In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma
Karreth, Florian A., Tay, Yvonne, Perna, Daniele, Ala, Ugo, Tan, Shen Mynn, Rust, Alistair G., DeNicola, Gina, Webster, Kaitlyn A., Weiss, Dror, Perez-Mancera, Pedro A., Krauthammer, Michael, Halaban, Ruth, Provero, Paolo, Adams, David J., Tuveson, David A., Pandolfi, Pier Paolo
Published in Cell (14.10.2011)
Published in Cell (14.10.2011)
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Journal Article
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer
Westcott, Peter M. K., Halliwill, Kyle D., To, Minh D., Rashid, Mamunur, Rust, Alistair G., Keane, Thomas M., Delrosario, Reyno, Jen, Kuang-Yu, Gurley, Kay E., Kemp, Christopher J., Fredlund, Erik, Quigley, David A., Adams, David J., Balmain, Allan
Published in Nature (London) (22.01.2015)
Published in Nature (London) (22.01.2015)
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Journal Article
Capture Hi-C identifies putative target genes at 33 breast cancer risk loci
Baxter, Joseph S., Leavy, Olivia C., Dryden, Nicola H., Maguire, Sarah, Johnson, Nichola, Fedele, Vita, Simigdala, Nikiana, Martin, Lesley-Ann, Andrews, Simon, Wingett, Steven W., Assiotis, Ioannis, Fenwick, Kerry, Chauhan, Ritika, Rust, Alistair G., Orr, Nick, Dudbridge, Frank, Haider, Syed, Fletcher, Olivia
Published in Nature communications (12.03.2018)
Published in Nature communications (12.03.2018)
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Journal Article
BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model
Perna, Daniele, Karreth, Florian A., Rust, Alistair G., Perez-Mancera, Pedro A., Rashid, Mamunur, Iorio, Francesco, Alifrangis, Constantine, Arends, Mark J., Bosenberg, Marcus W., Bollag, Gideon, Tuveson, David A., Adams, David J.
Published in Proceedings of the National Academy of Sciences - PNAS (10.02.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (10.02.2015)
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Journal Article
Chromatin landscapes of retroviral and transposon integration profiles
de Jong, Johann, Akhtar, Waseem, Badhai, Jitendra, Rust, Alistair G, Rad, Roland, Hilkens, John, Berns, Anton, van Lohuizen, Maarten, Wessels, Lodewyk F A, de Ridder, Jeroen
Published in PLoS genetics (01.04.2014)
Published in PLoS genetics (01.04.2014)
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Journal Article
Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma
Mann, Karen M., Ward, Jerrold M., Yew, Christopher Chin Kuan, Kovochich, Anne, Dawson, David W., Black, Michael A., Brett, Benjamin T., Sheetz, Todd E., Dupuy, Adam J., Chang, David K., Biankin, Andrew V., Waddell, Nicola, Kassahn, Karin S., Grimmond, Sean M., Rust, Alistair G., Adams, David J., Jenkins, Nancy A., Copeland, Neal G.
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (17.04.2012)
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Journal Article
Inactivating CUX1 mutations promote tumorigenesis
Wong, Chi C, Martincorena, Inigo, Rust, Alistair G, Rashid, Mamunur, Alifrangis, Constantine, Alexandrov, Ludmil B, Tiffen, Jessamy C, Kober, Christina, Green, Anthony R, Massie, Charles E, Nangalia, Jyoti, Lempidaki, Stella, Döhner, Hartmut, Döhner, Konstanze, Bray, Sarah J, McDermott, Ultan, Papaemmanuil, Elli, Campbell, Peter J, Adams, David J
Published in Nature genetics (01.01.2014)
Published in Nature genetics (01.01.2014)
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Journal Article
Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development
Takeda, Haruna, Rust, Alistair G., Ward, Jerrold M., Yew, Christopher Chin Kuan, Jenkins, Nancy A., Copeland, Neal G.
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2016)
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Journal Article
PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia
Dang, Jinjun, Wei, Lei, de Ridder, Jeroen, Su, Xiaoping, Rust, Alistair G., Roberts, Kathryn G., Payne-Turner, Debbie, Cheng, Jinjun, Ma, Jing, Qu, Chunxu, Wu, Gang, Song, Guangchun, Huether, Robert G., Schulman, Brenda, Janke, Laura, Zhang, Jinghui, Downing, James R., van der Weyden, Louise, Adams, David J., Mullighan, Charles G.
