Pediatric low-grade glioma in the era of molecular diagnostics
Ryall, Scott, Tabori, Uri, Hawkins, Cynthia
Published in Acta neuropathologica communications (12.03.2020)
Published in Acta neuropathologica communications (12.03.2020)
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Journal Article
Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer
Pajovic, Sanja, Siddaway, Robert, Bridge, Taylor, Sheth, Javal, Rakopoulos, Patricia, Kim, Byungjin, Ryall, Scott, Agnihotri, Sameer, Phillips, Lauren, Yu, Man, Li, Christopher, Milos, Scott, Patel, Palak, Srikanthan, Dilakshan, Huang, Annie, Hawkins, Cynthia
Published in Nature communications (04.12.2020)
Published in Nature communications (04.12.2020)
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Journal Article
Splicing is an alternate oncogenic pathway activation mechanism in glioma
Siddaway, Robert, Milos, Scott, Vadivel, Arun Kumaran Anguraj, Dobson, Tara H. W., Swaminathan, Jyothishmathi, Ryall, Scott, Pajovic, Sanja, Patel, Palak G., Nazarian, Javad, Becher, Oren, Brudno, Michael, Ramani, Arun, Gopalakrishnan, Vidya, Hawkins, Cynthia
Published in Nature communications (31.01.2022)
Published in Nature communications (31.01.2022)
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Journal Article
Multiplex Detection of Pediatric Low-Grade Glioma Signature Fusion Transcripts and Duplications Using the NanoString nCounter System
Ryall, Scott, Arnoldo, Anthony, Krishnatry, Rahul, Mistry, Matthew, Khor, Kangzi, Sheth, Javal, Ling, Cino, Leung, Stephie, Zapotocky, Michal, Guerreiro Stucklin, Ana, Lassaletta, Alvaro, Shago, Mary, Tabori, Uri, Hawkins, Cynthia E.
Published in Journal of neuropathology and experimental neurology (01.07.2017)
Published in Journal of neuropathology and experimental neurology (01.07.2017)
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Journal Article
Immuno-oncologic profiling of pediatric brain tumors reveals major clinical significance of the tumor immune microenvironment
Levine, Adrian B., Nobre, Liana, Das, Anirban, Milos, Scott, Bianchi, Vanessa, Johnson, Monique, Fernandez, Nicholas R., Stengs, Lucie, Ryall, Scott, Ku, Michelle, Rana, Mansuba, Laxer, Benjamin, Sheth, Javal, Sbergio, Stefanie-Grace, Fedoráková, Ivana, Ramaswamy, Vijay, Bennett, Julie, Siddaway, Robert, Tabori, Uri, Hawkins, Cynthia
Published in Nature communications (10.07.2024)
Published in Nature communications (10.07.2024)
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Journal Article
Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics
Hoffman, Lindsey M, DeWire, Mariko, Ryall, Scott, Buczkowicz, Pawel, Leach, James, Miles, Lili, Ramani, Arun, Brudno, Michael, Kumar, Shiva Senthil, Drissi, Rachid, Dexheimer, Phillip, Salloum, Ralph, Chow, Lionel, Hummel, Trent, Stevenson, Charles, Lu, Q Richard, Jones, Blaise, Witte, David, Aronow, Bruce, Hawkins, Cynthia E, Fouladi, Maryam
Published in Acta neuropathologica communications (04.01.2016)
Published in Acta neuropathologica communications (04.01.2016)
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Journal Article
The Clinical Utility of a Tiered Approach to Pediatric Glioma Molecular Characterization for Resource-Limited Settings
Hammad, Rawan, Nobre, Liana, Ryall, Scott, Arnoldo, Anthony, Siddaway, Robert, Bennett, Julie, Tabori, Uri, Hawkins, Cynthia
Published in JCO global oncology (01.05.2024)
Published in JCO global oncology (01.05.2024)
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Journal Article
Clinical and molecular characterization of a multi-institutional cohort of pediatric spinal cord low-grade gliomas
Grob, Sydney T, Nobre, Liana, Campbell, Kristen R, Davies, Kurtis D, Ryall, Scott, Aisner, Dara L, Hoffman, Lindsey, Zahedi, Shadi, Morin, Andrew, Crespo, Michele, Nellan, Anandani, Green, Adam L, Foreman, Nicholas, Vibhakar, Rajeev, Hankinson, Todd C, Handler, Michael H, Hawkins, Cynthia, Tabori, Uri, Kleinschmidt-DeMasters, B K, Mulcahy Levy, Jean M
Published in Neuro-oncology advances (01.01.2020)
