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Published in Journal of medicinal chemistry (26.07.2007)
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Synthesis and structure-activity relationships of pyridine-modified analogs of 3-[2-(( S)-pyrrolidinyl)methoxy]pyridine, A-84543, a potent nicotinic acetylcholine receptor agonist
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Published in Bioorganic & medicinal chemistry letters (03.02.1998)
Published in Bioorganic & medicinal chemistry letters (03.02.1998)
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Syntheses and structure–activity relationship (SAR) studies of 2,5-diazabicyclo[2.2.1]heptanes as novel α7 neuronal nicotinic receptor (NNR) ligands
Li, Tao, Bunnelle, William H., Ryther, Keith B., Anderson, David J., Malysz, John, Helfrich, Rosalind, Grønlien, Jens H., Håkerud, Monika, Peters, Dan, Schrimpf, Michael R., Gopalakrishnan, Murali, Ji, Jianguo
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
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Functional Characterization of the Novel Neuronal Nicotinic Acetylcholine Receptor Ligand GTS-21 In Vitro and In Vivo
Briggs, Clark A, Anderson, David J, Brioni, Jorge D, Buccafusco, Jerry J, Buckley, Michael J, Campbell, Jeffrey E, Decker, Michael W, DONNELLY–ROBERTS, Diana, Elliott, Richard L, Gopalakrishnan, Murali, Holladay, Mark W, Hui, Yu-Hua, Jackson, William J, Kim, David J.B, Marsh, Kennan C, O'Neill, Alyssa, Prendergast, Mark A, Ryther, Keith B, Sullivan, James P, Arneric, Stephen P
Published in Pharmacology, biochemistry and behavior (01.05.1997)
Published in Pharmacology, biochemistry and behavior (01.05.1997)
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Identification and Initial Structure−Activity Relationships of (R)-5-(2-Azetidinylmethoxy)-2-chloropyridine (ABT-594), a Potent, Orally Active, Non-Opiate Analgesic Agent Acting via Neuronal Nicotinic Acetylcholine Receptors
Holladay, Mark W, Wasicak, James T, Lin, Nan-Horng, He, Yun, Ryther, Keith B, Bannon, Anthony W, Buckley, Michael J, Kim, David J. B, Decker, Michael W, Anderson, David J, Campbell, Jeffrey E, Kuntzweiler, Theresa A, Donnelly-Roberts, Diana L, Piattoni-Kaplan, Marietta, Briggs, Clark A, Williams, Michael, Arneric, Stephen P
Published in Journal of medicinal chemistry (12.02.1998)
Published in Journal of medicinal chemistry (12.02.1998)
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ABT-089 [2-Methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A Potent and Selective Cholinergic Channel Modulator with Neuroprotective Properties
Sullivan, J P, Donnelly-Roberts, D, Briggs, C A, Anderson, D J, Gopalakrishnan, M, Xue, I C, Piattoni-Kaplan, M, Molinari, E, Campbell, J E, McKenna, D G, Gunn, D E, Lin, N H, Ryther, K B, He, Y, Holladay, M W, Wonnacott, S, Williams, M, Arneric, S P
Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.1997)
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Structure−Activity Studies on 2-Methyl-3-(2(S)-pyrrolidinylmethoxy)pyridine (ABT-089): An Orally Bioavailable 3-Pyridyl Ether Nicotinic Acetylcholine Receptor Ligand with Cognition-Enhancing Properties
Lin, Nan-Horng, Gunn, David E, Ryther, Keith B, Garvey, David S, Donnelly-Roberts, Diana L, Decker, Michael W, Brioni, Jorge D, Buckley, Michael J, Rodrigues, A. David, Marsh, Kennan G, Anderson, David J, Buccafusco, Jerry J, Prendergast, Mark A, Sullivan, James P, Williams, Michael, Arneric, Stephen P, Holladay, Mark W
Published in Journal of medicinal chemistry (31.01.1997)
Published in Journal of medicinal chemistry (31.01.1997)
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Efficient asymmetric synthesis of ABT-594; a potent, orally effective analgesic
Lynch, John K., Holladay, Mark W., Ryther, Keith B., Bai, Hao, Hsiao, Chi-Nung, Morton, Howard E., Dickman, Daniel A., Arnold, William, King, Steven A.