Published in Blood (04.06.2015)
Published in Blood (04.06.2015)
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Journal Article
Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes
Rashid, Mamunur, Fischer, Andrej, Wilson, Cathy H, Tiffen, Jessamy, Rust, Alistair G, Stevens, Philip, Idziaszczyk, Shelley, Maynard, Julie, Williams, Geraint T, Mustonen, Ville, Sampson, Julian R, Adams, David J
Published in The Journal of pathology (01.01.2016)
Published in The Journal of pathology (01.01.2016)
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Journal Article
Identification of FoxR2 as an Oncogene in Medulloblastoma
KOSO, Hideto, TSUHAKO, Asano, LYONS, Eli, WARD, Jerrold M, RUST, Alistair G, ADAMS, David J, JENKINS, Nancy A, COPELAND, Neal G, WATANABE, Sumiko
Published in Cancer research (Chicago, Ill.) (15.04.2014)
Published in Cancer research (Chicago, Ill.) (15.04.2014)
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Journal Article
Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics
Ramsey, Stephen A, Klemm, Sandy L, Zak, Daniel E, Kennedy, Kathleen A, Thorsson, Vesteinn, Li, Bin, Gilchrist, Mark, Gold, Elizabeth S, Johnson, Carrie D, Litvak, Vladimir, Navarro, Garnet, Roach, Jared C, Rosenberger, Carrie M, Rust, Alistair G, Yudkovsky, Natalya, Aderem, Alan, Shmulevich, Ilya
Published in PLoS computational biology (21.03.2008)
Published in PLoS computational biology (21.03.2008)
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Journal Article
Sleeping Beauty mutagenesis in a mouse medulloblastoma model defines networks that discriminate between human molecular subgroups
Genovesi, Laura A, Ng, Ching Ging, Davis, Melissa J, Remke, Marc, Taylor, Michael D, Adams, David J, Rust, Alistair G, Ward, Jerrold M, Ban, Kenneth H, Jenkins, Nancy A, Copeland, Neal G, Wainwright, Brandon J
Published in Proceedings of the National Academy of Sciences - PNAS (12.11.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (12.11.2013)
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Journal Article
Transposon mutagenesis identifies genes that transform neural stem cells into glioma-initiating cells
Koso, Hideto, Takeda, Haruna, Yew, Christopher Chin Kuan, Ward, Jerrold M, Nariai, Naoki, Ueno, Kazuko, Nagasaki, Masao, Watanabe, Sumiko, Rust, Alistair G, Adams, David J, Copeland, Neal G, Jenkins, Nancy A
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2012)
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Journal Article
A Data Integration Methodology for Systems Biology
Daehee Hwang, Rust, Alistair G., Stephen Ramsey, Smith, Jennifer J., Deena M. Leslie, Weston, Andrea D., Pedro de Atauri, Aitchison, John D., Hood, Leroy, Siegel, Andrew F., Bolouri, Hamid
Published in Proceedings of the National Academy of Sciences - PNAS (29.11.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (29.11.2005)
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Journal Article
Modeling the evolution of ETV6-RUNX1–induced B-cell precursor acute lymphoblastic leukemia in mice
van der Weyden, Louise, Giotopoulos, George, Rust, Alistair G., Matheson, Louise S., van Delft, Frederik W., Kong, Jun, Corcoran, Anne E., Greaves, Mel F., Mullighan, Charles G., Huntly, Brian J., Adams, David J.
Published in Blood (28.07.2011)
Published in Blood (28.07.2011)
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Journal Article
Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1
van der Weyden, Louise, Arends, Mark J, Rust, Alistair G, Poulogiannis, George, McIntyre, Rebecca E, Adams, David J
Published in Molecular cancer (03.05.2012)
Published in Molecular cancer (03.05.2012)
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Journal Article
A Data Integration Methodology for Systems Biology: Experimental Verification
Daehee Hwang, Smith, Jennifer J., Deena M. Leslie, Weston, Andrea D., Rust, Alistair G., Stephen Ramsey, Pedro de Atauri, Siegel, Andrew F., Bolouri, Hamid, Aitchison, John D., Hood, Leroy
Published in Proceedings of the National Academy of Sciences - PNAS (29.11.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (29.11.2005)
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Journal Article
Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis
Huser, Camille A, Gilroy, Kathryn L, de Ridder, Jeroen, Kilbey, Anna, Borland, Gillian, Mackay, Nancy, Jenkins, Alma, Bell, Margaret, Herzyk, Pawel, van der Weyden, Louise, Adams, David J, Rust, Alistair G, Cameron, Ewan, Neil, James C
Published in PLoS genetics (01.02.2014)
Published in PLoS genetics (01.02.2014)
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Journal Article