A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responses
Agrez, Michael, Rzepecka, Justyna, Turner, Darryl, Knox, Gavin, Chandler, Christopher, Howard, Christopher B., Fletcher, Nicholas, Thurecht, Kristofer, Parker, Stephen, Gooding, Hayley, Gallagher, Laura
Published in Scientific reports (01.07.2022)
Published in Scientific reports (01.07.2022)
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Journal Article
The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17-producing cellular network at multiple sites
Pineda, Miguel A., McGrath, Mairi A., Smith, Pauline C., Al-Riyami, Lamyaa, Rzepecka, Justyna, Gracie, J. Alastair, Harnett, William, Harnett, Margaret M.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.10.2012)
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Journal Article
An immunomodulating peptide with potential to suppress tumour growth and autoimmunity
Agrez, Michael, Chandler, Christopher, Thurecht, Kristofer J., Fletcher, Nicholas L., Liu, Feifei, Subramaniam, Gayathri, Howard, Christopher B., Blyth, Benjamin, Parker, Stephen, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew M., Gooding, Hayley, Gallagher, Laura
Published in Scientific reports (13.11.2023)
Published in Scientific reports (13.11.2023)
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Journal Article
An immunomodulating peptide to counteract solar radiation-induced immunosuppression and DNA damage
Agrez, Michael, Rybchyn, Mark Stephen, De Silva, Warusavithana Gunawardena Manori, Mason, Rebecca Sara, Chandler, Christopher, Piva, Terrence J., Thurecht, Kristofer, Fletcher, Nicholas, Liu, Feifei, Subramaniam, Gayathri, Howard, Christopher B., Blyth, Benjamin, Parker, Stephen, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew, Gooding, Hayley, Gallagher, Laura
Published in Scientific reports (20.07.2023)
Published in Scientific reports (20.07.2023)
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Journal Article
Functional Analysis of Effector and Regulatory T Cells in a Parasitic Nematode Infection
Rausch, Sebastian, Huehn, Jochen, Kirchhoff, Dennis, Rzepecka, Justyna, Schnoeller, Corinna, Pillai, Smitha, Loddenkemper, Christoph, Scheffold, Alexander, Hamann, Alf, Lucius, Richard, Hartmann, Susanne
Published in Infection and Immunity (01.05.2008)
Published in Infection and Immunity (01.05.2008)
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Journal Article
251 The use of small molecule inhibitors to target novel pathways in exhausted T cells for immuno-oncology therapeutic intervention
Acklam, Francis, Hay, Joanne, Turner, Darryl, Barbour, Mark, Singh, Preeti, Grant, Courtney, Gooding, Hayley, Rzepecka, Justyna, McPherson, Rhoanne
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88
Melendez, Alirio J, Puneet, Padmam, McGrath, Mairi A, Tay, Hwee Kee, Al-Riyami, Lamyaa, Rzepecka, Justyna, Moochhala, Shabbir M, Pervaiz, Shazib, Harnett, Margaret M, Harnett, William
Published in Nature immunology (01.04.2011)
Published in Nature immunology (01.04.2011)
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Journal Article
Mast Cell Subsets and Their Functional Modulation by the Acanthocheilonema viteae Product ES-62
Ball, Dimity H., Tay, Hwee Kee, Bell, Kara S., Coates, Michelle L., al-Riyami, Lamyaa, Rzepecka, Justyna, Harnett, William, Harnett, Margaret M.