Published in Tetrahedron: asymmetry (21.08.1998)
Published in Tetrahedron: asymmetry (21.08.1998)
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Syntheses and structure-activity relationship (SAR) studies of 2,5-diazabicyclo[2.2.1]heptanes as novel alpha7 neuronal nicotinic receptor (NNR) ligands
Li, Tao, Bunnelle, William H, Ryther, Keith B, Anderson, David J, Malysz, John, Helfrich, Rosalind, Grønlien, Jens H, Håkerud, Monika, Peters, Dan, Schrimpf, Michael R, Gopalakrishnan, Murali, Ji, Jianguo
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
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Structure-activity studies related to ABT-594, a potent nonopioid analgesic agent: Effect of pyridine and azetidine ring substitutions on nicotinic acetylcholine receptor binding affinity and analgesic activity in mice
Holladay, Mark W., Bai, Hao, Li, Yihong, Lin, Nan-Horng, Daanen, Jerome F., Ryther, Keith B., Wasicak, James T., Kincaid, John F., He, Yun, Hettinger, Anne-Marie, Huang, Peggy, Anderson, David J., Bannon, Anthony W., Buckley, Michael J., Campbell, Jeffrey E., Donnelly-Roberts, Diana L., Gunther, Karen L., Kim, David J.B., Kuntzweiler, Theresa A., Sullivan, James P., Decker, Michael W., Arneric, Stephen P.
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
Published in Bioorganic & medicinal chemistry letters (06.10.1998)
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Structural aspects of high affinity ligands for the α4β2 neuronal nicotinic receptor
Dart, Michael J., Wasicak, James T., Ryther, Keith B., Schrimpf, Michael R., Kim, Ki H., Anderson, David J., Sullivan, James P., Meyer, Michael D.
Published in Pharmaceutica acta Helvetiae (01.03.2000)
Published in Pharmaceutica acta Helvetiae (01.03.2000)
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Novel 2-(2′-furo[3,2- b]pyridinyl) pyrrolidines: potent neuronal nicotinic acetylcholine receptor ligands
Elliott, Richard L., Ryther, Keith B., Anderson, David J., Piattoni-Kaplan, Marietta, Kuntzweiler, Theresa A., Donnelly-Roberts, Diana, Arneric, Stephen P., Holladay, Mark W.
Published in Bioorganic & medicinal chemistry letters (04.11.1997)
Published in Bioorganic & medicinal chemistry letters (04.11.1997)
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2-(Aryloxymethyl) azacyclic analogues as novel nicotinic acetylcholine receptor (nAChR) ligands
Elliott, Richard L., Kopecka, Hana, Gunn, David E., Lin, Nan-Horng, Garvey, David S., Ryther, Keith B., Holladay, Mark W., Anderson, David J., Campbell, Jeffrey E., Sullivan, James P., Buckley, Michael J., Gunther, Karen L., O'Neill, Alyssa B., Decker, Michael W., Arnerić, Stephen P.
Published in Bioorganic & medicinal chemistry letters (08.10.1996)
Published in Bioorganic & medicinal chemistry letters (08.10.1996)
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Phenyl pyrrolidine analogues as potent nicotinic acetylcholine receptor (nAChR) ligands
Elliott, Richard L., Ryther, Keith B., Anderson, David J., Raszkiewicz, Joanna L., Campbell, Jeffrey E., Sullivan, James P., Garvey, David S.
Published in Bioorganic & medicinal chemistry letters (04.05.1995)
Published in Bioorganic & medicinal chemistry letters (04.05.1995)
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Year of Publication 02.08.2017
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Year of Publication 02.08.2017
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NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF
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Year of Publication 20.08.2015
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Year of Publication 14.04.2015
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Compounds as cannabinoid receptor ligands and uses thereof
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Year of Publication 23.09.2014
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Year of Publication 23.09.2014
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Compounds as cannabinoid receptor ligands and uses thereof
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Year of Publication 01.10.2013
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Year of Publication 01.10.2013
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