Inosine triphosphate pyrophosphatase from Trypanosoma brucei cleanses cytosolic pools from deaminated nucleotides
Vidal, Antonio E., Yagüe-Capilla, Miriam, Martínez-Arribas, Blanca, García-Caballero, Daniel, Ruiz-Pérez, Luis M., González-Pacanowska, Dolores
Published in Scientific reports (18.04.2022)
Published in Scientific reports (18.04.2022)
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Journal Article
Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine Models
Castillo-Acosta, Víctor M, Ruiz-Pérez, Luis M, Etxebarria, Juan, Reichardt, Niels C, Navarro, Miguel, Igarashi, Yasuhiro, Liekens, Sandra, Balzarini, Jan, González-Pacanowska, Dolores
Published in PLoS pathogens (01.09.2016)
Published in PLoS pathogens (01.09.2016)
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Journal Article
Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi
Bosch-Navarrete, Cristina, Pérez-Moreno, Guiomar, Annang, Frederick, Diaz-Gonzalez, Rosario, García-Hernández, Raquel, Rocha, Hedy, Gamarro, Francisco, Cordón-Obras, Carlos, Navarro, Miguel, Rodriguez, Ana, Genilloud, Olga, Reyes, Fernando, Vicente, Francisca, Ruiz-Pérez, Luis M, González-Pacanowska, Dolores
Published in PLoS neglected tropical diseases (01.09.2023)
Published in PLoS neglected tropical diseases (01.09.2023)
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Journal Article
The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells
Requena, Cristina E, Pérez-Moreno, Guiomar, Ruiz-Pérez, Luis M, Vidal, Antonio E, González-Pacanowska, Dolores
Published in Biochemical journal (01.04.2014)
Published in Biochemical journal (01.04.2014)
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Journal Article
World-Class Long-Distance Running Performances Are Best Predicted by Volume of Easy Runs and Deliberate Practice of Short-Interval and Tempo Runs
Casado, Arturo, Hanley, Brian, Santos-Concejero, Jordan, Ruiz-Pérez, Luis M
Published in Journal of strength and conditioning research (01.09.2021)
Published in Journal of strength and conditioning research (01.09.2021)
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Journal Article
Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei
Valente, Maria, Timm, Jennifer, Castillo‐Acosta, Víctor M., Ruiz‐Pérez, Luis M., Balzarini, Tom, Nettleship, Joanne E., Bird, Louise E., Rada, Heather, Wilson, Keith S., González‐Pacanowska, Dolores
Published in Molecular microbiology (01.11.2016)
Published in Molecular microbiology (01.11.2016)
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Journal Article
The nucleotidohydrolases DCTPP1 and dUTPase are involved in the cellular response to decitabine
Requena, Cristina E, Pérez-Moreno, Guiomar, Horváth, András, Vértessy, Beáta G, Ruiz-Pérez, Luis M, González-Pacanowska, Dolores, Vidal, Antonio E
Published in Biochemical journal (01.09.2016)
Published in Biochemical journal (01.09.2016)
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Journal Article
Kinetic Characterization of Squalene Synthase from Trypanosoma cruzi: Selective Inhibition by Quinuclidine Derivatives
Sealey-Cardona, Marco, Cammerer, Simon, Jones, Simon, Ruiz-Pérez, Luis M, Brun, Reto, Gilbert, Ian H, Urbina, Julio A, González-Pacanowska, Dolores
Published in Antimicrobial Agents and Chemotherapy (01.06.2007)
Published in Antimicrobial Agents and Chemotherapy (01.06.2007)
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Journal Article
Carbohydrate‐binding agents act as potent trypanocidals that elicit modifications in VSG glycosylation and reduced virulence in Trypanosoma brucei
Castillo‐Acosta, Víctor M., Vidal, Antonio E., Ruiz‐Pérez, Luis M., Van Damme, Els J. M., Igarashi, Yasuhiro, Balzarini, Jan, González‐Pacanowska, Dolores
Published in Molecular microbiology (01.11.2013)
Published in Molecular microbiology (01.11.2013)
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Journal Article
