High thermostability improves neutralizing antibody responses induced by native-like HIV-1 envelope trimers
del Moral-Sánchez, Iván, Russell, Rebecca A., Schermer, Edith E., Cottrell, Christopher A., Allen, Joel D., Torrents de la Peña, Alba, LaBranche, Celia C., Kumar, Sanjeev, Crispin, Max, Ward, Andrew B., Montefiori, David C., Sattentau, Quentin J., Sliepen, Kwinten, Sanders, Rogier W.
Published in npj vaccines (28.02.2022)
Published in npj vaccines (28.02.2022)
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Induction of cross-neutralizing antibodies by a permuted hepatitis C virus glycoprotein nanoparticle vaccine candidate
Sliepen, Kwinten, Radić, Laura, Capella-Pujol, Joan, Watanabe, Yasunori, Zon, Ian, Chumbe, Ana, Lee, Wen-Hsin, de Gast, Marlon, Koopsen, Jelle, Koekkoek, Sylvie, del Moral-Sánchez, Iván, Brouwer, Philip J. M., Ravichandran, Rashmi, Ozorowski, Gabriel, King, Neil P., Ward, Andrew B., van Gils, Marit J., Crispin, Max, Schinkel, Janke, Sanders, Rogier W.
Published in Nature communications (25.11.2022)
Published in Nature communications (25.11.2022)
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Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines
del Moral-Sánchez, Iván, Wee, Edmund G., Xian, Yuejiao, Lee, Wen-Hsin, Allen, Joel D., Torrents de la Peña, Alba, Fróes Rocha, Rebeca, Ferguson, James, León, André N., Koekkoek, Sylvie, Schermer, Edith E., Burger, Judith A., Kumar, Sanjeev, Zwolsman, Robby, Brinkkemper, Mitch, Aartse, Aafke, Eggink, Dirk, Han, Julianna, Yuan, Meng, Crispin, Max, Ozorowski, Gabriel, Ward, Andrew B., Wilson, Ian A., Hanke, Tomáš, Sliepen, Kwinten, Sanders, Rogier W.
Published in npj vaccines (06.04.2024)
Published in npj vaccines (06.04.2024)
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Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle
Brouwer, Philip J. M., Antanasijevic, Aleksandar, Berndsen, Zachary, Yasmeen, Anila, Fiala, Brooke, Bijl, Tom P. L., Bontjer, Ilja, Bale, Jacob B., Sheffler, William, Allen, Joel D., Schorcht, Anna, Burger, Judith A., Camacho, Miguel, Ellis, Daniel, Cottrell, Christopher A., Behrens, Anna-Janina, Catalano, Marco, del Moral-Sánchez, Iván, Ketas, Thomas J., LaBranche, Celia, van Gils, Marit J., Sliepen, Kwinten, Stewart, Lance J., Crispin, Max, Montefiori, David C., Baker, David, Moore, John P., Klasse, Per Johan, Ward, Andrew B., King, Neil P., Sanders, Rogier W.
Published in Nature communications (19.09.2019)
Published in Nature communications (19.09.2019)
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Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
Medina-Ramírez, Max, Garces, Fernando, Escolano, Amelia, Skog, Patrick, de Taeye, Steven W, Del Moral-Sanchez, Ivan, McGuire, Andrew T, Yasmeen, Anila, Behrens, Anna-Janina, Ozorowski, Gabriel, van den Kerkhof, Tom L G M, Freund, Natalia T, Dosenovic, Pia, Hua, Yuanzi, Gitlin, Alexander D, Cupo, Albert, van der Woude, Patricia, Golabek, Michael, Sliepen, Kwinten, Blane, Tanya, Kootstra, Neeltje, van Breemen, Mariëlle J, Pritchard, Laura K, Stanfield, Robyn L, Crispin, Max, Ward, Andrew B, Stamatatos, Leonidas, Klasse, Per Johan, Moore, John P, Nemazee, David, Nussenzweig, Michel C, Wilson, Ian A, Sanders, Rogier W
Published in The Journal of experimental medicine (04.09.2017)
Published in The Journal of experimental medicine (04.09.2017)
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Convergent HIV-1 Evolution upon Targeted Destabilization of the gp120-gp41 Interface
Torrents de la Peña, Alba, Del Moral Sánchez, Iván, Burger, Judith A, Bontjer, Ilja, Isik, Gözde, Eggink, Dirk, van Gils, Marit J, Sanders, Rogier W
Published in Journal of virology (23.11.2021)
Published in Journal of virology (23.11.2021)
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Mosaic and mixed HIV-1 glycoprotein nanoparticles elicit antibody responses to broadly neutralizing epitopes
Brinkkemper, Mitch, Kerster, Gius, Brouwer, Philip J M, Tran, Andy S, Torres, Jonathan L, Ettema, Roos A, Nijhuis, Haye, Allen, Joel D, Zhu, Wenwen, Gao, Hongmei, Lee, Wen-Hsin, Bijl, Tom P L, Snitselaar, Jonne L, Burger, Judith A, Bontjer, Ilja, Olijhoek, Wouter, Ravichandran, Rashmi, van Breemen, Marielle J, Del Moral-Sánchez, Iván, Derking, Ronald, Sliepen, Kwinten, Ozorowski, Gabriel, Crispin, Max, Montefiori, David C, Claireaux, Mathieu, Ward, Andrew B, van Gils, Marit J, King, Neil P, Sanders, Rogier W
Published in PLoS pathogens (03.10.2024)
Published in PLoS pathogens (03.10.2024)
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Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions
Caniels, Tom G., Medina-Ramírez, Max, Zhang, Jinsong, Sarkar, Anita, Kumar, Sonu, LaBranche, Alex, Derking, Ronald, Allen, Joel D., Snitselaar, Jonne L., Capella-Pujol, Joan, Sánchez, Iván del Moral, Yasmeen, Anila, Diaz, Marilyn, Aldon, Yoann, Bijl, Tom P.L., Venkatayogi, Sravani, Martin Beem, Joshua S., Newman, Amanda, Jiang, Chuancang, Lee, Wen-Hsin, Pater, Maarten, Burger, Judith A., van Breemen, Mariëlle J., de Taeye, Steven W., Rantalainen, Kimmo, LaBranche, Celia, Saunders, Kevin O., Montefiori, David, Ozorowski, Gabriel, Ward, Andrew B., Crispin, Max, Moore, John P., Klasse, Per Johan, Haynes, Barton F., Wilson, Ian A., Wiehe, Kevin, Verkoczy, Laurent, Sanders, Rogier W.
