alpha.-Hydroxy Phosphinyl-Based Inhibitors of Human Renin
Patel, Dinesh V, Rielly-Gauvin, Katherine, Ryono, Denis E, Free, Charles A, Rogers, W. Lynn, Smith, Sandra A, DeForrest, Jack M, Oehl, Robert S, Petrillo, Edward W
Published in Journal of medicinal chemistry (01.10.1995)
Published in Journal of medicinal chemistry (01.10.1995)
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Vasopeptidase Inhibitors: Incorporation of Geminal and Spirocyclic Substituted Azepinones in Mercaptoacyl Dipeptides
Robl, Jeffrey A, Sulsky, Richard, Sieber-McMaster, Ellen, Ryono, Denis E, Cimarusti, Maria P, Simpkins, Ligaya M, Karanewsky, Donald S, Chao, Sam, Asaad, Magdi M, Seymour, Andrea A, Fox, Maxine, Smith, Patricia L, Trippodo, Nick C
Published in Journal of medicinal chemistry (28.01.1999)
Published in Journal of medicinal chemistry (28.01.1999)
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Activated ketone based inhibitors of human renin
Patel, Dinesh V, Rielly-Gauvin, Katherine, Ryono, Denis E, Free, Charles A, Smith, Sandra A, Petrillo, Edward W
Published in Journal of medicinal chemistry (20.08.1993)
Published in Journal of medicinal chemistry (20.08.1993)
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BMS‐180560, an insurmountable inhibitor of angiotensin II‐stimulated responses: comparison with losartan and EXP3174
Dickinson, K.E.J., Cohen, R.B., Skwish, S., Delaney, C.L., Serafino, R.P., Poss, M.A., Gu, Z., Ryono, D.E., Moreland, S., Powell, J.R.
Published in British journal of pharmacology (01.09.1994)
Published in British journal of pharmacology (01.09.1994)
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Prodrugs of BMS-183920: Metabolism and Permeability Considerations
Obermeier, Mary T., Chong, Saeho, Dando, Sandra A., Marino, Anthony M., Ryono, Denis E., Starrett-Arroyo, Anne, DiDonato, Gerald C., Warrack, Bethanne M., White, Ronald E., Morrison, Richard A.
Published in Journal of pharmaceutical sciences (01.08.1996)
Published in Journal of pharmaceutical sciences (01.08.1996)
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Dual Metalloprotease Inhibitors: Mercaptoacetyl-Based Fused Heterocyclic Dipeptide Mimetics as Inhibitors of Angiotensin-Converting Enzyme and Neutral Endopeptidase
Robl, Jeffrey A, Sun, Chong-Qing, Stevenson, Jay, Ryono, Denis E, Simpkins, Ligaya M, Cimarusti, Maria P, Dejneka, Tamara, Slusarchyk, William A, Chao, Sam, Stratton, Leslie, Misra, Raj N, Bednarz, Mark S, Asaad, Magdi M, Cheung, Hong Son, Abboa-Offei, Benoni E, Smith, Patricia L, Mathers, Parker D, Fox, Maxine, Schaeffer, Thomas R, Seymour, Andrea A, Trippodo, Nick C
Published in Journal of medicinal chemistry (23.05.1997)
Published in Journal of medicinal chemistry (23.05.1997)
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Orally active prodrugs of quinoline-4-carboxylic acid angiotensin II receptor antagonists
Ryono, D.E., Lloyd, J., Poss, M.A., Bird, J.E., Buote, J., Chong, S., Dejneka, T., Dickinson, K.E.J., Gu, Z., Mathers, P., Moreland, S., Morrison, R.A., Petrillo, E.W., Powell, J.R., Schaeffer, T., Spitzmiller, E.R., White, R.E.
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
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Quinoline-4-carboxylic acids as angiotensin II receptor antagonists
Lloyd, J., Ryono, D.E., Bird, J.E., Buote, J., Delaney, C.L., Dejneka, T., Dickinson, K.E.J., Moreland, S., Normandin, D.E., Skwish, S., Spitzmiller, E.R., Waldron, T.L.
