4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition
Nagy, Nadine, Gurevich, Irina, Kuipers, Hedwich F., Ruppert, Shannon M., Marshall, Payton L., Xie, Bryan J., Sun, Wenchao, Malkovskiy, Andrey V., Rajadas, Jayakumar, Grandoch, Maria, Fischer, Jens W., Frymoyer, Adam R., Kaber, Gernot, Bollyky, Paul L.
Published in The Journal of biological chemistry (10.05.2019)
Published in The Journal of biological chemistry (10.05.2019)
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Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma
Larrayoz, Marta, Garcia-Barchino, Maria J., Celay, Jon, Etxebeste, Amaia, Jimenez, Maddalen, Perez, Cristina, Ordoñez, Raquel, Cobaleda, Cesar, Botta, Cirino, Fresquet, Vicente, Roa, Sergio, Goicoechea, Ibai, Maia, Catarina, Lasaga, Miren, Chesi, Marta, Bergsagel, P. Leif, Larrayoz, Maria J., Calasanz, Maria J., Campos-Sanchez, Elena, Martinez-Cano, Jorge, Panizo, Carlos, Rodriguez-Otero, Paula, Vicent, Silvestre, Roncador, Giovanna, Gonzalez, Patricia, Takahashi, Satoru, Katz, Samuel G., Walensky, Loren D., Ruppert, Shannon M., Lasater, Elisabeth A., Amann, Maria, Lozano, Teresa, Llopiz, Diana, Sarobe, Pablo, Lasarte, Juan J., Planell, Nuria, Gomez-Cabrero, David, Kudryashova, Olga, Kurilovich, Anna, Revuelta, Maria V., Cerchietti, Leandro, Agirre, Xabier, San Miguel, Jesus, Paiva, Bruno, Prosper, Felipe, Martinez-Climent, Jose A.
Published in Nature medicine (01.03.2023)
Published in Nature medicine (01.03.2023)
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Journal Article
Weekly injection of IL-2 using an injectable hydrogel reduces autoimmune diabetes incidence in NOD mice
Nagy, Nadine, Kaber, Gernot, Kratochvil, Michael J., Kuipers, Hedwich F., Ruppert, Shannon M., Yadava, Koshika, Yang, Jason, Heilshorn, Sarah C., Long, S. Alice, Pugliese, Alberto, Bollyky, Paul L.
Published in Diabetologia (01.01.2021)
Published in Diabetologia (01.01.2021)
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Journal Article
JunD/AP-1-mediated gene expression promotes lymphocyte growth dependent on interleukin-7 signal transduction
Ruppert, Shannon M, Chehtane, Mounir, Zhang, Ge, Hu, Haiyan, Li, Xiaoman, Khaled, Annette R
Published in PloS one (23.02.2012)
Published in PloS one (23.02.2012)
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Journal Article
Modified High-Molecular-Weight Hyaluronan Promotes Allergen-Specific Immune Tolerance
Gebe, John A, Yadava, Koshika, Ruppert, Shannon M, Marshall, Payton, Hill, Paul, Falk, Ben A, Sweere, Johanna M, Han, Hongwei, Kaber, Gernot, Harten, Ingrid A, Medina, Carlos, Mikecz, Katalin, Ziegler, Steven F, Balaji, Swathi, Keswani, Sundeep G, Perez, Vinicio A de Jesus, Butte, Manish J, Nadeau, Kari, Altemeier, William A, Fanger, Neil, Bollyky, Paul L
Published in American journal of respiratory cell and molecular biology (01.01.2017)
Published in American journal of respiratory cell and molecular biology (01.01.2017)
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Journal Article
Phase I Study of Safety and Pharmacokinetics of RO7297089, an Anti-BCMA/CD16a Bispecific Antibody, in Patients with Relapsed, Refractory Multiple Myeloma
Plesner, Torben, Harrison, Simon J., Quach, Hang, Lee, Cindy, Bryant, Adam, Vangsted, Annette, Estell, Jane, Delforge, Michel, Offner, Fritz, Twomey, Patrick, Choeurng, Voleak, Li, Junyi, Hendricks, Robert, Ruppert, Shannon M., Sumiyoshi, Teiko, Miller, Karen, Cho, Eunpi, Schjesvold, Fredrik
Published in Clinical hematology international (01.03.2023)
Published in Clinical hematology international (01.03.2023)
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Journal Article
The major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes
Ruppert, Shannon M., Li, Wenqing, Zhang, Ge, Carlson, Adina L., Limaye, Arati, Durum, Scott K., Khaled, Annette R.
