Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model
Wing, Peter A C, Prange-Barczynska, Maria, Cross, Amy, Crotta, Stefania, Orbegozo Rubio, Claudia, Cheng, Xiaotong, Harris, James M, Zhuang, Xiaodong, Johnson, Rachel L, Ryan, Kathryn A, Hall, Yper, Carroll, Miles W, Issa, Fadi, Balfe, Peter, Wack, Andreas, Bishop, Tammie, Salguero, Francisco J, McKeating, Jane A
Published in PLoS pathogens (06.09.2022)
Published in PLoS pathogens (06.09.2022)
Get full text
Journal Article
Intranasal Infection of Ferrets with SARS-CoV-2 as a Model for Asymptomatic Human Infection
Everett, Helen E, Lean, Fabian Z X, Byrne, Alexander M P, van Diemen, Pauline M, Rhodes, Shelley, James, Joe, Mollett, Benjamin, Coward, Vivien J, Skinner, Paul, Warren, Caroline J, Bewley, Kevin R, Watson, Samantha, Hurley, Shellene, Ryan, Kathryn A, Hall, Yper, Simmons, Hugh, Núñez, Alejandro, Carroll, Miles W, Brown, Ian H, Brookes, Sharon M
Published in Viruses (15.01.2021)
Published in Viruses (15.01.2021)
Get full text
Journal Article
Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
Proud, Pamela C., Tsitoura, Daphne, Watson, Robert J., Chua, Brendon Y., Aram, Marilyn J., Bewley, Kevin R., Cavell, Breeze E., Cobb, Rebecca, Dowall, Stuart, Fotheringham, Susan A., Ho, Catherine M.K., Lucas, Vanessa, Ngabo, Didier, Rayner, Emma, Ryan, Kathryn A., Slack, Gillian S., Thomas, Stephen, Wand, Nadina I., Yeates, Paul, Demaison, Christophe, Zeng, Weiguang, Holmes, Ian, Jackson, David C., Bartlett, Nathan W., Mercuri, Francesca, Carroll, Miles W.
Published in EBioMedicine (01.01.2021)
Published in EBioMedicine (01.01.2021)
Get full text
Journal Article
Web Resource
Cellular immune response to human influenza viruses differs between H1N1 and H3N2 subtypes in the ferret lung
Ryan, Kathryn A, Slack, Gillian S, Marriott, Anthony C, Kane, Jennifer A, Whittaker, Catherine J, Silman, Nigel J, Carroll, Miles W, Gooch, Karen E
Published in PloS one (07.09.2018)
Published in PloS one (07.09.2018)
Get full text
Journal Article
SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum
Handley, Alastair, Ryan, Kathryn A, Davies, Elizabeth R, Bewley, Kevin R, Carnell, Oliver T, Challis, Amy, Coombes, Naomi S, Fotheringham, Susan A, Gooch, Karen E, Charlton, Michael, Harris, Debbie J, Kennard, Chelsea, Ngabo, Didier, Weldon, Thomas M, Salguero, Francisco J, Funnell, Simon G P, Hall, Yper
Published in Viruses (01.03.2023)
Published in Viruses (01.03.2023)
Get full text
Journal Article
The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection
Davies, Elizabeth R, Ryan, Kathryn A, Bewley, Kevin R, Coombes, Naomi S, Salguero, Francisco J, Carnell, Oliver T, Biddlecombe, Sarah, Charlton, Michael, Challis, Amy, Cross, Eleanor S, Handley, Alastair, Ngabo, Didier, Weldon, Thomas M, Hall, Yper, Funnell, Simon G P
Published in Viruses (10.05.2023)
Published in Viruses (10.05.2023)
Get full text
Journal Article
Influenza A Virus Challenge Models in Cynomolgus Macaques Using the Authentic Inhaled Aerosol and Intra-Nasal Routes of Infection
Marriott, Anthony C, Dennis, Mike, Kane, Jennifer A, Gooch, Karen E, Hatch, Graham, Sharpe, Sally, Prevosto, Claudia, Leeming, Gail, Zekeng, Elsa-Gayle, Staples, Karl J, Hall, Graham, Ryan, Kathryn A, Bate, Simon, Moyo, Nathifa, Whittaker, Catherine J, Hallis, Bassam, Silman, Nigel J, Lalvani, Ajit, Wilkinson, Tom M, Hiscox, Julian A, Stewart, James P, Carroll, Miles W
Published in PloS one (01.06.2016)
Published in PloS one (01.06.2016)
Get full text
Journal Article
Infection with Seasonal H1N1 Influenza Results in Comparable Disease Kinetics and Host Immune Responses in Ferrets and Golden Syrian Hamsters
