Broad-spectrum antiviral activity of PNU-183792, a 4-oxo-dihydroquinoline, against human and animal herpesviruses
Brideau, Roger J., Knechtel, Mary L., Huang, Audris, Vaillancourt, Valerie A., Vera, Ellen E., Oien, Nancee L., Hopkins, Todd A., Wieber, Janet L., Wilkinson, Karen F., Rush, Bob D., Schwende, Francis J., Wathen, Michael W.
Published in Antiviral research (01.04.2002)
Published in Antiviral research (01.04.2002)
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7-Oxo-4,7-dihydrothieno[3,2- b]pyridine-6-carboxamides: Synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase
Larsen, Scott D., Zhang, Zhijun, DiPaolo, Brian A., Manninen, Peter R., Rohrer, Douglas C., Hageman, Michael J., Hopkins, Todd A., Knechtel, Mary L., Oien, Nancee L., Rush, Bob D., Schwende, Francis J., Stefanski, Kevin J., Wieber, Janet L., Wilkinson, Karen F., Zamora, Kathyrn M., Wathen, Michael W., Brideau, Roger J.
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
Published in Bioorganic & medicinal chemistry letters (15.07.2007)
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Peptidomimetic HIV protease inhibitors: phosphate prodrugs with improved biological activities
Chong, Kong Teck, Ruwart, Mary J, Hinshaw, Roger R, Wilkinson, Karen F, Rush, Bob D, Yancey, Mark F, Strohbach, Joseph W, Thaisrivongs, Suvit
Published in Journal of medicinal chemistry (20.08.1993)
Published in Journal of medicinal chemistry (20.08.1993)
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Effects of alteration of hepatic microsomal enzyme activity on liver blood flow in the rat
Nies, A S, Wilkinson, G R, Rush, B D, Strother, J R, McDevitt, D G
Published in Biochemical pharmacology (01.09.1976)
Published in Biochemical pharmacology (01.09.1976)
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Structure-Based Design of HIV Protease Inhibitors: 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Non-peptidic Inhibitors
Thaisrivongs, Suvit, Tomich, Paul K, Watenpaugh, Keith D, Chong, Kong-Teck, Howe, W. Jeffrey, Yang, Chih-Ping, Strohbach, Joseph W, Turner, Steve R, McGrath, James P
Published in Journal of medicinal chemistry (01.09.1994)
Published in Journal of medicinal chemistry (01.09.1994)
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Structure-Based Design of Nonpeptidic HIV Protease Inhibitors: The Sulfonamide-Substituted Cyclooctylpyranones
Skulnick, Harvey I, Johnson, Paul D, Aristoff, Paul A, Morris, Jeanette K, Lovasz, Kristine D, Howe, W. Jeffrey, Watenpaugh, Keith D, Janakiraman, Musiri N, Anderson, David J, Reischer, Robert J, Schwartz, Theresa M, Banitt, Lee S, Tomich, Paul K, Lynn, Janet C, Horng, Miao-Miao, Chong, Kong-Teck, Hinshaw, Roger R, Dolak, Lester A, Seest, Eric P, Schwende, Francis J, Rush, Bob D, Howard, Gina M, Toth, Lisa N, Wilkinson, Karen R, Kakuk, Thomas J, Johnson, Carol W, Cole, Serena L, Zaya, Renee M, Zipp, Gail L, Possert, Peggy L, Dalga, Robert J, Zhong, Wei-Zhu, Williams, Marta G, Romines, Karen R
Published in Journal of medicinal chemistry (28.03.1997)
Published in Journal of medicinal chemistry (28.03.1997)
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Cyclosporine metabolism by P450IIIA in rat enterocytes--another determinant of oral bioavailability?
Kolars, J C, Stetson, P L, Rush, B D, Ruwart, M J, Schmiedlin-Ren, P, Duell, E A, Voorhees, J J, Watkins, P B
Published in Transplantation (01.03.1992)
Published in Transplantation (01.03.1992)
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Use of Medium-Sized Cycloalkyl Rings To Enhance Secondary Binding: Discovery of a New Class of Human Immunodeficiency Virus (HIV) Protease Inhibitors
Romines, Karen R, Watenpaugh, Keith D, Tomich, Paul K, Howe, W. Jeffrey, Morris, Jeanette K, Lovasz, Kristine D, Mulichak, Anne M, Finzel, Barry C, Lynn, Janet C
Published in Journal of medicinal chemistry (01.05.1995)
Published in Journal of medicinal chemistry (01.05.1995)
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The integrated value of serum procollagen III peptide over time predicts hepatic hydroxyproline content and stainable collagen in a model of dietary cirrhosis in the rat
Ruwart, M J, Wilkinson, K F, Rush, B D, Vidmar, T J, Peters, K M, Henley, K S, Appelman, H D, Kim, K Y, Schuppan, D, Hahn, E G
Published in Hepatology (Baltimore, Md.) (01.11.1989)
Published in Hepatology (Baltimore, Md.) (01.11.1989)
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Desolvation energy: a major determinant of absorption, but not clearance, of peptides in rats
Karls, M S, Rush, B D, Wilkinson, K F, Vidmar, T J, Burton, P S, Ruwart, M J
Published in Pharmaceutical research (01.12.1991)
Published in Pharmaceutical research (01.12.1991)
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16,16-Dimethyl prostaglandin E2 delays collagen formation in nutritional injury in rat liver
Ruwart, M J, Rush, B D, Snyder, K F, Peters, K M, Appelman, H D, Henley, K S
Published in Hepatology (Baltimore, Md.) (01.01.1988)
Published in Hepatology (Baltimore, Md.) (01.01.1988)
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Evaluation of a vitamin-cloaking strategy for oligopeptide therapeutics: biotinylated HIV-1 protease inhibitors
Islam, I, Ng, K. Y, Chong, K. T, McQuade, T. J, Hui, J. O, Wilkinson, K. F, Rush, B. D, Ruwart, M. J, Borchardt, R. T, Fisher, J. F
Published in Journal of medicinal chemistry (01.01.1994)
Published in Journal of medicinal chemistry (01.01.1994)
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Development of activity assays for high-volume evaluation of human immunodeficiency virus (HIV) protease inhibitors in rat serum: results with ditekiren
Wilkinson, K F, Rush, B D, Sharma, S K, Evans, D B, Ruwart, M J, Friis, J M, Bohanon, M J, Tomich, P K
Published in Pharmaceutical research (01.04.1993)
Published in Pharmaceutical research (01.04.1993)
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Development of a sensitive activity assay for high-volume evaluation of human renin inhibitory peptides in rat serum: results with U-71,038
Ruwart, M J, Sharma, S K, Harris, D W, Lakings, D B, Rush, B D, Wilkinson, K F, Cornette, J C, Evans, D B, Friis, J M, Cook, K J
Published in Pharmaceutical research (01.04.1990)
Published in Pharmaceutical research (01.04.1990)
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