TRPM2 channels mediate acetaminophen-induced liver damage
Kheradpezhouh, Ehsan, Ma, Linlin, Morphett, Arthur, Barritt, Greg J., Rychkov, Grigori Y.
Published in Proceedings of the National Academy of Sciences - PNAS (25.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.02.2014)
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Drosophila expressing mutant human KCNT1 transgenes make an effective tool for targeted drug screening in a whole animal model of KCNT1-epilepsy
Hussain, Rashid, Lim, Chiao Xin, Shaukat, Zeeshan, Islam, Anowarul, Caseley, Emily A., Lippiat, Jonathan D., Rychkov, Grigori Y., Ricos, Michael G., Dibbens, Leanne M.
Published in Scientific reports (09.02.2024)
Published in Scientific reports (09.02.2024)
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Journal Article
Steatosis inhibits liver cell store-operated Ca²⁺ entry and reduces ER Ca²⁺ through a protein kinase C-dependent mechanism
Wilson, Claire H, Ali, Eunüs S, Scrimgeour, Nathan, Martin, Alyce M, Hua, Jin, Tallis, George A, Rychkov, Grigori Y, Barritt, Greg J
Published in Biochemical journal (01.03.2015)
Published in Biochemical journal (01.03.2015)
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Journal Article
The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuli
Brierley, Stuart M, Hughes, Patrick A, Page, Amanda J, Kwan, Kelvin Y, Martin, Christopher M, O'Donnell, Tracey A, Cooper, Nicole J, Harrington, Andrea M, Adam, Birgit, Liebregts, Tobias, Holtmann, Gerald, Corey, David P, Rychkov, Grigori Y, Blackshaw, L Ashley
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2009)
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Journal Article
TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity
Brierley, Stuart M., Castro, Joel, Harrington, Andrea M., Hughes, Patrick A., Page, Amanda J., Rychkov, Grigori Y., Blackshaw, L. Ashley
Published in The Journal of physiology (15.07.2011)
Published in The Journal of physiology (15.07.2011)
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Journal Article
Functional Effects of Epilepsy Associated KCNT1 Mutations Suggest Pathogenesis via Aberrant Inhibitory Neuronal Activity
Rychkov, Grigori Y, Shaukat, Zeeshan, Lim, Chiao Xin, Hussain, Rashid, Roberts, Ben J, Bonardi, Claudia M, Rubboli, Guido, Meaney, Brandon F, Whitney, Robyn, Møller, Rikke S, Ricos, Michael G, Dibbens, Leanne M
Published in International journal of molecular sciences (01.12.2022)
Published in International journal of molecular sciences (01.12.2022)
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Journal Article
Expression and function of TRP channels in liver cells
Rychkov, Grigori Y, Barritt, Gregory J
Published in Advances in experimental medicine and biology (01.01.2011)
Published in Advances in experimental medicine and biology (01.01.2011)
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Journal Article
Neurogenic potential of dental pulp stem cells isolated from murine incisors
Ellis, Kylie M, O'Carroll, David C, Lewis, Martin D, Rychkov, Grigori Y, Koblar, Simon A
Published in Stem cell research & therapy (27.02.2014)
Published in Stem cell research & therapy (27.02.2014)
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Journal Article
Modulation of TRP Channel Activity by Hydroxylation and Its Therapeutic Potential
Nagarajan, Yagnesh, Rychkov, Grigori Y, Peet, Daniel J
Published in Pharmaceuticals (Basel, Switzerland) (27.03.2017)
Published in Pharmaceuticals (Basel, Switzerland) (27.03.2017)
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Journal Article
Movement of hClC-1 C-termini during common gating and limits on their cytoplasmic location
Ma, Linlin, Rychkov, Grigori Y, Bykova, Ekaterina A, Zheng, Jie, Bretag, Allan H
Published in Biochemical journal (01.06.2011)
Published in Biochemical journal (01.06.2011)
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Journal Article
Cytoplasmic ATP-sensing Domains Regulate Gating of Skeletal Muscle ClC-1 Chloride Channels
Bennetts, Brett, Rychkov, Grigori Y., Ng, Hooi-Ling, Morton, Craig J., Stapleton, David, Parker, Michael W., Cromer, Brett A.
Published in The Journal of biological chemistry (16.09.2005)
Published in The Journal of biological chemistry (16.09.2005)
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Journal Article
A small component of the endoplasmic reticulum is required for store-operated Ca2+ channel activation in liver cells: evidence from studies using TRPV1 and taurodeoxycholic acid
Castro, Joel, Aromataris, Edoardo C, Rychkov, Grigori Y, Barritt, Greg J
Published in Biochemical journal (15.03.2009)
Published in Biochemical journal (15.03.2009)
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Journal Article
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
Osteen, Jeremiah D., Herzig, Volker, Gilchrist, John, Emrick, Joshua J., Zhang, Chuchu, Wang, Xidao, Castro, Joel, Garcia-Caraballo, Sonia, Grundy, Luke, Rychkov, Grigori Y., Weyer, Andy D., Dekan, Zoltan, Undheim, Eivind A. B., Alewood, Paul, Stucky, Cheryl L., Brierley, Stuart M., Basbaum, Allan I., Bosmans, Frank, King, Glenn F., Julius, David
Published in Nature (London) (23.06.2016)
Published in Nature (London) (23.06.2016)
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Journal Article
Orai1‐ and Orai2‐, but not Orai3‐mediated ICRAC is regulated by intracellular pH
Rychkov, Grigori Y., Zhou, Fiona H., Adams, Melissa K., Brierley, Stuart M., Ma, Linlin, Barritt, Greg J.
Published in The Journal of physiology (01.02.2022)
Published in The Journal of physiology (01.02.2022)
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