Published in Neuro-oncology advances (01.01.2020)
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Journal Article
Erratum: Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics
Hoffman, Lindsey M, DeWire, Mariko, Ryall, Scott, Buczkowicz, Pawel, Leach, James, Miles, Lili, Ramani, Arun K, Brudno, Michael, Kumar, Shiva Senthil, Drissi, Rachid, Dexheimer, Phillip, Salloum, Ralph, Chow, Lionel, Hummel, Trent, Stevenson, Charles, Lu, Q Richard, Jones, Blaise, Witte, David, Aronow, Bruce, Hawkins, Cynthia E, Fouladi, Maryam
Published in Acta neuropathologica communications (09.02.2016)
Published in Acta neuropathologica communications (09.02.2016)
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Journal Article
Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas
Ryall, Scott, Zapotocky, Michal, Fukuoka, Kohei, Nobre, Liana, Guerreiro Stucklin, Ana, Bennett, Julie, Siddaway, Robert, Li, Christopher, Pajovic, Sanja, Arnoldo, Anthony, Kowalski, Paul E., Johnson, Monique, Sheth, Javal, Lassaletta, Alvaro, Tatevossian, Ruth G., Orisme, Wilda, Qaddoumi, Ibrahim, Surrey, Lea F., Li, Marilyn M., Waanders, Angela J., Gilheeney, Stephen, Rosenblum, Marc, Bale, Tejus, Tsang, Derek S., Laperriere, Normand, Kulkarni, Abhaya, Ibrahim, George M., Drake, James, Dirks, Peter, Taylor, Michael D., Rutka, James T., Laughlin, Suzanne, Shroff, Manohar, Shago, Mary, Hazrati, Lili-Naz, D'Arcy, Colleen, Ramaswamy, Vijay, Bartels, Ute, Huang, Annie, Bouffet, Eric, Karajannis, Matthias A., Santi, Mariarita, Ellison, David W., Tabori, Uri, Hawkins, Cynthia
Published in Cancer cell (13.04.2020)
Published in Cancer cell (13.04.2020)
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Journal Article
Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas
Guerreiro Stucklin, Ana S., Ryall, Scott, Fukuoka, Kohei, Zapotocky, Michal, Lassaletta, Alvaro, Li, Christopher, Bridge, Taylor, Kim, Byungjin, Arnoldo, Anthony, Kowalski, Paul E., Zhong, Yvonne, Johnson, Monique, Li, Claire, Ramani, Arun K., Siddaway, Robert, Nobre, Liana Figueiredo, de Antonellis, Pasqualino, Dunham, Christopher, Cheng, Sylvia, Boué, Daniel R., Finlay, Jonathan L., Coven, Scott L., de Prada, Inmaculada, Perez-Somarriba, Marta, Faria, Claudia, Grotzer, Michael A., Rushing, Elisabeth, Sumerauer, David, Zamecnik, Josef, Krskova, Lenka, Garcia Ariza, Miguel, Cruz, Ofelia, Morales La Madrid, Andres, Solano, Palma, Terashima, Keita, Nakano, Yoshiko, Ichimura, Koichi, Nagane, Motoo, Sakamoto, Hiroaki, Gil-da-Costa, Maria Joao, Silva, Roberto, Johnston, Donna L., Michaud, Jean, Wilson, Bev, van Landeghem, Frank K. H., Oviedo, Angelica, McNeely, P. Daniel, Crooks, Bruce, Fried, Iris, Zhukova, Nataliya, Hansford, Jordan R., Nageswararao, Amulya, Garzia, Livia, Shago, Mary, Brudno, Michael, Irwin, Meredith S., Bartels, Ute, Ramaswamy, Vijay, Bouffet, Eric, Taylor, Michael D., Tabori, Uri, Hawkins, Cynthia
Published in Nature communications (25.09.2019)
Published in Nature communications (25.09.2019)
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Journal Article
Targeting reduced mitochondrial DNA quantity as a therapeutic approach in pediatric high-grade gliomas
Shen, Han, Yu, Man, Tsoli, Maria, Chang, Cecilia, Joshi, Swapna, Liu, Jie, Ryall, Scott, Chornenkyy, Yevgen, Siddaway, Robert, Hawkins, Cynthia, Ziegler, David S
Published in Neuro-oncology (Charlottesville, Va.) (11.01.2020)
Published in Neuro-oncology (Charlottesville, Va.) (11.01.2020)
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Journal Article
DIPG-86. INVESTIGATING THE TUMOR ENVIRONMENT AND SIGNALING DEPENDENCIES DRIVING DIFFUSE MIDLINE GLIOMA TUMOR INITIATION, PROGRESSION, AND RESISTANCE: A COMPREHENSIVE APPROACH LEVERAGING BULK MULTIOMICS DECONVOLUTION AND SINGLE-CELL OMICS VALIDATION
Patel, Palak, Ryall, Scott, Kukreja, Bharti, Turinski, Andrei, Siddaway, Robert, Brudno, Michael, Ramani, Arun, Pajovic, Sanja, Kalish, Brian, Hawkins, Cynthia
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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Journal Article