Published in Biochimica et biophysica acta (01.10.2012)
Published in Biochimica et biophysica acta (01.10.2012)
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Journal Article
The Immune Response to Chronic Pseudomonas aeruginosa Wound Infection in Immunocompetent Mice
Sweere, Johanna M, Ishak, Heather, Sunkari, Vivekananda, Bach, Michelle S, Manasherob, Robert, Yadava, Koshika, Ruppert, Shannon M, Sen, Chandan K, Balaji, Swathi, Keswani, Sundeep G, Secor, Patrick R, Bollyky, Paul L
Published in Advances in wound care (New Rochelle, N.Y.) (01.02.2020)
Published in Advances in wound care (New Rochelle, N.Y.) (01.02.2020)
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Journal Article
Case report: A persistently expanded T cell response in an exceptional responder to radiation and atezolizumab for metastatic non-small cell lung cancer
Coffey, David G., Xu, Yuexin, Towlerton, Andrea M. H., Kowanetz, Marcin, Hegde, Priti, Darwish, Martine, Yadav, Mahesh, Blanchette, Craig, Ruppert, Shannon M., Bertino, Sarah, Xu, Qikai, Ferretti, Andrew, Weinheimer, Adam, Hellmann, Matthew, Qin, Angel, Thomas, Dafydd, Warren, Edus H., Ramnath, Nithya
Published in Frontiers in immunology (09.09.2022)
Published in Frontiers in immunology (09.09.2022)
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Journal Article
Apoptosis-induced alkalinization by the Na+/H+ exchanger isoform 1 is mediated through phosphorylation of amino acids Ser726 and Ser729
Grenier, Amy L, Abu-ihweij, Khaled, Zhang, Ge, Ruppert, Shannon Moore, Boohaker, Rebecca, Slepkov, Emily R, Pridemore, Kathryn, Ren, Jian-Jian, Fliegel, Larry, Khaled, Annette R
Published in American Journal of Physiology: Cell Physiology (01.10.2008)
Published in American Journal of Physiology: Cell Physiology (01.10.2008)
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Journal Article
Biomarker Analysis of a Phase Ia/Ib Open-Label, Multicentre Study of Tiragolumab or Tiragolumab + Rituximab in Patients with Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (NHL)
Ruppert, Shannon, Cuchelkar, Vaikunth, Meng, Raymond, Cho, Eunpi, Lear, Sean, Wong, Cheryl Victoria, Raval, Aparna, Nouet, Yann
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
CO43923: A Platform Study Evaluating the Safety and Efficacy of Multiple Treatment Combinations in Patients with Multiple Myeloma
Sheikh, Semira, Patil, Upen, Wehrman, Kristin, Sideri, Elissavet, Ruppert, Shannon M., Yu, Yanke, Yan, Mark, Bhatti, Jasdeep, Pogeza, Lydia, Nouet, Yann
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
P-270: GO41036: a Phase Ia/Ib open-label, multicenter study evaluating the safety and pharmacokinetics of tiragolumab in combination with atezolizumab and daratumumab in patients with R/R MM
Ruppert, Shannon M., Cuchelkar, Vaikunth, Soman, Anisha, Johnson, Diantha, Nouet, Yann
Published in Clinical lymphoma, myeloma and leukemia (01.08.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.08.2022)
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Journal Article
OA-50 Pharmacodynamic effects of tiragolumab, as monotherapy and in combos with daratumumab and atezolizumab in patients with R/R MM: biomarker results from a phase 1a/1b trial
Ruppert, Shannon, Diaz, Giovanni, Lear, Sean, Hilz, Stephanie, Spranza, Brynn, Liechti, Thomas, Hamidi, Habib, Hendricks, Robert, Wong, Cheryl, Cuchelkar, Vaikunth, Soman, Anisha, Santos, Cedric Dos, Nouet, Yann
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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Journal Article
Bim is a component of the endosomal-lysosomal interface in Interleukin-7 dependent T cells (57.10)
Khaled, Annette, Ruppert, Shannon, Carlson, Adina
Published in The Journal of immunology (1950) (01.04.2011)
Published in The Journal of immunology (1950) (01.04.2011)
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Journal Article
OAB-033: Pre-clinical models of genetically heterogeneous multiple myeloma reveal mechanisms of immune escape and predict clinical immunotherapy outcomes
Larrayoz, Marta, Garcia-Barchino, Maria J., Celay, Jon, Etxebeste, Amaia, Jimenez, Maddalen, Perez, Cristina, Ordoñez, Raquel, Cobaleda, Cesar, Chesi, Marta, Bergsagel, Leif, Rodríguez-Otero, Paula, Takahashi, Satoru, Katz, Samuel G., Walensky, Loren D., Ruppert, Shannon M., Lasater, Elisabeth A., Amann, Maria, Lasarte, Juan J., Kurilovich, Anna, Cerchietti, Leandro, Agirre, Xabier, San-Miguel, Jesus, Paiva, Bruno, Prosper, Felipe, Martinez-Climent, Jose A.
Published in Clinical lymphoma, myeloma and leukemia (01.08.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.08.2022)
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Journal Article
Apoptotic alkalinization induced by loss of a growth signal is mediated by phosphorylation of the Na+/H+ Exchanger isoform 1 at Ser726 and Ser729 (35.12)
Khaled, Annette R, Zhang, Ge, Ruppert, Shannon, Boohaker, Rebecca, Khaled, Amr S
Published in The Journal of immunology (1950) (01.04.2009)
Published in The Journal of immunology (1950) (01.04.2009)
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Journal Article
Apoptosis-induced alkalinization by the Na+/H+ exchanger isoform 1 is mediated through phosphorylation of amino acids Ser726 and Ser729
GRENIER, Amy L, ABU-IHWEIJ, Khaled, GE ZHANG, MOORE RUPPERT, Shannon, BOOHAKER, Rebecca, SLEPKOV, Emily R, PRIDEMORE, Kathryn, REN, Jian-Jian, FLIEGEL, Larry, KHALED, Annette R
Published in American Journal of Physiology: Cell Physiology (2008)
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Published in American Journal of Physiology: Cell Physiology (2008)
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