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Targeting a ceramide double bond improves insulin resistance and hepatic steatosis
Chaurasia, Bhagirath, Tippetts, Trevor S., Monibas, Rafael Mayoral, Liu, Jinqi, Li, Ying, Wang, Liping, Wilkerson, Joseph L., Sweeney, C. Rufus, Pereira, Renato Felipe, Sumida, Doris Hissako, Maschek, J. Alan, Cox, James E., Kaddai, Vincent, Lancaster, Graeme Iain, Siddique, Monowarul Mobin, Poss, Annelise, Pearson, Mackenzie, Satapati, Santhosh, Zhou, Heather, McLaren, David G., Previs, Stephen F., Chen, Ying, Qian, Ying, Petrov, Aleksandr, Wu, Margaret, Shen, Xiaolan, Yao, Jun, Nunes, Christian N., Howard, Andrew D., Wang, Liangsu, Erion, Mark D., Rutter, Jared, Holland, William L., Kelley, David E., Summers, Scott A.
Published in Science (American Association for the Advancement of Science) (26.07.2019)
Published in Science (American Association for the Advancement of Science) (26.07.2019)
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Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport
Yang, Chendong, Ko, Bookyung, Hensley, Christopher T., Jiang, Lei, Wasti, Ajla T., Kim, Jiyeon, Sudderth, Jessica, Calvaruso, Maria Antonietta, Lumata, Lloyd, Mitsche, Matthew, Rutter, Jared, Merritt, Matthew E., DeBerardinis, Ralph J.
Published in Molecular cell (06.11.2014)
Published in Molecular cell (06.11.2014)
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The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
Cluntun, Ahmad A., Badolia, Rachit, Lettlova, Sandra, Parnell, K. Mark, Shankar, Thirupura S., Diakos, Nikolaos A., Olson, Kristofor A., Taleb, Iosif, Tatum, Sean M., Berg, Jordan A., Cunningham, Corey N., Van Ry, Tyler, Bott, Alex J., Krokidi, Aspasia Thodou, Fogarty, Sarah, Skedros, Sophia, Swiatek, Wojciech I., Yu, Xuejing, Luo, Bai, Merx, Shannon, Navankasattusas, Sutip, Cox, James E., Ducker, Gregory S., Holland, William L., McKellar, Stephen H., Rutter, Jared, Drakos, Stavros G.
Published in Cell metabolism (02.03.2021)
Published in Cell metabolism (02.03.2021)
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Lactate dehydrogenase activity drives hair follicle stem cell activation
Flores, Aimee, Schell, John, Krall, Abigail S., Jelinek, David, Miranda, Matilde, Grigorian, Melina, Braas, Daniel, White, Andrew C., Zhou, Jessica L., Graham, Nicholas A., Graeber, Thomas, Seth, Pankaj, Evseenko, Denis, Coller, Hilary A., Rutter, Jared, Christofk, Heather R., Lowry, William E.
Published in Nature cell biology (01.09.2017)
Published in Nature cell biology (01.09.2017)
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Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis
Simcox, Judith, Geoghegan, Gisela, Maschek, John Alan, Bensard, Claire L., Pasquali, Marzia, Miao, Ren, Lee, Sanghoon, Jiang, Lei, Huck, Ian, Kershaw, Erin E., Donato, Anthony J., Apte, Udayan, Longo, Nicola, Rutter, Jared, Schreiber, Renate, Zechner, Rudolf, Cox, James, Villanueva, Claudio J.