Abstract 1165: Complementary diagnostics for precision targeting of cellular pathways
Siddaway, Robert, Nobre, Liana, Johnson, Monique, Milos, Scott, Ryall, Scott, Sheth, Javal, Tabori, Uri, Hawkins, Cynthia
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas
Lassaletta, Alvaro, Zapotocky, Michal, Mistry, Matthew, Ramaswamy, Vijay, Honnorat, Marion, Krishnatry, Rahul, Guerreiro Stucklin, Ana, Zhukova, Nataliya, Arnoldo, Anthony, Ryall, Scott, Ling, Catriona, McKeown, Tara, Loukides, Jim, Cruz, Ofelia, de Torres, Carmen, Ho, Cheng-Ying, Packer, Roger J, Tatevossian, Ruth, Qaddoumi, Ibrahim, Harreld, Julie H, Dalton, James D, Mulcahy-Levy, Jean, Foreman, Nicholas, Karajannis, Matthias A, Wang, Shiyang, Snuderl, Matija, Nageswara Rao, Amulya, Giannini, Caterina, Kieran, Mark, Ligon, Keith L, Garre, Maria Luisa, Nozza, Paolo, Mascelli, Samantha, Raso, Alessandro, Mueller, Sabine, Nicolaides, Theodore, Silva, Karen, Perbet, Romain, Vasiljevic, Alexandre, Faure Conter, Cécile, Frappaz, Didier, Leary, Sarah, Crane, Courtney, Chan, Aden, Ng, Ho-Keung, Shi, Zhi-Feng, Mao, Ying, Finch, Elizabeth, Eisenstat, David, Wilson, Bev, Carret, Anne Sophie, Hauser, Peter, Sumerauer, David, Krskova, Lenka, Larouche, Valerie, Fleming, Adam, Zelcer, Shayna, Jabado, Nada, Rutka, James T, Dirks, Peter, Taylor, Michael D, Chen, Shiyi, Bartels, Ute, Huang, Annie, Ellison, David W, Bouffet, Eric, Hawkins, Cynthia, Tabori, Uri
Published in Journal of clinical oncology (01.09.2017)
Published in Journal of clinical oncology (01.09.2017)
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Journal Article
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
Buczkowicz, Pawel, Hoeman, Christine, Rakopoulos, Patricia, Pajovic, Sanja, Letourneau, Louis, Dzamba, Misko, Morrison, Andrew, Lewis, Peter, Bouffet, Eric, Bartels, Ute, Zuccaro, Jennifer, Agnihotri, Sameer, Ryall, Scott, Barszczyk, Mark, Chornenkyy, Yevgen, Bourgey, Mathieu, Bourque, Guillaume, Montpetit, Alexandre, Cordero, Francisco, Castelo-Branco, Pedro, Mangerel, Joshua, Tabori, Uri, Ho, King Ching, Huang, Annie, Taylor, Kathryn R, Mackay, Alan, Bendel, Anne E, Nazarian, Javad, Fangusaro, Jason R, Karajannis, Matthias A, Zagzag, David, Foreman, Nicholas K, Donson, Andrew, Hegert, Julia V, Smith, Amy, Chan, Jennifer, Lafay-Cousin, Lucy, Dunn, Sandra, Hukin, Juliette, Dunham, Chris, Scheinemann, Katrin, Michaud, Jean, Zelcer, Shayna, Ramsay, David, Cain, Jason, Brennan, Cameron, Souweidane, Mark M, Jones, Chris, Allis, C David, Brudno, Michael, Becher, Oren, Hawkins, Cynthia
Published in Nature genetics (01.05.2014)
Published in Nature genetics (01.05.2014)
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Journal Article
Abstract A35: From map to model: Genetic evolution of diffuse intrinsic pontine glioma provides the framework for accurate tumor modeling
Lubanszky, Evan, Ryall, Scott, Siddaway, Robert, Kim, Byunjin, Bridge, Taylor, Pajovic, Sanja, Hawkins, Cynthia
Published in Cancer research (Chicago, Ill.) (01.06.2020)
Published in Cancer research (Chicago, Ill.) (01.06.2020)
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Journal Article
Abstract A09: Cerebrospinal fluid (CSF) as a source of ctDNA for diagnosis and monitoring of pediatric patients with midline diffuse gliomas
Nobre, Liana, Siddaway, Robert, Johnson, Monique, Ryall, Scott, Zapotocky, Michal, Bennet, Julie, Tabori, Uri, Hawkins, Cynthia
Published in Clinical cancer research (01.06.2020)
Published in Clinical cancer research (01.06.2020)
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Journal Article
IMMU-09. IMMUNOLOGICAL CHARACTERIZATION OF PEDIATRIC BRAIN TUMORS HAS CLINICAL IMPLICATIONS FOR PATIENT MANAGEMENT AND PROGNOSIS
Levine, Adrian, Nobre, Liana, Milos, Scott, Das, Anirban, Johnson, Monique, Laxer, Ben, Ryall, Scott, Siddaway, Robert, Tabori, Uri, Hawkins, Cynthia
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
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