Oxidation pattern of the anticancer drug ellipticine by hepatic microsomes - similarity between human and rat systems
Stiborová, M, Borek-Dohalská, L, Aimová, D, Kotrbová, V, Kukacková, K, Janouchová, K, Rupertová, M, Ryslavá, H, Hudecek, J, Frei, E
Published in General physiology and biophysics (01.09.2006)
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Published in General physiology and biophysics (01.09.2006)
Journal Article
The Anticancer Drug Ellipticine Forms Covalent DNA Adducts, Mediated by Human Cytochromes P450, through Metabolism to 13-Hydroxyellipticine and Ellipticine N 2-Oxide
Stiborová, Marie, Sejbal, Jan, Bořek-Dohalská, Lucie, Aimová, Dagmar, Poljaková, Jitka, Forsterová, Kristina, Rupertová, Martina, Wiesner, Jiří, Hudeček, Jiří, Wiessler, Manfred, Frei, Eva
Published in Cancer research (Chicago, Ill.) (15.11.2004)
Published in Cancer research (Chicago, Ill.) (15.11.2004)
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Journal Article
Formation and persistence of DNA adducts of anticancer drug ellipticine in rats
Stiborová, Marie, Rupertová, Martina, Aimová, Dagmar, Ryšlavá, Helena, Frei, Eva
Published in Toxicology (Amsterdam) (01.07.2007)
Published in Toxicology (Amsterdam) (01.07.2007)
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Journal Article
Rat Microsomes Activating the Anticancer Drug Ellipticine to Species Covalently Binding to Deoxyguanosine in DNA Are a Suitable Model Mimicking Ellipticine Bioactivation in Humans
Stiborová, Marie, Stiborová-Rupertová, Martina, Bořek-Dohalská, Lucie, Wiessler, Manfred, Frei, Eva
Published in Chemical research in toxicology (01.01.2003)
Published in Chemical research in toxicology (01.01.2003)
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Journal Article
DNA adduct formation by the anticancer drug ellipticine in rats determined by super(32)P postlabeling
Stiborova, M, Breuer, A, Aimova, D, Stiborova-Rupertova, M, Wiessler, M, Frei, E
Published in International journal of cancer (01.01.2003)
Published in International journal of cancer (01.01.2003)
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Journal Article