precision genome editing
Johnson, Grace A, Gould, Samuel I, Sánchez-Rivera, Francisco J
Published in Biochemical Society transactions (24.04.2024)
Published in Biochemical Society transactions (24.04.2024)
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Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants
Sánchez-Rivera, Francisco J, Diaz, Bianca J, Kastenhuber, Edward R, Schmidt, Henri, Katti, Alyna, Kennedy, Margaret, Tem, Vincent, Ho, Yu-Jui, Leibold, Josef, Paffenholz, Stella V, Barriga, Francisco M, Chu, Kevan, Goswami, Sukanya, Wuest, Alexandra N, Simon, Janelle M, Tsanov, Kaloyan M, Chakravarty, Debyani, Zhang, Hongxin, Leslie, Christina S, Lowe, Scott W, Dow, Lukas E
Published in Nature biotechnology (01.06.2022)
Published in Nature biotechnology (01.06.2022)
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How CRISPR Is Revolutionizing the Generation of New Models for Cancer Research
Sánchez Rivera, Francisco J, Dow, Lukas E
Published in Cold Spring Harbor perspectives in medicine (01.05.2024)
Published in Cold Spring Harbor perspectives in medicine (01.05.2024)
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High-throughput evaluation of genetic variants with prime editing sensor libraries
Gould, Samuel I, Wuest, Alexandra N, Dong, Kexin, Johnson, Grace A, Hsu, Alvin, Narendra, Varun K, Atwa, Ondine, Levine, Stuart S, Liu, David R, Sánchez Rivera, Francisco J
Published in Nature biotechnology (12.03.2024)
Published in Nature biotechnology (12.03.2024)
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