Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
Carravilla, Pablo, Chojnacki, Jakub, Rujas, Edurne, Insausti, Sara, Largo, Eneko, Waithe, Dominic, Apellaniz, Beatriz, Sicard, Taylor, Julien, Jean-Philippe, Eggeling, Christian, Nieva, José L.
Published in Nature communications (08.01.2019)
Published in Nature communications (08.01.2019)
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Journal Article
Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers
Rujas, Edurne, Kucharska, Iga, Tan, Yong Zi, Benlekbir, Samir, Cui, Hong, Zhao, Tiantian, Wasney, Gregory A., Budylowski, Patrick, Guvenc, Furkan, Newton, Jocelyn C., Sicard, Taylor, Semesi, Anthony, Muthuraman, Krithika, Nouanesengsy, Amy, Aschner, Clare Burn, Prieto, Katherine, Bueler, Stephanie A., Youssef, Sawsan, Liao-Chan, Sindy, Glanville, Jacob, Christie-Holmes, Natasha, Mubareka, Samira, Gray-Owen, Scott D., Rubinstein, John L., Treanor, Bebhinn, Julien, Jean-Philippe
Published in Nature communications (16.06.2021)
Published in Nature communications (16.06.2021)
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Journal Article
Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity
Rujas, Edurne, Cui, Hong, Burnie, Jonathan, Aschner, Clare Burn, Zhao, Tiantian, Insausti, Sara, Muthuraman, Krithika, Semesi, Anthony, Ophel, Jasper, Nieva, Jose L, Seaman, Michael S, Guzzo, Christina, Treanor, Bebhinn, Julien, Jean-Philippe
Published in Proceedings of the National Academy of Sciences - PNAS (25.01.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (25.01.2022)
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Journal Article
Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses
Kassardjian, Audrey, Sun, Eric, Sookhoo, Jamie, Muthuraman, Krithika, Boligan, Kayluz Frias, Kucharska, Iga, Rujas, Edurne, Jetha, Arif, Branch, Donald R., Babiuk, Shawn, Barber, Brian, Julien, Jean-Philippe
Published in Cell reports (Cambridge) (25.04.2023)
Published in Cell reports (Cambridge) (25.04.2023)
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Journal Article
The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region
Apellániz, Beatriz, Rujas, Edurne, Serrano, Soraya, Morante, Koldo, Tsumoto, Kouhei, Caaveiro, Jose M.M., Jiménez, M. Ángeles, Nieva, José L.
Published in The Journal of biological chemistry (22.05.2015)
Published in The Journal of biological chemistry (22.05.2015)
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Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease
Sugiyama, Michael G., Cui, Haotian, Redka, Dar’ya S., Karimzadeh, Mehran, Rujas, Edurne, Maan, Hassaan, Hayat, Sikander, Cheung, Kyle, Misra, Rahul, McPhee, Joseph B., Viirre, Russell D., Haller, Andrew, Botelho, Roberto J., Karshafian, Raffi, Sabatinos, Sarah A., Fairn, Gregory D., Madani Tonekaboni, Seyed Ali, Windemuth, Andreas, Julien, Jean-Philippe, Shahani, Vijay, MacKinnon, Stephen S., Wang, Bo, Antonescu, Costin N.
Published in Scientific reports (02.12.2021)
Published in Scientific reports (02.12.2021)
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Journal Article
Functional Delineation of a Protein-Membrane Interaction Hotspot Site on the HIV-1 Neutralizing Antibody 10E8
Insausti, Sara, Garcia-Porras, Miguel, Torralba, Johana, Morillo, Izaskun, Ramos-Caballero, Ander, de la Arada, Igor, Apellaniz, Beatriz, Caaveiro, Jose M M, Carravilla, Pablo, Eggeling, Christian, Rujas, Edurne, Nieva, Jose L
Published in International journal of molecular sciences (15.09.2022)
Published in International journal of molecular sciences (15.09.2022)
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Journal Article
Cholesterol-dependent membrane fusion induced by the gp41 membrane-proximal external region-transmembrane domain connection suggests a mechanism for broad HIV-1 neutralization
Apellániz, Beatriz, Rujas, Edurne, Carravilla, Pablo, Requejo-Isidro, José, Huarte, Nerea, Domene, Carmen, Nieva, José L
Published in Journal of virology (01.11.2014)
Published in Journal of virology (01.11.2014)
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Journal Article
Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface
Rujas, Edurne, Caaveiro, Jose M. M., Partida-Hanon, Angélica, Gulzar, Naveed, Morante, Koldo, Apellániz, Beatriz, García-Porras, Miguel, Bruix, Marta, Tsumoto, Kouhei, Scott, Jamie K., Jiménez, M. Ángeles, Nieva, José L.
