Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity
Hoves, Sabine, Ooi, Chia-Huey, Wolter, Carsten, Sade, Hadassah, Bissinger, Stefan, Schmittnaegel, Martina, Ast, Oliver, Giusti, Anna M, Wartha, Katharina, Runza, Valeria, Xu, Wei, Kienast, Yvonne, Cannarile, Michael A, Levitsky, Hyam, Romagnoli, Solange, De Palma, Michele, Rüttinger, Dominik, Ries, Carola H
Published in The Journal of experimental medicine (05.03.2018)
Published in The Journal of experimental medicine (05.03.2018)
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RG7386, a Novel Tetravalent FAP-DR5 Antibody, Effectively Triggers FAP-Dependent, Avidity-Driven DR5 Hyperclustering and Tumor Cell Apoptosis
Brünker, Peter, Wartha, Katharina, Friess, Thomas, Grau-Richards, Sandra, Waldhauer, Inja, Koller, Claudia Ferrara, Weiser, Barbara, Majety, Meher, Runza, Valeria, Niu, Huifeng, Packman, Kathryn, Feng, Ningping, Daouti, Sherif, Hosse, Ralf J, Mössner, Ekkehard, Weber, Thomas G, Herting, Frank, Scheuer, Werner, Sade, Hadassah, Shao, Cuiying, Liu, Bin, Wang, Peng, Xu, Gary, Vega-Harring, Suzana, Klein, Christian, Bosslet, Klaus, Umaña, Pablo
Published in Molecular cancer therapeutics (01.05.2016)
Published in Molecular cancer therapeutics (01.05.2016)
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Ficolins: Novel pattern recognition molecules of the innate immune response
Runza, Valeria L, Schwaeble, Wilhelm, Männel, Daniela N
Published in Immunobiology (1979) (01.01.2008)
Published in Immunobiology (1979) (01.01.2008)
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Targeting Tumor Cells with Anti-CD44 Antibody Triggers Macrophage-Mediated Immune Modulatory Effects in a Cancer Xenograft Model
Maisel, Daniela, Birzele, Fabian, Voss, Edgar, Nopora, Adam, Bader, Sabine, Friess, Thomas, Goller, Bernhard, Laifenfeld, Daphna, Weigand, Stefan, Runza, Valeria
Published in PloS one (27.07.2016)
Published in PloS one (27.07.2016)
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Reversion to an embryonic alternative splicing program enhances leukemia stem cell self-renewal
Holm, Frida, Hellqvist, Eva, Mason, Cayla N., Ali, Shawn A., Delos-Santos, Nathaniel, Barrett, Christian L., Chun, Hye-Jung, Minden, Mark D., Moore, Richard A., Marra, Marco A., Runza, Valeria, Frazer, Kelly A., Sadarangani, Anil, Jamieson, Catriona H. M.
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2015)
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End-to-end approach for the characterization and control of product-related impurities in T cell bispecific antibody preparations
Larivière, Laurent, Krüger, Julia Eva, von Hirschheydt, Thomas, Schlothauer, Tilman, Bray-French, Katharine, Bader, Martin, Runza, Valeria
Published in International journal of pharmaceutics: X (01.12.2023)
Published in International journal of pharmaceutics: X (01.12.2023)
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Immature mouse granulocytic myeloid cells are characterized by production of ficolin-B
Weber-Steffens, Dorothea, Hunold, Katja, Kürschner, Johanna, Martinez, Sonia Giraldez, Elumalai, Preetham, Schmidt, Dominic, Trevani, Analia, Runza, Valeria L., Männel, Daniela N.
Published in Molecular immunology (01.12.2013)
Published in Molecular immunology (01.12.2013)
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Functional analysis of mouse ficolin-B and detection in neutrophils
Hunold, Katja, Weber-Steffens, Dorothea, Runza, Valeria L, Jensenius, Jens C, Männel, Daniela N
Published in Immunobiology (1979) (01.10.2012)
Published in Immunobiology (1979) (01.10.2012)
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A drug development perspective on targeting tumor‐associated myeloid cells
Majety, Meher, Runza, Valeria, Lehmann, Christian, Hoves, Sabine, Ries, Carola H.