Published in Cell metabolism (05.09.2017)
Published in Cell metabolism (05.09.2017)
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Impact of Mitochondrial Fatty Acid Synthesis on Mitochondrial Biogenesis
Nowinski, Sara M., Van Vranken, Jonathan G., Dove, Katja K., Rutter, Jared
Published in Current biology (22.10.2018)
Published in Current biology (22.10.2018)
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A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans
Bricker, Daniel K., Taylor, Eric B., Schell, John C., Orsak, Thomas, Boutron, Audrey, Chen, Yu-Chan, Cox, James E., Cardon, Caleb M., Van Vranken, Jonathan G., Dephoure, Noah, Redin, Claire, Boudina, Sihem, Gygi, Steven P., Brivet, Michèle, Thummel, Carl S., Rutter, Jared
Published in Science (American Association for the Advancement of Science) (06.07.2012)
Published in Science (American Association for the Advancement of Science) (06.07.2012)
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A Role for the Mitochondrial Pyruvate Carrier as a Repressor of the Warburg Effect and Colon Cancer Cell Growth
Schell, John C., Olson, Kristofor A., Jiang, Lei, Hawkins, Amy J., Van Vranken, Jonathan G., Xie, Jianxin, Egnatchik, Robert A., Earl, Espen G., DeBerardinis, Ralph J., Rutter, Jared
Published in Molecular cell (06.11.2014)
Published in Molecular cell (06.11.2014)
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Maestro of the SereNADe: SLC25A51 Orchestrates Mitochondrial NAD
Ouyang, Yeyun, Bott, Alex J., Rutter, Jared
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.05.2021)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.05.2021)
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Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase
Hicks, Kevin G., Cluntun, Ahmad A., Schubert, Heidi L., Hackett, Sean R., Berg, Jordan A., Leonard, Paul G., Ajalla Aleixo, Mariana A., Zhou, Youjia, Bott, Alex J., Salvatore, Sonia R., Chang, Fei, Blevins, Aubrie, Barta, Paige, Tilley, Samantha, Leifer, Aaron, Guzman, Andrea, Arok, Ajak, Fogarty, Sarah, Winter, Jacob M., Ahn, Hee-Chul, Allen, Karen N., Block, Samuel, Cardoso, Iara A., Ding, Jianping, Dreveny, Ingrid, Gasper, William C., Ho, Quinn, Matsuura, Atsushi, Palladino, Michael J., Prajapati, Sabin, Sun, Pengkai, Tittmann, Kai, Tolan, Dean R., Unterlass, Judith, VanDemark, Andrew P., Vander Heiden, Matthew G., Webb, Bradley A., Yun, Cai-Hong, Zhao, Pengkai, Wang, Bei, Schopfer, Francisco J., Hill, Christopher P., Nonato, Maria Cristina, Muller, Florian L., Cox, James E., Rutter, Jared
Published in SCIENCE (10.03.2023)
Published in SCIENCE (10.03.2023)
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Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier
Bensard, Claire L., Wisidagama, Dona R., Olson, Kristofor A., Berg, Jordan A., Krah, Nathan M., Schell, John C., Nowinski, Sara M., Fogarty, Sarah, Bott, Alex J., Wei, Peng, Dove, Katja K., Tanner, Jason M., Panic, Vanja, Cluntun, Ahmad, Lettlova, Sandra, Earl, Christian S., Namnath, David F., Vázquez-Arreguín, Karina, Villanueva, Claudio J., Tantin, Dean, Murtaugh, L. Charles, Evason, Kimberley J., Ducker, Gregory S., Thummel, Carl S., Rutter, Jared
Published in Cell metabolism (04.02.2020)
Published in Cell metabolism (04.02.2020)
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Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins
Chen, Yu-Chan, Umanah, George K E, Dephoure, Noah, Andrabi, Shaida A, Gygi, Steven P, Dawson, Ted M, Dawson, Valina L, Rutter, Jared
Published in The EMBO journal (17.07.2014)
Published in The EMBO journal (17.07.2014)
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Vms1p is a release factor for the ribosome-associated quality control complex
Zurita Rendón, Olga, Fredrickson, Eric K., Howard, Conor J., Van Vranken, Jonathan, Fogarty, Sarah, Tolley, Neal D., Kalia, Raghav, Osuna, Beatriz A., Shen, Peter S., Hill, Christopher P., Frost, Adam, Rutter, Jared
Published in Nature communications (06.06.2018)
Published in Nature communications (06.06.2018)
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Transferred mitochondria accumulate reactive oxygen species, promoting proliferation
Kidwell, Chelsea U, Casalini, Joseph R, Pradeep, Soorya, Scherer, Sandra D, Greiner, Daniel, Bayik, Defne, Watson, Dionysios C, Olson, Gregory S, Lathia, Justin D, Johnson, Jarrod S, Rutter, Jared, Welm, Alana L, Zangle, Thomas A, Roh-Johnson, Minna
Published in eLife (06.03.2023)
Published in eLife (06.03.2023)
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SDH5, a Gene Required for Flavination of Succinate Dehydrogenase, Is Mutated in Paraganglioma
Hao, Huai-Xiang, Khalimonchuk, Oleh, Schraders, Margit, Dephoure, Noah, Bayley, Jean-Pierre, Kunst, Henricus, Devilee, Peter, Cremers, Cor W.R.J, Schiffman, Joshua D, Bentz, Brandon G, Gygi, Steven P, Winge, Dennis R, Kremer, Hannie, Rutter, Jared
Published in Science (American Association for the Advancement of Science) (28.08.2009)
Published in Science (American Association for the Advancement of Science) (28.08.2009)
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