Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways
Sekhar, Ashok, Rumfeldt, Jessica A O, Broom, Helen R, Doyle, Colleen M, Bouvignies, Guillaume, Meiering, Elizabeth M, Kay, Lewis E
Published in eLife (23.06.2015)
Published in eLife (23.06.2015)
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Journal Article
Probing the free energy landscapes of ALS disease mutants of SOD1 by NMR spectroscopy
Sekhar, Ashok, Rumfeldt, Jessica A. O., Broom, Helen R., Doyle, Colleen M., Sobering, Ryan E., Meiering, Elizabeth M., Kay, Lewis E.
Published in Proceedings of the National Academy of Sciences - PNAS (08.11.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (08.11.2016)
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Journal Article
Effects of maturation on the conformational free-energy landscape of SOD1
Culik, Robert M., Sekhar, Ashok, Nagesh, Jayashree, Deol, Harmeen, Rumfeldt, Jessica A. O., Meiering, Elizabeth M., Kay, Lewis E.
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (13.03.2018)
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Journal Article
Concurrent Increases and Decreases in Local Stability and Conformational Heterogeneity in Cu, Zn Superoxide Dismutase Variants Revealed by Temperature-Dependence of Amide Chemical Shifts
Doyle, Colleen M, Rumfeldt, Jessica A, Broom, Helen R, Sekhar, Ashok, Kay, Lewis E, Meiering, Elizabeth M
Published in Biochemistry (Easton) (08.03.2016)
Published in Biochemistry (Easton) (08.03.2016)
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Journal Article
Combined Isothermal Titration and Differential Scanning Calorimetry Define Three-State Thermodynamics of fALS-Associated Mutant Apo SOD1 Dimers and an Increased Population of Folded Monomer
Broom, Helen R, Vassall, Kenrick A, Rumfeldt, Jessica A. O, Doyle, Colleen M, Tong, Ming Sze, Bonner, Julia M, Meiering, Elizabeth M
Published in Biochemistry (Easton) (26.01.2016)
Published in Biochemistry (Easton) (26.01.2016)
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Journal Article
Calorimetric Analysis of Thermodynamic Stability and Aggregation for Apo and Holo Amyotrophic Lateral Sclerosis-associated Gly-93 Mutants of Superoxide Dismutase
Stathopulos, Peter B., Rumfeldt, Jessica A.O., Karbassi, Farhad, Siddall, Clare A., Lepock, James R., Meiering, Elizabeth M.
Published in The Journal of biological chemistry (10.03.2006)
Published in The Journal of biological chemistry (10.03.2006)
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Journal Article
Nonamyloid Aggregates Arising from Mature Copper/Zinc Superoxide Dismutases Resemble Those Observed in Amyotrophic Lateral Sclerosis
Hwang, Young-Mi, Stathopulos, Peter B., Dimmick, Kristin, Yang, Hong, Badiei, Hamid R., Tong, Ming Sze, Rumfeldt, Jessica A.O., Chen, Pu, Karanassios, Vassili, Meiering, Elizabeth M.
Published in The Journal of biological chemistry (31.12.2010)
Published in The Journal of biological chemistry (31.12.2010)
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Journal Article
Equilibrium Thermodynamic Analysis of Amyotrophic Lateral Sclerosis-Associated Mutant Apo Cu,Zn Superoxide Dismutases
Vassall, Kenrick A, Stathopulos, Peter B, Rumfeldt, Jessica A. O, Lepock, James R, Meiering, Elizabeth M
Published in Biochemistry (Easton) (13.06.2006)
Published in Biochemistry (Easton) (13.06.2006)
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Journal Article
Spectrophotometric method for simultaneous measurement of zinc and copper in metalloproteins using 4-(2-pyridylazo)resorcinol
Doyle, Colleen M., Naser, Dalia, Bauman, Heather A., Rumfeldt, Jessica A.O., Meiering, Elizabeth M.
Published in Analytical biochemistry (15.08.2019)
Published in Analytical biochemistry (15.08.2019)
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Journal Article
Peripheral Ligand-binding Site in Cytochrome P450 3A4 Located with Fluorescence Resonance Energy Transfer (FRET)
Davydov, Dmitri R., Rumfeldt, Jessica A.O., Sineva, Elena V., Fernando, Harshica, Davydova, Nadezhda Y., Halpert, James R.
Published in The Journal of biological chemistry (24.02.2012)
Published in The Journal of biological chemistry (24.02.2012)
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Journal Article
Energetics of oligomeric protein folding and association
Doyle, Colleen M., Rumfeldt, Jessica A., Broom, Helen R., Broom, Aron, Stathopulos, Peter B., Vassall, Kenrick A., Almey, Johnathan J., Meiering, Elizabeth M.
Published in Archives of biochemistry and biophysics (01.03.2013)
Published in Archives of biochemistry and biophysics (01.03.2013)
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Journal Article
Evolution of magnetization due to asymmetric dimerization: theoretical considerations and application to aberrant oligomers formed by apoSOD1(2SH)
Sekhar, Ashok, Bain, Alex D, Rumfeldt, Jessica A O, Meiering, Elizabeth M, Kay, Lewis E
Published in Physical chemistry chemical physics : PCCP (17.02.2016)
Published in Physical chemistry chemical physics : PCCP (17.02.2016)
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