Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics
McAleer, Christopher W, Long, Christopher J, Elbrecht, Daniel, Sasserath, Trevor, Bridges, L Richard, Rumsey, John W, Martin, Candace, Schnepper, Mark, Wang, Ying, Schuler, Franz, Roth, Adrian B, Funk, Christoph, Shuler, Michael L, Hickman, James J
Published in Science translational medicine (19.06.2019)
Published in Science translational medicine (19.06.2019)
Get more information
Journal Article
Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation
Slaughter, Victoria L, Rumsey, John W, Boone, Rachel, Malik, Duaa, Cai, Yunqing, Sriram, Narasimhan Narasimhan, Long, Christopher J, McAleer, Christopher W, Lambert, Stephen, Shuler, Michael L, Hickman, J J
Published in Scientific reports (23.06.2021)
Published in Scientific reports (23.06.2021)
Get full text
Journal Article
A functional hiPSC-cortical neuron differentiation and maturation model and its application to neurological disorders
Autar, Kaveena, Guo, Xiufang, Rumsey, John W., Long, Christopher J., Akanda, Nesar, Jackson, Max, Narasimhan, Narasimhan S., Caneus, Julbert, Morgan, Dave, Hickman, James J.
Published in Stem cell reports (11.01.2022)
Published in Stem cell reports (11.01.2022)
Get full text
Journal Article
Differential Monocyte Actuation in a Three‐Organ Functional Innate Immune System‐on‐a‐Chip
Sasserath, Trevor, Rumsey, John W., McAleer, Christopher W., Bridges, Lee Richard, Long, Christopher J., Elbrecht, Daniel, Schuler, Franz, Roth, Adrian, Bertinetti‐LaPatki, Christina, Shuler, Michael L., Hickman, James J.
Published in Advanced science (01.07.2020)
Published in Advanced science (01.07.2020)
Get full text
Journal Article
A Functional Human-on-a-Chip Autoimmune Disease Model of Myasthenia Gravis for Development of Therapeutics
Smith, Virginia M, Nguyen, Huan, Rumsey, John W, Long, Christopher J, Shuler, Michael L, Hickman, James J
Published in Frontiers in cell and developmental biology (22.11.2021)
Published in Frontiers in cell and developmental biology (22.11.2021)
Get full text
Journal Article
Classical Complement Pathway Inhibition in a “Human‐On‐A‐Chip” Model of Autoimmune Demyelinating Neuropathies
Rumsey, John W., Lorance, Case, Jackson, Max, Sasserath, Trevor, McAleer, Christopher W., Long, Christopher J., Goswami, Arindom, Russo, Melissa A., Raja, Shruti M., Gable, Karissa L., Emmett, Doug, Hobson‐Webb, Lisa D., Chopra, Manisha, Howard, James F., Guptill, Jeffrey T., Storek, Michael J., Alonso‐Alonso, Miguel, Atassi, Nazem, Panicker, Sandip, Parry, Graham, Hammond, Timothy, Hickman, James J.
Published in Advanced therapeutics (01.06.2022)
Published in Advanced therapeutics (01.06.2022)
Get full text
Journal Article
Functional myotube formation from adult rat satellite cells in a defined serum-free system
McAleer, Christopher W., Rumsey, John W., Stancescu, Maria, Hickman, James J.
Published in Biotechnology progress (01.07.2015)
Published in Biotechnology progress (01.07.2015)
Get full text
Journal Article
A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 and tau‐induced pathophysiological effects on long‐term potentiation
Caneus, Julbert, Akanda, Nesar, Rumsey, John W., Guo, Xiufang, Jackson, Max, Long, Christopher J., Sommerhage, Frank, Georgieva, Sanya, Kanaan, Nicholas M., Morgan, David, Hickman, James J.