Published in Journal of Parasitology Research (2013)
Published in Journal of Parasitology Research (2013)
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Journal Article
Abstract A122: Deciphering macrophage targeting cancer immunotherapies using a novel in vitro assay modelling the tumor microenvironment
Turner, Darryl, Dobie, Ross, Rzepecka, Justyna, Gooding, Hayley, Bingham, Matilda
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Journal Article
Abstract LB158: Implications of Targeting Novel Pathways in Exhausted T Cells for Immuno-Oncology Therapeutic Intervention
McPherson, Rhoanne, Acklam, Francis, Hay, Joanne, Barbour, Mark, Grant, Courtney, Singh, Preeti, Gambardella, Adriana, Rzepecka, Justyna, Anderton, Stephen, Gooding, Hayley
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
A novel immunomodulating peptide with potential to complement oligodeoxynucleotide-mediated adjuvanticity in vaccination strategies
Agrez, Michael, Chandler, Christopher, Thurecht, Kristofer J., Fletcher, Nicholas L., Liu, Feifei, Subramaniam, Gayathri, Howard, Christopher B., Parker, Stephen, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew M., Gooding, Hayley, Gallagher, Laura
Published in Scientific reports (05.11.2024)
Published in Scientific reports (05.11.2024)
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Journal Article
Designing Anti-inflammatory Drugs from Parasitic Worms: A Synthetic Small Molecule Analogue of the Acanthocheilonema viteae Product ES-62 Prevents Development of Collagen-Induced Arthritis
Al-Riyami, Lamyaa, Pineda, Miguel A, Rzepecka, Justyna, Huggan, Judith K, Khalaf, Abedawn I, Suckling, Colin J, Scott, Fraser J, Rodgers, David T, Harnett, Margaret M, Harnett, William
Published in Journal of medicinal chemistry (27.12.2013)
Published in Journal of medicinal chemistry (27.12.2013)
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Journal Article
The Parasitic Worm Product ES‐62 Targets Myeloid Differentiation Factor 88–Dependent Effector Mechanisms to Suppress Antinuclear Antibody Production and Proteinuria in MRL/lpr Mice
Rodgers, David T., McGrath, Mairi A., Pineda, Miguel A., Al‐Riyami, Lamyaa, Rzepecka, Justyna, Lumb, Felicity, Harnett, William, Harnett, Margaret M.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2015)
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Journal Article
Taking The Autoimmune Sting Out Of Pd-1 Checkpoint Inhibition to Suppress Cancer Growth
Agrez, Michael, Parker, Stephen, Chandler, Christopher, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew, Gooding, Hayley, Gallagher, Laura
Published in European journal of rheumatology (11.05.2024)
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Published in European journal of rheumatology (11.05.2024)
Journal Article
Autoimmunity and Endometriosis: Potential Relevance of A Novel Immunomodulating Compound
Agrez, Michael, Chandler, Christopher, Turner, Darryl, Nika, Anastasia, Hall, Andrew, Gallagher, Laura, Gooding, Hayley, Rzepecka, Justyna, Knox, Gavin, Parker, Stephen
Published in European journal of rheumatology (11.05.2024)
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Published in European journal of rheumatology (11.05.2024)
Journal Article
Autoimmunity and Endometriosis: Potential Relevance of A Novel Immunomodulating Compound
Agrez, Michael, Chandler, Christopher, Turner, Darryl, Nika, Anastasia, Hall, Andrew, Gallagher, Laura, Gooding, Hayley, Rzepecka, Justyna, Knox, Gavin, Parker, Stephen
Published in European journal of rheumatology (01.05.2024)
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Published in European journal of rheumatology (01.05.2024)
Journal Article
Taking The Autoimmune Sting Out Of Pd-1 Checkpoint Inhibition to Suppress Cancer Growth
Agrez, Michael, Parker, Stephen, Chandler, Christopher, Turner, Darryl, Rzepecka, Justyna, Knox, Gavin, Nika, Anastasia, Hall, Andrew, Gooding, Hayley, Gallagher, Laura
Published in European journal of rheumatology (01.05.2024)
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Published in European journal of rheumatology (01.05.2024)
Journal Article
Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome
Rzepecka, Justyna, Pineda, Miguel A, Al-Riyami, Lamyaa, Rodgers, David T, Huggan, Judith K, Lumb, Felicity E, Khalaf, Abedawn I, Meakin, Paul J, Corbet, Marlene, Ashford, Michael L, Suckling, Colin J, Harnett, Margaret M, Harnett, William
Published in Journal of autoimmunity (01.06.2015)
Published in Journal of autoimmunity (01.06.2015)
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Journal Article
The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype
Rzepecka, Justyna, Siebeke, Ivonne, Coltherd, Jennifer C., Kean, Dorothy E., Steiger, Christina N., Al-Riyami, Lamyaa, McSharry, Charles, Harnett, Margaret M., Harnett, William
Published in International journal for parasitology (01.03.2013)
Published in International journal for parasitology (01.03.2013)
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