Increased uracil insertion in DNA is cytotoxic and increases the frequency of mutation, double strand break formation and VSG switching in Trypanosoma brucei
Castillo-Acosta, Víctor M., Aguilar-Pereyra, Fernando, Bart, Jean-Mathieu, Navarro, Miguel, Ruiz-Pérez, Luis M., Vidal, Antonio E., González-Pacanowska, Dolores
Published in DNA repair (01.12.2012)
Published in DNA repair (01.12.2012)
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Journal Article
Exposure of Trypanosoma brucei to an N-acetylglucosamine-binding lectin induces VSG switching and glycosylation defects resulting in reduced infectivity
Castillo-Acosta, Víctor M, Ruiz-Pérez, Luis M, Van Damme, Els J M, Balzarini, Jan, González-Pacanowska, Dolores
Published in PLoS neglected tropical diseases (01.03.2015)
Published in PLoS neglected tropical diseases (01.03.2015)
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Journal Article
Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase
Cui, Huaqing, Ruda, Gian Filippo, Carrero-Lérida, Juana, Ruiz-Pérez, Luis M., Gilbert, Ian H., González-Pacanowska, Dolores
Published in European journal of medicinal chemistry (01.11.2010)
Published in European journal of medicinal chemistry (01.11.2010)
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Journal Article
Novel Azasterols as Potential Agents for Treatment of Leishmaniasis and Trypanosomiasis
ORENES LORENTE, Silvia, RODRIGUES, Juliany C. F, DE SOUZA, Wanderley, GONZALEZ PACANOWSKA, Dolores, GILBERT, Ian H, JIMENEZ JIMENEZ, Carmen, JOYCE-MENEKSE, Miranda, RODRIGUES, Carlos, CROFT, Simon L, YARDLEY, Vanessa, DE LUCA-FRADLEY, Kate, RUIZ-PEREZ, Luis M, URBINA, Julio
Published in Antimicrobial Agents and Chemotherapy (01.08.2004)
Published in Antimicrobial Agents and Chemotherapy (01.08.2004)
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Journal Article
Acyclic Nucleoside Analogues as Inhibitors of Plasmodium falciparum dUTPase
NGUYEN, Corinne, RUDA, Gian Filippo, SCHIPANI, Alessandro, KASINATHAN, Ganasan, LEAL, Isabel, MUSSO-BUENDIA, Alexander, KAISER, Marcel, BRUN, Reto, RUIZ-PéREZ, Luis M., SAHLBERG, Britt-Louise, JOHANSSON, Nils Gunnar, GONZáLEZ-PACANOWSKA, Dolores, GILBERT, Ian H.
Published in Journal of medicinal chemistry (13.07.2006)
Published in Journal of medicinal chemistry (13.07.2006)
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Journal Article
Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents
Charret, Karen S., Requena, Cristina E., Castillo-Acosta, Víctor M., Ruiz-Pérez, Luis M., González-Pacanowska, Dolores, Vidal, Antonio E.
Published in DNA repair (02.01.2012)
Published in DNA repair (02.01.2012)
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Journal Article
Identification of a residue critical for the excision of 3'-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family
Castillo-Acosta, Víctor M, Ruiz-Pérez, Luis M, Yang, Wei, González-Pacanowska, Dolores, Vidal, Antonio E
Published in Nucleic acids research (01.04.2009)
Published in Nucleic acids research (01.04.2009)
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Journal Article
Intracellular location of the early steps of the isoprenoid biosynthetic pathway in the trypanosomatids Leishmania major and Trypanosoma brucei
Carrero-Lérida, Juana, Pérez-Moreno, Guiomar, Castillo-Acosta, Victor M., Ruiz-Pérez, Luis M., González-Pacanowska, Dolores
Published in International journal for parasitology (01.02.2009)
Published in International journal for parasitology (01.02.2009)
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Journal Article
Kinetic properties and specificity of trimeric Plasmodium falciparum and human dUTPases
Quesada-Soriano, Indalecio, Casas-Solvas, Juan M., Recio, Eliseo, Ruiz-Pérez, Luis M., Vargas-Berenguel, Antonio, González-Pacanowska, Dolores, García-Fuentes, Luis
Published in Biochimie (01.02.2010)
Published in Biochimie (01.02.2010)
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