Published in The FEBS journal (01.02.2018)
Published in The FEBS journal (01.02.2018)
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Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy
Ries, Carola H., Cannarile, Michael A., Hoves, Sabine, Benz, Jörg, Wartha, Katharina, Runza, Valeria, Rey-Giraud, Flora, Pradel, Leon P., Feuerhake, Friedrich, Klaman, Irina, Jones, Tobin, Jucknischke, Ute, Scheiblich, Stefan, Kaluza, Klaus, Gorr, Ingo H., Walz, Antje, Abiraj, Keelara, Cassier, Philippe A., Sica, Antonio, Gomez-Roca, Carlos, de Visser, Karin E., Italiano, Antoine, Le Tourneau, Christophe, Delord, Jean-Pierre, Levitsky, Hyam, Blay, Jean-Yves, Rüttinger, Dominik
Published in Cancer cell (16.06.2014)
Published in Cancer cell (16.06.2014)
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T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells
Marigo, Ilaria, Zilio, Serena, Desantis, Giacomo, Mlecnik, Bernhard, Agnellini, Andrielly H.R., Ugel, Stefano, Sasso, Maria Stella, Qualls, Joseph E., Kratochvill, Franz, Zanovello, Paola, Molon, Barbara, Ries, Carola H., Runza, Valeria, Hoves, Sabine, Bilocq, Amélie M., Bindea, Gabriela, Mazza, Emilia M.C., Bicciato, Silvio, Galon, Jérôme, Murray, Peter J., Bronte, Vincenzo
Published in Cancer cell (12.09.2016)
Published in Cancer cell (12.09.2016)
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Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia
Vey, Norbert, Delaunay, Jacques, Martinelli, Giovanni, Fiedler, Walter, Raffoux, Emmanuel, Prebet, Thomas, Gomez-Roca, Carlos, Papayannidis, Cristina, Kebenko, Maxim, Paschka, Peter, Christen, Randolph, Guarin, Ernesto, Bröske, Ann-Marie, Baehner, Monika, Brewster, Michael, Walz, Antje-Christine, Michielin, Francesca, Runza, Valeria, Meresse, Valerie, Recher, Christian
Published in Oncotarget (31.05.2016)
Published in Oncotarget (31.05.2016)
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T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells
Marigo, Ilaria, Zilio, Serena, Desantis, Giacomo, Mlecnik, Bernhard, Agnellini, Andrielly H.R., Ugel, Stefano, Sasso, Maria Stella, Qualls, Joseph E., Kratochvill, Franz, Zanovello, Paola, Molon, Barbara, Ries, Carola H., Runza, Valeria, Hoves, Sabine, Bilocq, Amélie M., Bindea, Gabriela, Mazza, Emilia M.C., Bicciato, Silvio, Galon, Jérôme, Murray, Peter J., Bronte, Vincenzo
Published in Cancer cell (10.10.2016)
Published in Cancer cell (10.10.2016)
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CD44 Isoform Status Predicts Response to Treatment with Anti-CD44 Antibody in Cancer Patients
Birzele, Fabian, Voss, Edgar, Nopora, Adam, Honold, Konrad, Heil, Florian, Lohmann, Sabine, Verheul, Henk, Le Tourneau, Christophe, Delord, Jean-Pierre, van Herpen, Carla, Mahalingam, Devalingam, Coveler, Andrew L, Meresse, Valerie, Weigand, Stefan, Runza, Valeria, Cannarile, Michael
Published in Clinical cancer research (15.06.2015)
Published in Clinical cancer research (15.06.2015)
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이중특이적 항-CCL2 항체
SYDOW ANDERSEN JASMIN, BERTINETTI LAPATKI CRISTINA, KACPRZYK LUKASZ, GERTZ MICHAEL, GAN SIOK WAN, HO WEI SHIONG ADRIAN, GEORGES GUY, RUNZA VALERIA, LAM RUNYI ADELINE, FISCHER JENS, FENG SHU
Year of Publication 19.02.2024
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Year of Publication 19.02.2024
Patent
Abstract A59: A novel bispecific FAP-DR5 antibody inducing potent and tumor-specific death receptor 5 (DR5) activation by fibroblast activation protein (FAP) dependent crosslinking
Wartha, Katharina, Weiser, Barbara, Friess, Thomas, Majety, Meher, Runza, Valeria, Herting, Frank, Weber, Thomas, Scheuer, Werner, Harring, Suzana Vega, Sade, Hadassah, Niu, Huifeng
Published in Cancer research (Chicago, Ill.) (01.01.2015)
Published in Cancer research (Chicago, Ill.) (01.01.2015)
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Malignant Reprogramming of Progenitors into Leukemia Stem Cells Is Enhanced By Upregulation of CD44 Transcript Variant 3 in Malignant Microenvironments
Holm, Frida L, Hellqvist, Eva, Mason, Cayla N, Barrett, Christian L, Ali, Shawn, Chun, Hye-Jung, Marra, Marco A., Runza, Valeria, Frazer, Kelly A, Sadarangani, Anil, Jamieson, Catriona
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Abstract 4573: A novel bispecific Fap-Dr5 antibody inducing potent and tumor-specific death receptor 5 (Dr5) activation by fibroblast activation protein (Fap)-dependent crosslinking
Wartha, Katharina, Weiser, Barbara, Friess, Thomas, Majety, Meher, Runza, Valeria, Herting, Frank, Weber, Thomas, Scheuer, Werner, Harring, Suzana Vega, Sade, Hadassah, Niu, Huifeng, Bruenker, Peter
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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이중특이적 항-CCL2 항체
JORDAN GREGOR, MAJETY MEHER, GAN SIOK WAN, GERTZ MICHAEL, LAM RUNYI ADELINE, RUNZA VALERIA, FISCHER JENS, KETTENBERGER HUBERT, SCHLOTHAUER TILMAN, FENG SHU, JOCHNER ANTON, TIEFENTHALER GEORG, VIERT MARIA, HO WEI SHIONG ADRIAN, GEORGES GUY, SCHAEFER MARTIN, MOELLEKEN JOERG
Year of Publication 16.08.2022
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Year of Publication 16.08.2022
Patent