Serum-Free, Long-Term Cultures of Human Hepatocytes: Maintenance of Cell Morphology, Transcription Factors, and Liver-Specific Functions
Runge, Dieter, Runge, Dorothee M., Jäger, Dana, Lubecki, Kimberly A., Beer Stolz, Donna, Karathanasis, Sotirios, Kietzmann, Thomas, Strom, Stephen C., Jungermann, Kurt, Fleig, Wolfgang E., Michalopoulos, George K.
Published in Biochemical and biophysical research communications (05.03.2000)
Published in Biochemical and biophysical research communications (05.03.2000)
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Methoden zur Transportercharakterisierung in primären Hepatozyten
Keiser, Markus, Jia, Jia, Siegmund, Werner, Ullrich, Anett, Runge, Dieter
Published in Biospektrum (01.03.2015)
Published in Biospektrum (01.03.2015)
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Journal Article
Epidermal growth factor- and hepatocyte growth factor-receptor activity in serum-free cultures of human hepatocytes
RUNGE, D. M, RUNGE, D, DORKO, K, PISAROV, L. A, LECKEL, K, KOSTRUBSKY, V. E, THOMAS, D, STROM, S. C, MICHALOPOULOS, G. K
Published in Journal of hepatology (01.02.1999)
Published in Journal of hepatology (01.02.1999)
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Journal Article
Differential Expression and Distribution of Focal Adhesion and Cell Adhesion Molecules in Rat Hepatocyte Differentiation
Kim, Tae-Hyoung, Bowen, William C., Stolz, Donna B., Runge, Dieter, Mars, Wendy M., Michalopoulos, George K.
Published in Experimental cell research (10.10.1998)
Published in Experimental cell research (10.10.1998)
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Phenobarbital Suppresses Growth and Accelerates Restoration of Differentiation Markers of Primary Culture Rat Hepatocytes in the Chemically Defined Hepatocyte Growth Medium Containing Hepatocyte Growth Factor and Epidermal Growth Factor
Miyazaki, Masahiro, Mars, Wendy M, Runge, Dieter, Kim, Tae-Hyoung, Bowen, William C, Michalopoulos, George K
Published in Experimental cell research (15.06.1998)
Published in Experimental cell research (15.06.1998)
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HepaChip-MP - a twenty-four chamber microplate for a continuously perfused liver coculture model
Busche, Marius, Tomilova, Olena, Schütte, Julia, Werner, Simon, Beer, Meike, Groll, Nicola, Hagmeyer, Britta, Pawlak, Michael, Jones, Peter D, Schmees, Christian, Becker, Holger, Schnabel, Juliane, Gall, Karsten, Hemmler, Roland, Matz-Soja, Madlen, Damm, Georg, Beuck, Simon, Klaassen, Tobias, Moer, Jana, Ullrich, Anett, Runge, Dieter, Schenke-Layland, Katja, Gebhardt, Rolf, Stelzle, Martin
Published in Lab on a chip (11.08.2020)
Published in Lab on a chip (11.08.2020)
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Characterization of uptake and efflux transporters in fresh isolated and cryopreserved primary hepatocytes of different species by using radiolabeled substrates
Keiser, Markus, Ullrich, Anett, Jia, Jia, Patrzyk, Maciej, Busemann, Alexandra, Heidecke, Claus-Dieter, Siegmund, Werner, Runge, Dieter
Published in Toxicology letters (10.09.2014)
Published in Toxicology letters (10.09.2014)
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Induction of Cytochrome P450 (CYP)1A1, CYP1A2, and CYP3A4 but Not of CYP2C9, CYP2C19, Multidrug Resistance (MDR-1) and Multidrug Resistance Associated Protein (MRP-1) by Prototypical Inducers in Human Hepatocytes
Runge, Dieter, Köhler, Christoph, Kostrubsky, Vsevolod E., Jäger, Dana, Lehmann, Thomas, Runge, Dorothee M., May, Ursula, Stolz, Donna Beer, Strom, Stephen C., Fleig, Wolfgang E., Michalopoulos, George K.
Published in Biochemical and biophysical research communications (24.06.2000)
Published in Biochemical and biophysical research communications (24.06.2000)
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Long term cultures of primary human hepatocytes as an alternative to drug testing in animals
Ullrich, Anett, Stolz, Donna B, Ellis, Ewa C, Strom, Stephen C, Michalopoulos, George K, Hengstler, Jan G, Runge, Dieter
Published in ALTEX, alternatives to animal experimentation (2009)
Published in ALTEX, alternatives to animal experimentation (2009)
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Anticancer drug cis-4-hydroxy-L-proline: Correlation of preclinical toxicology with clinical parameters of liver function
Dickens, Heather, Ullrich, Anett, Runge, Dieter, Mueller, Berno, Olszewski, Ulrike, Hamilton, Gerhard
Published in Molecular medicine reports (01.07.2008)
Published in Molecular medicine reports (01.07.2008)
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Journal Article
STAT 1α/1β, STAT 3 and STAT 5: Expression and Association with c-MET and EGF-Receptor in Long-Term Cultures of Human Hepatocytes
Runge, Dorothee M., Runge, Dieter, Foth, Heidi, Strom, Stephen C., Michalopoulos, George K.
Published in Biochemical and biophysical research communications (19.11.1999)
Published in Biochemical and biophysical research communications (19.11.1999)
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Use of a standardised and validated long-term human hepatocyte culture system for repetitive analyses of drugs: repeated administrations of acetaminophen reduces albumin and urea secretion
Ullrich, Anett, Berg, Christine, Hengstler, Jan G, Runge, Dieter
Published in ALTEX, alternatives to animal experimentation (2007)
Published in ALTEX, alternatives to animal experimentation (2007)
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Journal Article
Negative protein 1, which is required for function of the chicken lysozyme gene silencer in conjunction with hormone receptors, is identical to the multivalent zinc finger repressor CTCF
Burcin, Mark, Arnold, Rüdiger, Lutz, Marcus, Kaiser, Burkhard, Runge, Dieter, Lottspeich, Friedrich, Filippova, Galina N., Lobanenkov, Victor V., Renkawitz, Rainer
Published in Molecular and Cellular Biology (01.03.1997)
Published in Molecular and Cellular Biology (01.03.1997)
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Journal Article
Recent Advances in Human Hepatocyte Culture Systems
Runge, Dieter, Michalopoulos, George K., Strom, Steven C., Runge, Dorothee M.
Published in Biochemical and biophysical research communications (21.07.2000)
Published in Biochemical and biophysical research communications (21.07.2000)
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Journal Article
In vitro system for the prediction of hepatotoxic effects in primary hepatocytes
Thedinga, Elke, Ullrich, Anett, Drechsler, Sabine, Niendorf, Ricarda, Kob, Axel, Runge, Dieter, Keuer, Andreas, Freund, Ingo, Lehmann, Mirko, Ehret, Ralf
Published in ALTEX, alternatives to animal experimentation (2007)
Published in ALTEX, alternatives to animal experimentation (2007)
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The expression of cell cycle related proteins in rat hepatocytes is distinct from human hepatocytes when cultured in serum-free media supplemented with HGF (hepatocyte growth factor) and EGF (epidermal growth factor)
Walldorf, Jens, Koehler, Christoph, Cai, Hongbo, Kleist, Sina, Runge, Dieter, Strom, Stephen, Fleig, Wolfgang E., Aurich, H.
Published in Journal of hepatology (01.04.2002)
Published in Journal of hepatology (01.04.2002)
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