Published in Scientific reports (01.12.2016)
Published in Scientific reports (01.12.2016)
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Journal Article
Structural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10
Rujas, Edurne, Gulzar, Naveed, Morante, Koldo, Tsumoto, Kouhei, Scott, Jamie K, Nieva, José L, Caaveiro, Jose M M
Published in Journal of virology (01.12.2015)
Published in Journal of virology (01.12.2015)
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Journal Article
Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments
Rujas, Edurne, Insausti, Sara, Leaman, Daniel P., Carravilla, Pablo, González-Resines, Saul, Monceaux, Valérie, Sánchez-Eugenia, Rubén, García-Porras, Miguel, Iloro, Ibon, Zhang, Lei, Elortza, Félix, Julien, Jean-Philippe, Saéz-Cirión, Asier, Zwick, Michael B., Eggeling, Christian, Ojida, Akio, Domene, Carmen, Caaveiro, Jose M.M., Nieva, José L.
Published in Cell reports (Cambridge) (18.08.2020)
Published in Cell reports (Cambridge) (18.08.2020)
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On the antimicrobial properties and endurance of eugenol and 2-phenylphenol functionalized sol-gel coatings
Suárez-Vega, Ana, Berriozabal, Gemma, Perez de Iriarte, Juan, Lorenzo, Jaione, Álvarez, Noelia, Dominguez-Meister, Santiago, Insausti, Sara, Rujas, Edurne, Nieva, Jose L., Brizuela, Marta, Braceras, Iñigo
Published in Heliyon (30.04.2024)
Published in Heliyon (30.04.2024)
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Journal Article
Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope
Torralba, Johana, de la Arada, Igor, Partida-Hanon, Angélica, Rujas, Edurne, Arribas, Madalen, Insausti, Sara, Valotteau, Claire, Valle, Javier, Andreu, David, Caaveiro, José M. M., Jiménez, María Angeles, Apellániz, Beatriz, Redondo-Morata, Lorena, Nieva, José L.
Published in Communications biology (18.11.2022)
Published in Communications biology (18.11.2022)
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Journal Article
Reply to "The Broadly Neutralizing, Anti-HIV Antibody 4E10: an Open and Shut Case?"
Rujas, Edurne, Gulzar, Naveed, Morante, Koldo, Tsumoto, Kouhei, Scott, Jamie K, Nieva, José L, Caaveiro, Jose M M
Published in Journal of virology (01.03.2016)
Published in Journal of virology (01.03.2016)
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Journal Article
Cholesterol Constrains the Antigenic Configuration of the Membrane-Proximal Neutralizing HIV‑1 Epitope
Torralba, Johana, de la Arada, Igor, Carravilla, Pablo, Insausti, Sara, Rujas, Edurne, Largo, Eneko, Eggeling, Christian, Arrondo, José L. R, Apellániz, Beatriz, Nieva, José L
Published in ACS infectious diseases (14.08.2020)
Published in ACS infectious diseases (14.08.2020)
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Journal Article
Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile
Rujas, Edurne, Leaman, Daniel P., Insausti, Sara, Carravilla, Pablo, García-Porras, Miguel, Largo, Eneko, Morillo, Izaskun, Sánchez-Eugenia, Rubén, Zhang, Lei, Cui, Hong, Iloro, Ibon, Elortza, Félix, Julien, Jean-Philippe, Eggeling, Christian, Zwick, Michael B., Caaveiro, Jose M.M., Nieva, José L.
Published in iScience (24.09.2021)
Published in iScience (24.09.2021)
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