Paterson, Jemma, Ryan, Kathryn A, Morley, Daniel, Jones, Nicola J, Yeates, Paul, Hall, Yper, Whittaker, Catherine J, Salguero, Francisco J, Marriott, Anthony C
Published in Pathogens (Basel) (30.04.2023)
Published in Pathogens (Basel) (30.04.2023)
Get full text
Journal Article
Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir
Marriott, Anthony C, Dove, Brian K, Whittaker, Catherine J, Bruce, Christine, Ryan, Kathryn A, Bean, Thomas J, Rayner, Emma, Pearson, Geoff, Taylor, Irene, Dowall, Stuart, Plank, Jenna, Newman, Edmund, Barclay, Wendy S, Dimmock, Nigel J, Easton, Andrew J, Hallis, Bassam, Silman, Nigel J, Carroll, Miles W
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
Get full text
Journal Article
Relationship of TIMI myocardial perfusion grade to mortality after administration of thrombolytic drugs
GIBSON, C. M, CANNON, C. P, MURPHY, S. A, RYAN, K. A, MESLEY, R, MARBLE, S. J, MCCABE, C. H, VAN DE WERF, F, BRAUNWALD, E
Published in Circulation (New York, N.Y.) (18.01.2000)
Published in Circulation (New York, N.Y.) (18.01.2000)
Get full text
Journal Article
Severity of heterosubtypic influenza virus infection in ferrets is reduced by live attenuated influenza vaccine
Marriott, Anthony C., Gooch, Karen E., Brown, Phillip J., Ryan, Kathryn A., Jones, Nicola J., Merredew, Natasha, Wiblin, Nathan, Dibben, Oliver, Bright, Helen, Hallis, Bassam, Whittaker, Catherine J., Carroll, Miles W.
Published in npj vaccines (29.03.2021)
Published in npj vaccines (29.03.2021)
Get full text
Journal Article
Relationship between TIMI frame count and clinical outcomes after thrombolytic administration
GIBSON, C. M, MURPHY, S. A, RIZZO, M. J, RYAN, K. A, MARBLE, S. J, MCCABE, C. H, CANNON, C. P, DE WERF, F. V, BRAUNWALD, E
Published in Circulation (New York, N.Y.) (20.04.1999)
Published in Circulation (New York, N.Y.) (20.04.1999)
Get full text
Journal Article
Sequential Delivery of Live Attenuated Influenza Vaccine and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the Ferret Model Can Reduce SARS-CoV-2 Shedding and Does Not Result in Enhanced Lung Pathology
Ryan, Kathryn A, Schewe, Katarzyna E, Crowe, Jonathan, Fotheringham, Susan A, Hall, Yper, Humphreys, Richard, Marriott, Anthony C, Paterson, Jemma, Rayner, Emma, Salguero, Francisco J, Watson, Robert J, Whittaker, Catherine J, Carroll, Miles W, Dibben, Oliver
Published in The Journal of infectious diseases (01.02.2022)
Published in The Journal of infectious diseases (01.02.2022)
Get full text
Journal Article
Impaired coronary blood flow in nonculprit arteries in the setting of acute myocardial infarction
Gibson, C.Michael, Ryan, Kathryn A, Murphy, Sabina A, Mesley, Rebecca, Marble, Susan J, Giugliano, Robert P, Cannon, Christopher P, Antman, Elliott M, Braunwald, Eugene
Published in Journal of the American College of Cardiology (01.10.1999)
Published in Journal of the American College of Cardiology (01.10.1999)
Get full text
Journal Article
One or two dose regimen of the SARS-CoV-2 synthetic DNA vaccine INO-4800 protects against respiratory tract disease burden in nonhuman primate challenge model
Gooch, Karen E., Smith, Trevor R.F., Salguero, Francisco J., Fotheringham, Susan A., Watson, Robert J., Dennis, Mike J., Handley, Alastair, Humphries, Holly E., Longet, Stephanie, Tipton, Tom, Sarfas, Charlotte, Sibley, Laura, Slack, Gillian S., Rayner, Emma, Ryan, Kathryn A., Schultheis, Katherine, Ramos, Stephanie J., White, Andrew, Charlton, Sue, Sharpe, Sally A., Gleeson, Fergus, Humeau, Laurent M., Hall, Yper, Broderick, Kate E., Carroll, Miles W.
