3[4-[1-(6-Fluorobenzo[b]thiophen-3-yl)-4-piperazinyl]butyl]-2,5,5-trimethyl-4-thiazolidinone: a new atypical antipsychotic agent for the treatment of schizophrenia
Hrib, Nicholas J, Jurcak, John G, Bregna, Deborah E, Dunn, Robert W, Geyer, Harry M, Hartman, Harold B, Roehr, Joachim E, Rogers, Kendra L, Rush, Douglas K
Published in Journal of medicinal chemistry (01.07.1992)
Published in Journal of medicinal chemistry (01.07.1992)
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Journal Article
Synthesis and Evaluation of 5-Amino-5,6,7,8-tetrahydroquinolinones as Potential Agents for the Treatment of Alzheimer's Disease
Fink, David M, Bores, Gina M, Effland, Richard C, Huger, Francis P, Kurys, Barbara E, Rush, Douglas K, Selk, David E
Published in Journal of medicinal chemistry (01.09.1995)
Published in Journal of medicinal chemistry (01.09.1995)
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Journal Article
Synthesis, Resolution, and SAR of (.+-.)-2-Amino-N-methyl-.alpha.-(3-methyl-2-thienyl)benzeneethanamine and Related Analogs as Noncompetitive NMDA Antagonists with Neuroprotective Properties
Martin, Lawrence L, Lee, George E, Lee, Thomas B. K, Rush, Douglas K, Wilmot, Carole A, Paulus, Erich, Elben, Ulrich, Grome, John J, Porsche-Wiebking, Elena
Published in Journal of medicinal chemistry (01.09.1994)
Published in Journal of medicinal chemistry (01.09.1994)
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Journal Article
Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine
G M Bores, F P Huger, W Petko, A E Mutlib, F Camacho, D K Rush, D E Selk, V Wolf, R W Kosley, Jr, L Davis, H M Vargas
Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1996)
Journal Article
Pharmacological activity and safety profile of P10358, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease
Smith, C P, Bores, G M, Petko, W, Li, M, Selk, D E, Rush, D K, Camacho, F, Winslow, J T, Fishkin, R, Cunningham, D M, Brooks, K M, Roehr, J, Hartman, H B, Davis, L, Vargas, H M
Published in The Journal of pharmacology and experimental therapeutics (01.02.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.1997)
Journal Article
Synthesis and preliminary structure-activity relationships of 1-[(3-fluoro-4-pyridinyl)amino]-3-methyl-1H-indol-5-yl methyl carbamate (P10358), a novel acetylcholinesterase inhibitor
Martin, Lawrence L., Davis, Larry, Klein, Joseph T., Nemoto, Peter, Olsen, Gordon E., Bores, Gina M., Camacho, Fernando, Petko, Wayne W., Rush, Douglas K., Selk, David, Smith, Craig P., Vargas, Hugo M., Winslow, James T., Effland, Richard C., Fink, David M.
Published in Bioorganic & medicinal chemistry letters (21.01.1997)
Published in Bioorganic & medicinal chemistry letters (21.01.1997)
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Journal Article
Pharmacological Activity and Safety Profile of P10358, a Novel, Orally Active Acetylcholinesterase Inhibitor for Alzheimerâs Disease
Craig P. Smith, Gina M. Bores, Wayne Petko, Mary Li, David E. Selk, Douglas K. Rush, Fernando Camacho, James T. Winslow, Rod Fishkin, Dana M. Cunningham, Karen M. Brooks, Joachim Roehr, Harold B. Hartman, Larry Davis, Hugo M. Vargas
Published in The Journal of pharmacology and experimental therapeutics (01.02.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.1997)
Journal Article
Synthesis and biological activity of putative mono-hydroxylated metabolites of velnacrine
Shutske, Gregory M., Bores, Gina M., Bradshaw, Katherine C., Huger, Francis P., Kapples, Kevin J., Larsen, Raymond D., Rush, Douglas K., Tomer, John D.
Published in Bioorganic & medicinal chemistry letters (1992)
Published in Bioorganic & medicinal chemistry letters (1992)
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Journal Article
Therapy for helpless monkeys
Rush, Douglas K., Mineka, Susan, Suomi, Stephen J.
Published in Behaviour research and therapy (1983)
Published in Behaviour research and therapy (1983)
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Journal Article