Published in Alzheimer's & dementia : translational research & clinical interventions (2020)
Published in Alzheimer's & dementia : translational research & clinical interventions (2020)
Get full text
Journal Article
Skeletal muscle tissue engineering: A maturation model promoting long-term survival of myotubes, structural development of the excitation–contraction coupling apparatus and neonatal myosin heavy chain expression
Das, Mainak, Rumsey, John W, Bhargava, Neelima, Stancescu, Maria, Hickman, James J
Published in Biomaterials (01.10.2009)
Published in Biomaterials (01.10.2009)
Get full text
Journal Article
Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity
Zechner, Christoph, Lai, Ling, Zechner, Juliet F., Geng, Tuoyu, Yan, Zhen, Rumsey, John W., Collia, Deanna, Chen, Zhouji, Wozniak, David F., Leone, Teresa C., Kelly, Daniel P.
Published in Cell metabolism (01.12.2010)
Published in Cell metabolism (01.12.2010)
Get full text
Journal Article
A defined long-term in vitro tissue engineered model of neuromuscular junctions
Das, Mainak, Rumsey, John W, Bhargava, Neelima, Stancescu, Maria, Hickman, James J
Published in Biomaterials (01.06.2010)
Published in Biomaterials (01.06.2010)
Get full text
Journal Article
Myelination and Node of Ranvier Formation in a Human Motoneuron–Schwann Cell Serum-Free Coculture
Patel, Aakash, Rumsey, John W, Lorance, Case, Long, Christopher J, Lee, Briana, Tetard, Laurene, Lambert, Stephen, Hickman, James J
Published in ACS chemical neuroscience (02.09.2020)
Published in ACS chemical neuroscience (02.09.2020)
Get full text
Journal Article
An induced pluripotent stem cell-derived NMJ platform for study of the NGLY1-Congenital Disorder of Deglycosylation
Sasserath, Trevor, Robertson, Ashley L, Mendez, Roxana, Hays, Tristan T, Smith, Ethan, Cooper, Helena, Akanda, Nesar, Rumsey, John W, Guo, Xiufang, Farkhondeh, Atena, Pradhan, Manisha, Baumgaertel, Karsten, Might, Matthew, Rodems, Steven, Zheng, Wei, Hickman, James J
Published in Advanced therapeutics (01.11.2022)
Published in Advanced therapeutics (01.11.2022)
Get more information
Journal Article
A human induced pluripotent stem cell-derived cortical neuron human-on-a chip system to study Aβ 42 and tau-induced pathophysiological effects on long-term potentiation
Caneus, Julbert, Akanda, Nesar, Rumsey, John W, Guo, Xiufang, Jackson, Max, Long, Christopher J, Sommerhage, Frank, Georgieva, Sanya, Kanaan, Nicholas M, Morgan, David, Hickman, James J
Published in Alzheimer's & dementia : translational research & clinical interventions (2020)
Published in Alzheimer's & dementia : translational research & clinical interventions (2020)
Get full text
Journal Article
Myelination and node of Ranvier formation on sensory neurons in a defined in vitro system
Rumsey, John W, McAleer, Christopher, Das, Mainak, Bhalkikar, Abhijeet, Wilson, Kerry, Stancescu, Maria, Lambert, Stephen, Hickman, James J
Published in In vitro cellular & developmental biology. Animal (01.09.2013)
Published in In vitro cellular & developmental biology. Animal (01.09.2013)
Get full text
Journal Article
Node of Ranvier formation on motoneurons in vitro
Rumsey, John W, Das, Mainak, Stancescu, Maria, Bott, Marga, Fernandez-Valle, Cristina, Hickman, James J
Published in Biomaterials (01.07.2009)
Published in Biomaterials (01.07.2009)
Get full text
Journal Article
Tissue engineering intrafusal fibers: Dose- and time-dependent differentiation of nuclear bag fibers in a defined in vitro system using neuregulin 1- β -1
Rumsey, John W, Das, Mainak, Kang, Jung-Fong, Wagner, Robert, Molnar, Peter, Hickman, James J
Published in Biomaterials (01.03.2008)
Published in Biomaterials (01.03.2008)
Get full text
Journal Article