Published in Cell reports. Medicine (18.04.2023)
Published in Cell reports. Medicine (18.04.2023)
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Journal Article
Germline-targeting HIV vaccination induces neutralizing antibodies to the CD4 binding site
Caniels, Tom G, Medina-Ramìrez, Max, Zhang, Shiyu, Kratochvil, Sven, Xian, Yuejiao, Koo, Ja-Hyun, Derking, Ronald, Samsel, Jakob, van Schooten, Jelle, Pecetta, Simone, Lamperti, Edward, Yuan, Meng, Carrasco, María Ríos, Del Moral Sánchez, Iván, Allen, Joel D, Bouhuijs, Joey H, Yasmeen, Anila, Ketas, Thomas J, Snitselaar, Jonne L, Bijl, Tom P L, Martin, Isabel Cuella, Torres, Jonathan L, Cupo, Albert, Shirreff, Lisa, Rogers, Kenneth, Mason, Rosemarie D, Roederer, Mario, Greene, Kelli M, Gao, Hongmei, Silva, Catarina Mendes, Baken, Isabel J L, Tian, Ming, Alt, Frederick W, Pulendran, Bali, Seaman, Michael S, Crispin, Max, van Gils, Marit J, Montefiori, David C, McDermott, Adrian B, Villinger, François J, Koup, Richard A, Moore, John P, Klasse, Per Johan, Ozorowski, Gabriel, Batista, Facundo D, Wilson, Ian A, Ward, Andrew B, Sanders, Rogier W
Published in Science immunology (30.08.2024)
Published in Science immunology (30.08.2024)
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Design and immunogenicity of an HIV-1 clade C pediatric envelope glycoprotein stabilized by multiple platforms
Kumar, Sanjeev, Del Moral-Sánchez, Iván, Singh, Swarandeep, Newby, Maddy L, Allen, Joel D, Bijl, Tom P L, Vaghani, Yog, Jing, Liang, Ortlund, Eric A, Crispin, Max, Patel, Anamika, Sanders, Rogier W, Luthra, Kalpana
Published in bioRxiv (19.09.2024)
Published in bioRxiv (19.09.2024)
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The molecular immune modulator adenosine deaminase-1 enhances HIV specific humoral and cellular responses to a native-like HIV envelope trimer DNA vaccine
Kutzler, Michele A, Cusimano, Gina, Joyner, David, Konopka, Emily, Muir, Roshell, Barnette, Philip, Guderian, Melanie, Del Moral-Sánchez, Iván, Derking, Ronald, Bijl, Tom, Snitselaar, Jonne, Rotsides, Photis, Woloszczuk, Kyra, Bell, Matthew, Canziani, Gabriela, Chaiken, Irwin, Hessell, Ann, Bartsch, Yannic, Sanders, Rogier, Haddad, Elias
Published in Research square (22.04.2024)
Published in Research square (22.04.2024)
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Journal Article
Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
Medina-Ramírez, Max, Garces, Fernando, Escolano, Amelia, Skog, Patrick, de Taeye, Steven W., Del Moral-Sanchez, Ivan, McGuire, Andrew T., Yasmeen, Anila, Behrens, Anna-Janina, Ozorowski, Gabriel, van den Kerkhof, Tom L. G. M., Freund, Natalia T., Dosenovic, Pia, Hua, Yuanzi, Gitlin, Alexander D., Cupo, Albert, van der Woude, Patricia, Golabek, Michael, Sliepen, Kwinten, Blane, Tanya, Kootstra, Neeltje, van Breemen, Mariëlle J., Pritchard, Laura K., Stanfield, Robyn L., Crispin, Max, Ward, Andrew B., Stamatatos, Leonidas, Klasse, Per Johan, Moore, John P., Nemazee, David, Nussenzweig, Michel C., Wilson, Ian A., Sanders, Rogier W.
Published in The Journal of experimental medicine (28.08.2017)
Published in The Journal of experimental medicine (28.08.2017)
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