Published in Vaccine (09.08.2021)
Published in Vaccine (09.08.2021)
Get full text
Journal Article
Heterosubtypic cross-protection correlates with cross-reactive interferon-gamma-secreting lymphocytes in the ferret model of influenza
Gooch, Karen E., Marriott, Anthony C., Ryan, Kathryn A., Yeates, Paul, Slack, Gillian S., Brown, Phillip J., Fothergill, Ross, Whittaker, Catherine J., Carroll, Miles W.
Published in Scientific reports (22.02.2019)
Published in Scientific reports (22.02.2019)
Get full text
Journal Article
Determinants of coronary blood flow after thrombolytic administration
Gibson, C.Michael, Murphy, Sabina, Menown, Ian B.A., Sequeira, Rafael F., Greene, Robert, Van de Werf, Frans, Schweiger, Marc J., Ghali, Magdi, Frey, Martin J., Ryan, Kathryn A., Marble, Susan J., Giugliano, Robert P., Antman, Elliott M., Cannon, Christopher P., Braunwald, Eugene
Published in Journal of the American College of Cardiology (01.11.1999)
Published in Journal of the American College of Cardiology (01.11.1999)
Get full text
Journal Article
Sequential delivery of LAIV and SARS-CoV-2 in the ferret model can reduce SARS-CoV-2 shedding and does not result in enhanced lung pathology
Ryan, Kathryn A, Schewe, Katarzyna E, Crowe, Jonathan, Fotheringham, Susan A, Hall, Yper, Humphreys, Richard, Marriott, Anthony C, Paterson, Jemma, Rayner, Emma, Salguero, Francisco J, Watson, Robert J, Whittaker, Catherine J, Carroll, Miles W, Dibben, Oliver
Published in The Journal of infectious diseases (11.12.2021)
Published in The Journal of infectious diseases (11.12.2021)
Get full text
Journal Article
Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant
Ryan, Kathryn A, Bewley, Kevin R, Watson, Robert J, Burton, Christopher, Carnell, Oliver, Cavell, Breeze E, Challis, Amy, Coombes, Naomi S, Davies, Elizabeth R, Edun-Huges, Jack, Emery, Kirsty, Fell, Rachel, Fotheringham, Susan A, Gooch, Karen E, Gowan, Kathryn, Handley, Alastair, Harris, Debbie J, Hesp, Richard, Hunter, Laura, Humphreys, Richard, Johnson, Rachel, Kennard, Chelsea, Knott, Daniel, Lister, Sian, Morley, Daniel, Ngabo, Didier, Osman, Karen L, Paterson, Jemma, Penn, Elizabeth J, Pullan, Steven T, Richards, Kevin S, Summers, Sian, Thomas, Stephen R, Weldon, Thomas, Wiblin, Nathan R, Rayner, Emma L, Vipond, Richard T, Hallis, Bassam, Salguero, Francisco J, Funnell, Simon G P, Hall, Yper
Published in PLoS pathogens (01.04.2023)
Published in PLoS pathogens (01.04.2023)
Get full text
Journal Article
Keto/Enol Epoxy Steroids as HIV-1 Tat Inhibitors: Structure-Activity Relationships and Pharmacophore Localization
Michne, William F, Schroeder, Joseph D, Bailey, Thomas R, Neumann, Helmut C, Cooke, Debra, Young, Dorothy C, Hughes, Joseph V, Kingsley, Susan D, Ryan, Kathryn A, Putz, Henry S, Shaw, Lucinda J, Dutko, Frank J
Published in Journal of medicinal chemistry (01.08.1995)
Published in Journal of medicinal chemistry (01.08.1995)
Get full text
Journal Article