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
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Dual Metalloprotease Inhibitors. 6. Incorporation of Bicyclic and Substituted Monocyclic Azepinones as Dipeptide Surrogates in Angiotensin-Converting Enzyme/Neutral Endopeptidase Inhibitors
Robl, Jeffrey A, Cimarusti, Maria P, Simpkins, Ligaya M, Brown, Baerbel, Ryono, Denis E, Bird, J. Eileen, Asaad, Magdi M, Schaeffer, Thomas R, Trippodo, Nick C
Published in Journal of medicinal chemistry (19.01.1996)
Published in Journal of medicinal chemistry (19.01.1996)
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Streptomyces R61 dd-carboxypeptidase: Hydrolysis of X- d-alanyl- d-alanine peptides measured by a fluorometric assay
Georgopapadakou, Nafsika H., Liu, Fung Y., Ryono, Denis E., Neubeck, Richard, Gordon, Eric M., Pluscec, Jelka
Published in Analytical biochemistry (01.02.1984)
Published in Analytical biochemistry (01.02.1984)
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Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines
Krapcho, John, Turk, Chester, Cushman, David W, Powell, James R, DeForrest, Jack M, Spitzmiller, Ervin R, Karanewsky, Donald S, Duggan, Mark, Rovnyak, George
Published in Journal of medicinal chemistry (01.06.1988)
Published in Journal of medicinal chemistry (01.06.1988)
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1,4-substituted indoles: a potent and selective class of angiotensin II receptor antagonists
POSS, M. A, ZHENGXIANG GU, DELANEY, C. L, EILEEN BIRD, J, WALDRON, T. L, SCHAEFFER, T. R, ANDERS HEDBERG, S, PETRILLO, E. W, RYONO, D. E, REID, J. A, SIEBER-MCMASTER, E, SPITZMILLER, E. R, DEJNEKA, T, DICKINSON, K. E. J, WILLIAMS, S. B, MORELAND, S
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
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Diol sulfonamides: A potent and novel class of inhibitors of human renin
Poss, Michael A., Reid, Joyce A., Free, Charles A., Rogers, W.Lynn, Weber, Helen, Ryono, Denis E., Dejneka, Tamara, DeForrest, Jack M., Waldron, Thomas L., Brittain, Russell J., Weller, Harold N., Cimarusti, Maria P., Petrillo, Edward W.
Published in Bioorganic & medicinal chemistry letters (01.12.1993)
Published in Bioorganic & medicinal chemistry letters (01.12.1993)
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Design and Synthesis of N-[(4-Methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a Novel Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist with Efficacious Glucose and Lipid-Lowering Activities
Devasthale, Pratik V, Chen, Sean, Jeon, Yoon, Qu, Fucheng, Shao, Chunning, Wang, Wei, Zhang, Hao, Cap, Michael, Farrelly, Dennis, Golla, Rajasree, Grover, Gary, Harrity, Thomas, Ma, Zhengping, Moore, Lisa, Ren, Jimmy, Seethala, Ramakrishna, Cheng, Lin, Sleph, Paul, Sun, Wei, Tieman, Aaron, Wetterau, John R, Doweyko, Arthur, Chandrasena, Gamini, Chang, Shu Y, Humphreys, W. Griffith, Sasseville, Vito G, Biller, Scott A, Ryono, Denis E, Selan, Fred, Hariharan, Narayanan, Cheng, Peter T. W
Published in Journal of medicinal chemistry (24.03.2005)
Published in Journal of medicinal chemistry (24.03.2005)
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Angiotensin-converting enzyme inhibitors: importance of the amide carbonyl of mercaptoacyl amino acids for hydrogen bonding to the enzyme
Condon, Michael E, Petrillo, Edward W, Ryono, Denis E, Reid, Joyce A, Neubeck, Richard, Puar, Mohindar, Heikes, James E, Sabo, Emily F, Losee, Kathryn A
Published in Journal of medicinal chemistry (01.03.1982)
Published in Journal of medicinal chemistry (01.03.1982)
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Pharmacology of novel imidazole alcohol inhibitors of primate renin
DeForrest, J M, Waldron, T L, Oehl, R S, Scalese, R J, Free, C A, Weller, H N, Ryono, D E
Published in Journal of hypertension. Supplement (01.04.1989)
Published in Journal of hypertension. Supplement (01.04.1989)
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